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DESCRIPTION: While some earlier scholars would have labeled these maps as a€?the epitome of medieval European cartographya€?, due to the very ecclesiastical form and content, they were, indeed, an exception in this perioda€™s mapmaking.
In his recent book, Body-Worlds, Opinicus de Canistris and the Medieval Cartographic Imagination, Karl Whittington writes that on the 31st of March, 1334, this Italian priest named Opinicus de Canistris fell sick.
As mentioned above, Opicinusa€™ drawings survive in two manuscripts, both kept in the Vatican Library in Rome. There is no way of knowing how many other drawings Opicinus completed, and certainly no reason to believe that all or even a majority of his works have survived.
Victoria Morsea€™s 1996 doctoral dissertation for the first time performed a large-scale study in order to demonstrate the logic of Opicinusa€™ works.
It was not unusual during the later Middle Ages to bring together the body and the earth in pictorial representations.
The relationship on the page between texts, diagrams, and pictures throughout Opicinusa€™ work is an especially important issue. According to Whittington the captions on most of the drawings seem to interact with them in the following way: Opicinus created the visual material first, usually to address a particular theological question or theme.
The elaborate, complex, and beautiful drawings that Opicinus created in the years following his illness and vision are the subject of this monograph. What we see, then, is an embodied map a€” a picture of the eartha€™s surface that is also a depiction of human bodies. Opicinusa€™ beliefs and hypotheses about the earthly, the heavenly, and the human are encoded in the very structures of his drawings. Over half of Opicinusa€™ 80 drawings in the Vaticanus and Palatinus manuscripts include at least part of a portolan chart. Opicinusa€™ body-maps are far more complicated than any of the examples above, and the question of what they mean is more difficult to answer.
In a number of drawings, Opicinus used the most basic form of the body-worlds - presumably the one that he describes having received in his 1334 vision.
As in all of Opicinusa€™ drawings of the body-worlds, each figure takes on a specific identity, though in this example these identities are complex.
It seems most likely that the figure depicts a sort of hybrid a€” a personification of Christianity, with Christ at its head and its heart, surrounded by elements of the cosmic order. Its chest is bare (we can see the cloak falling away from the shoulder on the northern coast of France), but the lower roundel covers the place where a breast is often revealed in Opicinusa€™ female European figures. In three folios near the end of the Vaticanus manuscript, Opicinusa€™ cartographic drawings add one more layer of meaning on top of the basic arrangement outlined above: he superimposes a gridded local map of Pavia, his hometown, on top of a single portolan chart.
According to Whittington the precise placement and scale of the two maps is certainly not accidental; the maps have been placed in a precise relation to one another in order to create and explain correspondences between them. In contrast to this relatively simple correspondence, another caption shows how complicated his spatial interpretations could become. As a final word on this drawing, I want to return to one more visual feature: the form of the local city grid. In the two previous examples, Opicinus constructed a drawing using only one portolan chart; on fol. This doubling and mirroring of the portolan chart served a specific purpose: as Victoria Morse has argued, it allowed Opicinus to contrast the world as it was seen and known with the possibility of an alternate world converted to a state of grace. Each of the four land-figures bears an emblem on its chest a€” these signify the intention or motivation of each character.
On the bottom half of the page, however, similar captions placed on the white chart actually point to cities on that chart, rather than on the one below. Even after all of the figures in the drawing have been identified, its meaning remains elusive. There is one caption on the page that offers a tantalizing comment on its form and content. This quoted caption outlines the general principle that Opicinus follows in these drawings that employ mirroring or correspondence a€” that the multiplied forms are generators of multiple truths and realities.
Many Vaticanus drawings contain more explicit imagery of birth and reproduction; metaphors of birth and rebirth seem to have been one of Opicinusa€™ primary ways of expressing the spiritual transformation that he underwent following his illness of 1334.
The interest in the local ramifications of the pregnancy of the European figure is explored even more closely in two drawings in which Europe is actually pregnant with a tiny map a€” fols. DESCRIPTION: A good example of Protestant theologian Heinrich Buntinga€™s Europa, Europe as a Queen. It is a form of guided meditation where a person is gently led into what can simply be described as a very vivid daydream. The guide will tell a story and you will, by way of your imagination, follow along and picture yourself in that situation. When you are in a profoundly relaxed state, your mind is not able to differentiate between what is real and what is imaginary. Research with elite athletes has shown their muscles produce micro-movements in response to visualizing shooting a free throw in basketball. During guided meditation, the pictures painted in your imagination became very vivid and your mind experiences it as real. The deep relaxation created by a guided meditation script can lower your breathing and pulse rate, lower blood pressure and trigger the release of the feel good endorphins which can stimulate your own natural healing powers. If you imagine yourself enjoying a pampering spa bath with the water soothing away the stresses of your day, your muscles will relax as if it was really happening and the benefits you will experience will be real and measurable.
Using a guide in the form of a person, cd and mp3 allows you to lay back and just follow along and reap the benefits.
Relaxation and stress reduction can easily be achieved by stepping away from our daily stress filled lives for 15 minutes of meditation to ensure a calm mind. Spiritual development and growth takes place in moments of silence, inner peace, centeredness and reflection.
Effortless detachment from daily irritations will become easier over time and help you to keep things in perspective and to keep things insignificant inconsequential.
Find the source of happiness by realizing through meditation that inner peace is the true source of well being and that outer circumstance is of little consequence. Feel the warmth soaking into every muscle of your body, every nerve and every cell warm and relaxed…letting go, deeply and completely relaxed. Now imagine you can also feel the healing warmth of the sun healing relaxing and soothing you. Now imagine your whole body filling with light, clearing out all stress and fatigue and filling you with sunshine and vitality. While the 1950s saw the emergence of a few meditation pioneers such as Alan Watts, who only published his bestseller Psychology East and West in 1961, until the early 1960s, meditation in the West continued to remain largely the domain of spiritual seekers. Most meditation was being taught and practised within the context of either a Hindu yogic, Sufi, Buddhist or Taoist framework.
Meanwhile, as an unexpected and positive side effect of what was otherwise a tragedy of epic proportions, the communists invaded Asia and a wave of highly realised spiritual refugees fled persecution and escaped to the West. Beginning as a trickle in the 1960s and expanding into full flow in the seventies, innovative doctors and psychologists began to realise that meditation had specific therapeutic applications.
Up until this time the health of the mind was regarded in most medical circles to be quite unrelated to the health of the body. This was in the days before the development of advanced EEGs, functional MRIs, PET scans and other technically sophisticated techniques which in more recent times have allowed for empirical examination of the brain’s anatomy and function even while it operates. It is not surprising then that up until the 1970s very little academic research was being published on mind– body medicine in general or meditation specifically. The first significant book focusing on meditation as a therapy would appear to be Dr Ainslie Meares’ Relief Without Drugs.
Then in 1978 Carl Simonton and Stephanie Matthews published Getting Well Again, which broke more new ground as it applied Stephanie’s training as a performance psychologist to enhance Carl’s work as a radiation-oncologist.
If you believe that your quality of life depends on your quality of mind and you would like to maintain a regular meditation practice to promote your physical, mental, emotional or spiritually wellbeing, then our mind training program MindBody Mastery is for you. Homeopathic individualized medicines versus fluoxetine for moderate to severe depression: double-blind, randomized non-inferiority trial. Opicinus was a minor functionary and scribe at the papal court, which had moved to Avignon some thirty years earlier, and luckily for us he kept a kind of day-book that still survives.
Numerous scholars such as Camille, Kris and Salomon point to Opicinusa€™ a€?frequenta€? self-representation in the drawings.
Medieval mappaemundi often organized the land-forms of the earth around the shape of a crucifix (sometimes even a cruciform body), medieval astrological drawings commonly showed human figures at the center of cosmic and planetary networks, and the concepts of macrocosm and microcosm had been fully developed for a millennium.
It is possible, and productive, to partially separate Opicinusa€™ texts from his diagrams and pictures, especially those that represent his body-worlds vision. Opicinusa€™ works present a conundrum when it comes to audience and reception, since there is no textual or visual evidence that anyone ever actually saw the drawings.
Their unusual forms complicate our most basic assumptions about what and how medieval artists could represent. These structures form the core of the drawingsa€™ disorientation and strangeness a€” maps are piled on top of other maps, sometimes transparent and sometimes opaque, in a seemingly endless play of permeability and superimposition.
Some drawings contain one chart, others up to four; sometimes the continents and seas are embodied, while other times they are left plain. His drawings are so diverse and disorienting that generalizations about their design or meaning are difficult and often misleading. These drawings depict a single Africa and a single Europe, separated by the Mediterranean Sea.
The figure of Africa appears to be a woman; she is labeled Babilon maledicta [cursed Babylon] by the small caption above her forehead.
Captions suggest various identities: Christ, Opicinus, and a female personification of prudence are all indicated.
The face is smooth and beardless (many male figures in Opicinusa€™ work wear beards), and has long, flowing hair.
According to Whittington it is mainly a confrontation between two figures: a figure of Babylon (probably representing Islam) and a figure of Christianity.
This interplay between the local and the global is not unusual within Opicinusa€™ texts and captions on other drawings, which often comment on the everyday world of his youth and family (we must remember that he made these drawings in Avignon, not Pavia), but the specific visual alignment of parts of Pavia with parts of the Mediterranean region is unique in these three drawings. In the bottom right corner of the page is a caption that reads, a€?Just as the islands of purgatory pay a tax to the Roman Church, so too the Chapel of St. Opicinus seems to say that when any two maps are placed in relation to each other, if they are true empirical representations of Goda€™s created earth, one will find correspondences between them. One interprets the significance of the placement of Opicinusa€™ home parish district, around the Chapel of Saint Mary, delineated with a red outline near Tunisia and Sicily on the lower map. 84v each part of Opicinusa€™ hometown is given multiple interpretations, usually based on its placement on the portolan chart, but other times simply based on etymological connections, family stories, dreams, or coincidence.
Certainly the drawing contains multiple levels of reality: it is an allegorical depiction of three body-world characters in contact and dialogue, a depiction of the structural connections between local and regional realities, and a series of interpretive musings about the significance of these connections for Opicinusa€™ own life and family. As the reader may already have noticed, this grid strongly evokes the rhumb-line grids that were placed over contemporary portolan charts.
61r he uses the skeletons of two portolan charts of the Mediterranean region, which have been rotated and overlapped to form one image. 61r, parts of each of the charts remain intact, while others are distorted or hidden by the overlapping forms. In this particular example, the map shows the natural world at the bottom and the spiritual world at the top: labels on the drawing indicate that Affrica naturalis ypocrita and Europa naturalis occupy the continents of the smaller chart while Affrica spiritualis and Europa spiritualis talk to each other in the larger chart above. Europa naturalis bears a tarasque (a river demon from the Rhone) and Europa spiritualis contains an image of Christ showing his wounds, his side-wound situated suggestively close to Avignon, where Opicinus was living when he made the drawing. The message itself is simple enough: one must abandon the external senses that lead to sin in order to follow the internal senses to redemption.
58r of the Vaticanus Opicinus combines four small embodied portolan charts to create juxtapositions between the four seasons, the four cardinal directions, and the four states of the soul.
82r, we see many of the principles and techniques of the other drawings pushed to the limits of recognition and interpretability.
On its surface lie two complete portolan outlines that retain the white color of the paper. On the upper half of the page, the brown labels all point out the location of cities on the colored chart, even though all lie on the space of the white chart; they indicate the continued presence of the map below, even when it is obscured by the upper chart. At the precise center of the drawing, a cruciform shape is formed by the two mirrored shapes of Asia Minor and the Holy Land; Asia Minor forms the two arms, and the land below forms the body of a cruciform vestment. While other drawings seem designed to convey a single allegory or a primary confrontation between figures (which are often reinforced by the particular cartographic forms that Opicinus chose for the drawing), this drawing resists this type of analysis. According to the letter, this is a heretical position, since one species cannot be transformed into another.
84v, there are several depictions (or suggestions) of male genitalia in the Vaticanus manuscript, each of which is unique. 1350), a Pavian who worked at the papal court in Avignon, drew a series of imaginative maps, while acknowledging in a text written between 1334 and 1338 his use of nautical charts.
During a typical session a person will be lying down or sit comfortably with their eyes closed.
Some studies have shown that visualizing doing this is as effective as actually practicing it!
If the guided imagery scripts used are relaxing, healing and positive, your mind and body will experience relaxation, healing and positivity.
Healthier thought management can lead to increased inner strength, balance, clarity and personal empowerment. It’s warmth is melting away any tension, any aches and pains and unnecessary thoughts and feelings. The Beatles went to India, met the Maharishi and brought Transcendental Meditation (TM) back to the West. While His Holiness the Dalai Lama is the best known of these, many other luminaries suddenly became directly available to Western audiences. Documenting the advent of meditation as a therapy, therefore, begins with popular books on the subject. First published in 1967 in the United Kingdom, it appeared in fairly rapid succession in the United States and in Meares’ home country of Australia. The psychologist Larry LeShan had spent the 1960s delving into parapsychology and went on to become a founding pioneer in psycho-oncology, applying his psychotherapy training to the betterment of people affected by cancer. Herbert Benson, a cardiologist and convert to TM, published his scientifically based, runaway bestseller The Relaxation Response.
Carl and Stephanie focused on teaching their cancer patients imagery techniques to complement and facilitate radiotherapy treatment.
Ubiratan Cardinalli Adler, UNIFESP (Federal University of SA?o Paulo, Brazil), Av Rouxinol, 1041 cj. In a passage that describes what sounds like a stroke, Opicinus details how his body slowly became paralyzed; he temporarily lost his ability to speak, and much of his memory. Opicinus almost always dated the Vaticanus drawings, which were composed between June and November of 1337.
The passage describes a visionary experience: through oculus meis interioribus, Opicinus is granted a new view of the earth, one in which the land and the sea take on human attributes.
Most examples, however, lie in the realm of the theoretical, the academic, or the theological.
A significant problem with many previous studies of Opicinusa€™ drawings is that they take a few lines of text, from folios of the Palatinus, or from distant pages of text in the Vaticanus, and use them to a€?explaina€? the content of Opicinusa€™ strangest imagery. The captions (and some of the texts), then, are often the evidence of Opicinusa€™ self-analysis a€” he uses himself as a case study, personalizing the drawings through the text. Simply put, we do not know if they were ever viewed as more than a curiosity by those who encountered them. Visual parallels to these drawings certainly exist: body-maps have been produced in numerous periods, including such famous examples as the Ebstorf Map (#224, Book II, a medieval world map that placed Christa€™s body in the corners of the earth), the Leo Belgicus (a map of the Netherlands and Belgium formed into the shape of a lion, the earliest example of which dates from 1583), or the Europa Regina, a depiction of Europe as a royal female (see below). In these drawings, Opicinus was not trying to express a single concept or doctrine, but rather to visualize the possibilities raised by an entire new way of looking at the world, based on what he had seen during his visionary experience of 1334. The varied formats of these diagrams cannot be taken for granted a€” their arrangements form a crucial and underexplored aspect of their meaning. But looking at them as a group, perhaps the first thing one notices is that the map itself is incredibly accurate. The drawings in this first a€?categorya€? are not all alike, and there is no evidence that Opicinus thought of them as a group, but finding language to describe and categorize their forms is a critical first step in their interpretation. This folio includes a cartographic picture in the upper two-thirds of the page, and text at the bottom. She is a rare example of a figure with a distinct racial identity: Opicinus darkened her skin with a grey-brown wash, in a clear reference to an African or Middle-Eastern skin tone.
One could even identify Europe in this drawing as a kind of conglomerate figure of Christianity. The strongest indicator that the figure is female is the small child lying over Lombardy a€” the area always associated with the womb of the European figure. The simplicity of this contrast stands out despite the extensive texts and interpretations written around it.
Binary themes in similar drawings include a contrast between the mouth of hell and the temple of the Lord (fol. Opicinus played with this arrangement differently in each of the three drawings, changing the scales and position of the two maps, presumably seeking different correspondences. On the page we see the body-worlds with which we are now familiar: here, a female Europe confronts a female Africa, and the Mediterranean devil lies between them, his head to the east.
84r, in which the scale of the portolan chart is completely different (much smaller in comparison to the grid of Pavia); here, Opicinus identifies different correspondences and comes to different conclusions as a result of the change in scale. Yet the drawing is all about experimentation, layering, and play; to claim that creating or interpreting a drawing like this is a burden or struggle may be a modern misperception. But Opicinus piles on meanings, multiplies forms, and plays with realities seemingly as a form of experimentation. The grid may offer a clue to Opicinusa€™ working process, or the way he was inspired to create these drawings. Each of the two charts is rendered in a different scale, with a larger one oriented toward the top of the page and a smaller one pointed toward the bottom. On each map, the western Mediterranean retains its integrity a€” France, Spain, and the northwestern coast of Africa are clearly visible both at the top and the bottom of the page. In the Italian peninsula of the upper map, for example, which is overlapped by the eastern Mediterranean of the lower map, we see the word Roma written over the sea (on the sea-mana€™s forehead), signaling where the city would have been on the map below. Both figures of the a€?natural worlda€? are male (a bearded, older figure in Europe and a tonsured monk in Africa), while both of the a€?spirituala€? figures are female (Africa is a robed nun and Europe is a younger woman with long, flowing hair).
The question, just as in the previous examples, is how its meaning is changed, activated, complicated, or simplified by its construction within the doubled and overlapped forms of the portolan charts.
Within the drawing, small lines suggest points of correspondence between elements in each of the four quadrants. The three previous drawings were characteristic of a particular type; in contrast, this drawing is unique in Opicinusa€™ oeuvre. At the top of the page are two labels for Europe and Africa: Europe is the aduena rector novus, the strange new priest, and Africa is the parrochia aliena, the parish of another.
This is labeled in a caption on the right side of the page, which reads a€?behold the vestment of the Church soaked in blood.a€? Opicinus accentuated the form of the vestment by adding a small cutout for the neck.
The longer captions on this folio do not always contain a single focus, and many make no comment at all on the drawing. But spiritually there is truth in this mirror [i.e., in this drawing], since no heresy, fiction or allegory can be found that in this mirror does not give birth, at least in part, to a certain truth? Here, Opicinus seems to say that men do not transition literally into angels of light or darkness a€” the figures of the priest and parish at the top of the page do not actually become the figures at the bottom of the page. Even as Opicinusa€™ drawings make use of the natural world and empirical science, the arrangement of their forms expresses the detachment from reality that characterizes a dream. At first, we would not identify these as genitalia a€” they are simply two small, robed bodies that stand within the genital region of the European body.
Four of these drawings depict the body-worlds, and the reproduction always takes place within the body of the European figure. In each of these drawings, Opicinus drew a small copy of the body-worlds over the area of Lombardy, even extending it slightly into the sea near Genoa.
Many people prefer this type of meditation instead of using regular meditation techniques that requires concentration and discipline. Psychedelic drugs burst out of the experimental laboratories of psychiatrists and the CIA, and flooded the streets. This general lack of professional interest in these subjects was exacerbated by the fact that the philosophy and techniques of analytical Western science seem far removed from the apparently mystical and mysterious world of the mind and meditation. His book How to Meditate, intended for a general audience, was published in 1974 and became a standard reference for many years. Benson advocated a more secular version of TM, detailing a simple mantra-based meditation technique. They reported positive results and their research findings rapidly opened the doors to developments in the study and practice of the therapeutic use of imagery. He returned to these folios frequently in the years that followed a€” many include changes, graphic additions, or new captions, which he dated individually (we find dates from the years 1338-1341, especially). Morsea€™s other crucial innovation, in addition to asserting the rational and intentional basis of Opicinusa€™ thought, was to place the Vaticanus manuscript at the heart of her research. Salomon and others characterize the themes of the Vaticanus manuscript as just an extension of those in the Palatinus.
The shapes of Europe, Africa, and the Mediterranean Sea each contain (or form) a human figure; these are the forms that Whittington calls a€?body-worlds,a€? and they constitute Opicinusa€™ most original and perplexing contribution to 14th century visual culture. One of the things that makes Opicinusa€™ drawings so unusual is that they also incorporate a visual tradition that was practical, empirical, and scientific a€” medieval sea charts, usually called portolan charts. He often kept adding to the drawings over many years, including new details or textual explanations, and dating them to a specific day.
As mentioned above, it seems possible that the Vaticanus was never meant to be viewed by others; much of it is arranged chronologically (like a diary), rather than thematically, and the subject matter of the texts and images suggests a private function.
The meaning of such imagery obviously depends on context, but these diverse examples demonstrate how a land, country, or region has often been embodied within a human figure, to show the potential power of that space, or even the dominion of a figure over it. The images of Africa and Europe as human figures were the core of this experience, but the interpretation of the vision was left up to him. According to Whittington the formats of Opicinusa€™ body-world drawings can be grouped into four categories: (1) single portolan charts, (2) portolan charts overlapping with local maps, (3) multiple portolan charts overlapping with each other, and (4) multiple, mirrored portolan charts. The coastlines of the Mediterranean and the relative scale and position of the landforms are almost exactly the same as we know them to be today.
The figure appears to be bare-chested, although no breasts are visible (perhaps they are covered by her long hair).
But the label above the head of the figure seems to identify it as Opicinus assuming the identity of a€?the house of God.a€? Another caption in the Mediterranean Sea off the southern coast of France labels the figure as an Ymago Prudentie.
The fact that the face is labeled as Christa€™s would indicate on the surface that the figure is male. Yet beyond the basic characters and the captions, the drawinga€™s meaning is clearly activated or shifted by the placement of the two personifications within the geographical forms of the portolan chart; after all, it is not difficult to imagine a much simpler way to express this confrontation, using only pictures and no maps. The scene is full of interesting and surprisingly graphic details, many of them interpreted in the marginal texts. Such interpretations are, I think, meant as models; as Morse demonstrated, Opicinus hoped that the drawings could be used by others to probe their own consciences and personal histories. Many parts of it must have been intentionally humorous, such as the basket for collecting the sea-mana€™s excrement, the graphic sexual organs, the interpretation of the Europe womana€™s pearl earrings, or the depiction of the Africa womana€™s cloak as a green river.
Even when texts in the Vaticanus indicated the stressors in Opicinusa€™ life a€”spiritual, moral, legal a€” the drawings remain exploratory and even lighthearted. Without any words from him on the subject it is impossible to know where such an idea comes from, but perhaps the grids on the portolan chart(s) from which Opicinus was working reminded him of a gridded map of Pavia that he had seen, or perhaps even made. The mapsa€™ superimposition encourages the viewer to seek correlations between them, and Opicinus reinforces these correspondences by drawing actual lines and lines of text to connect various parts.

He grafts a spiritual system of correspondences and coordinations onto this new representation of the physical world, but specifically includes details that undermine both systems, seeking instead a negotiation between the two. The rota on the breast of Affrica naturalis shows the mental processes that lead to sin: thinking, imagining, deciding, and delighting in (cogitatio, ymaginatio, electio, delectatio) lead the sinner to consent to sin (consensus peccati). These can either connect the same geographical location between two separate maps (as in the line drawn between the two Carthages on the upper left map and the lower left map), or establish a point of contact between the same physiological parts of two body-worlds on the same map (as in the line drawn between the reproductive areas of the Europe-woman and the Africa-woman in the upper-right map). It contains four complete portolan charts, all the exact same size, placed in careful relation to one another through overlapping and mirroring. This is different from the numerous drawings in the previous category, in which the two charts overlapped one another; here, the two white charts on the surface of the page are both complete diagrams of the region, reflecting one another along an invisible horizontal line in the Holy Land and Asia Minor. The figures seem to present the encounter between a new priest and his new parish (a situation that Opicinus underwent several times in his early career). The role of this form in the drawing is ambiguous a€” its cruciform shape and its a€?soaking in blooda€? certainly evoke Christa€™s sacrifice, and its position at the heart of the drawing, precisely where the two white maps are mirrored, suggests that it may be significant in the transition between the two.
One caption on the left side of the page is a short rant about the mosquitoes that were bothering Opicinus while he made the drawing, while another, longer text at the lower left is an extended metaphorical description of the penis, describing how, like a heretic disobeying the Church, the penis disobeys the orders of the body. It is the caption that tells us something different; over their heads are written the words a€?matrixa€? and a€?virgaa€? a€” womb and penis.
Representing pregnancy and birth inside of Europe was a way for Opicinus to convey how both good and evil tendencies enter the world. Some researchers have convincingly explained this positioning of the tiny body-world figures as indicating a Caesarian birth; as Opicinus explains, the two figures are born through Genoa, the a€?forced porta€? in the stomach of the European figure, rather than through Venice, the a€?natural porta€? of the figurea€™s vaginal canal (Opicinus makes the pun about Venetian a€?canalsa€? several times).
The earliest depiction of Europe as a woman is believed to be by the 14th century Pavian cleric Opicinus de Canistris for the papal court, then at Avignon. Vietnam galvanised a generation, the counterculture flourished, and people were intent on expanding their minds. There is a need for large-scale longitudinal data on treatment utilization and outcomes, stress, emotion, and pain.
The dating of the Palatinus is more complicated a€” the large autobiographical calendar on fol. The Vaticanus was often mentioned by earlier authors, but had never been the object of extensive study, perhaps because its visual material is smaller and less elaborate than the large Palatinus folios. These and other claims are refuted by Whittington with a basic statistical analysis of the manuscriptsa€™ subject matter. Their enigmatic forms, expressions, and arrangements have the power to arrest the attention of modern viewers, reversing expectations about what sorts of imagery were possible in the early 14th century.
The a€?world,a€? in Opicinusa€™ drawings, is always represented using these charts; they form the drawingsa€™ structural basis and frame their meanings.
Still, crucially, this does not make the drawings, in their inception, a€?abouta€? Opicinus.
The large size of the Palatinus folios suggests a more public function, given their physical similarity to large medieval wall maps and portolan charts.
Here one sees before a map of the Mediterranean world a€” Europe, North Africa, Anatolia and part of the Near East are left the white color of the paper, and the seas around them are tinted with a reddish-brown wash. The incredibly diverse drawings that he created in the years that followed were his way of exploring the meaning of this vision and experimenting with different strategies for representing its shape and scope, searching for the arrangements and combinations that would lead him to the deepest meaning. Opicinusa€™ maps were based on the most modern and technically accomplished cartography of his day a€” marinersa€™ sea-charts, which we call portolan charts. Several folios depict only the western portion of the standard Mediterranean portolan chart, limiting their view to the area between Gibraltar and the boot of Italy. The geographic range of the depicted portolan outline is narrow - we see Gibraltar, Tunisia, France, Spain, and Italy, but none of the eastern Mediterranean, which is cut off by the drawinga€™s lower edge. Little is visible of her lower body, but she wears some kind of cloth wrapped around her waist. However, the most prominent indicator of the figurea€™s identity is the large rota around the face in the Iberian peninsula, which seems to label the figure as Christ. The drawing thus suggests a combination of male and female elements: a pregnant female personification of Christendom, with Christ at the head and heart. In this first example, where the contrast between the two figures is simple and direct, we can more easily explore two ways that the form of the drawing a€” its geographical frame a€”may change the meaning of these figures. For example, the Mediterranean figure appears to have two sexual organs a€” one massive penis that seems to be ejaculating onto the southern coast of Spain, and another that he clutches in his fist (presumably in an act of masturbation) near Venice. 84v, numerous captions explore the moral, theological, quotidian, and incidental correspondences created by the overlay of the city grid on the portolan chart. In addition, the monastery with which they were both associated fell near Rome on the portolan chart.
The revelation and the experiment were meant to be used by anyone a€” Opicinus is using himself as a test case, taking examples from his own life, family history, and childhood, and using them to interpret the correspondence between the two charts. These are all examples of Akbaria€™s horizontal allegory, or of allegory as a primarily interpretive act; Opicinus creates the structure (which may or may not have an intrinsic meaning a€” in this case, it seems not to), but the primary work is put into interpretation, play, and the creative exploration of his visual construction. Opicinus created, an over-determined world because of its opportunities and flexibility, not to build a burdensome system that would collapse on top of him. This basic format is repeated on at least eight other pages in the Vaticanus; again, there are variations in the size and placement of the two maps, but all of these examples include two portolan charts that are laid on top of one another. In the smaller, lower image, the negative space of the chart a€” the sea a€” is tinted with a light brown wash, delineating the body of the so-called a€?Mediterranean Man,a€? often labeled a€?Lucifera€? His head and beard occupy the eastern Mediterranean (his ear tucked against the Nile delta and curving beard shaping the coast of the Anatolian peninsula), his arms gesture near Italy (one fist plunging violently east of Italy, forming the Adriatic), and his feet poke out near Gibraltar, between the faces of Europe and Africa.
On this page he connects the two representations of the Adriatic with a diagonal line that slices through the center of the image, running from Venice on one chart to Venice on the other. Morse also points out that different renderings of the sea in the two charts likely correspond to their content; the embodied a€?devil seaa€? lies between the natural worlds, while the a€?spiritual seaa€? is left empty, perhaps to indicate its purity.
Small lines connect the first four concepts to the eyes, ears, nose, and mouth of the Africa-figure, indicating the complicity of the exterior senses in this pathway to sin. 74v how Opicinus, by framing his allegories within the portolan charts, solidified their meaning into measured form, aligning the worlda€™s shapes with the truths and figures they revealed. The meaning of such lines remains ambiguous, but they do suggest points of contact and interconnection between elements that are otherwise set in opposition to one another.
All four of these portolan charts are embodied, creating eight distinct characters: four male figures of Europe, and four figures of Africa (two angels and two male figures). Rather than containing the figure of the diabolical sea, the spaces of the Mediterranean and Black Seas on these two charts are left as windows through which the viewer can see the other maps in the drawing.
The colored worlds below are not labeled, but the figures seem to be a precise mirror of those on top, in both gender and physical appearance. Opicinusa€™ statement about the generation of meaning seems to apply both to this drawing and to many others that depict multiple levels of reality (usually through multiple iterations of the body-worlds). 82r becomes overwhelming, Opicinus provides the viewer with visual cues to make sense of the drawinga€™s disorienting forms. This drawing contrasts two complete sets of body-worlds, one overlapping and partially obscuring the other, and two very different depictions of genitalia are found in the area around Venice on both depictions of Europe. In a passage early in the Vaticanus, Opicinus describes how the a€?diabolical seaa€? inseminates an already-pregnant Europe, splitting the child unnaturally into two figures a€” Europe and Africa.
Victoria Morse shows the way that Opicinus read meaning even into the precise position of these two tiny body-worlds over Lombardy below, determining which local cities fell under Africa and Europe.
Very quickly meditation in the West was popularised, and perhaps even stigmatised to a degree, as the domain of the hippies. The first 48 contain little visual material besides a few marginalia, while the second half of the book includes some text-only pages, some full-page drawings, and some smaller drawings with extensive text on or around them. 11r, which provides the most complete information about his life, ends with June 1336, suggesting that this drawing was finished by that date.
In contrast, Morse demonstrated that the Vaticanus holds the key to understanding Opicinusa€™ thought: its drawings are more intimate and revealing, and it contains over a hundred pages of text.
Portolan charts were modern, cutting-edge diagrammatic maps of the Mediterranean region, and Opicinusa€™ use of them transforms what would otherwise have been old-fashioned, theoretical, and primarily textual drawings into a completely new type of representation.
Interpreting the vision with relation to his own body and life was only one of the tactics that he used. The drawings in both manuscripts could have been preparatory studies for some larger-scale project or commission that was never carried out.
According to Whittington, to explain what the body-worlds a€?mean,a€? one must explore how and why Opicinus harnessed these maritime maps to a completely different purpose from that for which they were created.
Others include the entire range of the chart, from the Atlantic Ocean to the Black Sea and the Holy Land. Small captions and rotae are positioned at various points on the map; some of these are placed to comment specifically on a geographical feature, while others remark more generally on the drawing and its characters. A worm or snake emerges from an otherwise empty circle on her stomach, twisting along the North African coast, its mouth gnawing on the figurea€™s thumb near Carthage. Large red capital letters spell out C-R-I-S-T-U-S, with each letter also being the first letter of one of the seven gifts of the Holy Spirit. Opicinus uses the portolan chart to construct a binary system in which values can be opposed, and also to place these allegories or personifications within a space that is, in the broadest sense, real. On the southern coast of France, a basket-woven pattern is explained in a caption as a basket to catch the excrement of the sea-figure. For example, in a short passage in the upper left corner of the page, Opicinus mentions that the body of the sea-devil extends beyond the inner city wall of the Pavian map, which he interprets as a sign that malice and mischief are spread out in the city; beyond the old city walls. An over-determined world allowed him to make visible to himself and his potential readers the primary concerns, impulses, histories, and spaces of his world and his body in a way that led to potentially productive connections and revelations. In contrast, the sea of the larger top map is not embodied, and retains the color of the paper.
This line could help the viewer perceive the imagea€™s orientation, by providing a reference point for the location of the same city on each map at this crucial juncture at the center.
The sea-figure takes control of the pagea€™s center, superimposing his twisting body over the eastern half of the upper, spiritual chart a€” his a€?negativea€? space dominates the positive space of the other chart.
In contrast, a caption on the rota for Affrica spiritualis points to the interior senses (sensus interiores) that indicate spiritual progress: meditation, contemplation, discernment, and rumination (meditatio, contemplatio, discretio, degustatio). They also establish that the body-worldsa€™ identities as both bodies and maps remain significant on their own; because connections rely on their status as both maps and bodies, one is not emphasized over the other.
This window or outline a€” the negative space of the upper drawing a€” provides a view onto a world of color. The mirror of any of his creations, which he acknowledges are fabrications (in the sense that they are imaginary and exploratory), will always contain some new level of meaning. The two red lines indicate the precise point where worlds are mirrored, and the differentiation in color a€” white, brown, and red a€” brings the forms of the body-worlds into a near-sculptural relief. In the overlapped body-worlds, which are tinted with red and brown wash, we see a small penis depicted inside the figure of Europe, just past the fist of the Mediterranean figure.
It must be acknowledged that both figures are shaped like small penises, but it is also true that in medieval anatomical texts the female genitalia are often described as an interiorized mirror image of a male penis, so perhaps we should not be surprised that the two are a€?personified,a€? if we want to use that term, in similar ways. According to Victoria Morse, Europea€™s pregnancy was also related to local political situations, visualizing the (sexual) corruption of Lombardy within an otherwise holy European body. She then contrasts this a€?violenta€? delivery of the figures with the small baby depicted on fol. In 1537 the Tirolese cartographer Johann Putsch celebrated the Hapsburg rule over Europe by presenting a placid a€?Europa Reginaa€? wearing Charles Va€™s Spain as a crown and Ferdinanda€™s Austria as a medal at her waist, representing the triumph of the Hapsburgs.
Randomized long-term trial of camel milk as an adjunct to insulin therapy in type-1 diabetes.
The representation and interpretation of this divine image of the earth would occupy much of the rest of his life.
Other dates in the manuscript are scarce; most scholars agree that the bulk of the drawings were completed between February 1335 and June 1336, with later additions stretching all the way to 1350. Opicinus was working during a crucial moment in the history of cartography, when numerous artists and mapmakers sought to combine old and new forms.
Most of the drawings suggest other interpretive avenues, through personifications, allegorical confrontations, or superimposition; one does not have to turn to Opicinusa€™ biography to explain them. It is also possible that these works were intended, like several of Opicinusa€™ earlier treatises, for the Pope. In this example, Europe is embodied as a man a€” his head occupies the Iberian Peninsula, his chest and stomach lie in France (where some kind of beast in the ocean tries to bite at his shoulder), his arm arches up through the lowlands and Germany, and his legs occupy the Italian peninsula and the Dalmatian coast. He used this technical, practical, scientific cartography to probe deeper into the nature of God and the created world. But all of the drawings in this category share a single feature: they include only one map, one level of cartographic reality on the page. The two figures that constitute, lie within, or coexist with Africa and Europe are classic examples of Opicinusa€™ body-worlds (the third figure that often appears in the Mediterranean is not included, in this particular drawing).
In two outer concentric rings Opicinus places the names of the seven planets and the days of the week.
Yet their placement within a map, particularly an empirical one which was actually used for travelling, emphasizes the tenuousness of such binary oppositions. Despite these and other details on the figures, the actual bodies seem less important to Opicinus in these three drawings; the commentary focuses more on the physical interplay and connections between the two overlapping maps.
It is not that he thinks that this image of the two maps placed in this particular arrangement is necessarily a€?correcta€? or a€?truea€? a€” on fol. 84v offers further evidence that Opicinus viewed the portolan charts as empirical representations. At the centre of the page the embodied eastern Mediterranean of the lower map (including the Black Sea) overlaps both the land and the sea of the upper map, so that its eastern half (part of Italy and all of Greece, Egypt, and Turkey) is obscured. Or, given the opposing genders of the two Europes in the maps, and the fact that the area at the top of the Adriatic was understood as the erogenous zone of the European body, the line could suggest a sexual point of contact a€” even intercourse a€” between the two figures. It is necessary first to describe and explain the drawinga€™s complex structure, before discussing its content in relation to several captions that surround it.
In the space below, the continents are shaded a brick red, while the seas are painted a soft brown-grey. The interpretive paradigm for this drawing must be one of experimentation; it is the only image in the manuscript with this particular arrangement of forms, and through it Opicinus only seems to have arrived at fragments of meaning. The small caption nearby simply reads Venetie [Venice] and without further explanation it is unclear whether the penis belongs to the European body, depicted lying back against his stomach, or whether he is somehow being penetrated by a small penis belonging to the sea-figure. Here, reproductive sexuality is a sign of corruption; elsewhere, as we will see, it is a marker of generative spirituality. 74v, which is positioned for a normal delivery through Venice, with its head down and its arms folded peacefully in prayer.
The queena€™s crown (Spain), orb (Sicily), and heart (Bohemia) from a triangle that directs the viewera€™s eye away from Eastern Europe toward the West. In over eighty surviving drawings, now kept in the Vatican Library and referred to by scholars as the Vaticanus and Palatinus manuscripts, he experimented with how he could uncover the meaning that he was sure God had planted in the vision he saw, in the hope that his drawings would help to renew the faith of all Christians. Far more drawings in the Vaticanus portray body-worlds (23), while few in the Palatinus do so (6).
This encounter between the scientific and the spiritual is best explored by looking at the structures that Opicinus used to create the drawings.
Another rota lies inside France, near the location that Opicinus usually associates with the a€?hearta€? of the Europe figure a€” Avignon. On a map you can literally sail by sea from one a€?placea€? or a€?bodya€? to the other a€” each place is accessible to the other.
Here, the grid structures the space of the local map, but also shapes the way we view the portolan below. It looks like a kind of symbolic twin to the spatio-indexical rhumb lines of the original portolan charts. 61r demonstrates that Opicinus was also aware of the dangers of aligning appearance with truth; appearances could just as easily deceive as reveal. The arrangement of these colored maps beneath the surface of the white ones is the most complicated aspect of the drawing. The angels are labeled angelus lucis and angelus tenebrarum a€” an angel of light and an angel of darkness. Given the penises in this region that we discussed above, this latter proposition is not without basis, but it seems more likely that it belongs to the European figure, since it is tinted the same color. Nearly all of the drawings in the Palatinus feature what Whittington calls an a€?overarching containing structurea€? a€” a geometrical framework that contains all of the drawinga€™s content. Her face is to the west, shown in profile as she seems to whisper into the ear of the European figure across the Straits of Gibraltar. She seems to speak directly into the ear of the European figure, depicted partly in profile and partly from the front. At the center of the roundel is a seated figure of Christ showing his wounds; around this are the names of seven episcopal seats, and the seven planets and their positions. In these simplest drawings, though, such a possibility is only hinted at; a much fuller manipulation of the metaphor of travel and movement between binaries, and indeed a subversion of the very concept of binary opposition, is found in Opicinusa€™ more complicated images, discussed below.
This grid, eight squares by ten, is oriented in the same way as the map below, with east at the top of the page (the street grid of Pavia was, and still is, slightly off-axis from the cardinal points because of its alignment with the river, which is reflected in its positioning at a slight angle on the page).
Opicinus just seems to be testing each possible arrangement on either side of the folio, turning it back and forth to see which parts of it align with things he believes to be true.
Any resident or visitor familiar with the city would recognize that the local map of Pavia was a measured, accurate representation, and the fundamental hypothesis of this image and its interpretation is that correspondences can be deduced through the alignment of one measured map with another. One complete map lies below the upper white map, and one complete map lies below the lower white map, but each is placed in a different relation to its chart above. The angel of light in the surface map whispers into the ear of the upper male Europe, labeled homo spiritualis, while the angel of darkness whispers to homo carnalis. 61v, where two tiny figures with the same labels hold between them a baby, its head positioned downward, pointing toward the area near Venice through which we presume it would be born.
Patients are recruited from web sites for patient advocacy and health enhancement programs. The danger of any study of Opicinus is that in seeking out the contexts in which one may understand Opicinusa€™ work as logical and coherent, one risks losing sight of what makes them so exceptional. But he also used this idea in order to create images unrivalled in their complexity and interpretive difficulty, multiplying maps and figures across the page in kaleidoscopic networks. The local grid is filled in with detail; the numerous small labels in brown indicate churches, city gates, bridges, and monasteries in Pavia, while the few red captions refer to cities or regions on the portolan below (here, like elsewhere, Opicinus uses color to clarify his content for the reader). Once again, a grid serves two functions, measuring the space of one reality and indicating the measurability of another. On the top half of the page, the tinted map below is a precise mirror image of the upper map, reflected from it along a red horizontal line that bisects the upper, white body-worlds.
The arrangement recalls nothing so much as the angel and devil of the human conscience that perch on the shoulders of cartoon figures in modern movies and comics, offering advice and urging the character towards good or bad decisions; in the drawing, the heads of the angels seem to rest directly on the shoulders of the figures below them.
Here, the two a€?personificationsa€? of the penis and the womb have produced a tiny child and are preparing it for birth. Later editions of Europe as a queen were issued by Sebastian Munster, Heinrich Bunting and Matthias Quad.
Therefore this long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an adjunct to insulin therapy in type 1 diabetic patients. This a€?manuscripta€? is a collection of 27 huge unbound parchment sheets, averaging about two by three feet, although some are significantly larger. This observation prompts the next a€” that the Palatinus drawings almost always include calendars (usually as part of the overarching containing structure), while few of the Vaticanus drawings do. Looking at the drawings as a whole, there can be no doubt that there are distinct threads running through them a€” themes, problems, and possibilities that Opicinus set out to explore. And just as the drawingsa€™ forms combine simplicity and complexity, their content also veers from the straightforward to the impenetrable. The relationship between these human figures and the landforms is, as is always the case in Opicinusa€™ drawings, very difficult to describe.
The huge green swath at the right of the page indicates the Ticino River, which is coextensive with the long veil or cloak worn by the Africa woman. The white body-worlds in the top layer always overlap the lower, colored ones, which are only visible in the negative space of the sea. These personificationsa€™ sexuality is normative and non-transgressive a€” male and female members come together inside of the female body. Methods: In this 2-year randomized clinical parallel design study, 24 patients with type 1 diabetes were enrolled and divided in 2 groups.
Depending on the individual viewera€™s perception, the figures can seem to be lying on top of the land, growing out of it, or somehow placed under it a€” as if the landforms are windows through which we are looking.
The green lines at the top and bottom of the page show the path of several Pavian canals, and the three concentric red boundaries drawn around the page indicate the city walls. The same system is repeated in the lower half of the drawing, except that the lower tinted map is reflected along a vertical line, also colored red. Group I (n=12) received usual care (ie, diet, exercise, and insulin), and group II (n=12) received 500 mL camel milk in addition to diet, exercise, and insulin. From these observations, Whittington generalizes some of the basic differences between the two manuscripts.
Most of all, however, these enigmatic forms seem to depict the earth and the bodies as coextensive, and of the same material a€” bodies made out of the earth. The two maps on the bottom half of the page are also mirror images of one another, but along a different axis. The Vaticanus seems to be more of a personal manuscript, perhaps never intended for a wider audience.
The more one looks at these body-worlds, the more one sees the human figures as figures a€” the stranger parts of their bodies, where the landforms do not align so easily with a normative human shape, become less and less noticeable. The two red axes are thus crucial to understanding the drawing: they must have been used to construct it and also intended to aid in its decoding. Its drawings are less structured and presentational, contain more sexual imagery, and include more personal themes, all of which we might associate with a private, rather than public function (although such distinctions were perhaps more fluid in 14th century Italy than they are today). Secondly, the drawings in the Vaticanus and Palatinus have very different structures; the Vaticanus uses the form of the portolan [nautical] chart to structure meaning and representations of bodies, while the Palatinus drawings use larger geometric, ecclesiastical, and temporal frames, which in turn often contain representations of the earth.
Finally, the Palatinus drawings contain a temporal, cyclical element (numerous calendars and representations of the zodiac) that the Vaticanus drawings usually lack.
Previous studies have found that between 30% and 60% of pediatric neurology patients have used CAM at some point in their lives.
Whereas, the effect of vitamin C on conventional photodynamic therapy (PDT) of tumor cells has been documented, the mechanism of vitamin C induced increase in tumor cell response to PDT is unclear. In this report we demonstrate the presence of vitamin C during photo-oxidation of MC540 significantly increases its apoptotic activity in tumor cells. Interestingly, we observed that the presence of vitamin C during photo-oxidation of MC540 only and not its addition to a prior photo-exposed mixture to MC540 is critical for its enhanced sensitivity. These findings provide impetus to the approach in developing ROS generating small molecule compounds with potent apoptosis inducing activity. These data could have implications in the use of vitamin C in photo-sensitizer-mediated reactions with the view to favorably tailoring the cancer cell milieu for efficient apoptotic execution.
Many patients are still not discussing their CAM use with their doctors and are using CAM alongside their conventional medicines, thereby increasing the likelihood for potential interactions. One limitation of this study is that our ability to determine between-site differences is limited by the difference in sample size. Electrodermal measures as clinical markers: Jing-point electrical impedance in adolescent women with chronic pelvic pain. Consequently, skin electrical measures at Jing points are commonly obtained and interpreted for diagnostic purposes. Denise Adams, University of Alberta, 1047 RTF Building, University of Alberta, Edmonton, AB, T6G 2E1, Canada. The objective of this study is to determine whether electrodermal measures at Jing-points are associated with clinical outcomes in adolescents with chronic pelvic pain in a randomized, sham-controlled acupuncture trial. Methods: We recruited 18 adolescent women aged 13 to 22 years of age suffering from chronic pelvic pain and laparoscopically diagnosed with Stage I-III endometriosis.
Using a Hibiki-7 device, normalized electrical impedance values were obtained at all 24 Jing-points for each treatment session.

Phase II: CAM research networks in Canada and the US will notify CAM providers of this study, so they may alert patients.
Left-right asymmetry and measures for statistical dispersion (standard deviation and Gini coefficient) of Jing-point impedance values were calculated. Parents or legal guardians may self-identify and reply on behalf of patients under 18 year of age if they meet the criteria for Phase I.
With a generalized estimating equation method, we evaluated the association between the electrodermal-derived measures and clinical outcomes while accounting for treatment designation and time. Phase III: The methods for phase II were utilized but CAM associations and training organizations were substituted for CAM research networks.
The majority of the cases involved the use of Traditional Chinese Medicine to improve quality of life. Preliminary analyses indicate that, over time, subjects in the active acupuncture arm were more likely to have reduced left-right asymmetry and statistical dispersion of Jing-point measures compared to subjects in the sham-control arm. Further analyses with multivariable models will be performed to assess whether this difference is statistically significant for each electrodermal measure.
The chiropractic care of children with otitis media: a systematic review of the literature utilizing whole systems research evaluation and meta-synthesis.
Joel Alcantara, International Chiropractic Pediatric Association, 327 N Middletown Rd, Media, PA 19063.
Key words were otitis media and related words (ie, acute otitis media, otitis media with effusion, ear infections, etc) AND chiropractic. A narrative review of the literature was performed and augmented with a meta-synthesis of the literature with a focus on chiropractic management and the application of a whole systems research (WSR) evaluation.
Results: Our systematic review revealed 20 articles consisting of 6 case reports, 5 case series, 1 retrospective cohort, 2 prospective cohorts, 2 reviews of the literature, 2 commentaries, 1 survey study and 1 prospective, parallel-group, observer-blinded, randomized feasibility study. Due to the lack of higher-level research design, a meta-analysis of the literature was not possible. This included the use of otoscopy and tympanogram to provide objective pretreatment and comparative outcome measures. Eighty-nine percent of respondents reported treating pediatric patients; patients under the age of 17 made up 12% of chiropractic and 20% of both naturopathic and osteopathic patients.
Activator, Gonstead, Toftness, Chiropractic Biophysics, and Diversified Techniques were utilized with an emphasis on the upper cervical spine (the C1 or C2 vertebral bodies). Approximately two-thirds of both osteopaths and naturopaths disagree or strongly disagree that immunizations are safe compared to one-third of chiropractors. One paper described utilization of cranial technique, 2 papers described a dietary intervention, and 2 papers utilized soft-tissue massage to augment spinal manipulative therapy. Fifteen studies were amenable to the WSR evaluation resulting in a score of 7.06 from a maximum of 11. The immunizations of most concern to the 3 professions included MMR, varicella, influenza, DPTP, and hepatitis. The most common reasons for concern were related to safety, including that vaccines may contain dangerous ingredients, may produce side effects, and may be linked to future problems such as neurological damage. Conclusion: This systematic review highlights the need for more higher-level research designs in addition to incorporating new methodologies (ie, whole systems research) reflective of the holistic and vitalistic clinical and theoretical framework of chiropractic.
The chiropractic care of children with enuresis: a systematic review of the literature utilizing whole systems research evaluation.
Significantly more naturopaths advised parents against vaccinations (27%), compared to 10% of chiropractors, and 12% of osteopaths (P=.0002). Joel Alcantara, International Chiropractic Pediatric Association, 327 North Middletown Rd, Media, PA 19063. There was no significant difference between groups for those advising parents in favor of vaccinations (15% C, 14% N, 6% O) (P=.1143). Key words were enuresis, nocturnal enuresis, bedwetting as well as related words AND chiropractic. A narrative review of the literature was performed and augmented with an evaluation using WSR evaluation. Results: Our systematic review revealed 7 articles meeting the eligibility criteria for review. Four of the 7 papers involve case reports describing the care of children aged 8 to 14 years with primary complaints of nocturnal enuresis. Spinal manipulative therapy involved the use of Toggle recoil, Sacro-Occipital Technique, Activator Methods, Gonstead Technique, and Diversified Technique to address primarily segmental dysfunctions in the lumbosacral spine. We conducted a systematic review to assess the nature and severity of adverse events associated with pediatric acupuncture.
A large prospective cohort study (N=171) demonstrated improvement in wet nights per week from baseline following 2 weeks of care. In a randomized clinical trial, within-group comparison of pretreatment and comparative rates of enuresis subjects demonstrated an improvement.
However, the study was fraught with research design issues such as randomization and biostatistics. Six of the 7 studies were amenable to WSR evaluation and resulted in a scoring of 7.33 from a maximum possible score of 11 points. One reviewer screened all articles, while the second reviewed all excluded articles to ensure that no article was inappropriately excluded. Full articles of potentially relevant references were retrieved and assessed by two independent reviewers.
The use of Whole Systems Research provides promise in contributing to evidence-based practice and reflects the holistic and vitalistic chiropractic approach to patient care. Results: Seven thousand, two hundred sixty-two potentially relevant articles were identified.
Eleven of these studies included adults as the majority of patients; for these studies the age of the patient experiencing the adverse event was never reported. Most of the adverse events that have been identified in children were mild and included pain, bruising, and worsening of symptoms. The few adverse events rated as moderate or serious included one pneumothorax, 2 infections, and 2 cases of complications from needles left in the body. Methods: This study was approved by the Institutional Review Board of Life University (Atlanta, Georgia).
A 26-item questionnaire was sent to 9000 subscribers of an online newsletter from Midwifery Today Magazine.
The first domain identified demographics (midwife credentials, age, years in practice, and place of practice). The second domain queried participants regarding their formal and postgraduate training on the subject of chiropractic.
The third domain attempted to identify their experience (ie, positive or negative experience) with chiropractic personally and professionally as it pertains to pregnancy and infant care. The fourth domain asked their opinion about the safety of chiropractic care for pregnant and pediatric patients.
The fifth domain surveyed their knowledge regarding the scope of practice of chiropractic for pregnant and pediatric patients. The respondent ranged in age from 41 to 50 years with practice experience ranging from 6 to 10 years. With respect to their training on chiropractic, 31% (n=57) reported receiving formal education (ie, during midwifery education) on the subject of chiropractic. Fifty-five of the 157 who did not indicated receiving some education on chiropractic through continuing education seminars. With respect to the midwife responders’ experience with chiropractic, 95% (n=176) admitted to making a professional referral to a chiropractor with 73% (n=137) having referred an infant to a chiropractor.
Ninety-two percent (n=171) reported being chiropractic patients with another 58% (n=124) presenting their child for chiropractic care. Over 90% indicated experiencing a positive experience as patients and with their child’s care.
All of the respondents perceived chiropractic was safe for pregnant patients, while only 97% considered chiropractic safe for children.
An overwhelming majority of the responders (98%) indicated that chiropractors work with birth professionals, while 92% indicated that they were knowledgeable about the role of chiropractic in prenatal care. Lastly, 75% indicated interest in learning more about chiropractic, with 86% wanting more evidence-based practice chiropractic. From the 809 articles reviewed, 18 articles met the full inclusion criteria and proceeded to data extraction.
Identified adverse events include local pain or soreness, swelling, mild fevers, and skin rashes.
Thus far, the majority of adverse events reported have been mild with few moderate or serious adverse events occurring in pediatric patients.
Total weight and body composition changes in response to weight reduction diets of varied protein content in midlife women.
Age-related changes in body composition for women include loss of lean mass and gains in total weight, fat mass and central fat deposition. There is growing evidence that diets with low-to-moderate carbohydrate and fat content and increased levels of high-quality protein are effective for weight loss. Greater subjective satiety is reported by subjects following test meals containing whey protein compared to other protein sources. The beneficial effects of whey protein on satiety, thermogenesis, and lean body mass protection suggest that whey may be a preferred protein source for weight loss treatment. The specific aims of this study are to assess weight loss in subjects receiving energy-reduced dietary regimens and to evaluate parameters of weight and body mass change between the 3 treatment groups.
Study Design: We are conducting a randomized, controlled pilot feeding study to evaluate the effect of different dietary protein sources on weight loss. Endpoint measures include body weight and body composition data obtained at baseline and at 8 weeks for dietary treatment. The HP diet and the WP diet produced greater total fat loss and less total lean tissue loss than the CD.
Conclusions: Preliminary data shows that across treatment groups, the high-protein diets conserved lean tissue and promoted reduction of fat tissue. Trials investigating TCM must be conducted with increased methodological rigor to be of value in evaluations.
The single included study suggesting that acupuncture may be safe and efficacious in CFS is limited in applicability by the use of sham acupuncture as the control.
Integration and interface between naturopaths and conventional rural care: empirical findings from a grass-roots research project. The worsening epidemic of DM in the United States, along with the increasing prevalence of obesity, insulin resistance, and IGT, render the identification of promising interventions for these states a matter of some urgency. Jon Adams, University of Queensland, School of Population Health ,University of Qld, Herston, Queensland, 4006, Australia. While lifestyle interventions based on dietary pattern and physical activity can delay or prevent the onset of diabetes and reduce cardiovascular risk, adherence at the population level is severely limiting. Pharmacotherapy offers promise for diabetes prevention, but with associated high costs, unacceptability to many patients, and potential toxicity.
In this context, the potential role of chromium (Cr), an insulin cofactor, in IGT is of great interest. Proposed, therefore, is a randomized, double-blind, placebo-controlled pilot trial conducted at the Yale Prevention Research Center to investigate the effects of daily Cr for 6 months at 2 dose levels on serum measures of glucose tolerance and on endothelial function in adults with IGT, IFG, and IR. The study is powered to detect a clinically meaningful effect of Cr supplementation at either dose on glucose control, and to compare the two doses for equivalence. The study will investigate effects of Cr on both measures of glucose tolerance (glucose, insulin, OGTT) and brachial artery endothelial function, thus combining serum measures with a physiologic test of Cr effects on the vasculature. The proposed study will generate much needed data regarding the efficacy of Cr in those at risk for type 2 diabetes and offers the promise of guiding practice, as well as directing future study. By contributing to knowledge related to potential diabetes prevention strategies, this study addresses one of the more pressing public health issues in the United States today.
Risk to human subjects in this study is a minor increment over minimal due to the administration of nitroglycerin as a control in BARS testing. Secondary outcomes: (4) It will show improved well-being, as measured by elevated melatonin and DHEA. Unlike many relaxation therapies, energy healing requires no participation by the patient, a feature that makes it particularly attractive in the hospital setting, where patients are often anxious, depressed, in pain, or sedated.
Despite the increasing use of energy healing, few studies have looked at its benefits and even fewer at its underlying mechanisms of action. In this pilot study, we examined the effects of an energy healing modality known as Reiki on the autonomic nervous system (ANS) and the hypothalamus-pituitary-adrenal (HPA) axis, both of which participate in the stress response and stress-induced pain and disease progression. Subjects rested for 10 min before baseline heart rate and blood pressure were measured and blood was drawn to determine cortisol, ACTH, and DHEA levels, using commercial immunoassay kits. Subjects then received a 30- to 45-min Reiki or Pretend Reiki session followed immediately by post-session heart rate and blood pressure measurements and at 2h by blood draws. When asked whether they thought they were in the Reiki or Pretend Reiki group, about 70% of the participants reported that they believed that they had received a true Reiki session. This suggests that the beneficial effects of Reiki on physiology, as compared to the Pretend Reiki, cannot be explained solely by the placebo effect. Issac Amponsah, Faculty of Pharmacy Kwame Nkrumah University of SC, Knust, Kumasi, 233, Ghana. Effects of ultra-low dilutions of sabal serrulata on human prostate cancer growth: mechanistic studies.
Hakima Amri, Georgetown University, Basic Science Bldg, 3900 Reservoir Rd NW, Washington, DC 20007. Finally, serum protein differential expression was carried out using 2-dimensional gel electrophoresis followed by mass spectrometry analysis. Effect of mind-body medicine skills on elements of emotional intelligence in medical students. Yet studies have reported that traits such as altruism and empathy tend to decline throughout medical school training. In an effort to foster medical student self-awareness and mindfulness, which may improve their EI, Georgetown University School of Medicine (GUSOM) offers an experiential course to undergraduate medical students in mind-body medicine skills. The purpose is to expose students to a variety of mind-body approaches including meditation, imagery, as well as group sharing and listening generously for self-awareness and reflection. The aim of this study was to assess the impact of the Mind Body Medicine Skills (MBS) course on perceived stress, mindfulness, and elements of EI including intrapersonal capacities (attention to feelings, mood repair, clarity of feelings) and interpersonal capacities (perspective-taking, empathetic concern, and personal distress in response to distress in others).
The intervention group (n=30) was comprised of first year medical students who self-selected to participate in this elective.
The control group (n=36) included students from the first year class who completed the surveys but did not take the MBS course.
Four questionnaires were completed at the start and end of the spring semester by all study participants: the Perceived Stress Scale (PSS), the Mindful Attention Awareness Scale (MAAS), and a survey of EI developed by Stratton et al (2005) comprised of the Trait Meta-Mood Scale and the Interpersonal Reactivity Index.
ANCOVA was used to compare the MBS and the control groups at the end of the semester, controlling for beginning scores.
Patient perspectives of integrative and primary care management of back and neck paina€”qualitative findings from a randomized clinical trial. These conditions are additionally some of the most common reasons why patients use complementary therapies, often without dialogue with conventional care providers. The focus groups were conducted separately for those in the integrative vs the conventional treatment groups. The interview data were transcribed ad verbatim and analyzed utilizing inductive content analysis technique.
Eliane Angst, UCLA Center for Excellence in Pancreatic Diseases, 675 Charles E Young Drive South, Los Angeles, CA 90095.
A significant reduction in cell numbers was seen with quercetin concentrations of ~30 AµM and a maximum effect at ~75 AµM. In MIA PaCa-2 cells a ~65% reduction in cell number was seen with 75 AµM of quercetin after 48 hours.
Starved BxPC-3 cells treated with 75 AµM quercetin showed a ~95% reduction in cell number after 48 hours.
Conclusion: These results suggest that quercetin has a potent growth-inhibitory effect in pancreatic cancer cells in vitro.
Additional experiments to investigate the underlying mechanism of growth inhibition and animal studies are underway. Flovanoids may reveal to be potent anticancer drugs found in our daily food, leading to specific diet recommendations.
These can be taken together to qualify as an academic minor in many of the conventional MA or PhD programs, often forming the basis of a thesis or dissertation required for the terminal degree. In the fall of 2009, the university will launch a doctorate of nursing practice with a focus in integrative health and healing. Georgetown University developed a concentration of CAM within its Masters in Physiology program in 2003.
We address the multicultural perspective, comparing data collected in Canada and Europe to those in the United States. The reason for this is that results on the health-promoting effects of spirituality and religiosity cannot easily be transferred from the United States to countries with different cultural and religious backgrounds. Thus, one has to recognize different concepts of spirituality, different attitudes towards its utilization, and objections against the implementation of it in a particular medical system.
In Germany, 3 colleagues have founded the Transdisciplinary Working Group on Spirituality and Health, and in Canada the Canadian Research Network on Spirituality and Health has been active for a couple of years.
Data and approaches from these different networks will be combined into this symposium.Dr BA?ssing is an associate professor at the University of Witten, Herdeckea€™s Faculty of Medicine, where he directs the research group Spirituality and Health. The effect of a€?acupuncture for losing weighta€? on the level of blood sugar: a survey on the mechanism.
Hoda Azizi, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Beijing, Beijing, 100029, China.
Material and Methods: In this clinical trial study, 66 patients were included in case and control groups. Blood sugar was examined just before inserting needles and immediately after withdrawal of needles. Conclusion: Our results suggest that the mechanism of acupuncture in losing weight is significantly related to making an increase in BS. John Balletto, Center for Muscular Therapy, Inc, 545 Pawtucket Avenue, Mailbox 304, Pawtucket, RI 02860-6046. As with business startups that begin informally and successfully mature into larger enterprises, growth brings new organizational challenges, together with greater visibility and opportunity. The maturation of massage as a healthcare profession increases the need for a process to formalize the synthesis of massage therapy knowledge from clinical experience and research—to collect what we know and to make such baseline knowledge widely available to practitioners, consumers, and other healthcare stakeholders. The present paper lays out the motivations and framework for creating massage therapy guidelines that are informed both by research and by clinical experience.
It also acts as a report to the massage therapy profession and to other stakeholders about the work of the Best Practices Committee of the Massage Therapy Foundation since 2006. And it has the additional goal of providing a healthcare literature basis for future academic discussions of massage. The discussion here is based on a definition from the Institute of Medicine and on research into the nature of expertise. Topics addressed include guideline creation, credentialing of complementary and alternative medicine practitioners, definition of competence, and the increasing role of technology (that is, informatics) in managing training and task-necessary competencies. The roles of transparency and a wide and open peer review are emphasized as essential to the usability and credibility of guidelines. Health Canada issues consumer advisories regarding the safety of marketed health products, yet the criteria for issuing advisories have not been evaluated for consistency or objectivity.
The Causality Algorithm used by Health Canada was used to rate degree of association between the adverse events (AEs) and the products. The Severity of Adverse Events Scale, developed by the National Cancer Institute, was used to determine the severity of the AEs. Most NHP AWRs were issued based on potential AEs from contamination and adulteration, whereas most of the AWRs for therapeutic drugs were issued due to actual AEs.
Of the 6 NHP AWRs issued for actual AEs, 3 (50%) were unassessable for severity, whereas of the 28 AWRs issued for actual therapeutic drug AEs, 1 (3%) was unassessable for severity. The origin of reports for NHPs tended to be from foreign sources or Health Canada, whereas reports for therapeutic drugs were mostly issued by Health Canada in conjunction with drug manufacturers. The potential of a mistletoe (Viscum album L) extract to alleviate adverse effects of cancer chemotherapy: an in vitro study. Stephan Baumgartner, University of Bern, Institute of Complementary Medicine KIKOM, Inselspital, Bern, BE, 3010, Switzerland. We investigated the effect of a mistletoe extract on PBMC with and without concomitant treatment with cyclophosphamide and compared viability and replication of normal PBMC with that of a T-cell leukemia cell line. The results motivate further preclinical and clinical investigations of mistletoe extracts as an adjuvant medication in cancer therapy to alleviate side effects of conventional therapy. Stephan Baumgartner, Institute of Complementary Medicine KIKOM, University of Bern, Inselspital, Imhoof-Pavillon, Bern, BE, 3010, Switzerland. We investigated the potential of a commonly used plant pathogen–system, Arabidopsis thaliana infected with the virulent bacteria Pseudomonas syringae (pv tomato strain DC3000), regarding its response towards a homeopathic treatment.
Compared to Bion (a common SAR inducer used as positive control), the magnitude of the treatment effect of Biplantol was about 50%. None of the other tested preparations yielded significant effects in the overall evaluation. The purpose of this study was to determine remedy effects on a common quantitative measure of complexity, the correlation dimension (D2), of human sleep electroencephalography (EEG).
High Hostile subjects increased complexity at C3 and Pz, but decreased complexity at O2 during stage 3 sleep on CC.
In the high Anxiety-Sensitive subjects, CC caused significant increases in complexity at Pz and O1 during stage 3 sleep and at C3, C4, and Pz during stage 4 sleep.
CC increased complexity significantly at Cz, C4, and O2 during REM sleep in only the high Anxiety-Sensitive subjects. The purpose of the present study was to determine whether or not the objective measure of polysomnographically-recorded all-night sleep recordings can distinguish verum homeopathic remedies from placebo in human subjects. NV produced more marked effects on increased shifts in sleep stages, with a growth in effects from night 22 to 23. This study examined the effects of olfactory administration of a polycrest homeopathic remedy Sulphur on heart rate variability (HRV). The Sulphur was given at dilution factors used for preparing 6c, 12c, and 30c potencies (1 potency per session, with potency order randomized), but for each potency, the test solutions were succussed to different degrees (stirred without shaking, 10, 20, or 100 succussions). Homeopathic remedies increase spectral electroencephalographic power during sleep in healthy young adults. The purpose of the present study was to assess the effects of verum vs placebo homeopathic remedies on spectral qEEG measures of polysomnographically-recorded all-night sleep recordings.
Evaluating a nonlinear dynamical model for human flourishing: Relationship of PANAS positive-to-negative-affect ratio and global health and well-being. The purpose of the present study was to compare global physical health (GPH) and well-being ratings of young adults whose P:N mood ratios fell above vs below the Losada line. Despite higher (MCSD) scores in PF, a small sex and age difference between groups, ANCOVAs controlling for MCSD, sex, and age still showed statistical significance of the above PF vs PL group differences.
Gurjeet Birdee, Osher Research Center Harvard Medical School, 401 Park Drive, Suite 22-A West, Boston, MA 02215. We identified the prevalence of CAM modalities used and the characteristics of users among the pediatric population.

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