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Background: Daily oral preexposure prophylaxis (PrEP) using the antiretroviral tenofovir disoproxil fumarate (TDF) alone or in combination with emtricitabine (FTC–TDF) reduces the risk for HIV-1 acquisition.

Daily Oral Tenofovir and Emtricitabine–Tenofovir Preexposure Prophylaxis Reduces Herpes Simplex Virus Type 2 Acquisition Among Heterosexual HIV-1–Uninfected Men and Women: A Subgroup Analysis of a Randomized Trial.
A total of 131 participants seroconverted to HSV-2 (42 in the tenofovir group, 37 in the FTC–TDF group, and 52 in the placebo group) and were included in the intention-to-treat analysis.
Data set: Portions of the analytic data set are available to approved individuals through written agreement with Dr.

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