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21.12.2015
A study in mice shows that a compound in traditional Chinese medicine could help weight loss by activating brown fat. Obesity is reaching epidemic proportions worldwide, leading to a rise in associated diseases such as Type 2 diabetes and cardiovascular diseases. When obese mice were given berberine supplements, they were protected from weight gain, had reduced free fatty acids and showed improved glucose tolerance. The authors found that berberine treatment activated brown adipose tissue, the type of fat that burns lipids to produce heat. Although the results suggest that berberine-induced activation of brown adipose tissue is a promising way of treating obesity, Prof.
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When our metabolism slows down, the body will store fat rather then burn calories, causing an accumulation of fat.


27, 2014) - A compound isolated from a Chinese medicinal plant could help fight obesity by increasing the conversion of fat to heat. Obesity develops when energy intake exceeds energy expenditure; approaches to managing obesity therefore either focus on reducing energy intake through dietary restrictions, or increasing energy expenditure through exercise.
Recent studies have revealed that adult humans also have functional brown adipose tissue, a finding that has fueled speculation that the pharmacologic enhancement of brown adipose tissue might be a useful strategy and a hopeful target for counteracting obesity," Shanghai Jiatong University's Professor Guang Ning told Asian Scientist Magazine.
Ning and his team have found that berberine supplements could be an alternative method of increasing energy expenditure. Berberine-treated mice also had higher body temperatures, better cold tolerance and increased energy expenditure, as determined by a comprehensive lab animal monitoring system (CLAMS). Furthermore, berberine treatment induced the conversion of white adipose tissue to brown adipose tissue, increasing the expression of the brown adipose tissue marker UCP1 at both the mRNA and protein levels.
When mice were treated at 30°C rather than 22°C, they had significantly less weight reduction. However, in order to study the direct effects of berberine rather than its effect via modulation of intestinal bacteria, we gave the mice berberine via an intraperitoneal injection.


A plant alkaloid present in many traditional Chinese herbs, berberine is commonly used to treat diarrhea but has recently also been shown to improve metabolic conditions such has insulin resistance.
This mode of administration is not possible with human subjects, so it remains to be seen whether berberine will have the same effects on brown adipose tissue when administered orally," he said. More importantly, your metabolic rate is low, which means that you don't burn calories you consume every day and in time it causes an accumulation of fat.
To burn fat cells stored in body tissues effectively, Lishou Capsules uses the mechanism of increasing you metabolic rate.



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