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Hearing Impairment Sensorineural hearing loss Noiseinduced hearing loss Postlingual deafness Deaf culture Otosclerosis Unilateral hearing loss Hearing aid Auditory brainstem response, Unknown Author. Hearing Impairment Sensorineural hearing loss Noise-induced hearing loss Post-lingual deafness Deaf culture Otosclerosis Unilateral hearing loss Hearing aid Auditory brainstem responseHearing impairment. By using this Web site, you confirm that you have read, understood, and agreed to be bound by the Terms of Use.
Objective: The purpose of this study was to observe the effectiveness of immune modulator –Inosine Pranobex (Isoprinosine) in the treatment of sudden sensorineural hearing loss of suspected viral origin. Setting: This study was performed in the Clinic of Otorhinolaryngology in the Medical Institute of Ministry of Interior, Sofia. Patients: The study included 28 patients with sudden hearing loss of suspected viral origin, divided randomly into two groups.
Intervention: The first group of 14 patients was treated with corticosteroids and vasodilators. Main Outcome Measures: The patients passed precise otorhinolaryngological examination, pure tone audiometry, speech audiometry, stapedial reflex testing, ABR, CT scan, hematological testing –complete blood count (CBC) and sedimentation rate, biochemistry and serologic testing for syphilis.
Results: We compared the two groups before and after the treatment regarding mean hearing level at each frequency, speech reception threshold improvement, and tinnitus and balance complaints. Conclusions: Administration of a combination of corticosteroids, vasodilators and immune-modulator should be recommended for treatment of patients with sudden sensorineural hearing loss. Sudden sensorineural hearing loss is defined as 30 dB or more sensorineural hearing loss over at least three contiguous audiometric frequencies occurring within 3 days or less. The vascular courses include vasospasm, thrombosis, embolism, hemorrhage, hypercoaguability and rheologic abnormalities.
The viral-vascular combination theory suggests that a viral infection initiates a hypercoagulable state secondary to the effect of viruses on the vascular system.
The therapy that has been proven to be effective in the treatment of sudden sensorineural hearing loss is the etiologic based one. 28 patients of either gender (24 male and 4 female), aged between 12 and 47 years with sudden hearing loss were enrolled in the study.
Pure tone audiometry was performed weekly during the first 14 days of the treatment, 4 weeks after the onset of the disease and 2 months later. After 14 days of the treatment in the Clinic of Otorhinolaryngology and 2 weeks more at home, the results were as following in Table 2.
We compared the two groups before and after treatment regarding mean hearing level at each frequency, speech reception threshold improvement, and tinnitus and balance complaints. It is not surprising that the cochleovestibular blood supply may be affected by circulatory disorders such as embolic phenomenon, thrombosis, vasospasm and hypercoagulable or high viscosity states resulting in sudden sensorineural hearing loss.
Administration of a combination therapy of corticosteroids, vasodilators and immune-modulator should be recommended for treatment of patients with sudden sensorineural hearing loss of suspected viral origin. Unilateral Hearing Loss Wikipedia The Free Encyclopedia article Sensorineural hearing loss (snhl) is a type of hearing loss, or deafness, in which the root cause lies in the inner ear or sensory organ (cochlea and associated. Copyright © 2014 Special Gift, All trademarks are the property of the respective trademark owners. Classic stigmata of congenital syphilis SNHL, interstitial keratitis, Hutchinson teeth (notched incisors), mulberry molars, Clutton joints (bilateral painless knee effusions), nasal septal perforation & saddle deformity& frontal bossing. Text-to-text communication systems are interactive face-to-face communication tools that provide a means of communicating with your customers or employees. Auditory alarms, whether activated by heat, smoke, or toxic fumes, warn of imminent danger by sound. A wireless paging system, connected to your fire panel, immediately notifies users of emergency situations via a vibrating pager, or by sending a text message to LCD displays placed throughout your facility, keeping everyone in your place of business aware of emergency alerts. Perfectly suited for a main switchboard, call centre environment, employee access, and enterprise wide TTY telephone service using multiple lines. TTY with a built in printer and an answering machine make this TTY the ideal unit for any business interested in making their services more accessible to people who communicate by TTY.
There’s an old joke in the business world.  Two managers talk about the cost of training their employees. Useful, brief articles from CHS and ORHMA on technology solutions, how to obtain funding for support for Deaf or hard of hearing staff, investing in talent for long-term success and communication tips. The second group of 14 patients was treated with corticosteroids, vasodilators and immune modulator - Isoprinosine. The patients with vertigo passed observation for nystagmus, static and kinetic tests, posturography and electronystagmography (ENG).
4 patients recovered totally, 19 patients improved their hearing with 20 dB and 5 patients showed no improvement. The phylogenetically newer portion of the inner ear, which includes the cochlea and saccule, is relatively more susceptible to various agents than the pars superior. Experimental studies have shown that the ganglion cells are the most sensitive to ischemia, while the pathologic data indicates that the organ of Corti, stria vascularis and tectorial membrane are the predominant structures affected in cases of sudden sensineural hearing loss (7).


One of the mechanism by which hearing loss develops is through changes in cellular immunity.
We used a combination of medicines, according to the viral-vascular etiologic theory (8-10). 8 patients noted their hearing loss upon first awakening in the morning, 2 patients – after stress situation, 18 patients had in their history a viral upper respiratory infection as 2 patients were in contact with varicella – infected persons, 1 woman was with rubeolla and 15 patients had in their history symptoms of influenza. Ophthalmologic, neurological and rheumatologic consultations were carried out to rule out systemic vasculitic diseases. The vascular etiologic theory is favored because of the sudden nature of the onset of hearing loss.
This type of treatment result in earlier hearing recovery and less extensive cochlear destruction compared to steroids and vasodilators.
Therapy of idiopathic sudden sensorineural hearing loss: antiviral treatment of experimental herpes simplex virus infection of the inner ear.
Oral steroid treatment of sudden sensorineural hearing loss: a ten-year retrospective analysis.
Treatment of idiopathic sudden sensorineural hearing loss with antiviral therapy: a prospective, randomized, double blind clinical trial.
Recovery of hearing: results of delayed medical treatment in patients with idiopathic sudden hearing loss. Skeletal findings osteochondritis& periostitis of long bones SNHL, interstitial keratitis, Hutchinson teeth (notched incisors), mulberry molars, Clutton joints (bilateral painless knee effusions), nasal septal perforation & saddle deformity& frontal bossing. These portable systems enable people who are Deaf or have a hearing loss to communicate face-to-face instantly. For customers or employes who are Deaf or have hearing loss, these life saving emergency notification measures fail completely. They are designed to connect the sound from the main speaker, sound system or other audio source and send the signal directly to wireless receivers worn by people with a hearing loss. Consisting of one or more microphones and one or more loudspeakers, Soundfield Systems provide even sound coverage within a room. This software solution allows you to answer incoming calls and make TTY calls directly from your computer station.
Whether you are running a small coffee shop or a grand hotel, the core of your business is creating a space where people who walk in want to stay. Here are a few tips for communicating face-to-face with someone who is culturally Deaf, oral deaf, deafened or hard of hearing. Here are some simple, affordable strategies you can use to remove barriers in your restaurant, hotel, or motel, to make every guest feel welcome. Learn her story and others, and how to recruit people who are Deaf or hard of hearing to work at your hotel or motel. In this video, you’ll learn their stories and others, and find out more about hiring Deaf and hard of hearing for your own restaurant. The findings in animal models of hearing loss of vascular origin are of extensive cochlear fibrosis and ossification. The otorhinolaryngologic examination included otoscopy, anterior rhinoscopy and pharyngoscopy. The treatment of sensorineural hearing loss often proves to be frustrating to the clinician as, in the majority of cases, the etiology is unknown and the underlying disease process is irreversible.
The underlying pathophysiology can be explained by the occurrence of sudden anoxic injury to the cochlea.
The recovery is significantly related, as well, to onset of hearing loss and audiogram type. The receivers allow individuals to adjust the volume to a comfortable level and can be used with a variety of headsets, including neckloop listening accessories for those with telecoil equipped hearing aids. An internet based solution integrates the telephone network, the data network, and the internet to provide fully accessible text (TTY) communication.
On average, it costs under $500 to accommodate an employee with a disability, although the exact amount will depend on the individual needs. Sudden hearing loss may be idiopathic but also significant differential diagnoses must be considered.
Additional evidence of that type of etiology is indicated by the fact that patients had substantial hearing improvement with mono steroid treatment. Otorhinolaryngologists make efforts to treat the sudden sensorineural hearing loss according to the established etiologic courses as viral, vascular or viral-vascular combination (11-15). Effects of anoxia result in changes in the cochlea microphonics with loss of the action potential. So the combination of immune-mediator (Isoprinosine), corticosteroid (Methylprednisolon) and vasodilator (Cavinton) proved to be effective in treatment of sudden sensorineural hearing loss. Treatment aimed at the possible etiologic agent might be beneficial only in the very early phase of the hearing loss.


Assistive Listening systems help to reduce background noise and compensate for poor room acoustics or distance from the sound source. It is the most flexible amplification solution for classrooms, boardrooms, nursing homes and small to mid-sized meeting rooms.
It enhances an organization’s existing investments in PC’s, enabling them to function like TTY’s. The audiometric patterns from the pure tone audiometry were variable with mild to profound hearing losses.
Support for a viral theory is the antecedent history of a viral upper respiratory infection and epidemic of viral diseases, such as parainfluenza, mumps, varicella, rubeola, and adenovirus infections.
Despite restoration of the cochlea blood flow, loss of endocochlear potentials may be irreversible after 30 minutes (4).
The patients, included in our study, did not have in their history any of these well-established courses or mentioned upper diseases. The entire examined group had tinnitus, which preceded the hearing loss by several hours with usually a roaring quality. Patients treated by the same course of corticosteroids and vasodilators and in addition immune-modulator – Isoprinosine – 3g per day (3x2 tabl.) for a period of 5 days. Histological analyses of temporal bones from patients who suffered from sudden sensorineural hearing loss displayed atrophy of the organ of Corti, stria vascularis and tectorial membrane. Hearing recovery in profound losses tends to occur in the low tones, which correlates with involvement at the apex of the cochlea rather than the basal end. Etiology of the sudden sensorineural hearing loss includes as well viral, vascular and viral-vascular combination. The arterial supply to the cochlea is such that the basal turn is fed first by the main cochlear artery with the cochlear apex fed last. Patients in our study reported antecedent history of upper respiratory infection within a month or less of onset of the hearing loss. Haemaglutination and slaging of blood may occur when virus particles attach to erythrocytes.
The findings in animal models of hearing loss of vascular origin prove extensive cochlear fibrosis and ossification. The viruses of mumps, measles, herpes simplex, herpes zoster, adenoviruses and influenza deserve particular attention in view of their clearly demonstrated etiologic role in sudden sensineural hearing loss. In the histological findings the organ of Corti was absent throughout the cochlea; the stria vascularis was atrophic throughout. The spiral ganglion cells were considerably decreased in the basal turn and somewhat decreased in the apical turn. Patients with measurable speech discrimination scores on presentation uniformly improved with treatment, even if their pure tone-average was profound. The cutaneus lesions associated with herpes zoster infections make this form of viral neurinitis and ganglionitis relatively easy to diagnose clinically and to relate etiologically the sudden sensorineural loss to the virus (6).
Presence of vertigo is associated with more severe losses and represents a greater insult to the labyrinth and those patients recover worse. The patients with vertigo passed observation for nystagmus, static and kinetic tests, posturography and ENG. The vascular endothelium is invaded and inclusion bodies may be seen in the endothelial cells in viral diseases. Application of combination of steroid, vasodilator and immunostimulater significantly improves the recovery outcomes in cases of sudden sensorineural hearing loss. There is, however, overall hyperemia at the site of inflammation and total effective blood flow may not be altered.
Infiltration of lymphocytes, plasma cells, macrophages and polymorphonuclear leukocytes occurs.
Necrosis of neuroepithelium may occur and is indicated by hyperchromatism, fragmentation and lysis of nuclei (5). The most common route of access of viral particles to the inner ear is a viremia in the early phase of viral illness in which virions are deposited within the membranous cochlea. Isoprinosine was used to support the mechanism of immune answer to the foreign agent – the virions and to reduce the damage of the cochlea structures. Medications like Acyclovir may be unhelpful when the cause is a virus that is not in the herpes family, that’s why Isoprinosine is favored. The corticosteroids, as well, have an anti-inflammatory effect on the organ of Corti and the microvasculature.



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