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Doctors for Education is a non-profit organization whose goal is to bring health and wellness education to your community. We are a group of multi-disciplinary healthcare professionals who donate our time and resources toward raising the awareness of beneficial practices that increase productivity, improve health and stimulate learning.
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Doctors for Education is a group of multi-disciplinary healthcare professionals who are committed to provide health education to communities throughout Canada. You’ll have the cutest nails on the block, while handing out all that candy tonight!!
Multiple reasons explain why the vast majority of medically trained physicians support vaccinations. Both pharmaceutical companies and government organizations support a misguided agenda in which vaccinations are promoted as a primary tool to prevent disease.
To summarize, physicians exist in a world where vaccinations are considered the primary weapon for disease prevention.
When viewing an actual curriculum entitled TIME (Teaching Immunization for Medical Education) used in the training of physicians in medical school, the focus appears to be on review of the childhood vaccination schedule, methods to encourage parental compliance and advocacy of the safety and effectiveness of vaccines to prevent disease. Historically, larger numbers of cases of vaccine-preventable diseases were greatly reduced by vaccination.
Given a child who is behind schedule, explain the principles of accelerated and catch-up vaccination, and determine needed vaccinations for current and subsequent visits.
Explain the rationale for simultaneous vaccine administration and the potential consequences of non-simultaneous administration. Given a patient scenario, identify valid contraindications and precautions to vaccination without missing vaccination opportunities that are appropriate. Explain general vaccine safety and adverse event information, including the Vaccine Injury Compensation Program (VICP), the Vaccine Adverse Event Reporting System (VAERS), and use of the Vaccine Information Statements (VISs). Suggest three procedures that a physician can implement in a practice or clinic to improve childhood vaccination rates.
Conducting problem solving and goal setting activities, following an evaluation of the practice’s current vaccination rates. Having office staff assess vaccination status at patient registration or during vital signs.
This focus in medical school on vaccination schedules and compliance has been validated by physicians who have shared their medical school training experience. Physicians are taught in medical school that vaccinations are responsible for eliminating disease. Pharmaceutical companies donate billions of dollars to medical schools, and with their funding comes great influence on the curriculum for medical students. Government funding is even greater for many medical schools, which means that government institutions such as the CDC also wield great influence on medical school curriculum.
NPR did a survey which found that between 2 and 16 percent of medical schools’ annual budgets are derived from the pharmaceutical industry. The Centers for Disease Control has a national program called AFIX, standing for Assessment, Feedback Incentive and eXchange, which aims to increase vaccination rates. Rewards for physicians who improve their vaccination rates include publication of successes in newsletters and paid immunization conference registration for office staff. However, it is also clear that the American Academy of Pediatrics is highly funded by major pharmaceutical companies, including Pfizer, Sanofi Pasteur, Merck, Meda Pharmaceutical and Astra Zeneca. Physicians can face negative consequences if they fail to comply with recommended vaccine schedules on their patients. Documented life-threatening illnesses and death result from vaccines, challenging vaccine safety. Doctors live in a world where vaccinations are a key part of their medical training curriculum, with the emphasis on how to achieve high vaccination rates.
Physicians face negative consequences if they question vaccination rates and don’t push vaccines on their patients. Pharmaceutical companies, which make vaccines, are a primary funder for medical school education and physician professional organizations.
Michelle Goldstein is a mental health therapist who is passionate about holistic health, natural healing, nutrient-dense foods and the politics that impact them.
Medical industry kills around 200,000 patients yearly – wonder how many of those are vaccination victims. No, they did not spent their lives understanding medicine and science; quite to the contrary, they spent over 12 years being indoctrinated into a irrational system found only down the medical industry rabbit hole.
Contribution of thymidine kinase (TK) mutations to acyclovir (ACV) resistance were evaluated in herpes simplex type 1 recombinant viruses generated using a set of overlapping cosmids and plasmids. Figure 1: Schematic representation of viral cosmids and plasmids used to generate HSV-1 recombinants into Vero cells. Figure 2: Replication kinetics of several HSV-1 mutants and the WT virus in a single-step growth experiment. We went up there last Monday to get ready for the Sprott Vancouver Natural Resource Symposium, which kicked off Tuesday evening and went through Friday. After an initial cocktail reception on Tuesday evening, the show really got going Wednesday morning. Attendees also heard from Adrian Day and Kim Iskyan, followed by renowned but reclusive billionaire Robert Friedland. Friedland led the discovery of Voisey Bay, one of the largest nickel deposits in the world, as well as the sale of Oyu Tolgoi, a massive copper complex in Mongolia. He is now the Chairman of Ivanhoe Mines Ltd., which is developing three world-class deposits in the DRC and South Africa.
He told the audience about the world’s problems with the supply of metals such as platinum and copper.
Other speakers on the first day included Brett Aitken of Stansberry Research, John-Mark Staude of Riverside Resources, Darin Wagner from Balmoral, Almaden’s Morgan Poliquin, and Miles Thompson of Reservoir Minerals. I didn’t get to listen to most of these speeches, so I’ll just have to listen to the recordings. It wasn’t hard to sense that many of the attendees saw the opportunity to get into natural resources now, when it feels like a bottom. The bear market may have culled investors, but those remaining seem sophisticated and wealthier than typical bull market investors.
The morning keynotes that followed came from Frank Trotter of Everbank, Byron King of Agora Financial, Louis James, a couple speakers from the Lundin Group, Ivan Bebek of Cayden Resources and Jeff Clark of Casey Research. Andy Schectman, who started the precious metals coin dealer Miles Franklin alongside his father, struck a chord:  Is gold being knocked down on purpose? Doug categorically denied the notion that precious metals were being controlled in his Friday talk.
Casey Research once again wrapped up the day with a special panel, featuring their “NexTen” – people who are set to transform the mining industry. He said the most important thing to do now is to understand how to profit from ‘NIRP,’ and avoid the stunning losses that will occur when the ‘NIRP’ world implodes. We ended the whole show with a “farewell panel” that featured Rick Rule, Adrian Day, Keith Schaefer, and Byron King. Along with some hardball questions ranging from the panelists’ biggest mistakes to Russia, the panelists were asked for their single top pick. Finally, Adrian sparked the question everyone had been waiting for: Will the Sprott conference return? Raucous applause from the audience was the response – a great note on which to end our inaugural event. To hear all the impromptu remarks, the bombshells, and the speakers’ own picks, you can order the recordings straight to your inbox. The audio replay of the event is available for a fee from Agora Financial.


Advertising you may receive from speakers or their companies should not to be construed as originating from or connected in any way to any Sprott affiliated entity. This entry was posted in Gold News and tagged Eric Sprott, Henry Bonner, Rick Rule, Sprott's Thoughts. What I do find interesting, is that Doug Casey says no manipulation, yet Ed Steer (who posts a daily report at the casey research site) would appear to think and speak otherwise.
THE ANALYSIS AND DISCUSSION PROVIDED ON SILVERDOCTORS IS FOR YOUR EDUCATION AND ENTERTAINMENT ONLY, IT IS NOT RECOMMENDED FOR TRADING PURPOSES. We seek to educate business organizations, schools and various community groups on the importance of natural health remedies and a balanced lifestyle in achieving peak potential. As you apply the second coat of polish (one nail at a time) take your q-tip and dab it into the glitter. Tap the q-tip over the tips of your nails, creating a more dense look at the tips and fading into your nail bed. Physicians receive the majority of their training during medical school, which is heavily influenced by pharmaceutical companies and government institutions such as the Centers for Disease Control and Prevention (CDC).
Subsequently, vaccination rates should be monitored with ongoing feedback to providers about vaccination rates.
Pharmaceutical companies are the makers of vaccinations, so they profit largely by teaching medical students, future physicians, the importance of vaccinations for health. As one example, the University of Oklahoma Health Science Center, a medium-sized medical school with 585 students, obtained 13.5 percent of its budget from pharmaceutical companies in 2003.
The program began as a pilot program in Georgia in 1986, and then was adopted across the country in both public and private physician offices.
Sponsors for rewards may include local businesses, coalitions, professional organizations, managed care or HMOs and vaccine manufacturers. As one example, the American Academy of Pediatrics holds a strong stance for total vaccine compliance. These companies profit from the sales of vaccinations and pharmaceutical drugs, which are recommended by pediatricians. Doctors risk being dropped from insurance companies, losing hospital privileges and becoming ostracized from their peers.
Outbreaks of diseases continue to occur in those vaccinated, raising the question of vaccine effectiveness.
Vaccine safety and effectiveness in eliminating diseases is emphasized, with no balanced teaching of vaccine dangers and questionable vaccine effectiveness. All professional physician organizations support strong vaccine policies, which adds additional pressure for physicians to vaccinate their patients.
Unfortunately, because of the large influence of pharmaceutical companies, government agencies and their training, most doctors are pressured to endorse a failed vaccine policy which has proven to be more dangerous than beneficial to their patients. Alterations in both conserved and non-conserved regions of the TK gene were shown to confer high levels of resistance to ACV.Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) infections are associated with serious complications in immunocompromised hosts.
On the day of infection, confluent Vero cells in 12-well plates were infected with recombinant viruses at a MOI of 2. Even coming from San Diego, there just isn’t anything that quite matches Vancouver in the summertime. Rick Rule was the opening speaker, and he delivered an entertaining talk on the cyclicality of the resource market, followed later by an introduction of the different exhibitors. Besides being the metal of choice for electrical grids, it is also underused in medical settings.
They had gathered a select group of “hall of famers” in the mining industry: Ross Beatty, David Lowell, Ron Netolitzky, Ron Parratt, Mark O’Dea, Bob Quartermain, Ron Thiessen, and Andy Wallace. The powers that be “don’t care” about gold, he said, “they don’t consider it money.” And besides, prices are manipulated anyway by market participants, as that is how markets work, but not suppressed by governments and bank cartels. Friedland has likely made more money for investors than nearly anyone else in the industry. Global Investors Inc., Keith Schaefer, author of Oil and Gas Investments Bulletin, and, finally a special video address from Bill Bonner, Founder of Agora Inc. THE DOC IS NOT AN INVESTMENT ADVISER AND INFORMATION OBTAINED HERE SHOULD NOT BE TAKEN FOR PROFESSIONAL INVESTMENT ADVICE. If you have a little extra time while painting your nails, you have to try glazing your nails with loose glitter! Doctors are pressured to vaccinate or face negative professional and financial consequences.
It takes great courage, curiosity and independence for physicians to think outside of the box and do their own research on vaccines. Since these diseases are contagious, they can return if immunization rates drop, as has happened in other developed countries when immunization rates dropped (see Table 2). They are told about the death and misery that resulted from these diseases, which vaccines are credited for eliminating.
The school received grants from drug giants AstraZeneca, Merck, Novartis, Pharmacia and Upjohn, totaling $13.8 million.
Physicians are tracked for their vaccination rates and offered “prizes” and rewards for high vaccination rates.
Their organization’s home page is inundated with information on vaccines and their importance, including propaganda reminding physicians of the terrible diseases that vaccines are supposedly responsible for eliminating.
To explore further ten reasons NOT to vaccinate, see the article Ten Reasons Not to Vaccinate. All of her published articles to date can be found at her health website, Holistic Health to Go. Prolonged antiviral treatment is often required for the clinical management of these patients, which could lead to the emergence of drug-resistant viruses [222, 230].
Extracellular viruses were collected at different times post-infection (up to 120 h) and titrated onto Vero cells. The mines in South Africa that produce it are simply getting too deep to send humans down to collect the metals.
Copper is actually better at killing off germs than stainless steel, and should be increasingly used for doorknobs, clinical tools, and hospital beds, he explained. His speech title, “Mega Wealth through Mega Discoveries” is probably the best description of his professional career. The discussion was honest and to-the-point, with Louis James of Casey Research as moderator. That and the unbearably loud construction noise outside my rental apartment at around 6:00 AM!
The objective of this final talk was to give attendees a taste of what he’s actually looking at now, and could be of interest to our group of investors. THE COMMENTARY ON SILVERDOCTORS REFLECTS THE OPINIONS OF THE DOC AND OTHER CONTRIBUTING AUTHORS. For those who dare to think outside of the box, they can face negative professional and financial consequences. The immune system is capable of responding to 100,000 vaccines at one time, according to the abstract by Dr. Contrary views, facts, reality and positions on disease elimination and vaccine dangers are not emphasized. More than half of their budget came from the National Institute of Health and other federal agencies, totaling $58.8 million. For hospital-employed physicians, losing financial bonuses can be a consequence for not vaccinating. Acyclovir (ACV), which has been the standard treatment for HSV infections, must be first phosphorylated by the viral thymidine kinase (TK) and then by cellular kinases before inhibiting the virus-encoded DNA polymerase (DNA pol) (reviewed in [442]). Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids.


Platinum is principally used for purifying motor exhaust, so it’s a hot commodity in the world’s growing mega-cities, where air pollution is taking a serious toll on their inhabitants. Media is the sponsor of this symposium and provides a forum for speakers we believe have useful and reliable information for you. YOUR OWN DUE DILIGENCE IS RECOMMENDED BEFORE BUYING OR SELLING ANY INVESTMENTS, SECURITIES, OR PRECIOUS METALS.
In clinic, HSV resistance to ACV is most commonly due to mutations (substitutions, deletions or additions) in the viral TK gene [233].
In the ‘NIRP’ world, which stands for “negative interest rate policy,” you get to borrow money for less than the real cost of capital. WE DO NOT SHARE IN YOUR PROFITS, AND THUS WILL NOT TAKE RESPONSIBILITY FOR YOUR LOSSES AS WELL.
Single base substitutions in the viral DNA pol gene have been more rarely reported in ACV-resistant clinical HSV isolates, with or without additional TK mutations [230, 286]. In such a world, money doesn’t matter and anything is possible – because the value of money is less than nothing.
Because of the presence of multiple mutations within these two genes including several ones associated with viral polymorphism [230, 234, 249, 261, 446, 447], it has been difficult so far to analyze the contribution of each specific HSV mutation with regard to the ACV resistance phenotype. We recently reported the generation and characterization of HSV-1 DNA pol mutants [443] using a set of four overlapping cosmids and three plasmids based on the original work of Cunningham et al. Herein, we report a modification of this cosmid-based recombination system to evaluate the impact of HSV-1 TK mutations as well as double TK-DNA pol mutations on the ACV resistance phenotype.Vero cells were maintained in minimum essential medium supplemented with 10 % fetal calf serum. The HSV-1 recombinant strain 17 and all mutant viruses derived from this strain were propagated in Vero cells. The method used to generate HSV-1 recombinant viruses from overlapping cosmids (gift of Charles Cunningham, MRC Virology Unit, Glasgow, United Kingdom) as well as the plasmid used for site-directed mutagenesis of the viral DNA pol gene have been described elsewhere [443]. Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues. Media and its agents and affiliates is of a general nature and not tailored to your specific situation nor should any statement be considered as such.  You should always consult an investment professional for advice regarding your specific situation. Specific mutations in the TK gene (located between nt 186 to nt 1007 of the viral gene) were introduced into plasmid pYS-1 using the Quickchange site-directed mutagenesis kit (Stratagene, La jolla, CA).
The correct nucleotide sequence of each mutated TK gene was verified by sequence analysis and compared to that of strain 17.
Briefly, digested cosmids (n = 4) and plasmids (n = 3) were transfected using Lipofectamine 2000 (Invitrogen, Burlington, ON, Canada) into Vero cells seeded in 12-well plates. The TK and DNA pol sequences of each recombinant virus were again verified by DNA sequencing.
Acyclovir susceptibility of each recombinant virus was determined by the use of a plaque reduction assay (PRA) [449]. A two-fold difference in IC50 values between the recombinant wild-type (WT) and mutant viruses was considered significant [443]. Evidence that the "active centre" of the herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide. All experiments were done in duplicate using two independently-generated viruses for each mutation of interest. Replication kinetics of each recombinant mutant virus (tested in duplicate at a multiplicity of infection (MOI) of 2) were compared to that of the recombinant WT virus by titrating extracellular viruses collected at specific times post-infection (up to 120 h) onto Vero cells [443].Eight recombinant HSV-1 viruses (WT, TK-deleted, 4 TK mutants, 1 DNA pol mutant and 1 dual TK-DNA pol mutant), selected on the basis of their report in previous clinical or laboratory studies, were successfully generated in this study. All recombinant mutants were resistant to ACV with the single DNA pol mutant D907V being the less resistant (4-fold change in IC50 compared to WT) and the double TK (deleted C467 with truncated protein)-DNA pol (D907V) mutant being the most resistant (62-fold change in IC50).
2, the replication kinetics of the mutants were relatively similar to that of the WT virus up to 120 h post-infection. Our results obtained with recombinant viruses, which allows mutational studies in a homogeneous background, revealed that several mutations in conserved but also in non-conserved regions of the TK gene are associated with high levels of ACV resistance.
The mutation K62N, located in the ATP-binding site of the TK, conferred the highest level of resistance to ACV with the exception of the TK-deleted virus and the dual TK-DNA pol mutant. The importance of the lysine at position 62 has been previously demonstrated in a site-directed mutagenesis study [450].
This mutation, also described in an ACV-resistant varicella-zoster virus isolate [451], has been associated with a TK-low producer phenotype. The mutation C336Y, implicated in the conformation of the TK protein, also resulted in a phenotype highly resistant to ACV.
The latter mutation was first described in laboratory-derived ACV-resistant mutants [247, 253] but also in a TK-altered clinical HSV-2 isolate [287].
Of interest, the mutation P131S, located in a non-conserved region of the TK gene, also conferred an ACV-resistant phenotype. This mutation has been previously described in a laboratory-derived mutant passed in the presence of ACV [452].
Since this ACV-resistant mutant contained both the P131S TK mutation as well as a DNA pol mutation (A719V), our study was able to confirm the role of the former mutation in conferring resistance to ACV. A single TK mutation (deletion of a C at position 467 leading to a truncated protein) induced high level of ACV resistance whereas the single DNA pol mutation D907V, within a non-conserved gene region, induced low level of resistance to ACV. The recombinant virus containing the two previous mutations had the highest ACV IC50 value among all recombinant viruses confirming the synergistic effect of dual TK-DNA pol mutations. The simultaneous presence of these two mutations was reported in a HSV-2 isolate from a patient with AIDS in whom ACV and foscarnet therapy sequentially failed [230]. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome. Our study unequivocally shows that the deletion of a C at position 467 in a homopolymer run, which introduces a stop codon 25 amino acids downstream, was mainly responsible for the ACV resistance phenotype of this isolate. Finally, as expected, the TK-deleted recombinant virus was highly resistant to ACV although not much more than single TK substitutions such as K62N and C336Y.Alterations in the TK are most frequently seen in clinic, probably because this protein is not essential for viral replication in most tissues and cultured cells [233, 234].
Indeed, the replication kinetics of all tested recombinant viruses including the TK-deleted virus were similar to that of the WT virus. In addition, mutation D907V, located in a non-conserved region of the DNA pol gene, did not affect viral replication in contrast to other previously-reported DNA pol mutations located within conserved gene regions [443]. In conclusion, we have developed a system that now allows rapid assessment of any mutations found in both viral genes associated with ACV resistance. Such methodology could serve to develop virtual drug phenotypes for HSV with systematic evaluation of viral mutations found in clinical specimens.
Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients. An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase. Polymorphisms of thymidine kinase gene in herpes simplex virus type 1: Analysis of clinical isolates from herpetic keratitis patients and laboratory strains. Role of genotypic analysis of the thymidine kinase gene of herpes simplex virus for determination of neurovirulence and resistance to acyclovir. Site-directed mutagenesis of a nucleotide-binding domain in HSV-1 thymidine kinase: effects on catalytic activity.
Genetic characterization of thymidine kinase from acyclovir-resistant and susceptible herpes simplex virus type 1 isolated from bone marrow transplant recipients. Characterization of the DNA polymerase and thymidine kinase genes of herpes simplex virus isolates from AIDS patients in whom acyclovir and foscarnet therapy sequentially failed. Differential mutation patterns in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 clones passaged in the presence of acyclovir or penciclovir.
Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS.



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