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Although stem cell therapy has been used for over 40 years, it still holds enormous untapped potential for both science and medicine.
Stem cells have two fundamental properties that make them particularly interesting for medical research: They can divide indefinitely and produce identical copies of themselves.
Medical researchers anticipate being able to use technologies derived from stem cell research to treat a wider variety of diseases including cancer, Parkinson's disease, spinal cord injuries, and multiple sclerosis, amongst a number of other impairments and conditions.
Stem cell research remains a controversial issue, especially in relation to human embryonic stem cells. To leave the situation as it currently stands is not viable in the long-term, as future research in this area holds the promise of treating serious debilitating diseases for which currently no treatments are available – such as Parkinson’s or heart disease. Sir John Gurdon and Shinya Yamanaka won the 2012 Nobel Prize of medicine for their work on the reprogramming of adult cells back into embryo-like stem cells that can be used as replacement tissue for damaged brain or heart cells. Beta BlockersScientists are still trying to figure out how exactly beta blockers cause depression, but common side effects that have been reported are fatigue, changes in sexual behavior, and general feelings of depression. CorticosteroidsCorticosteroids reduce the amount of serotonin your body produces, which can lead to feelings of depression. Benzodiazepine HypnoticsBenzodiazepine hypnotics medicines can be used to treat anxiety and insomnia, but it can also depress the system, as they are sometimes not fully digested by the liver. Parkinson’s DrugsSome drugs used to treat Parkinson’s disease can be sources of depression. StimulantsStimulants can be used to treat a bevy of medical issues from narcolepsy to ADHD. AnticonvulsantsAnticonvulsants have historically been used to treat seizures, but some physicians have started treating other medical conditions, such as mood disorders, with anticonvulsants. Proton Pump Inhibitors and H2 blockersProton pump inhibitors and H2 blockers are used to treat gastroesophageal reflux disease. Statins and Other Lipid-Lowering DrugsUsed to lower cholesterol, statins and other lipid-lowering drugs can lead to feelings of depression by reducing levels of cholesterol in the brain.
Anticholinergic Drugs Used to Treat Stomach Cramps and Other GI DisordersAnticholinergic drugs interact with your central nervous system, and can sometimes lead to depression.
If you think your feelings of listlessness and fatigue could be a side effect of the medicine you are taking, talk to your doctor to see what other options are available to you to treat your medical condition. This entry was posted in Health Information, Prescriptions & Medicine and tagged Anticonvulsants, Benzodiazepine Hypnotics, Beta Blockers, Depression, Hormone Altering Drugs, Medication, Parkinson’s Drugs, Prescriptions, Stimulants.
This summary by Helle Bogetofte was shortlisted for Access to Understanding 2014 and was commended by the competition judges. Access to Understanding entrants are asked to write a plain English summary of a research article.
Here you have a list of opinions about parkinsons disease and you can also give us your opinion about it.


You will see other people's opinions about parkinsons disease and you will find out what the others say about it. In the image below, you can see a graph with the evolution of the times that people look for parkinsons disease.
Thanks to this graph, we can see the interest parkinsons disease has and the evolution of its popularity. You can leave your opinion about parkinsons disease here as well as read the comments and opinions from other people about the topic. Adult stem cell therapies already exist, notably in the form of bone marrow transplants used to treat leukaemia. These are particularly promising because they bear unlimited potential to produce specialised cells, which suggests enormous possibilities for disease research and for providing new therapies.
Additionally, to close down such a vital avenue of research would be a massive blow to European science and innovation.
In the long-term, the discovery could lead to the creation of replacement tissues for treating diseases like Parkinson’s or diabetes. Patients can use alternatives, such as aspirin or a doctor-prescribed mild opiate in place of corticosteroids to avoid feelings of depression brought on by these medications. Alternatives to these drugs would be setting a strict sleep schedule, as going to bed and waking up around the same time every day can help reduce symptoms that would otherwise be treated with benzodiazepine hypnotics. These drugs increase dopamine levels, and researchers believe prolonged exposure to dopamine leads to depression. These types of drugs, like drugs used to treat Parkinson’s disease increase levels of dopamine in the brain.
Anticonvulsants work by depressing your central nervous system, and as such, there is a chance that taking these drugs could lead to depression. Researchers are unsure of how these drugs cause depression, but you may be able to avoid taking them by knowing which foods trigger your acid reflux and avoiding them or eating them in moderation. Alternatives such as B vitamins and folic acid can also be used to treat high cholesterol levels. Alternatives to Anticholinergic drugs used to treat stomach cramps and other GI disorders include H2 blockers, such as Zantac. It is important that you do not stop taking a medication suddenly and without consulting your doctor. In this structure inside the nucleus, proteins and RNA molecules are assembled, forming ribosomes, the cells’ protein factories.In spite of worldwide research efforts, Parkinson’s disease’s molecular causes are still not clear. And below it, you can see how many pieces of news have been created about parkinsons disease in the last years.
In the future, medical researchers anticipate being able to use technologies derived from stem cell research to treat serious debilitating diseases for which no treatments are currently available, including Parkinson's disease and spinal cord injuries.


Stem cell therapy is already proving its therapeutic potential with the first European-developed therapy based on human embryonic stem cells (hESCs) approved in 2012 by the European Medicines Agency for a treatment for age-related macular degeneration, a cause of sight loss and blindness.
In the case of stem cells, we are no longer talking about nebulous promises for the future, but about therapies within tangible reach. Researchers again suggest reviewing your medications if feelings of depression begin to emerge and discussing alternative treatment options with your doctor. Researchers have explored if the nucleoli’s demise also plays a part in Parkinson’s, also referred to as “shaking palsy”.Neurons that produce dopamine inside the brain of individuals with Parkinson’s were microscopically examined. Standing still is not an option for the EU in this hugely promising and increasingly competitive field. The European Pharmaceutical industry is supporting medical progress with the creation of a stem cell bank by the Innovative Medicines Initiative (IMI), the world’s largest public-private partnership.
Despite these benefits, there are strong lines of divisions throughout EU Member States on the issue of stem cell research.
Relocation of this research will not make it disappear; it will just slow access for European patients to the fruits of this research. This kind of cell malfunctions and dies in Parkinson’s, resulting in the typical palsy symptoms. Currently, not all EU Member States allow embryonic stem cell research and many of these countries are pushing for its exclusion from EU budget lines. Most nucleoli were in fact discovered to be defective inside these cells.This discovery led the researchers to take a look at if disrupted nucleoli can really result in Parkinson’s-like symptoms or if this was just an incidental discovery. EFPIA believes that these concerns should be balanced with the needs of patients for new medicines and vaccines. Mice’s DNA were modified in a manner that only defective nucleoli could be formed by the cells producing dopamine. Their brain’s neurons producing dopamine died prematurely as well.The scientists look more closely at all the genetically modified cells’ functions to determine why these symptoms take place.
A significant change was discovered: The mTOR enzyme’s activity was reduced in the cells that were genetically modified. Due to reduced mTOR activity, a key intracellular signaling pathway regulator, the function of the cell’s power plants, the mitochondria, is disrupted. This can result in major damage to cells and could be a key prerequisite for Parkinson’s disease’s characteristic nerve damage. The researchers aren’t however sure if the nucleoli damage is really the only reason for this neurodegeneration.



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Comments to «Can parkinsons disease cause hearing loss»

  1. joni writes:
    Relief immediately, but a noticeable difference eardrum.
  2. Tanchor writes:
    Wave hits it and so the sound is muffled tinnitus signal and the severity.