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Thyroid cancer new drug lenvatinib is bringing hope to patients with a progression-free survival almost five times more in people who receive the treatment. Lenvatinib oral medication fights cancer by deterring the development of new blood vessels that can feed it, according to researchers. For metastatic thyroid cancer, the first treatment option is thyroidectomy, either partial or total. The thyroid cancer new drug lenvatinib, which is bringing more hope to patients, has still to get the approval of the Food and Drug Administration of the U.S. From 21 countries, nearly 400 thyroid cancer patients who have become radioactive iodine-resistant enrolled for the lenvatinib international clinical trial.
More than half of the patients treated with lenvatinib responded partially or fully, with a dramatic 65 percent response rate, said Sherman.
Like any other drug, with the targeted effects of lenvatinib will come unwanted side effects. According to the study, there were side-effects related deaths, like, six out of 20, during the period of lenvatinib treatment.


The thyroid cancer new drug lenvatinib which is supposed to bring more hope to patients, will indeed pose health risks as well, with its potential life-threatening side effects, but Sherman and Masters said there are ways to deal with the side effects, like dosage adjustment, or by treating the side effects individually.
If you or a loved one has cancer, do not continue to feed and encourage the tumor growth! According to new clinical trial results, the drug can delay the progression of the disease by 18 months more than a placebo in those with recurring thyroid cancer.
The results of Eisai-funded Lenvatinib study were published in the New England Journal of Medicine in its February 12 issue. Steven Sherman, the study leader, patients with advanced thyroid cancer historically only have radioactive iodine.
Radioiodine therapy usually follows surgery as well, but since the cells of thyroid cancer mostly become non-absorbent of iodine, radioiodine therapy’s effectiveness is limited in most metastatic thyroid cancer.
Gregory Masters of Newark’s Christiana Care Health System, said the new targeted therapies are inspiring in the advancement of patient treatment.
Masters believes that the medication can improve the overall survival of the patients, considering it is effective in stalling the development of the cancer.


Patients under lenvatinib medication experienced reactions, such as hypertension, diarrhea, loss of appetite, fatigue, decreased weight and nausea. There is still a need though to check on how the medication will impact the patient’s quality of life. Their primary cancers were located in the breast, brain, lungs, kidneys, pancreas, esophagus, stomach, colon, prostate, ovaries and skin. Yet, the treatment does not work with more than half of the patients, making it less and less effective. Masters, who was not part of the study, expressed that this is an achievement of a greater understanding about thyroid cancer growth, and on getting knowledge to block its pathways.



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