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National Geographic is entering the next phase of their Genographic Project in partnership with Family Tree DNA and the genetic genealogy community. Are there discounts available for first-phase participants who want to purchase a Geno 2.0 kit? We are offering first-phase Genographic participants a limited-time discount of $30 on the Geno 2.0 kit. IMPORTANT NOTE: If you are an existing FTDNA customer, please do not pre-order through National Geographic at this time.
Question: Custom Illumina chip was vetted by running against 400 pre-existing WTY samples, finding over 5,000 new nodes to add to the haplotree.
1) I think the FMS mtDNA will become the WTY equivalent where new mutations could be discovered and the Geno 2.0 will test 95 % of the known mtDNA mutations that are currently known.
2) I looks like November, 2011 was the cutoff for adding any new content to the custom plate being used. Like computers DNA testing has a higher price tag at the beginning and then 3 years down the road it's almost obsolete with the new tests coming along---but that's just the price we pay for incredibly rapid acceleration of the field. This will bring hundreds of new people to our haplogroup forums who will ask for assistance to interpret the results - so these forums will be swamped with data and requests to analyze the data. These are additional remarks from rootsweb on the new chip with some additional information by various people. Dwight and others,Perhaps John Olson will allow data from the new test to be uploaded to GEDmatch for matching purposes, particularly if the data has already been phased before it is uploaded. This test will have value both for individuals who have identified their haplogroup via advanced SNP testing and for those who are interested in deeper ancestry information.
After this new chip was created by Illumina specifically for NationalGeographic, about 1200 samples were run as proof of concept, including 400WTY (Walk the Y), 350 mitochondrial full sequence and 500 Y samples. Just based on this test run alone of 900 Y chromosome kits, the haplotreeexpanded from 862 SNPs to a total of 6153. Since the only SNPs on the chip are ones already found by some other method,this apparently means that Geno 2.0 is finding thousands of additionalinstances of known SNPs. I am still afraid that some will opt for this test instead of the FMS or full-sequence mtDNA test.
That would have been when the current quite outdated version of the deep clade test was established. If I am reading this correctly as to the time when these SNPs were chosen for the chip, all the important discoveries since early 2011 will be ignored in Geno 2.0 and we are back to buying $29 tests for each of these new Z and L SNPs since the last deep clade test. Bennett Greenspan was gracious enough to call me with the answers to several questions and responses to comments and speculation on blogs and lists today. Q: Does Family Tree DNA plan to offer a test that will be more extensive then the new Genographic test for the Y chromosome? By way of example, in haplogroup R-M222 ? the new Geno chip includes discoveries of at least three unique SNP?s downstream of R-M222. These 10,000 new SNPs will provide, for almost everyone, one or two additional clades (subhaplogroups) down the tree from where they are located today. A: FTDNA is vetting the Y tree in conjunction with the Genographic Project and prior to the release of these data. Q: What is the difference between the full mitochondrial sequence (FMS) test and the Geno 2.0 test for mitochondria? If you want your anthropological information, meaning haplogroup information only, then the Geno 2.0 kit is the way to go. Lots of folks have had questions about the Geno 2.0 kits and different aspects of the testing. Genographic is a non-profit National Geographic research project focused on mapping the human journey, and encompasses three core components: scientific research, public participation and the Legacy Fund. I assume you are referring to the chromosomal ?painting? on the 23andMe website, and no ? at this time we don?t offer this feature. We are continuing to refine our analysis of the chip data, and may be expanding our list of regional affiliations. It?s all about the markers: again, because we have created our chip specifically for the study of ancestry, we feel that it is the most accurate tool for determining population affiliation. Here is the abstract of a paper to be presented at a 6 Nov meeting of the American Society of Human Genetics. Methods: Our goal was to design, produce, and validate a SNP array dedicated to genetic anthropology. Conclusions: The GenoChip is the first genotyping chip completely dedicated to genetic anthropology with no known medically relevant markers.
A molar tooth found at the archaeological site of Denisova cave provided crucial genetic evidence for the existence of the Denisovansa€”a hominid species discovered in only 2010. The analysis of a fossil tooth from Siberia reveals that a mysterious people known as Denisovans, discovered a mere five years ago, persisted for tens of thousands of years alongside modern humans and Neanderthals. The find underscores that our Homo sapiens ancestors shared the Eurasian continent with other human-like populations. The new study, published Monday in the Proceedings of the National Academy of Sciences, marks an important step in scientistsa€™ understanding of where Denisovans fit in the human family tree. The DNA from the previously analyzed finger bone and tooth show that Denisovans left their mark on modern humans, contributing about five percent of the genome of modern Melanesians, who live in Papua New Guinea and other parts of the Pacific.
A replica of the bone chip that permitted the discovery of the Denisovans balances on the pinky finger of evolutionary geneticist Svante PA¤A¤bo. But researchers still knew next to nothing about the hominids, other than their existence and the genetic shadow they cast on the present. Viola found that the two teeth were consistent with one another and different from those of  modern humans and Neanderthalsa€”strongly suggesting for the first time that large teeth were part of the Denisovan package.
Though ita€™s difficult to say what large-toothed Denisovans would have looked likea€”wisdom teeth have notoriously variable shapesa€”therea€™s little doubt that a€?large teeth with massive roots would probably require massive jaws,a€? says Viola. The results also underscore the innovative genetics that anthropologists are increasingly using to pull back the veil of time. Susanna Sawyer of the Max Planck Institute for Evolutionary Anthropology led the genetic effort to describe and date the recently found tooth.
Student Zoya Gudkova takes a break while excavating in Denisova cave, in Siberiaa€™s Altai Mountains.
Her team homed in on the tootha€™s mitochondrial DNA, a portion of genetic material that holds up better in fossils over time. Once Sawyer had the new tootha€™s mitochondrial DNA in hand, she was able to verify that it indeed was Denisovan. The common ancestora€™s DNA provided the team with an important baseline, calibrating a genetic stopwatch that accrues mutations with each tick. The discrepancy suggests that the Denisovan to whom the tooth belonged lived about 60,000 years before the individuals who left behind the finger bone and the other tooth. For starters, the researchers dona€™t actually know how old the Denisovan fragments are, except that theya€™re more than 50,000 years old, the oldest dates that radiocarbon dating can reliably provide. And when it comes to the actual branching of the human family tree, the recent findings seem to conflict with the 2010 studies, which analyzed DNA found in cellsa€™ nuclei instead of mitochondrial DNA.
It doesna€™t help that scientists know next to nothing about how Denisovans looked, moved, and behaved.
Fortunately, there may be other hidden Denisovans scattered throughout Asia, accidentally mislabeled in museums as human or Homo erectus, an ancient hominid ancestor. But researchers wona€™t know for sure if the Denisovans are hiding in plain sight until they conduct further genetic tests. Tingly bubble shooter game 108game mobile, Tingly bubble shooter is a fun and colorful arcade bubble shooter game by tingly. We have an collection of National Geographic And Family Tree Dna Announce Geno 20 in various styles.

Genetic testing on 11 mummies revealed the remains of Tut’s parents, who were brother and sister.
Select a button below to see how these distinct genetic markers are passed from Yuya (orange), Tuyu (blue), and Amenhotep (violet). The Genographic Project, in partnership with Family Tree DNA, announces a new evolutionary tree.
What is the 2014 Y-Tree? The new Y-Tree is a chart of human relatedness showing how all men’s Y-chromosomes stem from an ancient ancestor in Africa more than 100,000 years ago. How different is the 2014 Y-tree to the current version used by the Genographic Project? With the new tree the number of branches nearly doubled, from 667 to more than 1200, and new connections have emerged. Geno 2.0 is apparently misclassifying members of Y-DNA haplogroup A into other haplogroups. What difference does it make where you are located on the tree whether it is version 1, 2, 3 or n. So pleased with the National Geographic & FTDNA partnership in mapping the human story! I am in Y-DNA Haplogroup R1b-L371 which was discovered in 2011 and which has been on the Official ISOGG Y-Tree for more than 3 years. National Geographic VoicesResearchers, conservationists, and others around the world share stories and commentary on the National Geographic Society's conversation platform Voices. Society Field Inspection 2016: Gulf of CaliforniaDescribed by Jacques Cousteau as the "aquarium of the world," the Gulf of California in Mexico is threatened by coastal development, climate change, and other human activities. Support National GeographicWe've supported more than 11,000 grants to scientists and others in the field.Learn more about our work.
Two years after being discovered deep in a South African cave, the 1,500 fossils excavated during the Rising Star Expedition have been identified as belonging to a previously unknown early human relative that National Geographic Explorer-in-Residence Lee Berger and team have named Homo naledi.
With at least 15 individuals of all ages and both sexes represented, the find adds an unprecedented amount of information to our understanding of early human evolution in Africa.
In addition, the absence of any other animal remains or large debris in the fossil chamber strongly suggests that these non-human beings intentionally deposited their dead within this cave. Continuing to move toward their goal of mapping the pattern of human genetics, they are introducing the new GenoChip 2.0. Some of this may be duplicated but just trying to get information to our members about this product and how it affects their testing. There is no advantage to doing so, it will likely cost you more, and at this point, it is not at all clear what will happen if you do so -- you may end up with some test results under your current kit, and the Geno 2.0 results underneath a different kit number. Will customers be able to order an "upgrade" for their sample and obtain this data, sooner than later? Since the mtDNA structure is only 16,000 base pairs, there are probably not a whole bunch more mutations to be found since 3,300 have been found to date. And I agree with your recommendation to test a brother (if you have one) for the y info---really should be discounted for women. Eliminates the medical and identity issues, works to FTDNA's strengths and ties into the power of National Geographic.
I am sure that it will approach the scope of the full mtDNA test - so it is questionable at this point in time if the current mtDNA tests will provide enough added value to make the extra expense worthwhile. We will have to learn how to collect all this new data - my recommendation is to wait for FTDNA's offering as it will include putting the results into their database vs. The new Geno 2.0 product has 130,000 SNPs, but they are focused on specific areas of ancient ancestry.
However, if someone has already done Family Finder or 23andMe and uploaded that data to GEDmatch I don't think that the new Geno 2.0 test will add very much to the value of Family Finder or 23andMe in terms of generating matches.
It would depend on the SNP properties -- how they're distributed over the chromosomes, the amount of linkage disequilibrium, the minor allele frequencies in the relevant population, and so forth. We need to consider that due to the number of offered SNPs there is a reasonable chance that one will be able to identify a SNP, say M365.xx, which help define your paternal line within a genealogical time frame. Only a few of the 2338 Z-series of candiate SNPs in the 1000 Genomes Project were identified or the thousands of singleton SNPs. He talks about the relationship with National Geographic and how their products and Familytreedna products can be used in genetic genealogy. He wants to thank everyone for their interest and personal support for the ongoing research and the new product. The most extensive test for obtaining YDNA SNP data is available on the Geno 2.0 chip and Family Tree DNA has no plans to compete with its partner.
Wells for his willingness to engage our community and to share further details on this exciting subject with us.
The project is non-profit and non-medical, and through the sale of its public participation kits it supports cultural preservation efforts in indigenous and traditional communities. For hundreds of thousands of years, modern humans lived alongside Neanderthals, a sister hominid species that died out about 40,000 years ago.
The new DNA also allowed Sawyer to reconstruct the mitochondrial genome of the common ancestor of the  three individuals found in the cave. Denisovans who died closer to the common ancestora€™s time would have fewer mutations in their genomes than more recent Denisovans would. At a minimum, this miniature family tree shows that the Denisovans were a single biological group that sporadically inhabited the region for at least as long as modern humans have. The new study suggests that Denisovans are not as closely related to Neanderthals as the previous findings indicated. In particular, the studya€™s authors point to recent finds in southern China, where anthropologists have uncovered human teeth between 80,000 and 120,000 years old that share modern and ancient features, much like the Denisovan teeth. Here is some inspiring pictures about National Geographic And Family Tree Dna Announce Geno 20. In order to join in on the festivities and mark this calendric coincidence, National Geographic’s Genographic Project and Family Tree DNA are announcing the joint creation of the newest, largest, and most refined evolutionary tree of the paternally-inherited Y chromosome.
Since that shared common ancestor, his descendents have journeyed around the world and in the process accumulated mutations in their DNA that make them and their Y-chromosome relatives unique. Haplogroup O, for example, has changed form showing new patterns of relatedness among East Asians and Southeast Asians. By joining the Genographic Project your sample was compared to that of thousands of other participants, and your shared, but also your unique mutations helped us better understand the evolutionary process in which mutations occur, and thus helped us reconstruct the chronological order of mutations. The Genographic Project team is working closely with Family Tree DNA to implement the new data now. It is such an enormous undertaking – I am thrilled to be able to pass on this information to my 3 grandsons in a very personal application (what is your link via haplogroups you were born with for example my mtDNA haplogroup U5a1b*) and genetic links to DNA relatives. They put rank and file Genetic Genealogists (who pay for all these DNA tests) BEHIND their own financial and academic needs. Posters and commenters are required to observe National Geographic's community rules and other terms of service. To learn firsthand what's going on in and around this marine treasure of global importance, the National Geographic Society sent its top scientists and officials to the region in January 2016. This chip is specifically designed for ancestry testing and includes SNPs from autosomal DNA, X-DNA, Y-DNA and mtDNA.
To receive this discount, you will need to have purchased the first generation Genographic Project Participation Kit. Please give FTDNA a chance to clarify what current customers should do to make sure we don't end up with an IT nightmare. So all those who tested FMS mtDNA as well as those with HVR1 and HVR2 testing will have their mutations included. The must have data mined a lot from the Roche 454 scanner (thought to be the new WTY scanner). This is really good news for those of us that would like to see FTDNA remain a big player for the long term.

130,000 is not enough to do the FF type of matching, so both of these tests are useful for different purposes.
I have a sneaky hunch that the deep clade price increase last spring was FTDNA's method of doing the same thing. The higher SNP densities in FF and RF may include lots of redundancies: if you have a particular allele for one SNP, you are highly likely to have a particular allele for the neighboring SNP (the definition of linkage disequilibrium). In a few months, we'll have some empirical data to examine this question, but I would hazard a guess that Geno 2.0 could have some predictive value for 2nd cousin relationships.
But if someone runs Geno 2.0 on a member of the EuropeanN1* clade, he will find that clade to be P189+ also.
Some of the Z SNPs have filled in major gaps in the haplogroup trees for a number of haplogroups. I don't have the exact date and don't quote me, but didn't I just read someone said up until November 2011 on one of the threads?
He asked me to share some information with the community regarding the sources of the Y-SNPs included on the chip that will be used for Geno 2.0.
To extend our knowledge of the human journey, interbreeding with ancient hominins, and modern human demographic history, we designed a genotyping chip optimized for genetic anthropology research. To determine the extent of gene flow from archaic hominins to modern humans, we included over 25,000 SNPs from candidate regions of interbreeding between extinct hominins (Neanderthal and Denisovan) and modern humans. The ~10,000 novel Y SNPs included on the chip have greatly refined our understanding of the Y-chromosome phylogenetic tree. The dental analysis fell to Bence Viola, an anthropologist of the University of Toronto who had examined the first Denisovan wisdom tooth and initially mistook it for the tooth of a cave bear, given its size and huge, splayed roots.
Sawyer found that the recently discovered tooth had half the number of mutations of the other remains, suggesting it was older. Click image to get bigger picture, and if you find National Geographic And Family Tree Dna Announce Geno 20 interesting, you might pin it to Pinterest.
Each mutation is a genetic event that occurred at a particular time and place in the ancestral journey. In general, the overall structure of the tree remained consistent with past versions, thus not affecting participants’ major haplogroup designations (G, J, R, and so on). However, if they do they would become more specific, thanks to the increase in our understanding of the branching patterns and the discovery of new branch tips on the tree. In the next few weeks this process will be complete and announced on the Genographic Project website. None of this could have been possible without any aspect of research, Spencer Wells, FTDNA & of course citizen scientists who donate money to be tested and their DNA! They toured the desert islands off the southeastern coast of the Baja Peninsula and they listened to presentations by more than a dozen experts, including several whose Baja California research is funded by the Society.
The design of the new chip was a collaborative effort between Eran Elhaik of Johns Hopkins, Spencer Wells of National Geographic, Family Tree DNA and Illumina. Participants who who did not purchase the first generation kit, but received the kit as a gift are not eligible for this discount.
With 10,000 new Y-SNPs from around 1,000 submissions (probably 10M base pairs from the 454 scanner) - there is going to be a lot of new raw data to absorb and understand. It will include a lot of redundant SNPs, SNPs where position not clear and a lot very old SNPs 2,000 to 20,000 years old.
FTDNA will probably offer a upload your Nat Geo data for a small fee at some point in time since FTDNA is the lab where these tests are run. Back in the days when DNAPrint was in business, Tony Frudakis estimated that ~100 autosomal SNPs were as good as the 13 CODIS STR markers for paternity testing. 23andMe currently assigns deep subclade designations based on about 15% of the mtDNA sequence. Additional important SNPs were found in Walk through the Y testing from the L-series in the last year and a half.
He also commented on the role that he envisions for our citizen scientists within the genetic genealogy community in partnership with Geno 2.0. Looking forward to investigating the raw data and looking at National Geographics take on the data from the chip.
To avoid any inadvertent medical testing we filtered out all SNPs that have known or suspected health or functional associations.
By including Y and mtDNA SNPs on an unprecedented scale, the GenoChip is able to delineate extremely detailed human migratory paths. And did Denisovans really have such massive teeth, or did researchers happen upon a biological oddity? And the success of the DNA tree is due in great part to the Genographic Project’s GenoChip and the help from the more than 600,000 people that have joined this one-of-a-kind participant science project.
Today, all men carry in their Y-chromosomes a set of DNA mutations that charts that series of events.
It will surely include all 60 or so R-L21 SNPs that we know about which now available at $29 per SNP. You also get this already with Family Finder but that is a very small portion of the Family Finder test.
I see this as an opportunity for the community to take an active role in helping us to build the definitive Y-chromosome tree.
We validated the chip by genotyping over 1,000 samples from 1000 Genomes, Family Tree DNA, and Genographic Project populations. The autosomal and X-chromosomal markers included on the GenoChip have revealed novel patterns of ancestry that shed a detailed new light on human history. Scientists collected DNA, then looked at eight sets of genetic markers (colored boxes in diagram below) to create a genetic fingerprint for each mummy. The tree is therefore the global genetic map of all these mutational events, showing how we are all related.
The exome is apparently excluded from the new Geno 2.0 test, so that will exclude coverage of about 5% of the genome. This test will no doubt do a good job in determining their subclade up to the level of PhyloTree Build 14, probably better than 23andMe. Interbreeding analysis with extinct hominids confirmed some previous reports and allowed us to describe the modern geographical distribution of these markers in detail. It will probably take them 5 years to update their Y-Tree with my ~14 NEW & NOVEL YSNPs. The above implies that they may have behind the scenes used the 454 scanner to re-scan all 400 previous WTYs - what a deal for those people. Unfortunately, many women will order this test (they really should not) as the Y-chromosome will be empty. You can probably assume that the other 500 were very geographically diverse in order to meet Nat Geo desire to properly address the world's haplotree vs. Please be a little more succinct about what you are really capable of doing and why it takes three or more reviews of the same sample to provide the full data. I think that this is something that we should encourage FTDNA and the Genographic Project to do. As of now, FTDNA still needs to redesignate most of their those with FMS results to the level of Build 14, which was released over three months ago.

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