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Nongonococcal urethritis and chlamydial cervicitis are sexually transmitted diseases usually caused by Chlamydia trachomatis or (in men) Ureaplasma urealyticum but occasionally by Trichomonas vaginalis or herpes simplex virus.
These infections are called "nongonococcal" to indicate that they aren't caused by Neisseria gonorrhoeae, the bacterium that causes gonorrhea.
Usually between 4 and 28 days after intercourse with an infected person, an infected man feels a mild burning sensation in his urethra while urinating.
Although most women infected with Chlamydia have no symptoms, some have a frequent urge to urinate, pain while urinating, pain in the lower abdomen, pain during sexual intercourse, and secretions of yellow mucus and pus from the vagina. In most cases, an infection with Chlamydia trachomatis can be diagnosed by examining discharge from the penis or cervix in a laboratory.
If an infection caused by Chlamydia trachomatis isn't treated, symptoms disappear in 4 weeks in about 60 to 70 percent of the people. If untreated, a chlamydial infection in women often ascends to the fallopian tubes, where inflammation may cause pain, and scarring may cause infertility and ectopic pregnancy.
Chlamydial and ureaplasmal infections are usually treated with tetracycline or doxycycline taken orally for at least 7 days or with a single dose of azithromycin.
Infected people who have sexual intercourse before completing treatment may infect their partners.
Trichomoniasis is a sexually transmitted disease of the vagina or urethra caused by Trichomonas vaginalis, a single-celled organism with a whiplike tail.
Although Trichomonas vaginalis can infect the genitourinary tract of either men or women, symptoms are more common in women. In men, the organism infects the urethra, prostate, and bladder, but it only rarely causes symptoms. In women, the diagnosis can usually be made within minutes by examining a sample of vaginal secretions under a microscope. In men, secretions from the end of the penis should be obtained in the morning before urination. A single oral dose of metronidazole cures up to 95 percent of infected women, provided their sex partners are treated simultaneously Because it's not known whether a single-dose treatment is effective in men, men are usually treated for 7 days. Metronidazole is probably best avoided during pregnancy, at least during the first 3 months.
Genital candidiasis is a yeast (fungus) infection of the vagina orpenis, commonly referred to as thrush, caused by Candida albicans. Women with genital candidiasis usually develop itching or irritation of the vagina and vulva and may have a vaginal discharge.
Men often have no symptoms, but the end of the penis (the glans) and the foreskin (in uncircumcised men) may be sore and irritated, especially after sexual intercourse. In women, candidiasis can be treated by washing the vagina with soap and water, drying it with a clean towel, and then applying an antifungal cream containing clotrimazole, miconazole, butoconazole, or tioconazole and terconazole. Occasionally, women who take oral contraceptives must stop using them for several months during treatment for vaginal candidiasis because they can make the infection worse.
According to the Centers for Disease Control (1993) there are 12 million cases of sexually transmitted disease (STD) cases reported annually. In healthy people, urine in the bladder is sterile; no bacteria or other infectious organisms are present. Sexually transmitted diseases are infections that are often, if not always, passed from person to person through sexual contact. The objective of this study was to investigate the clinical features of non-gonococcal urethritis in men who attended a urological outpatient clinic in Japan. This study included a total of 194 patients diagnosed as having non-gonococcal urethritis and subsequently judged as cured following antibiotic therapy between January 2001 and June 2005. The incubation period in the CU group was significantly longer than that in the NCU group (P = 0.0020). These findings suggest that the clinical characteristics of CU and NCU clearly differ and that CU tends to require a longer time to cure than NCU; therefore, among patients with non-gonococcal urethritis, it would be particularly important to effectively control the spread of CU.
JavaScript is currently disabled, this site works much better if you enable JavaScript in your browser. Almost all physicians involved in treating sexually transmitted infections recognize the specific clinical manifestations of patients with urethritis. The epidemiology of nongonococcal urethritis (NGU) refers to the study of NGU as it occurs in populations of men, while etiology encompasses study of microbial as well as nonmicrobial causation. The aim of this study was to confirm the clinical efficacy of a single-dose azithromycin (AZM) regimen (1000 mg) for patients with nongonococcal urethritis in real-life practice.
Fertility and sexual health Information about changes in sexual health and fertility. In the United States there are approximately 800,000 reproductive-aged men and women who have cancer, many of whom have concerns about their fertility. I have been trying to conceive for two years now and recently I read an article about dysmenorrhea. A new ELISA-based hormonal test, measuring the levels of Inhibin B in serum on day 3 of the menstrual cycle. Part of what makes understanding fertility so difficult is that there are so many aspects that need to be considered, from sperm motility to egg quality and everything in between.

When you complain of burning on urination, feeling like you have to urinate all the time, getting up in the night to urinate or having urgency to urinate when your bladder is full because it hurts so much, you usually have a urinary tract infection.
FSH, HCG, and HMG are abbreviations for three different medications used to treat infertility.
Normal ovulation is a complex process that requires many things to happen properly and at the correct time with the proper hormone levels. I am a 26 year old woman, I already have one son whom I conceived naturally without any medication. A balanced translocation is a condition in which the correct number of chromosomes are present, but two pieces of chromosomal material have switched places.
Dealing with infertility is particularly difficult because couples find that they are no longer in control of their reproductive choices. Klinefelter's syndrome only occurs in males and results from a congenital abnormality of the sex chromosomes, X and Y. Chlamydia trachomatis causes about 50 percent of the urethral infections in men not caused by gonorrhea and most of the pus-forming infections of the cervix in women not caused by gonorrhea. Ureaplasmas are very small bacteria that lack a rigid cell wall but that can reproduce outside cells. Ureaplasma urealyticum infections are not diagnosed specifically in routine medical settings.
These latter complications may occur in the absence of prior symptoms and result in considerable suffering and medical costs. About 20 percent of women experience trichomoniasis of the vagina during their reproductive years. In some populations, Trichomonas may account for 5 to 10 percent of all cases of nongonococcal urethritis.
Some men have a temporary frothy or pus-like discharge from the urethra, pain during urination, and a need to urinate frequently. The secretions are examined under a microscope, and a sample of the secretions is sent to the laboratory for culture. The drug also may cause a decrease in white blood cells and, in women, an increased susceptibility to vaginal yeast infections (genital candidiasis).
Infected people who have sexual intercourse before the infection is cured are likely to infect their partners. Genital candidiasis has become more common mainly because of the increasing use of antibiotics, oral contraceptives, and other drugs that change the environment in the vagina in a way that favors the growth of Candida. Women who are at unavoidable risk of vaginal candidiasis, such as those who have an impaired immune system or who are taking antibiotics for a long period of time, may need an antifungal drug or other preventive therapy.
Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.
Clinical data were analyzed after dividing these patients into two groups as follows: 96 patients with chlamydial urethritis (CU) and 98 with non-chlamydial urethritis (NCU). However, in previous studies, the diagnosis of gonococcal urethritis was based on cultures or staining methods. The meager existing state of knowledge about NGU dictates that epi­demiologic studies of NGU be linked closely with studies of causa­tion.
The study finally evaluated 55 patients, 42 who were symptomatic and 13 who were asymptomatic, after excluding 40 who visited clinics only once.
Since only the Follicular Granulosa cells secrete this hormone, its level reflects on the potential of the ovary to grow follicles, which physicians refer to as 'ovarian reserve'. Cervical mucus, a jelly-like substance produced by glands in the cervical canal, is a factor in a woman's fertility. The individual who has a balanced translocation usually appears completely normal and healthy, but when a carrier attempts to have children, that is when problems are encountered. They can't decide when to have a baby, how many they will have, or how far to space children apart. Normally a male has only one X and one Y chromosome and a female has two of the X-chromosomes.
Most of the remaining cases of urethritis are caused by Ureaplasma urealyticum, a mycoplasma-like bacterium. Be-cause culturing is difficult and other techniques for diagnosis are expensive, the diagnosis of Chlamydia or Ureaplasma infection often is presumed on the basis of the characteristic symptoms along with evidence against the presence of gonorrhea. In men, Chlamydia may cause epididymitis, which produces painful swelling of the scrotum on one or both sides.
The vulva (the external female genital organs) may be irritated and sore, and sexual intercourse may be painful. A urine culture may also be helpful, because this is more likely to detect Trichomonas missed by microscopic examination. The end of the penis and the foreskin may be reddish, may have small crusted blisters or sores, and may be covered with white cheese-like material. In men, the penis (and foreskin in uncircumcised men) should be washed and dried before an antifungal cream (containing, for example, nystatin) is applied.
In this study, we examined in detail the clinical manifestations of patients with urethritis diagnosed by the nucleic acid amplification test (NAAT).

Current interest is stimulated by the increasing incidence of NGU apparent in many countries. Sixteen of the symptomatic patients were diagnosed as having nongonococcal chlamydial urethritis, 7 as having nongonococcal nonchlamydial urethritis, and 19 as having urethritis without any microbial detection.
About two weeks ago I had a laparoscopy with tubal lavuge and laser surgery, and the outcome was this: I have severe endometriosis and blocked tubes.
It's the only simple explanation I have as to why some folks must endure rigorous testing, invasive procedures, drugs and, sometimes, pure utter emotional hell in their efforts to conceive a child, while others can practically just look at each other and - Poof!
In Klinefelter's syndrome, two or more X-chromosomes are present in addition to one Y chromosome. Early in the morning, the opening of the penis is often red and stuck together with dried secretions. The urethra may be mildly irritated, and occasionally moisture appears at the opening of the penis. Less commonly, the use of drugs (such as corticosteroids or cancer chemotherapy) and diseases that suppress the immune system (such as AIDS) can facilitate the infection.
Immediate diagnosis can be made by taking specimens from the vagina or the penis and examining them under a microscope. The duration of antibiotic therapy until cured was significantly longer in the CU group than in the NCU group (P = 0.0051). This interest is further heightened by the wide range of opinions concerning NGU which are firmly held by practicing physicians. Chlamydia trachomatis was detected in 11 asymptomatic patients, Mycoplasma genitalium in 1, and Ureaplasma urealyticum in 1. As tubes become damaged they are still able to secrete fluid but can no longer reabsorb it.
Pain on urination or frequency of urination may occur, resembling the symptoms of a bladder infection. The vaginal wall is usually covered with a white cheese-like material, but it may look normal. Furthermore, multivariate analysis showed that whether the infection involved CU or NCU was independently associated with the treatment interval irrespective of other factors examined (P = 0.041). The NAAT could distinguish 64 patients with gonococcal urethritis, 45 patients with chlamydial urethritis, and 45 patients with nongonococcal and nonchlamydial urethritis.
Opinions differ on such basic issues as whether the syndrome is or is not usually sexually acquired, whether it is infectious or noninfectious, and what microbial pathogens might cause it. The man finds urinating painful, needs to urinate frequently, and has discharges of pus from the urethra. These differences are due to the lack of controlled research employing concomitant epidemio­logic and etiologic study methods until very recently. The clinical cure rate was 86% for the 42 symptomatic patients with detectable and undetectable pathogens. Phylogeny-based rapid identification of Mycoplasma and Ureaplasma from urethritis patients.
There were 39 (86.7%) patients in the chlamydial urethritis group with mild symptoms, clear discharge or none, and moderate or profuse discharge. This paper presents a preliminary analysis of a cohort study of the epidemi­ology of NGU, conducted by the U.S. Although the diagnosis of male urethritis can be performed by microbiological examination, the typical symptoms help us to distinguish each type of urethritis and understand this kind of disease.
In conclusion, the single-dose AZM regimen was well tolerated and eradicated the estimated and potential pathogens of nongonococcal urethritis. A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis.
Navy, and the University of Washington; and a review of case-control studies of the etiology of NGU, conducted in London and Seattle.
Sex Transm Infec 80:289–293CrossRef9.Hocking J, Fairley CK (2005) Do the characteristics of sexual health centre clients predict Chlamydia infection sufficiently strongly to allow selective screening?
Basic and clinical studies of azithromycin for the treatment of sexually transmitted male urethritis (in Japanese).
Mycoplasma genitalium as a sexually transmitted infection: implications for screening, testing, and treatment.
Antibiotic susceptibility testing of Mycoplasma genitalium by TaqMan 5? nuclease real-time PCR. Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum DNAs in urine from asymptomatic healthy young Japanese men. A randomized, double-blind study comparing single-dose rifalazil with single-dose azithromycin for the empirical treatment of nongonococcal urethritis in men. Treatment of men with urethritis negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum.

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