What does meniere tinnitus sound like zippy,what causes hammering sound in ears symptoms,my ear is ringing and feels numb symptoms,tinnitus caused by neck problems dizziness - Review

Author: admin, 26.09.2013. Category: Treatment For Tinnitus

Meniere’s disease is a chronic illness that affects a substantial number of patients every year worldwide. Fluctuating, progressive, unilateral (in one ear) or bilateral (in both ears) hearing loss, usually in lower frequencies. Nausea, vomiting, and sweating sometimes accompany vertigo, but are symptoms of vertigo, and not of Meniere's. Some sufferers also experience nystagmus, or uncontrollable rhythmical and jerky eye movements, usually in the horizontal plane, reflecting the essential role of non-visual balance in coordinating eye movements.
The American Academy of Otolaryngology-Head and Neck Surgery Committee on Hearing and Equilibrium (AAO HNS CHE) set criteria for diagnosing Meniere's, as well as defining two sub categories of Meniere's: cochlear (without vertigo) and vestibular (without deafness). The center of production for endolymph is a structure in the cochlea called the stria vascularis. Although its pathogenesis has been proposed to be a disorder of water transport in the inner ear, subsequently, it remains unsolved, until now. Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere's disease.
Meniere's disease is idiopathic, but it is believed to be related to endolymphatic hydrops or excess fluid in the inner ear. Other possible conditions that may lead to Meniere's symptoms include syphilis, Cogan's syndrome, autoimmune disease of the inner ear, dysautonomia, perilymph fistula, multiple sclerosis, acoustic neuroma, and both hypo- and hyperthyroidism. The unpredictable episodes of vertigo are usually the most debilitating problem of Meniere's disease.
This study reports on the long-term benefit of ultra-high-frequency masking with the UltraQuiet device.
This study reports on the long-term benefit of ultra-high-frequency masking with the UltraQuiet (UQ) device. Well accepted is that if maskers overlap in frequency with the tones to be masked, masking is likely to occur, its degree related to masker intensity. Because tinnitus can usually be masked (at least partially) for some period by a variety of sounds, one commonly used procedure is to assess wide-range masking, termed minimal masking levels (MMLs), using a variety of frequencies, including broad- or narrowband noise [12].
Theoretically, stimulation above the tinnitus frequency may supplement or assist the neurological reprogramming at the cortex and perhaps restore the normal-frequency spatial relationship.
The goal of this study was to evaluate the long-term efficacy of using UltraQuiet high-frequency bone-conduction therapy for treating tinnitus, using pre- and postbehavioral assessment of tinnitus loudness, tinnitus anxiety, and tinnitus severity. Fifteen subjects (3 female, 12 male) with subjective idiopathic tinnitus of the severe disabling type participated in the study.
The stimulus was produced using Kyma Version 5 software with a Capybara 320 Sound Computation Engine, and it was recorded on a compact disk (CD). The transducer is a custom-made aluminum ceramic bimorph with a high-frequency limit of some 50 kHz. The UltraQuiet stimulus parameters, or sound features, were chosen to optimize the activation of auditory cortical neurons. Classification of masking curve type according to Feldmann's system was applied to the masking data, and we measured loudness discomfort levels at 250-8,000 Hz. To assess, in a preliminary fashion, the effects of treatment length, we randomly assigned subjects to one of three groups. Before each stimulation session, subjects completed three outcome measurements: the tinnitus intensity index, the annoyance index, and the tinnitus severity index [1]. The questionnaire results for measures of tinnitus intensity and annoyance were not significantly different over the course of therapy sessions, although a drop in the mean level for each was noted on the last few trials. We examined the relationship among high-frequency MMLs, tinnitus pitch, tinnitus intensity, and Feldmann masking curves. The use of high-frequency bone conduction stimulation using the UltraQuiet therapy system resulted in longterm reduction in tinnitus severity during therapy, and that tinnitus relief lasted for at least 2 months after therapy in most subjects in this study. During posttherapy interviewing, we noted partial masking of the tinnitus by the UltraQuiet system throughout the trial in all patients (although not in every session). Frequency range of stimulation is critical in the auditory cortical reprogramming approach of the UltraQuiet system; however, any reduction in the amount of masking required to eliminate (or partially eliminate) tinnitus also is important. Alternatively, we could argue that the energy around 6 kHz was predominant in our subjects owing to mild to moderate sensorineural hearing loss.
RI, which refers to a decrease in the perceived intensity of the tinnitus for a time after the masking stops, was first reported by Feldmann [12].
Because the UltraQuiet stimulus generally overlaps with high-frequency tinnitus and the presentation is just above threshold stimulation (~6 dB SL), inhibition should be facilitated. Treating tinnitus patients with the UltraQuiet device is more difficult when their tinnitus is of the severe problematic type. Problematic tinnitus is most likely related to changes in the auditory pathway and consequent reactions in various areas of the brain.
The authors acknowledge the support of Sound Technique Systems, LLC, in this study and the assistance of Robert Guinta. Tinnitus Self-help - What should you do when it whistles, rings, roars or drones in your ear? The most important and encouraging information is the fact that tinnitus has a benign cause in 99% of all cases. Would knowing that oxymetazoline spray is the generic form of the off the shelf Dristan nasal spray? The disease is characterised by intermittent episodes of vertigo lasting from minutes to hours, with fluctuating sensorineural hearing loss, tinnitus, and aural pressure. It is diagnosed based on the presence of a cluster of symptoms which may not occur in unison, making it less likely for a physician to make the diagnosis. However, a detailed otolaryngological examination, audiometry and head MRI scan should be performed to exclude a tumour of the eighth cranial nerve or superior canal dehiscence which would cause similar symptoms. Once the endolymph is created it is distributed throughout the scala media of the cochlea, and is then absorbed into the endolymphatic duct and sac. A recent study revealed that both plasma stress hormone, vasopressin (pAVP) and its receptor, V2 (V2R) expression in the inner ear endolymphatic sac were significantly higher in Meniere's patients. The episodes often force a person to lie down for several hours and lose time from work or leisure activities, and they can cause emotional stress. One study found that 15 of 47 patients with Meniere’s disease who had failed to respond to previous treatments improved with B6 (pyridoxine). In addition, on bad days, using a B-complex several times a day instead of only once can help also.
A commercial product, UltraQuiet provides a new form of high-frequency bone conduction therapy. In the case of masking tinnitus by an external noise, this relationship is more the exception than the rule.
The masking stimulus is raised in 5-dB steps, and patients are asked whether their tinnitus is still audible. The stimulation must be very high in spectral content to accomplish this above the tinnitus pitch requirement. Music appears be a more effective tinnitus masker than is noise [19], possibly owing to the involvement of more central and cognitive processes. The CD recording stimulus consisted of digitally processed music (44.1-kHz sampling rate) with playback in the 10- to 20-kHz range. Spectrum of the high-frequency bone-conducted stimulation ranges from approximately 6 kHz to 20 kHz. The transducer is coupled to the skin and held in place with a band, much as are traditional clinical boneconduction transducers. Cortical neurons have been shown to be sensitive to frequency edges, temporal patterns, and frequency or intensity transitions [20].
We presented outcome questionnaires to establish a baseline of functioning; these included the tinnitus intensity index, the annoyance index, and the tinnitus severity index [1,21,22]. No one indicated a poorer result, and those four reporting no change in their tinnitus did indicate improvement on measures of tinnitus intensity or severity after therapy treatment. That is, as a group, the patients with problematic tinnitus indicated a significant reduction in severity over the course of the treatment trials.
Effects of high-frequency therapy on three outcome measures - tinnitus severity, intensity, and annoyance - as evaluated by questionnaires completed after each therapy session. For some patients at some frequencies, reductions in MMLs were as high as 25-45 dB in one ear (Fig. Decrease in the minimum masking levels (MMLs) for the six patients who received brain imaging before and after therapy.
Mean minimum masking levels for all subjects when patient and ear data are collapsed reveals a frequency-specific pattern.
Individual variability in this small sample of patients with problematic tinnitus precluded any detailed analysis, but tinnitus intensity ratings exceeding 50 dB were associated with improvement on the overall tinnitus relief questionnaire and were associated with a high-frequency pitch match. Relationship among minimal masking level changes (by frequency), Feldmann masking curve (FMC) types, and pitch and loudness matches in all subjects.
Hearing thresholds before and after therapy generally suggest improvement after therapy; however, the pattern was complex and included elevation in some frequencies.


Threshold was established before each session but, given the problems in detecting a stimulus in the presence of tinnitus (even in skilled hands), the level of UltraQuiet therapy may have been as little as 2-3 dB SL for some patients in some sessions. Patients in the 10-session group averaged just above "no change," whereas those in the 12- and 14- session groups averaged above "slight improvement." What must be emphasized is that these patients with problematic tinnitus have had limited therapeutic success with other treatment modalities. The tinnitus relief was inferred from a pattern of lower weekly scores on the tinnitus severity scale and reduction in MMLs. Owing to stringent adherence to the protocol approved by the Western Institutional Review Board, we made no effort to increase the stimulation level in an attempt to produce complete masking.
All patients had serviceable hearing to 12 kHz, but hearing improvement may have been related to relative frequency sensitivity of the UltraQuiet stimulus. In an individual with hearing loss and tinnitus, RI may last for a few seconds or minutes but can last days or weeks [2,31]. The acceptance of RI over questionnaire data is understandable in an effort to obtain a more "physiological" metric. What effect the increase in stimulation level from 6 dB SL to 12 dB SL would have on the effect of masking, on further reduction in MMLs, and on increased RI remains to be explored.
When contrasted to normal controls and tinnitus patients who tolerate their tinnitus, patients with problematic tinnitus showed less habituation in middle latency potentials [36].
The emerging picture is that of an initial insult to the ear or brain (or both) followed by an increase in the tinnitus frequency cortical map, which could increase dyssynchrony-synchrony and loudness and reduce habituation.
Department of Otolaryngology, State University of New York, Downstate Medical Center, Brooklyn, and Martha Entenmann Tinnitus Research Center, Forest Hills, New York. In collaboration with affected persons and with specialists we are researching and developing new forms of therapy and evaluating their chances of success. In Step 2 you will receive an overview of the most appropriate of the therapy possibilities. Although there is currently no cure, more than 85% of patients with Meniere’s disease are helped by either changes in lifestyle and medical treatment, or minimally invasive surgical procedures such as intratympanic steroid therapy, intratympanic gentamicin therapy, and endolymphatic sac surgery. Meniere’s disease appears to predominantly affect adults around the age of 40 years, with a range of onset between 20-60 years.
There is no definitive test for Meniere's, it is only diagnosed when all other causes have been ruled out. The endolymphatic sac of Meniere’s patients can malfunction, thus not allowing the endolymph to be reabsorbed. Three patients failed to improve and others gradually improved but it was uncertain whether pyridoxine supplementation was responsible. To assess its effectiveness in tinnitus treatment, we selected 15 patients with problematic tinnitus and randomly assigned them to three variations of the medical-audiological tinnitus patient protocol modified for the UltraQuiet study. Logically, high-frequency masking should provide effective relief in persons with severe problematic tinnitus.
The UltraQuiet device delivers amplitude-modulated musical-type stimulation in the range of 10-20 kHz suitable for this purpose. We specifically investigated the use of the UltraQuiet device for providing relief, masking, and RI in individuals with problematic tinnitus of the severe disabling type. The stimulus consisted of synthesized music digitally processed and used to modulate a carrier at 16 kHz. The CD was played through a custom-made amplifier into a piezoelectric bone-conduction transducer. Some energy occurs around 6 kHz, owing to the transducer's fundamental resonance and the high-pass filter slope.
In other words, features that are found in speech, music, or amplitudefrequency modulation were incorporated into the stimulus to facilitate auditory cortical activation. Audiological evaluation included pure-tone audiometry, speech audiometry, tinnitus pitch and loudness matching, the measurement of RI, and masking curves to establish MMLs at 250-8,000 Hz using both narrowband and white noise.
One week after the last intervention session, we repeated the audiological evaluation and administered the outcome questionnaires to assess any changes.
Group 1 received stimulation twice weekly for 2 weeks, stopped the stimulation for 2 weeks, then received stimulation twice weekly for 3 weeks, for a total of 10 sessions.
The stimulation lasted 30 minutes for the first session and 1 hour for all succeeding sessions. Some patients indicated more improvement than others, but the trend in all patients was an increase in tinnitus relief.
Note the general improvement that lasted for 2 months in approximately one-half of the patients.
Tinnitus severity improvement for the group was evident at the second session, gradually increasing through the twelfth session.
Clearly the severity is decreasing, with a trend in that direction for anxiety and loudness.
The tinnitus pitch match most frequently occurred in the region of the hearing loss but not necessarily at the frequency with the maximal loss. Dynamic hearing levels appear related to central processes assumed to be active during and after therapy.
Note in Figure 3 that dramatic improvement in tinnitus severity occurs in session 12, as does a modest abatement of tinnitus intensity and annoyance. Four factors likely contributed to long-term tinnitus relief: ultra-high-frequency masking, RI, neurological reprogramming, and habituation. The strategy of using high frequencies at low levels was designed to potentially provide some partial masking but, more important, was designed to aid in tinnitus neurological reprogramming and habituation. This is suggested by the six cohort patients in whom positron emission tomography scans were obtained.
High-frequency stimulation, both in the high audiofrequencies (UltraQuiet) [2] and in ultrasonic frequencies [11], have resulted in RI. We observed (by interview at the end of therapy but not by formal testing) RI lasting approximately 5 minutes. The conclusion of Shulman [15] suggests that a brain-imaging index in conjunction with high-frequency audiometry may be the technique of choice in objectively assessing tinnitus relief from auditory therapy if neurological reprogramming and habituation are the essential processes as hypothesized.
Cortical reprogramming as a consequence of sensorineural hearing loss has been well established [33, 34]. In view of the degree of improvement and results with the limited number of sessions in our study, a reasonable expectation is improved results with an increased level of stimulation (12 dB SL) and an increased number of sessions over time. Additionally, auditory brainstem response differences between tinnitus patients and controls further suggest that auditory path- way transmission may influence abnormal habituation. Such a condition could hyperactivate the medial temporal and prefrontal lobes, resulting in problematic tinnitus characterized by annoyance, and could trigger autonomic reactions. Ultra-highfrequency acoustic stimulation and tinnitus control: A positron emission tomography study. Functional inactivation of the amygdale before but not after auditory fear conditioning prevents memory formation.
Local improvement in auditory frequency discrimination is associated with hearing-loss slope in subjects with cochlear damage.
Loudness perception and frequency discrimination in subjects with steeply sloping hearing loss: Possible correlates of neural plasticity.
Test-retest reliability of pure-tone thresholds from 0.5 to 16 kHz using Sennheiser HDA 200 and Etymotic Research ER-2 earphones.
High-frequency (8 to 16 kHz) reference thresholds and intrasubject threshold variability relative to ototoxicity criteria using a Sennheiser HDA 200 earphone. Environmental enrichment improves response strength, threshold, selectivity, and latency of auditory cortex neurons. Abnormal auditory mismatch response in tinnitus sufferers with high frequency hearing loss is associated with subjective distress level.
In order to be certain about even the last percent, one should go to an ear, nose and throat specialist. Vestibular neurectomy has a very high rate of vertigo control and is available for patients with good hearing who have failed all other treatments. The disorder does affect a small number of children younger than 20 years, and these cases comprise around 3% of all Meniere’s cases.
An endolymphatic sac blockage can cause the endolymph volume to increase along with the pressure within the cochlea.
Furthermore, 23 patients with vertigo due to unknown causes received pyridoxine and many of them responded. We assessed tinnitus relief by questionnaires directed at weighing patient response to overall effectiveness, tinnitus loudness, tinnitus severity, and tinnitus annoyance. The effect of this expansion on connections to the limbic system and other cortical areas is not known, nor have the tuning characteristics of these "recruited" neurons been measured. Preliminary clinical reports were encouraging [2] and a calibration procedure, anchored to international standards, was followed [18].
The pitch match to the tinnitus for 14 of the 15 subjects was high-pitched, matching to either a pure-tone or a narrowband noise or a combination of both, with frequencies between 3 and 16 kHz; 1 subject had a low-pitched tonal tinnitus at 450 Hz.
Group 2 received stimulation twice weekly for 3 weeks, stopped the stimulation for 2 weeks, then received stimulation twice weekly for 3 weeks, for a total of 12 sessions.


Further improvement may be present but is obscured by the duration parameters of the three groups. The mean data are perhaps as revealing; when patient and ear data are collapsed, a high-frequency reduction in masking is observed (Fig. Although we saw an increase in some thresholds in some patients, twice as many thresholds improved as those that decreased. Nonetheless, the frequency range of masking is important in obtaining neurological reprogramming and inhibition [16,18].
Those patients with the best thresholds beyond 10 kHz exhibited the best behavioral and physiological activity [15]. The question of the minimal number of trials needed to note tinnitus relief, given that choices were limited to 10, 12, and 14 sessions, can be answered only by stating that 10 session of therapy (and probably fewer) are not as effective as 12 and 14 sessions, on the basis of questionnaire results after therapy. Patients with problematic tinnitus appear not to exhibit normal habituation, and this can influence their perception of tinnitus loudness.
Although we readily recognize that the neural substrate of problematic tinnitus encompasses much more than the auditory pathway, the role of the auditory pathway in masking, RI, neurological reprogramming, and habituation is significant [37]. In GE Reich, JA Vernon (eds), Proceedings of the Fifth International Tinnitus Seminar 1995. Poster presented at the Twenty-First Annual Meeting of the Association for Research in Otolaryngology, 1999. Presented at the Thirty-First Congress of the Neurootological and Equilibriometric Society, Bad Kissingen, Germany, March 25-27,2004.
If the diagnosis is benign then, medication or surgical treaments will have scarcely any effect here. Labyrinthectomy is undertaken as a last resort and is best reserved for patients with unilateral disease and deafness.
Additionally, we performed audiological measures (including pure-tone and speech audiometry, minimal masking levels, pitch and loudness matching, and residual inhibition).
That is, tinnitus masking may be a complicated product of peripheral and central processes, and sounds outside of traditional psychoacoustic ranges can be effective with tinnitus [2], including ultrasound masking delivered through bone conduction [11]. If neural space expansion of the tinnitus frequency (or frequencies) is associated with synchronized activity, ignoring an attentiongenerating tinnitus percept that could readily arise may be impossible.
The UltraQuiet system has a maximum output of 53 dB hearing level (HL) when it is massloaded to the artificial mastoid with 5.4 Newtons of force applied. Group 3 received stimulation twice weekly for 4 weeks, stopped the stimulation for 1 week, then received stimulation twice weekly for 3 weeks, for a total of 14 sessions. The threshold for stimulation was established, and the stimulation was presented 6 dB above threshold or 6-dB sensation level (SL). That is, for the latter sessions, the number of patients being tested dropped, owing to the session limitations for each of the three treatment groups. No consistent pattern was noted between Feldmann masking curve type and tinnitus pitch match (Fig.
If highfrequency stimulation is essential for auditory cortical reprogramming, the sensitivity to such stimulation should be an essential variable.
What should be noted is that the stimulating intensity was only 6 dB SL, and this may not have been sufficient energy to elicit RI in the other patients, a metric to be systematically studied in the future. If the auditory cortex has reprogrammed, stimulation with very high frequencies might stabilize and reverse the process and perhaps restore the normal frequency map.
According to these serial measures, therapy of fewer than 12 sessions would not be as satisfactory as therapy lasting 12 and 14 sessions.
A plastic auditory pathway treated with a stimulus specifically designed for highpitched tinnitus may, with time, provide long-term relief. The natural biochemical mechanism for relieving this endolymphatic sac blockage is to release hormones which cause an increase in endolymph, creating even more hydraulic pressure in the cochlea. All patients showed some long-term gains, and most exhibited relief in at least one measurement parameter, providing support for the use of high-frequency vibration in the treatment of tinnitus. Growing evidence suggests that high-frequency masking is desirable in cases of high-frequency tinnitus [2,11]. Increased degrees of neural synchronydyssynchrony could activate and continue to stimulate the amygdala, an organ known to be critical in evoking emotional and autonomic nervous responses [17].
Although the stimulus is presented on only one side of the head, it is heard binaurally through bone conduction [23].
The frequency area that exhibited the greatest effect is the octave from 3 to 6 kHz, below the lowest resonance in our transducer (6 kHz). Annoyance and tinnitus intensity seemed to persist in most throughout the sessions, suggesting that the tinnitus, while reduced in severity, was still present. In the normal auditory system, an increase in loudness is related to an increase in neural activity. The changes in MMLs and auditory thresholds suggest an adaptive central nervous system, responsive to high-frequency sound therapy.
We will try to advise you objectively and to inform you about the most promising of the treatment possibilities. Morrison found an autosomal dominant inheritance pattern with 61% penetrance for 41 families.
Eventually there is a release of this endolymphatic sac blockage, allowing the pressure of the cochlea as well as the endolymph volume to return to baseline. Two problems exist: One is developing an efficient, commercially viable, and calibratable transducer and the other is determining a reliable clinical-use protocol.
For many patients, substituting one sound for another is not considered a significant enough improvement; additional relief is desired.
Stated another way, the frequencies that required less energy to mask tinnitus were those just below the lowest effective stimulating frequencies in the UltraQuiet system. The UltraQuiet masking mechanism appears to be different when using conventional audiological masking at 250-8,000 Hz than when using ultra-high frequencies. High-frequency stimulation with the UltraQuiet passband of 10-20 kHz has the added quality of disrupting the tinnitus frequency synchrony and reducing the overrepresentation, which might be verified with cortical potentials.
Patients who do not exhibit normal habituation and who rate their tinnitus as loud may have more active dyssynchronous neurons involved in tinnitus perception than do patients who assess their tinnitus loudness as low. Long-term tinnitus relief cannot be solely defined by one metric as complete masking or RI on the order of hours. This pressure release is responsible for the vertigo symptoms that occur during a full-blown Meniere’s attack. In a preliminary report [2], we found a high-frequency tinnitus device, UltraQuiet, to be efficacious. The masking stimulation, if properly chosen, may have the capacity of changing how the brain processes tinnitus, which could provide long-lasting benefit.
These frequencies were on the edge of the patients' audiometric hearing loss, a region often associated with increased discrimination possibly due to neural plasticity [24,25].
With ultra-high frequency, the stimulus is apparently combined with neurological reprogramming and plasticity involving the auditory cortex. Such a situation would be predicted in the tinnitus frequency map expansion in the auditory cortex and would influence both the medial temporal lobe system and other cortical area identified as active in tinnitus [37]. Relief is a complex function of many factors arising both within and outside the auditory system, and successful treatment takes time. The MML improvement was related to the measured tinnitus pitch in that both were high-frequency (with one pitch match exception). RI increased with masker intensity, but the relationship of RI to tinnitus frequency, masker center frequency, and bandwidth was complex and varied among individuals. Brain imaging and high-frequency audiometries seem to be important indices in quantifying tinnitus relief. Often, behavioral measures are contradictory, rendering efficacy determination problematic. These include ear infections, foreign bodies or wax in the ear, injury to the ear caused by loud noises or a diseased condition called Menierea€™s disease.
When heard from both ears the sound is described to come from the a€?middle or the heada€?.
This is done to assess the disease process in the brain An MRI scan of the brain also shows in detail the disease process, tumor or aneurysm that may be causing the tinnitus An angiography is a blood vessel study that looks for aneurysms or blood vessel abnormalities. This is a computerized test that looks at the nerve pathways that connects the brain with the ear.
Some hearing aids and devices help patients with tinnitus with making a constant humming noise in the background called white noise. Relaxation techniques and avoidance of drugs that cause tinnitus like aspirin, loop diuretics etc.



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