Ear level tinnitus masker wajah,wholesale earring gift boxes youtube,noiser tinnitus kaufen android - Downloads 2016

Author: admin, 14.10.2013. Category: Treatment For Tinnitus

The diagram below illustrates the noise levels and corresponding lengths of exposure at which damage to the auditory system can occur.
Alle hier vorgestellten Therapieergebnisse, wurden nur mit der hochdosierten Low-Level-Lasertherapie nach Dr. We hypothesize that relief in the ear with the tinnitus complaint may result from oral intake of Clear Tinnitus for patients with severe disabling tinnitus in whom the factor of aeration of the middle ear and that of eustachian tube dysfunction is identified and treated. Interference in aeration of the middle ears accompanying allergy and inflammation of the upper respiratory tract has been identified via a medical-audiological tinnitus patient protocol (MATPP) to be a factor that can influence the clinical course of subjective idiopathic tinnitus of the severe type [6-8]. Historically, the influence of aeration of the middle ear "effecting permeability of the eustachian tube" was reported by Politzer in 1863 [9].
Since 1979, the tinnitus clinic of the Health Science Center at Brooklyn, State University of New York, and the Martha Entenmann Tinnitus Research Center, Inc., have reported on more than 10,000 patients who had subjective idiopathic tinnitus (seen in neurotological consultation) and completed the MATPP. The prospect of a trial of Clear Tinnitus to attempt tinnitus relief in a selected cohort of patients who have subjective idiopathic tinnitus and exhibit objective evidence of interference in eustachian tube function provided a clinical opportunity to use our established experience to test the efficacy claimed for this preparation. We selected 15 individuals with reported subjective, severe, disabling idiopathic tinnitus lasting at least 1 year. The parameters of the patients' tinnitus included tinnitus intensity, location, masking characteristic, and duration.
All 15 subjects reported the tinnitus to be of the severe disabling type lasting for at least 1 year. The homeopathic preparation for tinnitus relief- Clear Tinnitus-was taken on a daily basis.
The patients in this study completed multiple measures for evaluating the subjective idiopathic tinnitus and the hypothesized tinnitus relief.
We identified for each patient multiple risk dimensions known to influence the clinical course of subjective, idiopathic, severe, disabling tinnitus, with a focus on fluctuation of aeration of the middle ear and eustachian tube dysfunction. We used multiple objective measures to evaluate the risk dimensions for each tinnitus patient.
The measures included audiological testing via puretone audiometry and speech audiometry performed using a Beltone 2000 audiometer. Extensive scientific research has been carried out on the preparation's chemical composition, and pharmacological and clinical research has focused on its individual herbs. We performed all statistical analyses using the Statistical Package for the Social Sciences (SPSS Release 14) [19].
Regression analysis failed to detect any trends in the change in response to audiometric tests across the hearing spectrum; thus, we could not derive coefficients of change for testing. Ultra-high-frequency audiometry (UHFA) did not show any clinically significant change in threshold at 10,000-20,000 Hz before and after testing with airconduction high-frequency or electrical high-frequency audiometry.
In the 11 patients completing the study, all masking curves were either type I or type IV according to Feldmann's classification system.
Minimum masking level (MML) changes for the right ear before and after the study are reported for 10 individuals, as 1 had no tinnitus at the end of the study.
We established LDLs at 250-8,000 Hz for the right and left ears before and after the study (Table 5). For the tympanogram type, using -100 mm H2O as abnormal, three of the seven responders went from type C tympanogram to type A. Both responders and nonresponders (N = 11) correlated to recorded MEPs before and after the study (see Table 1).
We found improvement in aeration of the middle ear, as established by tympanometry and supported by physical examination of the tympanic membranes, in eight patients.
Five of the seven patients reporting subjective tinnitus abatement recorded MEP improvement at the start and conclusion of the study.
A nonsignificant difference occurred over time when testing for a quadratic change over the course of the study, with a lowering of the total significant abnormal recordings.
We analyzed the results of the outcome questionnaires as an average for all patients who completed the study (N = 11) and separately for the responders (n = 7) and nonresponders (n = 4; Table 7). The measurement of depression test (Zung) indicated a mean change of -2.27 before and after the study, which also was not considered statistically significant. In summary, a statistically significant improvement in one or more of the outcomes (TII, TAI, TRQ) was identified in six of seven patients reporting tinnitus relief.
This study differentiated between the efficacy of the Clear Tinnitus preparation for maintenance and improvement of MEP and the correlation of the MEP improvement with reported tinnitus relief. Seven of the 11 patients reported relief from severe, disabling-type tinnitus after oral intake of Clear Tinnitus. The clinical course of the tinnitus patients selected for this study was identified, by their clinical history and physical examination, to have been influenced by fluctuation of MEP. The patients' clinical history was positive for the association of tinnitus intensity fluctuation with the subjective report of ear blockage-specifically, increased tinnitus intensity with increased ear blockage and vice versa.
The regression analysis failed to detect any trends in a change in response with audiometric tests across the hearing spectrum; thus, we could not derive coefficients of change from testing.
The range of normal and abnormal MEP varies in reports from different investigators (from -25 mm H2O to -100 mm H2O) [20-26]. The QEEG testing was recommended in this study to improve the accuracy of the tinnitus diagnosis.
Clinically, when interpreted in terms of the tinnitus dyssynchrony-synchrony theory, the QEEG data in this study are considered to provide an understanding of the clinical course of the tinnitus in the patients in this study and of the efficacy of the Clear Tinnitus therapy attempting tinnitus relief [2]. The outcome results reflect the dilemma of all professionals involved in attempting to evaluate modalities of therapy attempting tinnitus relief: specifically, how a subjective response becomes one of affect and how a subjective response might be objectified [1,13]. The 11 tinnitus patients who completed the study demonstrated with tympanometry a statistical and clinical significance in MEP improvement (n = 8) or maintenance of MEP (n = 3) or both. The subjective report of tinnitus relief in those seven patients was supported by objective measures of analysis in five patients; the remaining two responders recorded normal MEP before and after the study. We gratefully acknowledge the support of Clear Products and the Martha Entenmann Tinnitus Research Center, Inc., for this educational and research effort. The apple cider vinegar has an anti-inflammatory and antifungal agent, so it is very good for treating any underlying infection, which can be contributing to your tinnitus. You take about 120 mg to 240 mg of the ginkgo biloba extract that contains about 6% to 12% terpenoids and 24% to 32% flavonoids. You take the ginkgo biloba extract daily, with ideal doses are divided into 3 or 4 times per day for 6 weeks in order to get the positive results. However, you should consult a doctor before you start the treatment because this herb can interact with some medications. Onions have antibacterial and medicinal properties that help you in treating ear infections causing tinnitus. The saline solution will help you in treating tinnitus that is caused by excessive fluid or blocked nasal passages in your sinuses. You can apply a nasal spray bottle in order to inject this solution to every nostril till it begins draining into your back of throat. In addition, you should do this solution 3 times per day till your nasal passages are very clear.
Alternatively, you can drink garlic capsules for a few days or you use this herb for your cooking. You drink this ginger tea solution 2 or 3 times per day for a few weeks to reduce your tinnitus symptoms.
The chewing process will help you reduce the pressure inside your ear, which can be causing tinnitus. Another way to deal with tinnitus is eating more foods such as pumpkin, which is very rich in vitamin A that can help you to get rid of tinnitus.
To get rid of tinnitus by applying pumpkin, you just need to include it into your soup or salad. To know more about other health problems & effective homemade remedies, go to our main Home RemediesA page. VKool encourages comments, but please remember: Play nice, keep it clean, stay on-topic, and avoid promotional content. Role of worry in patients with chronic tinnitus and sensorineural hearing loss: a preliminary study. 1Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Via Roma 16, 22032, Albese con Cassano, Como, Italy.
3Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Via Roma 16, 22032, Albese con Cassano, Como, Italy.
4Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, University of Maastricht, Maastricht, The Netherlands. 5Department of Psychiatry and Behavioral Sciences, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA. Tinnitus-related distress appears to be more strongly associated with multiple psychological factors than with any perceptual properties of tinnitus.
Effect of local irradiation with 630 and 860 nm low-level lasers on tympanic membrane perforation repair in guinea pigs. Otolaryngology – Head and Neck Surgery Research Center, Rasool Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran. Objective: In this study, we evaluated the effect of low-level lasers on the healing of tympanic membrane perforation, one of the most common otological pathologies. Methods and materials: Twenty-four guinea pigs were randomly assigned to either the experimental or control group. Conclusion: The results show that the combined application of 630 and 860 nm lasers had a significant effect on the healing of tympanic membrane perforation, and on the prevention of thick fibrotic or atelectatic neomembrane formation. Effect of low-level laser treatment on cochlea hair-cell recovery after acute acoustic trauma.
We investigated the effect of low-level laser radiation on rescuing hair cells of the cochlea after acute acoustic trauma and hearing loss.
Moderate and severe sudden deafness treated with low-energy laser irradiation combined with auricular acupoint sticking. Department of Rehabilitation Medicine, The First Affiliated Hospital of Xinxiang Medical College, Weihui 453100, Henan Province, China. To test the therapeutic effect on moderate and severe sudden deafness treated with low-energy laser irradiation on acupoint and external auditory canal combined with auricular point sticking (APS) and as compared with electroacupuncture.
Two hundred and fifty-eight cases of moderate and severe sudden hearing loss were randomly divided into an observation group 1, an observation group 2 and a control group, 86 cases in each group. Both of low-energy laser irradiation on acupoint and external auditory canal combined with APS and electroacupuncture are able to decrease frequency audiometry, improve auditory function, and the therapeutic effects are better with prolongation of treatment time.
Effect of low-level laser therapy on cochlear hair cell recovery after gentamicin-induced ototoxicity. Department of Otolaryngology-Head & Neck Surgery, Dankook University College of Medicine, Cheonan, Korea. Intravenous laser irradiation of blood for the combined treatment of patients presenting with chronic sensorineural hearing loss.
A method for the treatment of chronic sensorineural hearing loss (CSNHL) is proposed that includes administration of trental followed by intravenous laser irradiation of blood (IVLBI). The application of supravascular laser irradiation of blood for the treatment of cochleovestibular disorders. A total of 165 patients presenting with neurosensory impairement of hearing and Meniere’s disease were treated by supravascular (extracorporeal) laser irradiation of blood.
Department of Otorhinolaryngology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran. BACKGROUND: Despite the high prevalence and morbidity, tinnitus still remains an obscure symptom. METHODS: It was a self controlled clinical trial study on 61 outpatients with subjective tinnitus. CONCLUSIONS: Transmeatal low-level laser irradiation is effective for the treatment of tinnitus and some variables like age and job can affect the treatment outcome. Ear, Nose, and Throat Department, IRRCS San Raffaele Hospital, Vita-Salute University, Milan, Italy.
OBJECTIVE: To assess the efficacy of low-level laser therapy (LLLT) for Meniere’s disease (MD). CONCLUSIONS: In our experience, LLLT seems to prevent vertigo spells in MD, although results indicate that it has a slower action than betahistine.
OBJECTIVE: To evaluate effectiveness of 5 mW laser irradiation in the treatment of chronic tinnitus. CONCLUSION: Transmeatal, low power (5 mW) laser irradiation was found to be useful for the treatment of chronic tinnitus.
The treatment of patients with chronic tinnitus is very problematic and therefore otologists are trying to discover more suitable courses of therapy. Transmeatal cochlear laser (TCL) treatment of cochlear dysfunction: a feasibility study for chronic tinnitus. Department of Otolaryngology, Head and Neck Surgery, Ludwig-Maximilians-University of Munich, D-81377 Munich, FRG.
Low-level-laser-therapy (LLLT) targeting the inner ear has been discussed as a therapeutic procedure for cochlear dysfunction such as chronic cochlear tinnitus or sensorineural hearing loss.
Hyperacusis treatment with a combination of laser therapy, pulsed electromagnetic field therapy and reactive oxygen speciment control.
Patients with grave hyperacusis seem to have the largest dB-improvements from this therapy.
The IXX Annual Meeting of The American Society for Laser Medicine and Surgery, Lake Buena Vista, Florida. A) The objective of the study was the documentation of the biostimulative effects of LLLL in high energetical dosages (measured in j) by audiometry changes of a statistically relevant number of patients. According to a study of the university of Cologne1) by 2030 every second German will be suffering from impairments of the inner ear. The audiometry belongs to the diagnostical standard equipment of medical offices and acousticians and is universally being used as a basic diagnostic by trade operative associations and industrial medicine for the purpose of examinations and appraisements. The energy was transmitted by 3 laser diodes with a wave length of 830 nm und 3 diodes with a wave length of 635 nm; it was administered via meatus and mastoid.
In the case of the initial audiometrical results (pretherapeutical findings) the evaluation of the mean value of all readings reveals a clearly reduced average course of the hearing curves of the air and bone conductions over all frequencies, with low points in the frequency sector around 6 kc and the frequency sector around 12 kc (sensorineural hardness of hearing, oblique descension).As expected, the bone conduction is situated above the air conduction in all frequencies. The comparison of all pre- and posttherapeutical readings over all frequencies reveals statistically highly significant results in the case of the air and bone conductions.The values of the air conduction, which are slightly higher as those of the bone conduction, indicate that the LLLL has additional positive therapeutical effects on the sound conducting structures of the middle ear. The grouping of the readings according to age groups and 3 frequency intervals results in findings that are biologically plausible as far as both the air and the bone conductions is concerned. As to the grouping of the readings according to the duration of the disease and 3 frequency intervals, the patient group with the shortest duration of the disease (0.6 years) has the best initial values and obtains the best final results with the smallest quantity of transfered energy. The grouping of the readings according to energy quantities reveals a clear correlation between the total quantity of the transfered energy and the therapeutical results that were obtained.
In this respect, the results of the study at hand not only refer to the fundamental working model of the cellular energy transfer6) from 1998, which was based on quantum mechanics, but confirm its conclusions as well, namely, that cellular regeneration processes do take place, if the mitochondria in question are stimulated to an increased production of adenosine triphosphate (ATP) by sufficiently large quantities of LLLL. Patients suffering from hyperacusis were treated twice a week with a combination of therapeutic laser, pulsed electromagnetic field and the control and adjustment of Reactive Oxygen Species (ROS). 59 patients with neurosensory hypoacusis and 45 with Meniere’s disease underwent helium-neon laser intra- or supravascular radiation of blood. Lightdosimetric quantitative analysis of the human petrous bone: experimental study for laser irradiation of the cochlea. BACKGROUND AND OBJECTIVE: Application of laser irradiation targeting the inner ear has to be investigated for therapeutic effectiveness in cochlear injury and dysfunction.
RESULTS: The transmission of light across the tympanic cavity and the promontory depends strongly on wave-length of the laser and the position of the radiator. CONCLUSION: The strong dependence of the cochlear light distribution on various irradiation parameters demonstrates the impact of preclinical lightdosimetric investigations for effective individual laser irradiation of the human cochlea. The light distribution inside the cochlear windings produced by irradiation of the tympanic membrane was quantitatively measured ex vivo for wavelengths of 593, 612, 635, 690, 780 and 805 nm by means of video dosimetry.
Comprehensive laser rehabilitation therapy of tinnitus has proven successfull and beneficial for treatment of this widespread civilization disease. Tinnitus is an auditory perception apearing without an objective sonic source from the outer environment. Our last study on a group of 200 patients in the course of three years was finalized in February 2002 and published in June 2002. Our group consisted of 72 patients, 49 males, 23 females, age ranging between 16 to 92 years.
We strictly appeal to maintain the direction of the vector of aiming the beam – in fact the target structure of the helix is a shape of several square milimeters.
Percentage scale – complaints evaluated 100 per cent at the beginning of therapy (Blue), according to the level of relief decreased (Green) to 80, 70 etc.
This evaluation is identical with our previous study, and it enabled us to compare easily the results of both studies.
It was interesting to compare our latest results (LLLT only) with those of our previous studies, i.
We have been positively surprised that in general the ratio of individual four groups remained similar. In the group evaluating improvement as less than 50 per cent the leading role of LLLT can be evidenced best. 22.2 per cent patients suffering from tinnitus never more after treatment with therapeutic laser is a great success of LLLT. Ear muffs or ear-plugs should be worn when activities such as mowing the lawn or using a chainsaw are undertaken.
Our goal was to establish the efficacy, in a 12-week period, of Clear Tinnitus for tinnitus relief in patients with tinnitus of the severe, disabling type.
We employed a descriptive data analysis method across dimensions of risk to evaluate a base of multidimensional evidence to support our hypothesis. We clinically identified all patients in this study as having subjective idiopathic tinnitus of the severe type lasting at least 1 year.
A focus on risk factors for each tinnitus patient provides an increased level of flexibility for interpretation of the clinical significance of the results of a treatment method and its future application for tinnitus relief. Its application for hearing improvement and tinnitus relief has been reported in his classic textbook: "When there are accumulations of secretion in the middle ear, or anomalies of tension in the sound conducting apparatus which bring about an increased pressure in the labyrinth, it has been found inflations of air into the middle ear and rarefaction of air in the external meatus are often the most effectual means by which these subjective noises are overcome" [10]. Significant tinnitus relief was obtained in approximately 10-15% of tinnitus patients in whom identification of and satisfactory treatment for the factor of aeration of the middle ear and of eustachian tube dysfunction was completed [6-8,11,12]. Using multiple measures of analysis of risk factors, this study presents the results and conclusions of attempted tinnitus relief with Clear Tinnitus. The 15 patients variously reported a bilateral tinnitus location (n = 12), a unilateral tinnitus in the right ear (n = 2), bilateral tinnitus in the head and ears (n = 1), a tonal quality to the tinnitus (n = 11), a noise band (n = 1), a combination tone and noise band (n = 3), and high frequency (n = 15; Table 1).
All tinnitus patients completed an MATPP to identify the clinical type of tinnitus and factors influencing the clinical course of their tinnitus [6-8,11,12].
The specific regimen consisted of three capsules taken with food two times daily for 3 months. The answer to the final question was whether the reported tinnitus relief was considered significant to the patient.
We originally planned to use the data obtained to provide a base for a multivariate risk-benefit stratified analysis of the significance of the reported tinnitus relief. Conventional pure-tone audiometry conducted at 250-8,000 Hz (including 3,000 and 6,000 Hz) showed no significant difference in thresholds for either ear at any of the frequencies before and after testing all 11 subjects.


Among our 15 patients, 12 originally reported tinnitus in the ears bilaterally, 2 originally reported unilateral tinnitus in the right ear, and 1 reported tinnitus in the head and ears bilaterally.
Five were type I before the study, four were type IV before the study, and two were mixed (type I for one ear and type IV for the other ear). No clear trend in the data for either ear was demonstrated by the mean change in LDL before and after the study.
Two patients with a normal starting MEP that remained unchanged reported a positive tinnitus relief outcome, whereas one patient with a normal starting MEP that remained unchanged reported negative tinnitus relief. MEP improvement was recorded in three patients and remained unchanged in one, who had a normal MEP both before and after the study. Results of quantitative electroencephalography (QEEG) recordings of the four EEG frequency bands for the 11 patients completing the study. Results of quantitative electroencephalography (QEEG) recordings of the four EEG frequency bands for the seven responders.
Five responders reported positive significance of the tinnitus relief, and two reported it as negative (see Table 6). An improvement in the TII and TAI scores of 2 units or more was reported by four of the seven.
All patients who completed the study demonstrated via tympanometry a statistical and clinical significance in MEP improvement (n = 8) or maintenance of MEP (n = 3) or both (see Table 1). As identified with tympanometry, five demonstrated a significant improvement in MEP, and two showed maintenance of a normal MEP (see Table 1).
This clinical medical-audiological approach provided a basis for objective interpretation of the reported subjective tinnitus relief with the Clear Tinnitus treatment.
The MATPP electrodiagnostic cochleovestibular test battery identified the tinnitus to be predominantly a cochlear type, bilateral and unilateral, with a middle-ear and central component. Physical examination of the tympanic membranes before and at the conclusion of the study identified mild to moderate scarring of the tympanic membranes consistent with eustachian tube dysfunction.
Clinically, this suggests to the limits of examination that the site of Clear Tinnitus action is not cochlear in location. Pitch match did not correlate with outcome measurements, masking curve type, MMLs, or LDLs. Clinically for this study, tympanometry values for a normal range of MEP were established to be from 0 to -50 mm H2O.
It could function as a monitor for establishing the efficacy of the therapeutic modality-Clear Tinnitus-attempting tinnitus relief and aid in understanding the clinical course of the tinnitus as reflected in brain function of memory, consciousness, attention, and affect [3,12]. The low power of the analysis for the nonresponders (n = 4) precluded any conclusion or clinical correlation. To determine patients' baseline responses, we administered questionnaires to record subjective tinnitus at the outset of the study and again at the conclusion. If the reality of the absence of a tinnitus cure at this time is accepted and tinnitus relief is the goal, is relief expected for the tinnitus sensation or for the annoyance and intrusion into one's lifestyle, as manifested in the behavioral response of affected patients to the presence of the tinnitus? Of the 11 patients, 7 with severe, disabling tinnitus and fluctuation of aeration of the middle ears (diagnosed with the MATPP as a factor influencing the clinical course of their tinnitus) reported tinnitus relief with Clear Tinnitus.
These results indicate that a slightly larger sample size might have changed the outcome of this analysis. Ginkgo biloba plays an important role in improving the blood circulation that in turn will improve the ear functioning as well as reduce the ringing sensations. This herb has antibacterial properties that will help you in killing the bacteria, which can be causing your ear problem.
Garlic will help you relieve your tinnitus condition that is caused by cold weather or high altitudes. Mustard oil is known as a natural rubefacient that can help you in increasing the blood circulation. Pineapple can help you in lessening inflammation all over the body thanks to the existence of an enzyme that is known as bromelain.
Vitamin A is very important for the appropriate functioning of inner ear or cochlea that is responsible for transmission and reception of sounds.
In addition, you can have pumpkin steamed, stir-fried, stuffed, or grilled in baked dishes. After reading the writing of top 10 natural home remedies for tinnitus or ear ringing, hope that this writing helps you find out the best solution to get rid of your ear problem. One day after the induction of a 2 mm diameter, centred myringotomy in all animals, the tympanic membranes in the experimental group were irradiated with 630 and 860 nm lasers for 10 days. The distance from the external auditory canal wall to the malleus tip did not differ significantly between the two groups (p = 0.42).
The clinical efficacy of above two the rapies on moderate and severe sudden deafness is superior remarkably to that of conventional treatment. It is well established that antibiotic drugs such as gentamicin can damage hair cells and cause hearing loss. The study included 81 patients at the age from 20 to more than 60 years presenting with CSNHL. The study undertaken to evaluate the efficacy of this treatment confirmed its beneficial effect in patients with acute hearing disorders. The patients were irradiated with a 650-nm, 5-mW soft laser for twenty days and twenty minutes per day. The patients were randomly divided into two groups: group 1 patients received LLLT 20 min a day with a 5-mW soft laser for 6 mo, while group 2 received betahistine 16 mg twice a day for 6 mo.
Betahistine seems to have a faster action in spell reduction (p 0.05 comparing the 3-mo results between the two groups).
A 5 mW laser with a wavelength of 650 nm, or placebo laser, was applied transmeatally for 15 minutes, once daily for a week. In this study we wanted to evaluate the outcome of using a combination of EGb 761 and soft laser therapy. The patients underwent pure-tone audiometry, speech audiometry and objective audiometry tests.
Former studies demonstrate dose-dependent biological and physiological effects of LLLT such as enhanced recovery of peripheral nerve injuries, which could be of therapeutic interest in cochlear dysfunction. The combined set of therapies in this study should be a first choice therapy for all hyperacusis patients. B) The energy was transmitted with 3 laser diodes with a wave length of 830 nm and 3 diodes with a wave length of 635 nm; it was administered via meatus and mastoid. Even at the present time, the number of people all over the world, who are inflicted with long-standing impairments or acute diseases of the inner ear, amounts to millions. The patients all received an out-patient treatment, which consisted exclusively of a monotherapy. The patient group with the longest duration of the disease (14.5 years) has the poorest initial values and furthermore needs the largest quantity of transfered energy. The larger the quantitity of transfered energy, the higher the db-reductions that could be observed. 6b clearly shows the correlative (parallel) connection between the total quantity of transfered energy and the total reduction. The same applies for an augmentation of the total quantity of the transfered energy in the course of the treatment phases or per unit; in the latter case further technological developements on the part of the laser industry are indispensable, though.
Dosinetric analysis for low-level-lasertherapy (LLLT) of the human inner ear at 593nm and 633nm. Import of Radiation Phenomena of Electrons and Therapeutic Low-Level Laser in Regard to the Mitochondrial Energy Transfer. 245 observations in 42 ears on 26 patients were measured before therapy and after 10-20 therapeutic sessions. The treatment proved effective in acute neurosensory hypoacusis and Meniere’s disease. In vitro data demonstrate low-level laser-induced photochemical and photobiologic cell response, depending on cell type and irradiation parameters such as light dose. The external auditory meatus, the tympanic membrane (quadrants), and the mastoid bone were illuminated by a helium-neon laser (lambda = 593 nm) and diode lasers of different wavelengths (lambda = 635, 690, 780, and 830 nm). Transtympanal irradiation results in spatial intensity variations of a factor 4 to 10 within the cochlear windings.
Because of the observed spatial intensity variations, the optimal external light dose has to be chosen with regard to the tonotopy of the human cochlea. It is not natural for the dentist to ask, nor for the patient to inform the dentist about such a situation since it does not appear to be a dental indication. The transmission of light across the tympanic cavity and the promontory depends strongly on the wavelength.
Tinnitus can be subjective (heard only by the patient) and objective (sound can be even heard also by others). We have published three studies on this particular issue, and we are of the opinion that our results are being followed in several countries (Brasil, Cyprus, Sweden, Switzerland, Slovakia, Turkey, Japan, Germany etc.) and implemented in numerous clinics with significant results.
Since there have always been efforts to evaluate an exact role of LLLT in treatment of tinnitus, apart from medication and physiotherapeutic manipulation of neck vertebra as an integral part of the comprehensive therapy, we have decided to create a separate group of patients to be treated only with laser. Since our long-term experience in comprehensive treatment of tinnitus has been based on the triad of physiotherapeutic manipulation, medication, and LLLT, we were at a loss whether we would not harm our patients in a way, giving them only a part of the treatrment, mere LLLT.
It only confirms the leading role of LLLT within comprehensive laser rehabilitation therapy of tinnitus. Venues such as nightclubs or entertainment venues that have excessively loud noise should be avoided or ear protection used. The benefits of a risk-stratified multivariate analysis across dimensions of risk, originally planned for this study, could not be achieved owing to an insufficient final sample size [4].
We hypothesize in this study that relief occurs by identifying and treating the factor of aeration of the middle ear. The clinical history of each tinnitus patient reflected periods of tinnitus relief associated with fluctuation of tinnitus intensity and the location and degree of ear blockage.
Such an analysis provided information of both the sensory and affect components of the tinnitus complaint [15].
Tinnitus evaluation included pitch and loudness matching, masking curves, and loudness discomfort levels (LDLs).
A copy of the manufacturer's cGMP certification and standard operating procedures used in the production of Clear Tinnitus is maintained by Clear Products, Inc. We modeled recordings of audiometric tests across the hearing spectrum using nonlinear regression. The adverse reactions included gastrointestinal complaints (one with gastroesophageal reflux disease and one with bloating and constipation) and ear complaints (one with "ear spasms"). Likewise, speech audiometry did not show any significant difference for speech reception threshold or word discrimination scores before and after testing.
The quality was reported as tonal in 11 patients, as noise band in 1, as combined tone and noise band in 3, and as high-frequency in all 15.
After the study, five with type I remained unchanged, and three of the four with type IV remained unchanged.
For the left ear, the eight patients who had tinnitus after the study exhibited a reduction in the masking level of - 11.25 dB at 8,000 Hz (Tables 3 and 4).
Of the four who did not report improvement, three went from type C to type A (one on both ears, the other two on one of the two ears; see Table 1). Two patients whose MEP was abnormal to start but changed to normal reported positive tinnitus relief, whereas three patients whose MEP was abnormal to start but changed to normal reported negative tinnitus relief. The number of significant abnormal power recordings was identified with a normative database and analyzed by the Lexicor Corporation.
When tested by a paired Student's t-test for change over the course of the study, only the TII, the TAI, and the TRQ demonstrated a significant decrease in the patients' responses. One patient reported tinnitus relief, improvement in MEP, and no improvement in outcome measures.
A multidimensional method of analysis across dimensions of risk is recommended for all clinical studies attempting to evaluate the efficacy of therapeutic modalities attempting tinnitus relief. The clinical type of this tinnitus correlates with the patients' reports of tinnitus relief in five of seven. The reported improvement in MEP with tympanometry was associated with reported subjective abatement in ear blockage in the tinnitus ear and with evidence of increased aeration of the middle ear on physical examination of the tympanic membrane. Otoacoustic emission tests in the future may provide a basis for audiological coefficients of change. In the 11 patients completing the study, all masking curves were either type I or type IV, according to Feldmann's classification system. The Clear Tinnitus preparation did not significantly influence the tinnitus evaluation measures consisting of pitch match, masking curves, MMLs, or LDLs. The QEEG results are considered to be electrophysiological brain function responses hypothesized to reflect a synchrony of responses at the cortex in the central nervous system (see Fig. The delta band was significantly higher than the alpha and beta bands both for the overall cohort of 11 patients and for the 7 reporting tinnitus relief (see Table 5; see Figs.
In only one patient in this study, demonstration of the theta and its increase may reflect the persistence of the tinnitus and the ongoing development of a paradoxical memory for the dyssynchronous auditory signal-tinnitus [2,3,27-29].
Of the six outcome measures, only the TII, TIA, and TRQ reported the data to be statistically significant (as noted by the asterisk in the top row of Table 7). This study supports the hypothesis that identifying and treating the MEP fluctuation factor may provide tinnitus relief from a predominantly cochlear-type tinnitus. Quantitative electroencephalography - power analysis: An electrophysiologic correlate of brain function in subjective idiopathic tinnitus patients. Tinnitus reaction questionnaire-psychometric properties of a measure of distress associated with tinnitus. Tinnitus can be caused by an ear infection or injury, age-related hearing loss, high altitudes, exposure to loud noise, earwax blockage, upper respiratory infections, mineral and vitamin deficiencies, abnormal bone growth (ear bone changes), or diseases such as low or high blood pressure, a circulatory system disorder or diabetes. In addition, ginkgo biloba has antifungal and antibacterial properties, which can deal with any underlying infection, which can be contributing to your tinnitus condition.
In addition, mustard oil has antifungal & antibacterial properties that can help you in treating ear infections.
However, the writing is solely for the informational purpose, so you need to get advice from your doctor before applying any home remedy. Worry is a dispositional cognitive trait that involves a pervasive, non-specific, future-oriented proneness to fretting, which can foster negative affective states and catastrophic thinking about a specific trouble when the trouble is actual and present. Based on the above treatment, the observation group 1 was treated with low-energy laser irradiation on acupoint and external auditory canal (such as Ermen (TE 21), Tinggong (SI 19) and Tinghui (GB 2)), combined with APS at Gan (liver), Shen (kidney) and Neifenmi (endorine), etc. The therapy of low-energy laser irradiation on acupoint and external auditory canal combined with APS can replace the electroacupuncture therapy in treating moderate and severe sudden deafness.
It was equally effective as regards elimination of labyrinthine hydropsis in patients presenting with Meniere’s disease. The sensation of tinnitus was measured on a Visual Analog Scale (VAS) before and two weeks after treatment and they were compared by means of Wilcoxon signed ranktest.
According to American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guidelines, the main outcome for vertigo control was considered to be the number of spells per month in the 6 mo before treatment compared with the same parameter in the 6 mo of therapy. Audiometric examination did not show a statistically significant difference between the two groups. In our opinion, increased blood flow in the inner ear is the main mechanism leading to the therapeutic results. A questionnaire was administered which asked patients to score their symptoms on a five-point scale, before and two weeks after laser irradiation. To date, in patients with chronic tinnitus mastoidal and transmeatal irradiation has been performed without systematic dosimetric assessment. Pulsed Electromagnetic Field Therapy was also used and Reactive Oxygen Specimen were measured and controlled by an additional intake of antioxidants per os. This study, however, only reports on the objective outcome of the audiometry, taken before and after therapy. The examination and therapy included 348 patients and 215 right and 187 left inner ear organs (cochlea). The basic diagnostic for the documentation of the functional quality of the cochlea is the audiometry.
They were advised to take reasonable prophylactic measures against noise during (and after) the therapy. As expected, the bone conduction is once again situated above the air conduction in all frequencies; the intersection phenomena in the frequency sector between 6 and 8 kc show a downward tendency. One group was evaluated in short-term follow-up (immediately after therapy), another group was evaluated in long-term follow-up (4-6 months after therapy). The aim of the presented study was to determine the light dose received by the cochlear hair cells by using different irradiation modalities for the human petrous bone. The spatial distribution of transmitted light in the cochlear windings was measured by means of a retrocochlearly positioned endoscopic CCD camera for image processing and was assigned to acoustic frequencies according to the tonotopic organization of the cochlea. The obtained results are enabling us to apply defined laser light doses to different cochlear winding areas.
Spatial intensity variations of a factor of 10 and more inside the cochlear windings have been measured. This investigation included 68 ears in 45 patients with disabling unilateral or bilateral tinnitus.
Studies published by these clinics show results which are almost identical with our experience. This was only possible thanks to our vast experience and long involvement in tinnitus treatments. We have to declare, that we have selected patients during the introductory examination, sorting out patients whose x-ray indicated a possibility of tinnitus caused by vertebral blockades. This is obviously caused by the absence of medication and physiotherapy, showing their supportive efect. On the other hand we must stress the necessity to apply the two remaining parts of our therapeutic triad as well, since medication and physiotherapeutic manipulation are integral parts of the general care of our patients, and we should not deprive the suffering of the means and methods capable of bringing them more relief, which we are aware of.
MapQuest, Vistaprint, and their suppliers make no representations or warranties about content, road conditions, route usability, or speed. If you have to shout to make yourself heard by someone standing within 1 to 1.5 meters of you, the noise level is considered excessive and it will exacerbate your tinnitus. We hypothesized that tinnitus relief with Clear Tinnitus reflects improvement in the sensory component of the tinnitus complaint by controlling the factor of aeration of the middle ears and improving eustachian tube function. The designers of Clear Tinnitus have claimed that this blend of homeopathic remedies and herbal medicine, when taken on a daily basis for 3 months, has resulted in significant tinnitus relief [5].
We used quantitative electroencephalography (QEEG) as a monitor at the start and conclusion of the study to identify patterns of electrical activity of brain function hypothesized to reflect tinnitus relief [16].
We performed ultra-highfrequency audiometry using the Tonndorf audiometer for electrical high-frequency audiometry and the Beltone 2000 audiometer for air-conduction high-frequency audiometry. We correlated the physical examination of the tympanic membrane with the tympanometry result.
We used within-group repeated-measures analysis of variance (RMANOVA) to assess the differences in the TAI, the TST, the TII, the THI, the stress test, and the depression scale. The remaining patient dropped out after 1 week in the study because of difficulty in adhering to the regimen, even though subjectively reporting tinnitus relief through the use of Clear Tinnitus. For 10 of the 11 patients who completed the study, tinnitus location was unchanged; the remaining patient had no tinnitus at the end of the study.


Of the remaining three, one with type IV went to type I for both ears; the other two with type IV in both ears went from type IV to type I for one ear and remained at type IV for the other. Two patients with a borderline MEP at the outset that changed to normal reported a positive tinnitus relief outcome, and a single patient with an originally abnormal MEP that changed to borderline also reported positive tinnitus relief.
Comparison QEEGs of the seven responders and four nonresponders demonstrated similar patterns. The TST indicated a mean change before and after the study of -4.18, which was not statistically significant. Owing to small sample size, statistical analysis was limited to univariate and repeated-measures statistical procedures.
The correlation of the nonresponders (n = 4) and the responders with the recorded fluctuation in MEP is considered significant. The tympanogram findings of improvement in MEP function in responders is considered to support the hypothesis that improvement in MEP underlies Clear Tinnitus resultant efficacy for tinnitus relief by influencing the transduction mechanism of the middle and inner ear. The similarity of the mean delta QEEG response in the 11 patients and the 7 individual responders and the relative lack of correlation of the delta response to the remaining theta, alpha, and beta find clinical support for consideration that the action of the Clear Tinnitus preparation is predominantly its peripheral MEP effect, with secondary tinnitus relief as reported by the responders, and not specifically its effect on the tinnitus.
No significance appeared in comparing the results of responders to those of nonresponders but, again, this could be owing to the small sample size when separating the patients into independent groups. If you want to get rid of tinnitus fast and naturally without any side effect, then you should read this writing. In addition, garlic has antibacterial properties, which will help you get rid of almost infections, which can be contributing to your ear problem. Moreover, this oil may boost your immune system in order to protect the body against further infections as well as eliminate the buildup of earwax. Moreover, aspirin-like properties found in ginger will help you relieve the pain accompanied with tinnitus. If you have any question, or you know other natural home remedies for tinnitus or the ringing in the ears, please leave them below.
We examined the relationship between worry and self-perceived anxiety and depressive symptoms and handicap in 54 outpatients with chronic tinnitus and sensorineural hearing loss who had been previously recruited for a randomized double-blind study on the efficacy of transmeatal low-level laser therapy for tinnitus. The observation group 2 was treated with electroacupuncture at the same acupoints as those point irradiation in observation group 1. Although many studies have indicated a positive effect of low-level laser therapy (LLLT) on neural cell survival, there has been no study on the effects of LLLT on cochlear hair cells.
The method proved less efficacious for the management of long-standing hearing impairement and chronic loss of hearing, but it can be used to prevent the development of these conditions. A decrease of one scale point, regarding the loudness, duration and degree of annoyance of tinnitus, was accepted to represent an improvement. However, light-dosimetric studies on human temporal bones demonstrated that controlled application of laserlight to the human cochlea depends on defined radiator position within the external auditory meatus. The hearing capacity of the patients was improved in all frequency sectors (average value = 20.6%). This holds good for both the air and the bone conduction.If one takes into consideration the energy quantity (j) transmitted in order to reach these results, it is obvious that the eldest age group needs the largest quantity of transfered energy. For an estimation of the corresponding space irradiance in an intact cochlea, correction factors have been calculated by a Monte Carlo procedure on the basis of experimentally determined optical properties of skull bone.
For an irradiation of the mastoid, the light transmission within the cochlea is 10(3) to 10(5) times smaller compared with an irradiation of the tympanic membrane and is extremely variable for different specimens. Mastoidal irradiation leads to therapeutically insufficient light doses within reasonable treatment times, whereas transmeatal irradiation is recommendable. Low level lasers have been used to treat tinnitus patients with reasonable success, if sufficient energy and suitable treatment technique is used. The clinical study was performed with 30 patients suffering from chronic permanent tinnitus. The active or placebo laser treatment was administered trans-meatally once a week for 6 minutes. According to literature, fifteen per cent of entire population have experienced at least a tinitus episode some time, its incidence and severity rising with age up to approx.
On the other hand, this selection led to a more pure evaluation of the role of LLLT in the treatment of tinnitus, leaving out both a possible cause and a corresponding treatment. At the start and conclusion of the study, we performed QEEG testing using a Neurosearch 24 Instrument (Lexicor Medical Technology, Inc., Colorado) to measure objectively a spectral analysis of electrical activity of the brain. Type I masking curves are considered consistent with peripheral tinnitus and type IV with central tinnitus (Table 2). Of the seven responders, two reported no MEP change; one nonresponder also reported no MEP change.
At the conclusion of the study, 10 of the 11 patients had normal to borderline MEPs, and 1 had an abnormal MEP. No significant main effects arose for either changes in the number of abnormal QEEGs over time or the interaction of the EEG band by time. In a comparison of the change in response between responders (n = 7) and nonresponders (n = 4), we observed no significant differences. The THI indicated a mean pre- and post-study change of -11.73, which was not considered to be statistically significant. In both groups, MEP fluctuation or maintenance of normal pressure was and was not (respectively) correlated with positive tinnitus relief. Significant for this study is the correlation of -100 mm H2O as abnormal with the tympanogram results: Of the seven patients who reported subjective improvement, three went from type C tympanograms to type A. In general, it was hypothesized for this study that an alteration in an original dyssynchronous auditory signal from the peripheral auditory system, resulting from improvement in MEP, and its subsequent effect on the transduction processes of the middle and inner ear, when received by the thalamus, would be synchronized at brain cortex in the form of different brain rhythms. A reduction in the number of significant delta band recordings occurred over the time course of the study; however, the reduction was not statistically significant. We recommend a larger patient sample over a longer interval of Clear Tinnitus treatment to determine whether the delta rhythm data, although not significant at this time, may reflect a trend of a positive response to therapy when correlated with the remaining theta, alpha and beta frequencies.
For the tinnitus outcome tests that were statistically significant, the key question to be asked is whether the reported tinnitus relief is clinically significant to the patients. For still others, a combination of these factors or other issues are the goals of treatment. Frequency-specific hearing levels were measured before the noise exposure and also after the 1st, 3rd to 5th, 8th to 10th and 12th irradiations. Therefore, the aim of this study was to elucidate the effects of LLLT on hair cell survival following gentamicin exposure in organotypic cultures of the cochlea of rats. The mean VAS score reduction was not statistically significant between male and female patients (p = 0.23).
Moreover, a hearing test was performed before and after therapy and results were reported as the pure tone average of 500-, 1000-, 2000-, and 3000-Hz frequencies. This feasibility study first presents a laser application system enabling dose-controlled transmeatal cochlear laser-irradiation (TCL), as well as preliminary clinical results in patients with chronic cochlear tinnitus. Patients with hearing aids were advised to reduce the adjustments according to their improving hearing quality. It has to be emphasized, though, that once again the most difficult patient group (average duration of the disease 14.5 years) needed the largest quantity of transfered energy. Further studies are mandatory for development of clinical devices for transmeatal irradiation of the cochlea. Only 26% of the patients reported improved duration, but 58% had  reductiont of loudness and 55% reduced annoyance. This study brings an additional overview of the role of LLLT (Low Level Laser Therapy) in the treatment. Audiogram provides only for numeric range of perception of frequency of sounds, however it does not give us an objective evaluation of quality of hearing.
We placed an electrode array (consisting of 19 electrodes) on the scalp in a standard international 10-20 pattern [16].
The clinical significance to the patient of reported and recorded tinnitus relief was positive in five patients. Of the remaining three, one with type IV went to type I for both ears, and the other two who were type IV for both ears went from IV to I for one ear and remained type IV for the other. Alterations in the brain rhythms may reflect the efficacy of the Clear Tinnitus for tinnitus relief.
The QEEG data suggest that a slightly larger sample size might have changed the outcome of this analysis.
Of interest was the response of the seven patients who reported tinnitus relief: When asked whether their relief was "significant," the response was negative for two and positive for five. In any case , the outcome results of this study emphasizes the need for a battery of outcome measures to be included in the evaluation of therapeutic modalities attempting tinnitus relief [13]. The writing is a collection of safe and natural solutions to remove the ringing in the ears from reliable sources.
For the psychoacoustic tinnitus measures, we considered the loudness match and the minimum masking level. The cochlea cultures were then divided into a control group (n=8), a laser-only group (n=8), a gentamicin-only group (n=8) and a gentamicin plus laser group (n=7).
The improvement of rheoencephalographic characteristics was documented in the patients of all groups but was especially pronounced in group 1.
The novel laser TCL-system, consisting of four diode lasers (lambda=635 nm-830 nm) and a new specific head-set applicator, was developed on the basis of dosimetric data from a former light-dosimetric study.
The average improvement was 22.84 dB for 74 long time follow up observations (4-6 months after therapy).
There was a close correlation between the improvement of the hearing capacity and the age of the patients and the duration of their disease. The authors conclude: ”Laser therapy seemed to be worth trying on patients with intractable tinnitus”.
A questionnaire was administered to evaluate the loudness, duration, quality, and annoyance of tinnitus before and after irradiation. Our results enable us to pinpoint laser as the leading element in the overall therapy of tinnitus. Furthermore, the patients do not see the main improvement in a wider range of frequency of sounds, this remains usually on a similar level, but the main benefit is the absence of the additional burdening sound caused by tinnitus.
We employed a descriptive data analysis method across dimensions of risk to evaluate a base of multidimensional evidence and establish support for our hypothesis. At the conclusion of the 12-week period, we repeated all the audiological tests administered on the initial visit.
The analysis compared changes over time in the number of abnormal recordings from the main locations of the scalp recordings (frontal, temporal, parietal, and occipital).
This difference, when analyzed by a general linear RMANOVA, was not significant owing to the low power and small sample size. Type I masking curves are considered consistent with peripheral tinnitus and type IV with central tinnitus. Of the four who did not report subjective improvement, three went from type C to type A (one in both ears, the other two in one ear). Efficacy of treatment was hypothesized to be reflected by a reduction in the delta or beta frequencies (or both), a minimal or unchanged theta frequency, and an increase in the alpha frequency.
The reduction in the delta response was accompanied by a small increase in the theta response in one patient (not statistically significant at this time).
Such a battery of outcome measures should be completed at least at the start and end of the study.
However, it is not intended to give medical advice and it is solely for the informational purpose. Compared to initial hearing levels at all frequencies, thresholds increased markedly after noise exposure. It is concluded that the proposed method significantly increases the efficiency of treatment of chronic sensorineural hearing loss. In a preliminary clinical study, the TCL-system was applied to 35 patients with chronic tinnitus and sensorineural hearing loss. Until now there hasn’t been any known potent therapeutic method improving hyperacusis. In conclusion it can be stated that if LLLT is administered in sufficiently high dosages to the inner ear (cochlea), it is possible to obtain and document significant biostimulative effects. Therefore the patients can better analyze sounds in general, their hearing is “refreshed” as they usually describe the result of the therapy. A medicalaudiological tinnitus patient protocol completed by each patient identified the clinical type of tinnitus as predominantly cochlear, with a central and middle-ear component bilaterally.
We used the RMANOVA to test changes in the number of abnormal recordings for the 12-week period of the study for the EEG band frequencies delta, theta, alpha, and beta.
This lack of significance, due to low power (.336), estimates that there was approximately a 66% chance of missing a significant result for the change in the number of significant recordings over time. We found no statistically or clinically significant correlation of masking curve type to outcomes. Nonresponders with normal MEP and responders with no MEP change provide an inconsistency surrounding the hypothesis. Furthermore, the duration of clinical studies evaluating therapeutic modalities for tinnitus relief should be long-term (at least 6-12 months).
This suggests the usefulness of worry assessment when managing chronic tinnitus in clinical practice. After the 12th irradiation, hearing threshold was significantly lower for the NL ears compared to the N ears. The chronic symptoms persisted after standard therapeutic procedures for at least six months, while retrocochlear or middle-ear pathologies have been ruled out. In some cases laser therapy alone will produce astonishing results, in others it has to be combined with traditional occlusal stabilisation procedures.
However, 40% of the patients reported a slight to significant attenuation of the tinnitus loudness of the treated ear.
In one patient who received active laser treatment, acute hearing deterioration occurred after the third irradiation.
We identified fluctuation in middle-ear pressure (MEP) via patients' clinical history, supported by physical examination and established with tympanometry, as a factor influencing the clinical course of the tinnitus in each patient. Early therapeutic interventions for reducing proneness to worry may facilitate better adaptation to tinnitus. When observed using an electron microscope, the number of hair cells in the middle turn of the NL ears was significantly larger than that of the N ears. The gentamicin groups were exposed to 1 mM gentamicin for 48 h and allowed to recover (gentamicin-only group) or allowed to recover with daily irradiation (gentamicin plus laser group). The pulsed electromagnetic field applicator generated a magnetic field of a maximum of 100 µT and it was placed behind the ear, over the area of the mastoid bone. Lutz Wilden of Bad Fussing, Germany reported on his 6 years of experience at a recent lecture before the members of the Swedish Laser Medical Society (Stockholm, May 1998).
It is important for doctors to be aware of this subgroup of tinnitus patients since traditional therapies, and even laser therapy of the inner ears, will be ineffective if the CMD is not diagnosed and treated. Transmeatal low-power laser irradiation with 60 mW is not effective for the treatment of tinnitus. No significant relationship appeared with the number of reductions of significant QEEG recordings over time and MMLs or LDLs. In the patients reporting tinnitus relief when a tympanogram type A was identified at the start of the study and remained unchanged at the conclusion of the study, the tinnitus relief correlated more with the improvement in appearance of the tympanic membrane and the reported reduced negative MEP than with the tympanogram type (see Table 1).
Our findings suggest that low-level laser irradiation promotes recovery of hearing thresholds after acute acoustic trauma. For evaluation of laser-induced effects complete otolaryngologic examinations with audiometry, tinnitus masking and matching, and a tinnitus-self-assessment were performed before, during and after the laser-irradiation.
Before every therapy series with LLLL the patients actual hearing capacity (air and bone conductions) was examined by audiometry.
ROS were measured and controlled by administrating different sorts of antioxidants such as Ginkgo biloba. The number of hair cells was significantly larger in the gentamicin plus laser group than in the gentamicin-only group. The first clinical use of the TCL-system has been well tolerated without side-effects and produced no observable damage to the external, middle or inner ear.
At the end of each therapy series their hearing capacity was examined by the same method for a second time.
The number of hair cells was larger in the laser-only group than in the control group, but the difference did not reach statistical significance.
Descriptive data analysis failed to detect any trends in a change in response with audiometric tests across the hearing spectrum; thus, we could derive no coefficients of hearing change. These results suggest that LLLT may promote hair cell survival following gentamicin damage in the cochlea. After a follow-up period of six months tinnitus loudness was attenuated in 13 of 35 irradiated patients, while two of 35 patients reported their tinnitus as totally absent.
Total dosage 2000-4000 (sic) joules per treatment (60 minutes per session, 30 minutes per ear). This is the first study in the literature that has demonstrated the beneficial effect of LLLT on the recovery of cochlear hair cells. C) The hearing capacity of the patients was ameliorated in all frequency sectors (average value = 20.6 %). Doses may seem very high, but the thick bone behind the ear absorbs about 95% of the energy before reaching the inner ear.
The Feldmann masking curve comparison at the start and end of the study showed no significant change in the 11 patients. Further investigations by large double-blind placebo-controlled studies are mandatory for clinical evaluation of the presented TCL-system and its therapeutic effectiveness in acute and chronic cochlear dysfunction.
There was no significant alteration in the minimum masking levels or loudness discomfort levels before and after the study.
There was a close (and biologically plausible) correlation as far as the amelioration of the hearing capacity and the age of the patients and the duration of their disease were concerned; this correlation was the higher, the more energy was transfered on the whole.
Quantitative electroencephalography analysis revealed a marked difference in the number of significant abnormal recordings between the different frequency bands, with the delta band significantly higher than the theta, alpha, and beta bands for both the overall cohort of patients (n = 11) and those reporting tinnitus relief (n = 7). The tinnitus outcome questionnaires-the tinnitus intensity index, the tinnitus annoyance index, and the tinnitus reaction questionnaire- revealed a significant difference for the patients (7 of 11) obtaining tinnitus relief. Results of the tinnitus stress test , the tinnitus handicap index, and the measurement of depression scale before and after the study were not statistically significant.
Conclusions: Patients who completed the study demonstrated with tympanometry a statistical and clinical significance in MEP improvement or maintenance of MEP (or both). Patients with tinnitus of the severe disabling type selected for this study and responding to Clear Tinnitus reported tinnitus relief accompanied by improvement in or maintenance of MEP of the middle ears. The statistical and clinical significance of Clear Tinnitus for establishing tinnitus relief remains to be established with a larger cohort of tinnitus patients.




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