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Author: admin, 06.02.2014. Category: Tinnitus Causes And Cures

Chronic kidney disease (CKD) is a progressive loss of renal function over the course of several months or years.
Chronic kidney disease has no specific symptoms at first and can only be identified as a spike in serum creatinine or protein in the urine.
Chronic pancreatitis can cause tummy (abdominal) pain, poor digestion, diabetes and other complications. Bronchitis is the inflammation of the bronchi, the main air passages to the lungs, it generally follows a viral respiratory infection. Bronchitis is a respiratory disease in which the mucus membrane in the lungs' bronchial passages becomes inflamed.
As the irritated membrane swells and grows thicker, it narrows or shuts off the tiny airways in the lungs, resulting in coughing spells that may be accompanied by phlegm and breathlessness.
The disease comes in two forms: acute (lasting from one to three weeks) and chronic (lasting at least 3 months of the year for two years in a row).
People with asthma may also have asthmatic bronchitis, inflammation of the lining of the bronchial tubes.
Acute bronchitis may be responsible for the hacking cough and phlegm production that sometime accompany an upper respiratory infection.
If you are otherwise in good health, the mucus membrane should return to normal after you've recovered from the initial lung infection, which usually lasts for several days.
Chronic bronchitis is a serious long-term disorder that often requires regular medical treatment.
If you are a smoker and come down with acute bronchitis, it will be much harder for you to recover. If you continue smoking, the damage to these cilia prevent them from functioning properly, thus increasing your chances of developing chronic bronchitis. There are other medications such as dasatinib (Sprycel) and nilotinib (Tasigna) that doctors may prescribe, as well. Chronic Myelocytic Leukemia, or CML is a type of cancer that begins within the bone marrow. Chronic Myelocytic Leukemia commonly affects adults from the ages of 40 to 60 years old, although it may sometimes occur in people, regardless of age or gender. As the disease progresses, increasing numbers of white blood cells appear in the bone marrow until it spreads out and enters a person’s bloodstream.
Chronic Myelocytic Leukemia affects approximately 2 in every 100,000 people, about 7 to 20% of all leukemia cases.
When a person is exposed to radiation, it could trigger the occurrence of this type of chromosome abnormality. Chronic Myelocytic Leukemia causes blood-forming cells to undergo rapid growth within the bone marrow, body tissue, and blood.
This chronic phase may last for an extended period of time, from a few months up to several years. Other symptoms of Chronic Myelocytic Leukemia include the appearance of petechiae, small red marks on the surface of the skin, and pressure felt on the left rib cage that is caused by a swelling of the spleen. Diagnosing Chronic Myelocytic Leukemia is as simple as having a complete blood count taken.
To confirm that a person is suffering from suspected CML, tests that closely examine and analyze a person’s chromosomes need to be taken to determine the existence of the Philadelphia chromosome. The doctor will conduct a physical examination to check for the presence of a swollen or enlarged spleen.
Patients suffering from Chronic Myelocytic Leukemia are usually given imatinib (Gleevec) to block the Philadelphia chromosome and to keep it from producing the abnormal enzyme, tyrosine kinase, responsible for causing the rapid production of white blood cells.

By the time CML reaches the blast crisis stage, the disease becomes very difficult to treat because of the huge number of immature white blood cells present. When combined with high-dose chemotherapy sessions, stem cell transplantation may actually eradicate CML. In a blast crisis that is not treated, the life expectancy of a person is a couple of months.
With the advent of newer drugs such as imatinib (Gleevec), patients suffering from CML have a better outlook. Every cigarette damages the tiny hair-like structures in your lungs, called cilia, that are responsible for brushing out debris, irritants, and excess mucus.
In some heavy smokers, the mucus membrane lining the airways stays inflamed and the cilia eventually stop functioning altogether. Temporarily controlling the production of white blood cells, a type of chemotherapy medicine, hudroxyurea (Hydrea) is used to impede white blood cell production during the earlier stages of CML. The soft spongy matter inside the bones known as the marrow helps in the formation of blood cells.
Two chromosomes in particular rearrange to form what is known as the Philadelphia chromosome. It is caused by an abnormality in a person’s chromosomes known as the Philadelphia chromosome, and there are many factors that bring about this type of abnormal rearrangement. Radiation exposure can be the result of a nuclear disaster, or even previous chemotherapy treatment for another cancer such as Hodgkin’s lymphoma or thyroid cancer. There are very few symptoms that manifest themselves and the disease is usually detected when people get tested during routine medical exams.
In this stage, the patient will experience a sharp drop in red blood cells and platelets, resulting in paleness, a tendency to bruise easily, and bleeding.
This test will supply the doctor with data showing an abnormally high number of white blood cells. The doctor may also order a CBC differential, aspiration of the bone marrow, genetic testing to determine the presence of the bcr-abl gene, a platelet count, and other tests to check the level of a person’s uric acid and vitamin B12. Gleevec has been recorded to be responsible for the high rates of patient remission from CML.
Patients will need to discuss all their options with their oncologist in order to decide which form of treatment will work well for them, as well as to review the various other options for treatment.
Stem cell transplantation is very difficult because the stem cells need to be harvested from a donor with the same tissue type as the patient. The symptoms of the disease abate, and the patient goes on remission for up to several years while on imatinib. In many cases, this condition is diagnosed as a result of screening when individuals are considered to be at risk of kidney problems, such as those with diabetes or high blood pressure or those related to someone with chronic kidney disease. Treatment includes painkillers, other medication and, most importantly, stopping alcohol drinking for good.
Clogged with mucus, the lungs are then vulnerable to viral and bacterial infections, which over time distort and permanently damage the lungs' airways. CML develops from cells in the bone marrow that are responsible for producing white blood cells. This rearranged pair brings about tyrosine kinase, an abnormal enzyme that in turn affects the growth patterns of white blood cells in the bone marrow.
In its blast crisis phase, leukemia cells that are produced are only the immature ones, signaling that the CML has gotten worse.
However, not all patients treated with radiation therapy for other types of cancer develop CML, and a majority of CML patients have not had exposure to radiation.

During this phase, the patient will start to experience low-grade fevers that are not caused by any infection, a swollen spleen, and bone pain.
Examined further under a microscope, these white blood cells, previously found only in the bone marrow, are less mature.
To be effective, stem cell transplantation will need to be performed during the first stage of CML.
Other medications such as busulfan (Myleran) and hudroxyurea (Hydrea) do not actually prolong a patient’s survival but are effective in relieving the symptoms of Chronic Myelocytic Leukemia.
Patients who undergo stem cell transplantation can expect long-term cure from between 60% to 80%. The condition can also be discovered when it leads to one of its notorious complications such as cardiovascular disease, pericarditis or anemia.
The Philadelphia chromosome is responsible for the abnormal number of white blood cells and platelets that are produced, and abnormal numbers of white blood cells are what lead to the occurrence of Chronic Myelocytic Leukemia. During this phase, a patient’s spleen becomes enlarged, and fever and weight loss start. However, there may be incidences of fatigue and weakness, loss in appetite and weight, as well as fever, excessive sweating at night, and a sensation of fullness. Having a transplantation procedure done when the disease is in the accelerated or blast crisis stage will not work to treat the disease at all. Your doctor can perform a breathing test, called spirometry, to see if you have developed COPD.
This drains the enzyme-rich fluid into the part of the gut just after the stomach (the duodenum). The enzymes are in an inactive form in the pancreas (otherwise they would digest the pancreas). In most cases the person has been drinking heavily for 10 years or more before symptoms first begin. They include abnormalities of the pancreas such as narrowing of the pancreatic duct (due to various reasons) and conditions inherited from one of your parents (hereditary). Undigested fat from the diet may remain in the gut and be passed with poo (faeces, stools, or motions).
Unlike a 'one-off' acute pancreatitis, the pain may then not go and ongoing chronic pain and other symptoms may then develop. Many pancreatic cells can be damaged before abnormalities show up on tests, X-rays or scans.
The amount of enzymes made by the pancreas and the number of insulin-producing cells can become quite low before any symptoms of poor digestion or diabetes develop.
This is fluid that collects in the tummy (abdominal) cavity between the organs and intestines (guts). The one chosen depends on the severity of your condition, whether the tube which leads to the pancreas (the pancreatic duct) is blocked, and also on various other factors. Examples of treatments which involve this approach are coeliac plexus block and spinal cord stimulation.

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