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Send Home Our method Usage examples Index Contact StatisticsWe do not evaluate or guarantee the accuracy of any content in this site. This Overview Vitamins gives information about vitamins which are are an essential part of our diet. Dietary sources of B6 are similar to B12 and also include avocado, herring, salmon, sunflower seeds and walnuts.
Food sources: liver, leafy green vegetables, intestinal bacteria, whole grains, fruits and beans. Citrus Fruit is an excellent source of Vitamin C, efficient for warding off colds and flu, as it does wonders for the immune systeme. This site is for information only and is not intended to replace the advice of a health professional who can examine you before making a diagnosis. If you want to support, without it costing you a cent, shop at AMAZON st the link below. Methyl-Life’s product, B-Methylated-II is a lozenge meant to be taken sublingually (or absorbed through the mouth).  It has the most biologically active forms of B-9 Methylfolate (often denoted as L-MTHF, 5-MTHF, or L-5-MTHF) and B-12 (as Methylcobalamin) that you can get.
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Vitamin B12 is essential for so many primary biological functions that are necessary for survival- your nervous system, hormonal balance, cognitive functioning, metabolism, cell formation, to name just a few. But until you learn to recognize the earliest symptoms of vitamin B12 deficiency, you’re at risk for pernicious anemia and all the damage that it can cause throughout your system. Here are 99 ailments that often occur in people with moderate to severe vitamin B12 deficiency, including comorbid conditions and direct symptoms.
Vitamin B12 is one of the most important nutrients for the body- and the hardest to digest, for many people.
Vitamin B12 is essential for survival; it is involved in some of the most vital processes that take place in the body. Vitamin B12 also aids in converting carbohydrates into necessary energy, ensuring that you have plenty of stamina and mental focus during the day.
Vitamin B12 enhances your nervous system functioning by helping to maintain myelin, a fatty coating that surrounds each individual nerve cell. While it’s possible to find vegan products that are fortified with vitamins such as B12, these are not natural forms of the vitamin, and don’t provide the maximum amount needed to maintain healthy vitamin B12 levels.
To prevent deficiency, vegans and vegetarians are recommended to take vitamin B12 supplements on a regular basis. If your vitamin B12 levels have been low for a very long period of time, you may have pernicious anemia, a type of megaloblastic anemia that occurs when people are unable to produce intrinsic factor. Pernicious anemia can result from an autoimmune disorder or it can occur as a result of damage to the stomach lining (gastritis). If you have pernicious anemia, then you can’t get enough vitamin B12 from swallowing pills or other dietary supplements. By the time you start to notice the signs of vitamin B12 deficiency, you are already on a dangerous decline, as it takes years for the symptoms to manifest themselves. The recommended daily allowance for vitamin B12 consumption for healthy people who don’t have a deficiency is a scant 2 or 3 micrograms per day. If you are unable to produce intrinsic factor, then you can only digest about 1% of all the vitamin B12 you get from foods, pills, or other supplements. So, to get the amount you need to keep your B12 levels at a normal rate, you need to take about 100 times the amount any other person would need to stay healthy.
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Thousands of people in the US suffer from vitamin B12 deficiency; some questions people often have are, “How did my B12 levels get so low? Vitamin B12 helps to keep your nervous system functioning normally, as it sustains myelin, a fatty coating that protects your nerve cells and enhances intercellular communication. Vitamin B12 also supports a healthy metabolism in converting fuels into much-needed energy and synthesizing DNA. Vitamin B12 is required for proper red blood cell formation, as it helps to maintain a healthy level of normal-sized functioning red blood cells for oxygen transportation to your brain, organs, and cell tissues throughout your body. Vitamin B12 helps to control levels of homocysteine, a hormone that has been linked with increased risk for heart attack, stroke, and Alzheimer’s disease. The richest sources of vitamin B12 are animal-based foods such as meat, poultry, seafood, milk, and eggs.
Still, if you have vitamin B12 malabsorption, a common risk factor for vitamin B12 deficiency, then you must take supplemental forms of vitamin B12 in order to prevent pernicious anemia. It’s always good to test for low vitamin B12, but the best way to know if you’re getting enough is by paying close attention to telltale symptoms of severe vitamin B12 deficiency. Since vitamin B12 depletion happens slowly, you may not realize you’re experiencing a deficiency until you start to notice yourself always feeling tired, depressed, or just generally slower than usual. If you keep a vegan diet, or refrain from eating many animal-based foods, then you are a risk factor for vitamin B12 deficiency, simply because there are no vegetable-based foods that supply sufficient amounts of vitamin B12 to prevent anemia.
If you’re not a vegan, and you have no chronic illnesses, then you may still be at risk, as there are a number of medications that interfere with your ability to digest vitamin B12 naturally from foods, resulting in vitamin B12 malabsorption- a major cause of vitamin B12 depletion that often slips off the radar. If you have had a gastric bypass for weight loss, then you may be at risk for vitamin B12 deficiency.
Peripheral neuropathy (nerve damage) from vitamin B12 deficiency is one of many ailments that occur with long-term alcohol abuse. If you have any other autoimmune disorder, such as celiac disease, fibromyalgia, or lupus, then your risk for autoimmune vitamin B12 deficiency is higher than normal. Finally, any kind of damage to your stomach, intestines, or esophagus can interfere with your ability to absorb vitamin B12, increasing your chance for pernicious anemia.
Illnesses that cause frequent vomiting, such as migraines, fibromyalgia, and Crohn’s, are linked with comorbid vitamin B12 deficiency. As we age, our bodies tend to slow down; that includes a reduction in the amount of digestive enzymes we produce- proteins needed to absorb vitamin B12.
For that reason, health experts recommend strict vitamin B12 supplementation for all senior citizens, even if they don’t think they need it, as the symptom don’t manifest themselves until vitamin B12 levels reach a dangerous low. Don’t ignore symptoms of vitamin B12 deficiency, even if you are “healthy” and “normal.” Plenty of people have vitamin B12 deficiency, and don’t even know it- not until they start experiencing severe ailments. Get a blood test, take your vitamin B12, and keep track of your mood and energy levels each day; this will be your best Richter scale for determining how much vitamin B12 you need in order to prevent anemia and maintain good health.
Signs and symptoms of menopause are sometimes associated with vitamin B12 deficiency, or malabsorption of vitamin B12 from the foods you eat.

Menopause is a phase that may stretch for several years; many women experience their first signs of perimenopause (early menopause) in their 40s, while still menstruating.
Vitamin B12 deficiency is difficult to catch and treat, as the symptoms are masked by conditions such as menopause, clinical depression, hypothyroidism, or hypoglycemia- all of which cause ailments that are strikingly similar to the ones you experience when your vitamin B12 levels drop to a dangerous low, either from malabsorption issues or change in diet. For that reason, premenopausal women and females already experiencing menopause are advised to test often for vitamin B12 deficiency, and recognize the symptoms, before their B12 levels drop to a dangerous low. Untreated, vitamin B12 deficiency from pernicious anemia can lead to neurological disorders, chronic fatigue, mood problems, and increased risk for heart attack and stroke. That’s because vitamin B12 is essential for so many biological functions necessary for good health- reproduction, nervous system functioning, cognitive integrity, and metabolic energy. So, when vitamin B12 levels plummet, you begin to experience a variety of health problems that affect all parts of your body, including those already ailing from symptoms of menopause. The Linus Pauling Institute recommends 100 to 400 mcg per day of supplemental vitamin B-12 orally if you’re older than 50, an age that includes many menopausal women.
Did you have vitamin B12 deficiency or pernicious anemia during your pregnancy?  If you’re currently breastfeeding your baby, it’s crucial that you continue to check your vitamin B12 (cobalamin) levels.  Here’s the scoop on taking care of baby with vitamin B12 deficiency. Even after giving birth, if you breastfeed and have vitamin B12 deficiency at the same time, then your baby is also at high risk for getting vitamin B12 deficiency, regardless of how often you nurse.
Many studies have been conducted documenting the dangers of exclusive breastfeeding while suffering from vitamin B12 deficiency. In them, researchers noted some disturbing symptoms of vitamin B12 deficiency in infants, such as failure to thrive.
Most of these symptoms were alleviated only after B12 levels were restored to normal through immediate supplementation of vitamin B12. The decision to breastfeed or bottle-feed is a personal decision, but vitamin B12 deficiency should not be the deal breaker.
You can rest assured that your baby is getting all the nourishment it needs, as long as you continue to maintain healthy vitamin B12 levels.
Remember, it’s not possible to take too much vitamin B12, as there are no harmful side effects to taking large doses of vitamin B12. Not having enough vitamin B12 in your blood supply, however, can be detrimental, even deadly. If you have pernicious anemia, did you find out only after years of suffering, or were you warned about it from family members?
Are constant eyelid twitching and eye spasms driving you batty?  Myokymia might be a sign of pernicious anemia caused by low vitamin B12 levels.  Learn how to stop eye twitching by halting vitamin B12 deficiency in its tracks. It can also occur on your face- hemifacial spasms are muscular twitches that begin on one side of your face, usually the eye.  Over time, hemifacial spasms can expand to include the rest of your face, on one side. Myokymia is a type of nerve damage called trigeminal neuralgia.  When your eyelid keeps twitching out of control, it is because the nerves that control the opening and closing of your eyes have been damaged.
Causes of eye twitching may include stress, excessive alcohol usage, and staring at a computer screen for long periods of time.  Eye spasms can also be a reaction to caffeine, or may signify low levels of cobalamin- vitamin B12. Vitamin B12 benefits include red blood cell production, protection of the nervous system’s myelin sheathe, cognitive functioning, DNA synthesis, and lowered homocysteine levels. If your body does not store adequate amounts of vitamin B12, you may get B12 deficiency, and ultimately severe pernicious anemia, a type of megaloblastic anemia blood disease. Pernicious anemia symptoms include severe nerve damage, such as eyelid spasms caused by myokymia.  Lower eyelid twitches are most common with vitamin B12 deficiency patients. If you suspect that you have vitamin B12 deficiency, then consult your physician and request a blood test for B12 levels.
If you’re planning a pregnancy, you might want to check your B12 levels- numerous reports link vitamin B12 deficiency during pregnancy with miscarriage, spontaneous abortion, and other fertility problems.  B12 deficiency anemia- pernicious anemia- makes it harder for women to conceive, as well as for men to produce fertile sperm. All women who participated in the study suffered severe vitamin B12 deficiency anemia in addition to low fertility- Four had been trying unsuccessfully to conceive for two to eight years, and eleven experienced repeated miscarriages and spontaneous abortions. If fetal loss were to continue despite elevating B12 levels, it would prove that infertility was unrelated to B12 deficiency or pernicious anemia symptoms.
Instead, result showed that ten out of the fourteen test subjects experienced favorable results from vitamin B12 supplements. The results can be found in this study on vitamin B12 and fertility. Bennett notes that B12 deficiency, combined with folate deficiency, led to thrombophilia (blood clotting) in seven of the women studied, thus increasing their risk for miscarriage. He believes that taking large amounts of folic acid, a nutrient prescribed to women of childbearing age, often masks B12 deficiency symptoms, making it harder to diagnose and treat. Vitamin B12 benefits your body in many ways- it helps to produce red blood cells, promotes DNA synthesis, guards the nervous system’s myelin sheath, maintains cognitive functioning, lowers homocysteine levels, and supports metabolism. Left untreated, vitamin B12 deficiency can cause severe nerve damage, cognitive disorders, and increased risk for heart disease and stroke. Since vitamin B12 interacts with so many different areas of the body, many seemingly unrelated symptoms indicate vitamin B12 deficiency.  Pernicious anemia masks itself as mood disorders, diabetes, celiac disease, fibromyalgia, hypothyroid, and other chronic conditions.
The elderly need to increase their intake of vitamin B12, in order to avoid memory loss from vitamin B12 deficiency.  Brain loss caused by Alzheimer’s disease and other forms of dementia is sometimes a part of the aging process, but by getting enough vitamin B12 in your blood, you can prevent suffering the symptoms of vitamin B12 deficiency. A 2011 study that focused on 121 community-dwelling participants of the Chicago Health and Aging Project found a strong correlation between vitamin B12 deficiency and memory loss. They found a direct relationship between low levels of vitamin B12, reduced brain volume, and decreased cognitive skills, such as loss of short-term memory. Scientists noted poorer memory skills, slower thinking processes, and impaired comprehension skills as attributes associated with elevated methylmalonate levels- an indicator of vitamin B12 deficiency.
Also considered were plasma homocysteine levels, which scientists also connected with loss of brain mass.  High levels of homocysteine are common in vitamin B12 deficiency.
Scientists concluded that methylmalonate, an indicator of vitamin B12 deficiency, has a direct impact on brain volume, and that vitamin B12 has multiple benefits on brain chemistry beyond just memory skills.
In 2008, a UK study conducted by the University of Oxford produced similar results; namely, that vitamin B12 deficiency is a likely cause of brain atrophy, dementia, and short-term memory loss among the elderly. Eating plenty of foods rich in vitamin B12 is always a good idea; such foods include protein sources like beef, chicken, fish, eggs, milk, and cheese. Unless blood tests indicate healthy levels of vitamin B12, senior citizens must supplement with vitamin B-12 (cobalamin) with a routine prescribed B12 shot in order to avoid the symptoms of vitamin B12 deficiency. It isn’t just the elderly who should be concerned with memory loss- short-term memory loss is one of many symptoms of vitamin B12 deficiency, regardless of age. Long-term exposure to vitamin B12 deficiency could result in severe neurological damage, pernicious anemia, increased risk for heart attack, stroke, and osteoporosis. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. Although they are found in small quantities in various foods, they are essential for our metabolism and for life. They are the ‘already converted’ forms of the vitamins that are immediately ready for the body’s cells to use directly. It also allows for more flexible dosing, for example, one family member may only need one pill per day and another may require 3 pills per day. And consider reviewing our Methylation Protocol page as one example of how someone could start taking the active methylation nutrients. In the chemistry world, L stands for the “Left” isomer, which is the same as the “(6S)” isomer – the terms are synonyms (and this naming convention is used interchangeably by various companies in the industry). Methyl-Life cannot be held liable for adverse reactions or negative side effects that you think are the result of one of our products. We also recommend you read through our dosage and methylation protocol pages and consider starting with a lower dose product to ensure you tolerate the ingredients well before increasing your strength to a higher dose product. Just let us know you plan to return the product by emailing us using the Contact Us form (please include the tracking information so we can be on the lookout for the package). Our supplements are cost-effective and made from top quality ingredients, selected after extensive research.

If you are a doctor or a business, just click below to register with us for a wholesale account. If you have any of the most common symptoms- fatigue, depression, memory loss, painful “pins and needles” in the hands and feet- then you may be surprised to learn that there’s a lot more to pernicious anemia than beats the eye. It’s no wonder that when vitamin B12 levels are even marginally low, the results can range from annoying and disturbing to debilitating and catastrophic. Today, thanks to vitamin B12 supplementation, we are able to maintain normal levels of vitamin B12, even in spite of vitamin B12 malabsorption from autoimmune disorders and gastrointestinal illnesses.
A water-based B vitamin, cobalamin is essential for the nervous system, blood cells, and for DNA. Without enough vitamin B12 in your system, your body starts producing overlarge irregular-shaped blood cells that cannot function properly, resulting in a depletion of oxygen-carrying hemoglobin.
It’s not a simple matter of eating plenty of foods the contain vitamin B12, such as beef, chicken, seafood, and dairy products.
Only supplementation with a highly-absorbable form of vitamin B12 that enters directly into the blood stream can reverse the symptoms of severe vitamin B12 deficiency. Also, blood tests for vitamin B12 deficiency don’t give you ample warning to up your vitamin B12 intake, as they only test for extremely low levels of vitamin B12, and aren’t always even accurate in such screenings. Why then do most vitamin B12 supplements contain a whopping 1,000mcg of vitamin B12 in one weekly dose? I eat healthy and I don’t have any chronic illnesses, so how did I become anemic?” That’s a complex question to answer, because there are many ways that people become gradually deficient in this crucial B vitamin. Also, gastrointestinal surgeries recommended for treating Crohn’s disease, such as removal of the ileum, necessitate frequent vitamin B12 supplementation in order to prevent pernicious anemia.
Autoimmune intrinsic factor dysfunction causes your body to attack intrinsic factor, a digestive enzyme that bonds to vitamin B12 and helps to distribute it into your blood supply. If you suffer from chronic heartburn, gas, and bloating, then that may be an important clue in determining why you often feel tired, anxious, or agitated. For many healthy individuals over 60, signs of depression and forgetfulness are often discounted as the first symptoms of senility, without even checking vitamin B12 levels. To boost energy, sleep better, and balance your mood, it’s important to take extra doses of vitamin B12 during the menopause years.
During the early stages, you experience fluctuation hormone levels that cause mood swings, headaches, hot flashes, memory loss, and brain fog. And it’s easy to understand why, especially when you consider that the most common symptoms- fatigue, achiness, poor memory, dizziness, and depression- are present in both vitamin B12 deficiency anemia and the many stages of menopause. Once you start taking vitamin B12, you will notice a decrease in pernicious anemia symptoms immediately, and total reversal of symptoms by the time your B12 levels return to normal.
Michael Bennett, hematologist of the Ha’Emek Medical Center in Afula, Israel, implemented vitamin B12 supplementation to see if it would have any effect on their ability to conceive and have healthy pregnancies.
Bennett attributes raised homocysteine levels, a symptom of vitamin B12 deficiency, with repeated fetal loss, and over time, ovulation disorder. The good news is that you don’t have to worry too much about being deficient in it as long as you are eating a standard diet.
A wide variety of neuropsychiatric abnormalities is also seen in vitamin b 12 deficiency and appears to be due to an undefined defect involving myelin synthesis.
As they cannot be produced naturally by our bodies, our main source is through food and in some cases medication (i.e.
It also helps maintain the nervous system, involved in DNA synthesis and prevents anemia along with folic acid (see Vitamin B9). It is also commonly known for building up immune systems so that we can respond appropriately to infection.
The length of your telomeres affects your lifespan and short telomeres can mean that you have less protection from serious diseases. The lozenge is most effective when absorbed through the mouth because B12 does not absorb well via the gut.
Before you purchase, check out our dosage information to learn more about what some doctors recommend. You can learn more about his protocol by watching parts 3 & 4 of his video seminar, or downloading his protocol document found on the A Doctor Explains page. In the case of methylfolate, that L or (6S) isomer is the active isomer of 5-MTHF that the body can actually use.
If you return three unopened bottles from a 4-pack purchase, you will receive a full refund minus the cost of one bottle charged at full price. The ingredients we use are the most bioactive, so they can bypass genetic mutations and allow your body to absorb and use the nutrients right away. This blog is dedicated to providing up to date research, news and resources pertaining to vitamin B12, general health information surrounding the benefits of vitamin B12. Yet an increasing number of people don’t get enough vitamin B12 from food, and as a result feel fatigued and disoriented from pernicious anemia. To complete the digestion process, your body uses a digestive enzyme called intrinsic factor, which bonds to the vitamin and escorts it through your digestive system. People with autoimmune pernicious anemia cannot get vitamin B12 from foods, regardless of diet, and must use supplemental forms of vitamin B12 for survival. Recently, elderly people with hearing loss have been reported to be much more likely to be folic acid deficient than healthy elderly people. A variety of prescription drugs including antacids, some anticancer drugs, and anticonvulsants interfere with folic acid. A study of seniors between the ages of 60 and 75 indicated that when the telomeres were short, the risk of death from heart disease was 300% higher and the risk of death from infectious diseases was 800% higher. And review our suggested methylation protocol as a potential step by step guide to one dosing option. The L-5-MTHF [or (6S)-5-MTHF] enzyme is bound to a salt molecule and in the case of one ingredient (Magnafolate-C™), it’s bound to a calcium salt molecule for delivery to the body, and in the case of another ingredient (Quatrefolic®), it’s bound to a glucosamine salt molecule for delivery to the body. After we receive your returned item, we will process your full refund within 10 business days and send you an email indicating your refund has been complete.
Learn from, and contribute to information on B12, vitamin B12 and other connected subjects. Here we will outline some of the common reasons for low B12 levels, and how to spot if you might be short on them.OverviewSome of the big name vitamins seem to get all of the media and mainstream attention.
To learn more about the different types of methylfolate, its history, potency levels and stability details, visit our Methylfolate Types page. Be aware that depending upon your institution, this may not be reflected in your account status for a few days. Vitamins like C, D, and A are always making headlines for their antioxidant properties and feel good effects on the body. Furthermore, this type of deficiency will increase the risk of infection (due to weak immune system), extreme fatigue and deterioration of the gums. But the B vitamins are finally getting their moment in the sun, and more and more people are realizing the health benefits of making sure they’re getting enough of them.Key ConcernsIf you’re not getting enough Vitamin B-12 you’ll be setting yourself up for complications that can arise if this goes on for too long. You could be leaving yourself open to decreased brain size and function due to brain shrinkage with age, and you’ll be at greater risk of various diseases of the heart. You’ll also be more susceptible to different cancers, as B12 has been directly related to prevention and treatment of these conditions.

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