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This year marks a critical turning point in our understanding of the impact of neurodegenerative conditions. Two important studies have brought long needed attention to the critically important impact that diseases like Alzheimer’s have not only in terms of their progressively increasing incidence, but with respect to the financial impact of these conditions as well.
In April, the New England Journal of Medicine published a report from the RAND corporation assessing the costs of dementia in the United States. But what is most impactful is not only the finding that we are expending up to $200 billion annually in the care of dementia patients, but when this figure is contextualized, it means that our annual costs in dealing with dementia are twice that expended for heart disease and almost triple what is allocated for the care of cancer patients.
Professor Colin Prichard, writing the journal Public Health revealed that between 1979 and 2010, in the 10 biggest Western countries, there was a dramatic increase in deaths related to neurological disease. Healthcare professionals as well as individuals with elevated blood sugar are familiar with a simple blood test, hemoglobin A1c. Even fasting blood sugar is a powerful predictor of brain atrophy with studies demonstrating similar findings of progressive atrophy of the hippocampus in individuals with even mild elevations of blood sugar. This information is fundamentally empowering as we can absolutely impact blood sugar by making simple dietary choices.
Protein glycation, the connection of elevated blood sugar to protein, is a powerful leverage point that can be targeted to reduce both the production of inflammatory mediators as well as mediators of oxidative stress. Spread the Health by forwarding this article to your friends and family, and sharing on Facebook.
This entry was posted in eating, mind & brain and tagged alzheimer’s, alzheimer’s prevention, blood sugar, brain health, cancer, carbohydrate, dementia, Dr. Facebook Twitter Google+ LinkedInWe have created a collection of powerful self development picture quotes to remind you of your true power and potential that is deep inside of you and every other person on this planet. These are colourful quotes, quotes that you can set as your wallpaper on your cellphone, tablet or even tile on your own computer as an empowering reminder of the great skills, beliefs and abilities that we can harness at anytime to reach our goals and dreams.
I'm proud to say through my podcast and through this website we have impacted over 60 million lives in the last 4 and a half years.
The American Journal of Clinical Nutrition published one of the first studies to support green tea’s role in memory maintenance back in 2006. This curry component is a natural inflammation-fighting powerhouse, so it’s a staple supplement for any arthritis sufferer trying to get the jump on joint pain without dangerous drugs.

At least, that’s what researchers discovered in a 2004 study published in the Journal of Neurology, Neurosurgery and Psychiatry. Even after adjusting for all the major risk factors linked to Alzheimer’s disease, subjects with the lowest intake of niacin (just over 12 mg per day) were 80 percent more likely to be diagnosed with the disease. Ultimately, subjects with high niacin intake suffered from cognitive decline half as often—a staggering benefit from a deceptively simple B vitamin.
But L-carnitine’s closely related cousin acetyl-L-carnitine boasts a very different profile of perks.
Later trials delivered mixed results with acetyl-L-carnitine supplementation in Alzheimer’s patients.
Truth is, people have been relying on Ginkgo biloba to keep their minds sharp for quite a while now. Their meta-analysis looked at nine different trials, ranging from 12 weeks to one year in length, and featuring over 2,000 patients with multiple forms of dementia.
Results showed that subjects taking ginkgo fared better in cognition assessments than patients taking placebo. The report revealed that the prevalence of dementia in the US population over seven years of age stands at an incredible 14.7% with a yearly cost, per person, attributable to dementia ranging between $42,000-$56,000. The United States was the leader in this increase, with deaths from neurological disease increasing by 66% in men and an astounding 92% in women during this time period. The two cornerstone players in the pathogenesis of this disease are inflammation and free radical mediated stress, the action of free radicals which are damaging chemicals created during the normal course of metabolism.
A diet profoundly reduced in carbohydrate content focuses on addressing the fire of inflammation and free radical mediated stress that underlies neurodegeneration.
David Perlmutter, exercise dementia risk, free radicals, grain book, grain brain, heart disease, inflammation, Mayo Clinic, metabolism, neurogenesis: how to change your brain, new england journal of medicine, nutrition, oxidative stress, prevent dementia, stress on September 12, 2013 by pilladvised. I love connecting with people who have a passion for Entrepreneurship, Self Development & Achieving Success. Researchers compared the green tea intake and cognitive function of over 1,000 elderly Japanese subjects.
Curcumin prevents brain cell death and helps to balance critical mood-balancing neurotransmitters, too.

You might know this B vitamin best as a critical form of cardiovascular protection—responsible for keeping cholesterol in check and fending off heart disease and diabetes.
And, more specifically, its role in boosting physical performance and weight loss, while tackling serious issues like angina and heart failure. And one big reason for this is its ability to maximize circulation and boost blood flow throughout your body.
So in 2010, one team of researchers set out to address the ongoing controversy over this botanical’s effectiveness head on. If you want to boost mental clarity, improve memory and hopefully prevent Alzheimer’s disease, consider taking one, two or more of the brain boosters listed here. A1c is a marker of glycation of protein (hemoglobin) and as such is a direct marker of the degree of inflammation and free radical activity in the body, and more importantly, in the brain. One of the key messages of my new book Grain Brain is the fundamental tenant that returning to a diet that has characterized our nutritional program for more than 99% of our existence on this planet makes absolute sense, especially as it relates to preserving and enhancing brain function.
Perlmutter is the author of bestselling books including Power Up Your Brain: The Neuroscience of Enlightenment and The Better Brain Book . He serves as medical director of the Perlmutter Health Center in Florida and is an adjunct instructor at the Institute for Functional Medicine. I started this website with the intention of educating and inspiring likeminded people to always strive for success no matter what their circumstances.
I wouldn’t mind producing a post or elaborating on some of the subjects you write about here. And dietary data and cognitive evaluations taken at the end of the study revealed a dramatic trend.
Prichard stated, “This is in sharp contrast to the major reductions in risk of death from all other causes. Research appearing in the journal Neurology has demonstrated a perfectly linear relationship between blood levels of A1c and annual shrinkage of the brain’s memory center, the hippocampus.

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