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Breast cancer remains one of the most prevalent types of cancer, but a new study in Canada shows that recurrence rates have at least been halved since the 1980s, thanks to early detection and improved treatment options.
Published in the Journal of Clinical Oncology, the study examined data on 7,178 women who underwent treatment for early to moderately advanced breast cancers from 1986 to 1992 and 2004 to 2008. HER2 deserves attention because it is a component that drives the growth of cancer cells; not to mention that tumors with HER2 have the tendency to be much more aggressive than those without the protein.
In the study, it was shown that the overall risk of breast cancer recurring in women in the second group was 50 percent lower compared to the earlier group, for every year after they are declared cancer-free. Cases involving HER2-positive cancers also showed the most reductions in risk of recurrence. Researchers were not able to show how recurrence rates were improving but they believe it is most likely due to technologies that improved screening procedures, which ultimately improved early detection rates.
The study titled "Comparison of Breast Cancer Recurrence and Outcome Patterns Between Patients Treated From 1986 to 1992 and From 2004 to 2008," was carried out by Yvonne Zheng, Caroline H. The bowel cancer death rate in the UK is falling faster than in most other EU countries, according to a new study published in the British Medical Journal. Changes in bowel cancer death rate by age and sex were evaluated in 34 EU countries between 1970 and 2011. From 1989 to 2011 in all countries death from bowel cancer increased by an average of 6% for men and decreased by an average of 15% for women.
But in the UK, reductions in bowel cancer death rates of more than 25% in men and 30% in women were recorded. The increased survival is also due to high levels of screening, particularly endoscopic screening, which allows specialists to look inside the lower bowel and remove any small growths called “polyps”, which can become cancerous if left untreated.
The other bowel cancer screening option available to adults in the UK is a faecal occult blood (FOB) test, which checks for the presence of blood in a poo sample – a potential early sign of the disease.


Starting from the mid-1980s, incidence rates declined for both sexes until the mid-1990s (although this decline was more prominent for females). The CCAC is emphasizing more than ever the importance of primary prevention and timely screening.
If you are between the ages of 50-74 and are of average risk, it is important that you be screened at least every two years with a fecal occult blood test (FOBT) or fecal immunochemical test (FIT). Among Canadians alive on January 1, 2009, just over 810,000 had been diagnosed with cancer in the previous 10 years. As of 2009 there were approximately 105,195 individuals (56,650 men and 48, 545 women) with colorectal cancer who were diagnosed in the 10 previous years i.e.
This year there will be approximately 9,300 Canadians who will die from the disease (about 5,100 (55%) men and 4,200 (45%) women). Colorectal cancer is the second most likely cause of death for males with a 1 in 29 chance of dying from it.
Colorectal cancer mortality rates are highest in Newfoundland and Labrador for both males and females (which also has the highest incidence rate of colorectal cancer for males and females).
The Relative Survival Ratios (RSRs) for colorectal cancer range from 60% to 62% in all provinces except Ontario (67%).
RSRs for colorectal cancer are consistent at 68% among people diagnosed between the ages of 15 and 69 years; RSRs then decrease with advancing age. Survival improvements in prostate and colorectal cancers are due to increased use of Screening and early detection that have helped identify cancers at a treatable stage.
The incidence of colorectal cancer in Canada is highest for men and women in Newfoundland and Labrador.
By 2028 -2032 it is estimated that colorectal cancers will increase to 35,015 new cases from what was 19, 630 in 2003 -2007.


It is projected there will be a net increase in prevalence from 2015 to 2030 with FIT due to the detection of cancers at earlier stages and improved survival among patients.
Between 2015 and 2030, a biennial FIT screening program with a participation rate of 30% could lead to 21,000 cumulative deaths averted compared to 40,000 cumulative deaths averted with a participation rate of 80%. 770 estimated new colorectal cancer cases (430 men and 340 women) with 280 estimated colorectal cancer deaths (160 men and 120 women). Cancer characteristics were matched from each period, including the presence of a protein called HER2 and the status of estrogen receptors.
Together with the detection of cancers in their early stages, targeted therapies were able to improve overall survival rates for cancer because they allowed drugs to work better at fighting cancer. For instance, a woman with a recurrence risk of 23 percent for the first period only has to deal with a nine percent recurrence risk on the second period. Karen Gelmon, the study's lead author, analyzing data on breast cancer patients in Canada not only provided reassurance that survival rates are improving but also gave researchers valuable data to use in their studies. There was also the fact that advancements in technology translated to advancements in treatment, allowing for more comprehensive and targeted approaches that make it possible to combat specific types of cancer. Incidence rates then rose through 2000, only to decline slightly thereafter, most likely due to increased use of colorectal cancer screening, which can identify and remove precancerous polyps, which can in turn reduce incidence.
The decline in colorectal cancer incidence rates appears confined to older adults as rates are increasing among young adults under the age of 50 years in Canada and in the United States. Participation rates vary within and between the existing organized programs and do not meet the target of 60%.



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