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03.11.2014
What follows is that Qsymia is specifically efficient in case your obesity is an effect of how often and how much you eat.
Given that phentermine is similar to amphetamine, it might also create similar problems, especially when it is used for a longer time. Other possible side effects of Qsymia include mood changes, sleeping problems, memory and concentration disorders.
To avoid the aforementioned problems, you should drink plenty of liquids while taking Qsymia. This is why Belviq should not be taken by people with psychotic or thought disorders and, believe it or not, also by men with deformed penis or with an unusually long lasting erection. Subscribe to our social channels so you can keep up with all fresh news and tips from this weight loss blog.
The drug formerly known as Qnexa (now ita€™s Qsymia) has been approved by the Food and Drug Administration for weight loss.
After the most obvious question about Qsymia (ita€™s pronounced kyoo-sim-EE-uh), the second most obvious question is whether the drug works. Critics have noted that the stimulant in Qsymia was also a component in Fen-Phen, a diet drug craze in the 1990s that ultimately was discontinued after evidence linking it to heart valve problems. Apovian: I began off label as soon as I heard about Phase III [randomized, controlled multi-location] trial results a few years ago.
Ita€™s the second approval of an anti-obesity agent in 10 years and the best weight-loss agent. Topiramate, one of Qsymiaa€™s components, is teratogenic [can interfere with fetal development], and another component, phentermine, can increase heart rate and blood pressure. What about critics who say weight-loss drugs generally don’t work well and can be dangerous, as in the case of Fen-Phen? We have evidence that a ten percent weight loss improves mortality and co-morbidities for obese patients, and doctors will evaluate the risk-versus-benefit of Qsymia, just like they do with any drug for other conditions.
I wonder if drugs like this can become a crutch, an excuse for patients to ignore diet and exercise as part of their weight-loss plan? Thata€™s the same as saying that drugs for type 2 diabetes are a crutcha€”just stop eating sugar and carbohydrates.
I think it will be used as an adjunct to diet and exercise and behavior modification as a first-line medication, if the patient has no contraindications to using the drug, such as childbearing potential and inability to take contraceptives or uncontrolled blood pressure or heart disease. Obesity is a disease, and we are seeing that the paradigm for obesity treatment is shifting.
Females of reproductive potential should have a negative pregnancy test before treatment and monthly thereafter and use effective contraception consistently during Qsymia therapy. Qsymia may affect how you think and is associated with difficulty with attention and concentration, memory and word-finding.
Of course, obesity itself is not without risk and, according to new numbers out today, America needs to do something fasts. But for those who have chronically struggled to even begin a path toward a healthier weight, it may be, when combined with smart food choices, education, and exercise, just what the doctor ordered.
Topiramate aka Topamax is well known to cause mental slowing (while you’re on it), so depending upon your hair color, now you really can be skinny, blonde and stupid. From what I’ve heard from Qsymia pharma reps (I am a medical device rep), a lot of doctors have been prescribing these two drugs, in generic form, separately. Prescription weight-loss drugs are generally prescribed to patients haven’t been able to lose weight through diet and exercise, and who have health problems because of their weight.
Before selecting a medication for you, your doctor will consider your health history, possible side effects and potential interaction of weight-loss drugs with other medications you’re taking.
Qsymia contains a combination of phentermine and topiramate in an extended-release capsule. Before you take Qsymia, tell your doctor if you have high blood pressure, heart disease, diabetes, liver or kidney disease, low blood levels of potassium, or if you have had a heart attack or stroke in the past 6 months. Phentermine may be habit-forming and should be used only by the person for whom it was prescribed. The phentermine portion of Qsymia reduces appetite while the topiramate portion of Qsymia helps stop cravings for hunger.A  Both of these drugs have been on the market for a long time but combined for the first time in Qsymia. The combination of craving reduction and hunger suppression has been FDA approved to help people lose weight. Belviq works on serotonin receptors in the brain, changing the neurotransmitter action of serotonin, the brain chemical that affects mood. The safety and effectiveness of BELVIQ in combination with prescription, over-the-counter, or herbal weight loss products is not known. It is not known if BELVIQ changes your risk of heart problems or of stroke, or death due to heart problems or stroke.
Phentermine is the most commonly prescribed prescription appetite suppressant in the world, accounting for 50% of the prescriptions.


Phentermine first received approval from the Food and Drug Administration (FDA) in 1959 as an appetite suppressant for the short-term treatment of obesity.
Since phentermine has been on the market such a long time, no new efficacy trials have been conducted. Before a doctor will prescribe a prescription weight loss drug, he or she will ask you about the following: any existing allergies you may have, whether or not you are pregnant or breastfeeding, and what types of other drugs you may be taking. En poursuivant votre navigation sur ce site, vous acceptez l’utilisation de Cookies, utilises pour des besoins de statistiques et d'affichage. Restez connectes a toute l’actualite sante du monde en vous inscrivant a notre newsletter ! The Food and Drug Administration (FDA) recently approved Qsymia (phentermine and topiramate extended release) and Belviq (lorcaserin hydrochloride) weight loss pills for management of obesity.
62%-69% of patients that received Qsymia lost an average of 5% body weight in comparison to 20% that received placebo. In patient without type 2 diabetes, 47% lost an average of 5% bodyweight compared to 23% on placebo.
In patient with type 2 diabetes, 38% lost average 5% of bodyweight compared to 16% in placebo. The epidemic of obesity threatens the overall wellbeing of patients, especially for those with co-morbidities. The material on this site is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.
The content on this website is for information only and is not a substitute for professional medical advice, diagnosis, and treatment. As for her weight loss a year later, Amanda says she fluctuates between gaining and losing about 12 lbs. For the best WordPress experience, please update your browser or learn how to browse happy! However, it will not help you with some underlying condition that your obesity might be related to. First of all, phentermine might be habit-forming and it should be taken only by the person for whom it is prescribed. You should likewise be very cautious about interactions between Qsymia and other medicines you use.
Alcohol must not be one of them, however, since it might increase the Qsymia’s side effects.
Although both drugs are designed to help people lose weight, they are nonetheless quite different.
Different limitations of use might be considered as a criterion of choice between Qsymia and Belviq, since they have never been tested in a head-to-head clinical trial and there is no data demonstrating which one is more effective. Qsymia cost is around $75 for 30 days of the recommended dose (or $35 for patients with insurance). Thata€™s the debate sparked by federal approval of Qsymia as a prescription drug for weight loss on July 17. Food and Drug Administration (FDA) initially rejected the drug in 2010, but relented after reviewing new data presented by the manufacturer this year.
The drug can cause birth defects if taken early in a pregnancy, even before a woman realizes shea€™s pregnant. Fifty percent of patients we see get prescribed anti-obesity medications in addition to diet and exercise, and we see 450 patients per month. We need more drugs for obesity, as many drugs as there are for type 2 diabetes and hypertension. So women of childbearing age and people at risk of cardiovascular disease should watch out.
Weight-loss drugs work if used properly and with diet and exercise and behavioral modification of lifestyle. We are seeing drugs becoming available because doctors, laypeople, the FDA, and the research community are realizing that obesity causes much disease and mortality. If a patient becomes pregnant while taking Qsymia, treatment should be discontinued immediately, and the patient should be informed of the potential hazard to the fetus.
Diabetes, high blood pressure, cholesterol, joint injury and pain, and heart disease are all real and serious problems associated with excess weight. It doesn’t treat low access to healthy food and greenspace, fitness deserts, unhealthy school lunches, confusing or misleading labels, crappy additives, or a generally sedentary lifestyle. Use of the web site constitues acceptance of the Defy Media Terms of Use and Privacy Policy. Prescription medication may be used for a short period of time while you are starting your weight loss program at QMed or it may be a piece of a larger discussion to help you achieve your goals.A  Each person and situation is different and our medical Providers have the experience and expertise to discuss is a prescription weight loss drug is right for you.
SSRIs (selective serotonin reuptake inhibitors) are a group of drugs that are mainly used to treat depression, but it has been found that many of the drugs that affect neurotransmitters have lots of other affects, change in appetite is one of the effects.


It may work by decreasing your appetite, affecting parts of the brain or increasing the amount of energy used by the body.
Most people’s weight tends to level off after six months while taking a weight loss medication.
Most side effects of weight loss drugs are mild (although some can be unpleasant) and usually improve as your body adjusts to the medication. Because some appetite suppressants may cause drowsiness or lightheadedness, it is important to know how you respond to these medications before you attempt to drive or operate machinery. Both Qsymia and Belviq are combined with a reduced calorie diet and exercise for long term weight management in adult patients with a body mass index (BMI) of 30 or greater or adult overweight patients with at least one weight related condition such as high blood pressure, type II diabetes, or high cholesterol. The first component is a migraine and seizure medication called topiramate that causes weight loss by reducing appetite, increasing feelings of fullness, reducing the taste of food, and increasing burning of calories. Belviq possibly decreases food consumption by making a person feel full even after consuming less food than usual.
With the FDA approval of Qsymia and Belviq weight loss pills, patients who are obese can potentially benefit from these two therapies. Although sometimes it is prescribed in cases where obesity is related to diabetes, high cholesterol or high blood pressure, Qsymia will only cause weight loss and will not treat any of other mentioned conditions.
Both substances were clinically tested and confirmed to be effective when used in a proper way. It is also advised to refrain from driving or performing any other activities that require to be alert.
Notwithstanding, both drugs require a proper diet and physical activity for achieving best results. Caroline Apovian, who heads Boston Medical Centera€™s Nutrition and Weight Management Center. The trial results of Qsymia produce the best weight loss we have seen since the era of Fen-Phen. And topiramate, which is actually an anti-seizure medication, has been prescribed off-label by doctors for weight loss reasons, because it increases feelings of fullness and makes food taste less appetizing. This leads to a concern that the person has developed a tolerance for the medication, but this is unclear. This article will highlight some distinguishing facts about the two medications so that patients and physicians can make an informed decision when selecting a weight loss pill. The second component is called phentermine, which suppresses appetite by triggering the release of a brain chemical (hormone) called leptin, which regulates appetite. It may work by increasing levels of serotonin, a neurotransmitter (brain chemical) that nerves use for communicating.
Discontinue therapy if a patient has not lost at least 5% from baseline bodyweight by week 12. However, important practices and monitoring is extremely critical to ensure the safety and efficacy of both medications. It is also very important that women who are pregnant or are planning to get pregnant should not take Qsymia, as it may lead to birth defects. Higher doses of this drug might have effects similar to those of hallucinogenic drugs like LSD. In fact, the School of Medicine associate professor has already prescribed a medication thata€™s a component of Qsymia for some of her patients. We have safer surgeries available, diet and exercise, behavior, and some medications coming outa€”a confluence of treatments that can be used concomitantly to treat both type 2 diabetes and obesity.
To dispense Qsymia, pharmacies and prescribers must be certified through special training and a Risk Evaluation and Mitigation Strategy (REMS) program must be followed. It is designed to help obese and some overweight adults in losing weight as well as keep the weight off. Last but not least, you should strictly follow instructions on your doctor’s prescription label and consult with her or him when your organism reacts in an unexpected way.
She actually lost the weight last year and posted pictures about it, but a recent animated time lapse (gif) lasting about five seconds ans showing her transformation has now sent the story viral. We also have a certification exam for obesity medicine starting in November of this year; we have created a new sub-specialty called obesity medicine. This will enable primary care physicians and other specialties to have skills so that they can manage obesity and the medications being approved for it.



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