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For best absorption, Calcium pills should be taken with food, and doses should not exceed 500 mg at a time.
Pernicious anemia is a type of megaloblastic anemia that occurs with severe vitamin B12 deficiency. There are several types of anemia, and they are usually classified by the way they impair red blood cells in size and shape. With megaloblastic anemia, your body starts producing red blood cells that are overlarge, misshapen, and poorly developed.
Your body starts receiving less oxygen, causing a breakdown in various bodily functions of the organs, tissues, and nervous system. Pernicious anemia is a type of megaloblastic anemia caused by vitamin B12 malabsorption, the inability to digest vitamin B12 found in meat, fish, dairy, and egg products.
Pernicious anemia used to be fatal, until scientists discovered that symptoms could be cured with vitamin B12 supplementation. Even if you eat plenty of beef, chicken, and fish, you may still have vitamin B12 deficiency through lack of intrinsic factor, an enzyme needed to digest and absorb vitamin B12. Pernicious anemia is one type of megaloblastic anemia; another type occurs with folic acid deficiency.
If you found this article helpful, then please share with your friends, family, and coworkers by email, twitter, or Facebook. Tags: intrinsic factor, Large red blood cells, Megaloblastic, Megaloblastic anemia, oxygen and vitamin B12, pernicious anemia, red blood cells, Vitamin B12, vitamin B12 deficiency, vitamin B12 food sources, Vitamin B12 malabsorption Posted in Pernicious Anemia- What is it? Are constant eyelid twitching and eye spasms driving you batty?  Myokymia might be a sign of pernicious anemia caused by low vitamin B12 levels.  Learn how to stop eye twitching by halting vitamin B12 deficiency in its tracks. It can also occur on your face- hemifacial spasms are muscular twitches that begin on one side of your face, usually the eye.  Over time, hemifacial spasms can expand to include the rest of your face, on one side.
Myokymia is a type of nerve damage called trigeminal neuralgia.  When your eyelid keeps twitching out of control, it is because the nerves that control the opening and closing of your eyes have been damaged. Causes of eye twitching may include stress, excessive alcohol usage, and staring at a computer screen for long periods of time.  Eye spasms can also be a reaction to caffeine, or may signify low levels of cobalamin- vitamin B12.
Vitamin B12 benefits include red blood cell production, protection of the nervous system’s myelin sheathe, cognitive functioning, DNA synthesis, and lowered homocysteine levels. If your body does not store adequate amounts of vitamin B12, you may get B12 deficiency, and ultimately severe pernicious anemia, a type of megaloblastic anemia blood disease.
Pernicious anemia symptoms include severe nerve damage, such as eyelid spasms caused by myokymia.  Lower eyelid twitches are most common with vitamin B12 deficiency patients. If you suspect that you have vitamin B12 deficiency, then consult your physician and request a blood test for B12 levels.
Vitiligo is a skin disease that often occurs with vitamin B12 deficiency- Find out if taking B12 supplements can treat your vitiligo symptoms and get rid of white patches on your skin forever. Doctors are uncertain what exactly causes the skin disorder vitiligo, but they believe it might be an autoimmune disorder. Vitiligo causes telltale patches of white skin (depigmentation), typically on parts of your body that get the most sun exposure, like your hands, feet, and face, particularly around the eyes, mouth, and lips. Other symptoms of vitiligo may include premature hair greying, including grey eyelash hair.  White patches can also occur in the inside of the mouth. For some, vitiligo symptoms remain only in one area of the body.  For others, patches of white skin may slowly spread over years to other parts of the body.
In one clinical study, vitamin B12 and folic acid were administered to patients who suffered from vitiligo.  They were also instructed to keep records of sun exposure.
More than half of the 100 vitiligo patients noticed dramatic results- 37 of which had opted for sun exposure. Six volunteers who took the vitamin B12 and folic acid supplements experienced noticeably superior results. Scientists confirmed that supplementing with vitamin B12 and folic acid, combined with sun exposure, is more beneficial for vitiligo patients than simple sun exposure alone.

What is pernicious anemia, and how is it different from vitamin B12 deficiency or megaloblastic anemia?
Pernicious anemia, a form of megaloblastic anemia, is a disease that impairs red blood cell distribution through vitamin B12 deficiency; for that reason, it is also called vitamin B12 malabsorption anemia. Other names for pernicious anemia are Biermer’s anemia, Addison’s anemia, and combined systems disease (a disorder of the nervous system). Whenever you eat foods that contain vitamin B12- protein foods like beef, chicken, seafood, cheese, and eggs- your digestive system produces a chemical called intrinsic factor, a digestive enzyme.
Intrinsic factor then grabs the vitamin B12 from your stomach, bonds to it, carries it through the small intestine, and delivers it to the ileum, at the base of your small intestine. People who suffer from pernicious anemia are not able to manufacture or regulate the intrinsic factor enzyme.  Even if they eat plenty of foods rich in vitamin B12, they are unable to digest the essential vitamin, and the result is a catastrophic depletion of vitamin B12 levels in the blood. Untreated, vitamin B12 deficiency causes low red blood cell production, forgetfulness, severe nerve damage, and increased risk for heart attack , stroke, and osteoporosis.
Since pernicious anemia results from vitamin B12 deficiency, the only remedy you need is…more B12!
If it is determined that you lack intrinsic factor, then you will need to take vitamin B12 supplements, most likely for the rest of your life, in order to avoid getting vitamin B12 deficiency again. Assuming you are getting the correct dose of vitamin B12, and are taking an efficient method of B12 supplements…most patients start to feel notably better within 24 hours of vitamin B12 supplementation. Family history is one of many causes of pernicious anemia.  If your family has a history of suffering from pernicious anemia, then you should take routine blood tests for vitamin B12 deficiency throughout your life. Scientists have noted a high correlation between pernicious anemia and many other autoimmune disorders. Pernicious anemia can happen to somebody of any age group.  Because your body stores vitamin B12 in the liver for several years, you may not know that your body has stopped absorbing it until you start to feel the symptoms, by which time your B12 levels will have dropped severely.
Gastritis- painful inflammation of the stomach lining- has many possible causes.  The most common are alcohol abuse, chronic vomiting, and overusing drugs such as aspirin.
Pernicious anemia may cause gastric polyps, increasing one’s risk for getting stomach damage or gastric carcinoid tumors. Tags: Autoimmune Disorders, b12, B12 shots, intrinsic factor, Megaloblastic anemia, pernicious anemia, Pernicious anemia stomach cancer, Pernicious anemia symptoms, symptoms of vitamin b12 deficiency, vitamin B12 deficiency, vitamin B12 malabsorption anemia, Vitamin B12 pills, vitamin b12 supplements, What is pernicious anemia Posted in Pernicious Anemia- What is it?
If you have vitamin B12 deficiency, then it is important to recognize the symptoms of pernicious anemia, as low levels of B12 (cobalamin) may be caused by this form of megaloblastic anemia, a potentially life-threatening disease.
With pernicious anemia, your body is unable to digest vitamin B12 from food sources, due to a lack of the intrinsic factor digestive enzyme.
Since vitamin B12 is crucial for all sorts of biochemical reactions, such as protecting your nerve cells through myelin production, converting fat into energy, and supporting red blood cell production, the results of pernicious anemia can be debilitating. The best way to avoid getting vitamin B12 deficiency is to include animal-based protein foods in your diet, particularly beef liver, clams, oysters, poultry, eggs, milk, and yogurt. Still, eating meat and dairy products does not guarantee you will not become deficient in vitamin B12, as there are many risk factors that can inhibit proper absorption of this vitamin.
Patients of pernicious anemia need to get routine doses of vitamin B12 supplements, usually in the form of vitamin B12 shots.  The amount and frequency of B12 injections depend on the severity of the pernicious anemia symptoms. For extra doses of vitamin B12 between doctor visits, B12-anemia patients have the option of supplementing with over-the-counter (OTC) vitamin B12, as well. Reproduction in whole or in part in any form or medium without express written permission is prohibited. Obesity is considered the single best predictor for whether someone will develop type 2 diabetes. When fat is constantly being stored, instead of mobilized, a vitamin D deficiency could result. Researchers classified study participants by their body-mass index (BMI) as well as whether they had diabetes, prediabetes (fasting blood glucose level between 100 and 125), or no glucose metabolism disorder. The researchers wrote that vitamin D deficiency and obesity appear to interact synergistically to heighten the risk of diabetes.

Most vitamin D supplements sold in supermarkets and drug stores is in the form of vitamin D3. You can increase your vitamin D absorption from food if your vitamin D food is eaten with fat.
Effect of vitamin E supplementation on vitamin K status in adults with normal coagulation status -- Booth et al. To find the right treatment and understand symptoms of fatigue, depression, and chronic pain, it helps to understand how pernicious anemia impairs your red blood cells and what you can do for prevention. Specifically, megaloblastic anemia is a blood disorder in which red blood cells called megaloblasts become too large to function properly, resulting in fewer healthy red blood cells needed to deliver oxygen throughout your body; symptoms of memory loss, extreme fatigue, dizziness, and agitation occur when your vital organs and tissues don’t receive enough oxygen. Since vitamin B12 is crucial for healthy red blood cell production, long-term vitamin B12 deficiency can progress into severe pernicious anemia, a once-fatal condition that is now prevented through vitamin B12 supplementation. If so, what kind of vitamin B12 supplements do you use- vitamin B12 shots or over-the-counter vitamin B12?
Once you start taking vitamin B12, you will notice a decrease in pernicious anemia symptoms immediately, and total reversal of symptoms by the time your B12 levels return to normal. That is one of many questions that people have about pernicious anemia- questions that are answered here. If I have one autoimmune disease like pernicious anemia, am I more likely to have another autoimmune disease? Because one of the side effects involves grossly misshapen and enlarged red blood cells, pernicious anemia has been classified as a type of megaloblastic anemia. Several studies have suggested that low vitamin D intake is also a major risk factor for development of both type 1 and type 2 diabetes. They found that vitamin D levels were directly correlated with glucose levels, but not with BMI.
They suggested that healthy people may be able to reduce their risk of developing diabetes with a healthy diet and outdoor activity. This blog is dedicated to providing up to date research, news and resources pertaining to vitamin B12, general health information surrounding the benefits of vitamin B12.
Only your doctor can answer that by taking blood tests, determining if your body makes intrinsic factor, and prescribing the proper venue of vitamin B12 supplementation.
New research has found that people who have low levels of vitamin D are more likely to have diabetes, regardless of how much they weigh. Obese subjects who had not developed prediabetes or diabetes had higher levels of vitamin D than diabetic subjects.
Focus on healthy “essential” fats contained in foods such as nuts, avocados, salmon and olive oil. Learn from, and contribute to information on B12, vitamin B12 and other connected subjects. Adipose tissue is constantly turning over in people of normal weight, as the body mobilizes and metabolizes fat during rest and in the “fasting state.” This is usually during the 12 hours between dinner and breakfast separated by sleep.
What’s more, lean diabetics or prediabetics were more likely to have low levels of vitamin D. Most people can easily absorb vitamin D and it doesn’t matter when you take it or if you take it with meals. Cooking with oils made with canola, sunflower or flaxseed oil also provide the essential fats you need to facilitate the absorption of a vitamin D supplement in your digestive system.

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