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Signs herpes outbreak is coming

Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. One of the most difficult aspects of living with herpes is the knowledge that it’s with you forever. Antiviral drugs are most often prescribed to treat herpes today, such as acyclovir and famciclovir, while they effectively suppress the symptoms of an active herpes infection, the medications do little to inhibit viral shedding. However, the advent of research and latest technology has helped experts to have finally aced the possible cure for herpes – with better and promising treatment of existing herpes infections, and experimental vaccines to prevent infections from occurring. Pritelivir, a new antiviral drug that attacks the HSV early in the replication process, has shown some great initial results. Additionally, since this drug works differently than antivirals already approved for use, it may provide a weapon against drug-resistant herpes viruses. At Duke University, studies have focused on the herpes virus’ unique ability to lie dormant in the body for extended periods of time, and then reactivate. The key to making this research into a viable herpes treatment, according to researchers, will be in learning how to use single strands of RNA, called microRNA, to activate the dormant virus, thereby making them vulnerable to antiviral drugs. Researchers at the University of Florida are taking a similar approach to combatting viral infection. Using a specially created RNA enzyme called a hammerhead ribozyme, researchers were able to keep the virus from reactivating in test animals. In this rather complex study, researchers at Albert Einstein College of Medicine of Yeshiva University addressed the process of viral cell penetration – a step earlier in the infection process than either viral replication or shedding.
They identified one molecule, Akt, as providing the critical signal that starts the infection process. These innovative cures for herpes are encouraging, but what’s truly exciting is the possibility of a herpes vaccine. Much like pritelivir, the experimental vaccine HerpV focuses on viral shedding as the crucial function to suppress.
Perhaps even more interesting are the results of early clinical trials for a vaccine currently called GEN-003. Reports from Genocea, the company developing the vaccine, also indicate measurable increases in the immune response of T-cells, which are known to be instrumental in fighting off various diseases and infections.
While classified as vaccines by their developers, HerpV and GEN-003 are still mostly targeted at responding to the symptoms of an active infection.
The first of these trial vaccines is currently called HSV529, and it’s being developed by the National Institute of Allergy and Infectious Diseases (NIAID).
What’s different about the Coridon vaccine, though, is the way that response is being created. Phase 1 trials appear to have been successful, and a second round of trials is in the works.
Many of these natural remedies have proven to be highly effective when used to heal herpes sores and decrease the number and frequency of herpes outbreaks. The connection between the amino acids lysine and arginine and herpes activity is fairly well documented. A resin made by bees, propolis is full of immune-boosting, infection-fighting antioxidants and flavonoids. Bee propolis is an extremely safe antibacterial and antiviral that can be used anywhere on the body (except for the eyes) with one major exception: people who are allergic to bee pollen or who suffer from asthma should not use propolis, as it can cause an allergic reaction. Chinese herbalists have known the anti-inflammatory and antiviral properties of black tea tannins for thousands of years.
Taking liquid Siberian ginseng extract is a great way reduce the duration and intensity of genital herpes outbreaks. This popular remedy for the common cold does seem to offer some protection against viral infection.
Another standby of Chinese herbal medicine, licorice root has long been used to treat herpes, shingles, and cold sores. This gentle, effective antiviral can be used as a topical treatment four or five times a day. While it may be risky to ingest high doses of zinc regularly, in a cream or ointment zinc (often sold as zinc oxide cream) is a well-known and effective treatment for herpes sores. Melissa officinalis, or lemon balm as it’s commonly called, is a versatile and proven antiviral and one of the most effective topical treatments for herpes sores. Lemon balm, when applied directly to sores, is a great painkiller as well as an effective healer.
A relative newcomer to the herpes treatment scene, red marine algae (Gigartina) has shown the ability to stimulate immune response, lessening the intensity and frequency of herpes outbreaks.
Long used as a home remedy for burns and cuts, aloe vera has also shown promise as a topical treatment for genital herpes, especially for men. When you’re suffering from a painful, itchy genital herpes outbreak, one of the most soothing remedies possible is a simple bath in warm water infused with Epsom salts.
Along with Epsom salts, baking soda is a safe, inexpensive way to dry out herpes lesions, relieve pain and itching, and speed healing. The best times to apply baking soda to sores are after a shower, so that sores are softer and more absorbent, and before going to bed, so the baking soda stays put. This is a good news, although as I noticed, those promising cures keep coming out each year and disappear one by one. Information provided on this site is not intended as a substitute for medical advice on any health concerns you may have. At the initial phase, the viruses move towards the sensory nerves and they become latent here and reside here for life.
The drug known by its generic name, Acyclovir, belongs to the synthetic nucleoside analogues group of drugs used primarily to treat particular viral infections.


Manufactured by GlaxoSmithKline and marketed as Zovirax, it comes in liquid, capsule and tablet forms. But acyclovir remains the oldest form of treatment for the herpes simplex 1 and simplex 2 viruses, or cold sores and genital herpes, which cause infections in those afflicted with HIV. When a virus takes over a living cell and reproduces itself, at the host cell’s expense, acyclovir is converted into an activated form by the same virus, enabling it to use acyclovir’s active form instead of the nucleoside which it normally uses in the manufacture of DNA; DNA is a crucial element in the replication of a virus. Simply put, cells which have been virally infected tend to absorb more of the acyclovir than their normal counterparts; therefore there is more conversion of it into active forms, a condition which helps prolong the anti-viral activity. Acyclovir is not a curative treatment for viral infections but it can shorten the duration of the infections and lessen their possibility of developing into more serious medical conditions. In initial cases of genital herpes, acyclovir helps reduce lesions and decreases severity and frequency of infections which are recurrent.
Depending on the severity of the genital herpes infection of an individual who has it for the first time, an oral dosage of acyclovir at 400mg thrice a day has been recommended by the CDCP or Center for Disease Control and Prevention; this dosage has to be ingested between seven and ten days.
The patient may then choose to have daily or episodic therapy; the former is also known as suppressive therapy. Patients who have existing conditions of HIV should take 400mg of oral acyclovir thrice a day between five and ten days. While there haven’t been sufficient clinical studies on the use of acyclovir by pregnant women and subsequent adverse effects, nursing women are cautioned against ingesting acyclovir since this can be transferred to an infant as an excretion in breast milk. All prices provided on this website are estimates only and will vary depending on your insurance and location.
While there are many ways to treat the symptoms of the herpes simplex virus (HSV), there are no cures yet. Furthermore, they are effective only in treating cells that are already infected with the virus.
The news is good for several reasons: First, subjects taking pritelivir experienced dramatically less viral shedding than the control group in the study. It’s also possible that pritelivir could be used in combination with current drugs to deliver a powerful one-two punch to HSV. Since current treatments only apply to active viruses, these latent viruses survive despite drug therapy. Their work also focuses on the herpes virus’ ability to reactivate and recur over time.
If the technique works equally well for humans, this gene therapy will keep the virus from causing repeated herpes outbreaks. By inhibiting the body’s production of Akt, they were able to significantly reduce herpes infections in human cells exposed to the virus.
A vaccine has the potential to nearly eradicate a disease, by helping the body to develop an immunity to a specific infection. This vaccine also demonstrated positive reductions in viral shedding – in some cases shedding was reduced by as much as 50%.
There are, however, two vaccines in the very early stages of clinical trials that are aimed directly at preventing a herpes infection from ever taking hold in the body. The vaccine is the result of a 10-year partnership between doctors at Harvard Medical School and the NIAID. If successful, the altered virus will stimulate immune responses in the body that will prevent infection from active HSV.
Research for the vaccine is being conducted by Coridon, an Australian biotech company working in conjunction with the University of Queensland. Instead of introducing a weakened version of the herpes virus, this vaccine uses a small section of DNA to produce T-cells and stimulate the immune response.
Researchers at Coridon, however, emphasize that even in the most ideal of circumstances, they’ll need between 6 and 10 years of further studies before their vaccine becomes commercially available. But those who are already dealing with a herpes infection understand the importance of living in the present. Arginine seems to promote the formation of herpes sores, while lysine tends to prevent herpes breakouts and also helps to heal existing sores quickly. You’ll find propolis in ointments, lotions, and even some high-quality organic honeys. It’s taken Western medicine a while to catch up, but recent studies now appear to confirm the healing powers of black tea. Just brew a cup of black tea, let the tea bag cool until you can touch it comfortably, and apply the tea bag directly to a herpes lesion. Ginseng is known to have the ability to strengthen the immune response, which may make it helpful in fighting off the effects of an active herpes episode. Liquid extract of licorice root can be applied directly to herpes sores; you can also make a paste with powdered licorice root and almond oil. It reduces healing time dramatically, and can also lower the stress levels that incite herpes outbreaks. Aloe vera is readily available in creams and gels – you can even keep an aloe plant growing in your home and break open one of its thick leaves for an easy source of this useful substance.
The Epsom salts ease the pain of inflamed tissues and dry out herpes sores, helping them to heal faster. For best results, cover a cotton ball completely with baking soda, and apply it directly to the sore. After a certain period of time, the occurrence of active period reduces in frequency and even if it occurs the severity is less. Take 5.5 liters of water and add to it one oz of marsh mallow roots, one oz of mullein and one oz of mallow. Calendula or hypericum ointment is very effective in the treatment of herpes and gives a soothing effect.


Prepare an ointment by adding lavender oil and bee wax to a cup of olive oil and cooking the ingredients for some time.
Intake black coffee without sugar and the remains of the coffee can be applied to the blisters for relief. Acyclovir is a prescriptive medication that prevents the division and multiplication of viruses responsible for said infections.
When the active acyclovir is incorporated into a new virus in the DNA, production of DNA stops. Taking acyclovir for treatment of genital herpes can help reduce its severity or prevent it from further recurrences.
The latter is experienced as a painful rash which could develop several years after having had chicken pox with the reactivation of the virus. For shingles, acyclovir helps reduce pain, shorten the duration for healing, and halts the formation of more lesions and further spread of the virus. Acyclovir may be used intravenously for patients who have severe cases of genital herpes as well as those whose immune systems are compromised. Those who elected episodic therapy can choose to take acyclovir orally at 400mg thrice daily for a total of five days, 800mg thrice daily for a total of two days or 800mg twice a day for a total of five days. For suppressive therapy, the CDCP recommends 400mg of oral acyclovir twice daily; those who are already infected with HIV should take it between 400mg and 800mg two or three times daily.
In males the inflamed organs comprise glans penis, penis shaft, inner thighs, buttocks or anus; whereas in females the organs affected are pubis, labia, clitoris, vulva, buttocks or anus.
That’s why many medical researchers consider the search for a herpes cure to be akin to the search for the Holy Grail.
Rather than seeking to activate the latent herpes virus, however, this study seeks to keep it dormant and thereby eliminate the possibility of recurring infection. And, like pritelivir, it will provide an alternative to drugs that viruses already tolerate. Later, if the virus is re-introduced, production of those antibodies is stimulated and the body is able to stave off infection. But widespread use of vaccinations gradually decreased incidences of this disease, and the last known case of polio in the U.S.
Patients in these studies experienced a 15% reduction in viral shedding while taking no additional antiviral medications. Study of the vaccine is in the early trial stage, and researchers hope to complete this initial phase some time in 2016. And for the present, there are two main approaches to managing the symptoms of HSV: medical treatment with prescription drugs like acyclovir, famciclovir, or valacyclovir, or with natural remedies. Avoid taking higher doses of lysine for extended periods of time, as it may raise cholesterol levels and increase the amount of calcium your body absorbs. As a topical treatment for herpes lesions, propolis has proven to be a quick and effective healer. The recommended dosage is one-half to a full tablespoon three times daily during a herpes outbreak.
There’s not a lot of evidence, however, that echinacea is effective when used as a herpes treatment.
Either way, it’s made from lauric acid, which is a component of both coconut oil and human breast milk. That’s why it may be easier to take a supplement in concentrated form, as lauricidin. FDA (Food and Drug Administration) approved the drug for use against the virus known as varicella-zoster in the treatment of viral infections which caused shingles and chicken pox.
A study published last year, however, revealed that herpes strains which are resistant to acyclovir could develop over a certain period of time. Aside from acyclovir’s availability in 200 mg capsules, 400mg and 800mg tablets, and 200mg and 5ml liquid suspension, it is also available as a 50mg or 40ml injection, a 500mg and 1000mg powder and as 5% ointment. There have been reports of seizures, hepatitis, agitation, hypersensitivity reaction, muscle pain, and anemia, all of which must be reported to the patient’s doctor for advisement.
Bonus: black tea is a great source of caffeine, so enjoy a little pick-me-up by drinking the tea while treating a herpes sore with the tea bag. Doctors have also prescribed acyclovir in the treatment of the Epstein-Barr virus which causes mononucleosis. Female also have additional symptoms of painful urination or dysuria, and cervicitis. As the condition is fast going on assuming epidemic proportions among the world population, mainstream medicine just does not have any cure for the disease.
However there are some drugs which can shorten outbreaks making them less severe, like acyclovir, valacyclovir and famciclovir. As the condition is fast going on assuming epidemic proportions among the world population, mainstream medicine just does not have any cure for the disease. However there are some drugs which can shorten outbreaks making them less severe, like acyclovir, valacyclovir and famciclovir. Here is Allison Freeman, an avid natural researcher of homeopathic as well as medical home remedies and herbal medicine, who got her HSV2 infection from her husband just before they got divorced from each other three years ago as he was involved in an extramarital affair.
She already had traces of HSV1, so now she had gotten doubly infected with the agony of a bitter divorce that she had to undergo along.
She technically knew there was no cure for the ailment, so she couldn’t even make new relationships to acquire an emotional balance in her life. She took up a course in homeopathy and was given an assignment named “Influential Doctors in Alternative Systems of Medicine” to complete. She decided to write about a two-time Nobel Prize-winning doctor who had discovered that viruses could only thrive in low oxygenated bodies. The more the oxygen level in the body, the more the immunity against the attack of viruses and bacteria! As she came across this information from medical home remedies, there were bells starting ringing in her ears; for the very obvious reason that she got an insight into eliminating her genital herpes symptoms only if somehow she could raise the oxygen level in her body cells.



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