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Shingles normally bothers only one side of the body with painful rashes or pus filled blisters. Experts believe that shingles are caused due to weakened immune system after certain infections or the person grows old.
Anyone with lowered immunity like children, old age people, those affected with cancer, AIDS and other immune related disorders are prone to get shingles if they already had chickenpox in their life.
Your doctor can easily identify shingles from the symptoms of intense pain and blisters with rashes on one side of the body. Chickenpox vaccine and Shingles vaccine (varicella zoster virus) can be taken to prevent this painful disease.
Getting vaccinated can be easy, and the ZOSTAVAXA® II vaccine is available in most clinics, doctorsa€™ offices or pharmacies. Find FAQs and information about adult vaccination to help you understand, manage and prepare for shingles. ZOSTAVAXA® II is given as a single-dose injection and works by boosting your immune system to help protect you from shingles. Herpes zoster (HZ) is a painful and potentially serious condition that can result in a significant burden of illness, mostly related to postherpetic neuralgia (PHN). The HZ vaccine is recommended for persons aged 60 years of age and older, and may also be used in adults 50 years of age or older. Download the ZOSTAVAXA® II brochure to learn more about shingles, the shingles vaccine and questions to ask your healthcare professional.
ZOSTAVAXA® II is the only vaccine available to help prevent shingles in individuals 50 years of age or older. ZOSTAVAXA® II does not protect everyone, so some people who get the vaccine may still get shingles. Persons using assistive technology might not be able to fully access information in this file. The triggers for reactivation of VZV have not been identified and probably involve multiple factors.
Zoster rash is typically unilateral and does not cross the mid-line, erupting in one or two adjacent dermatomes. The frequency of zoster occurrence in different dermatomes has been evaluated in certain studies.


Regardless of definition, the pain of PHN can last for weeks or months and occasionally persists for many years.
The prognosis for these conditions is good, although encephalomyelitis can be life threatening. The risk for neurologic zoster complications is generally increased in immunocompromised persons. VZV can be transmitted from zoster lesions to cause primary varicella in susceptible persons. Finally, one study indicated that dietary micronutrient intake was protective against zoster.
Despite these limitations, certain analyses of zoster incidence in the United States have been conducted.
Zoster vaccination is not recommended for persons of any age who have received varicella vaccine. Persons with clinical or laboratory evidence of other unspecified cellular immunodeficiency. Persons receiving recombinant human immune mediators and immune modulators, especially the antitumor necrosis factor agents adalimumab, infliximab, and etanercept. It is the one that causes chickenpox in humans and the virus remains dormant in the nerve tissues for years which will develop causing shingles later. The virus remains inactive in the body for long years which will become active when the conditions are favorable. It would cause burning sensation on the affected part of the body and for some people there can be numbness or tingling feeling indicating nerve infection.
Pain is the first sign for this disease and for some there may not be any rash at all on the skin.
Anyone with chickenpox can develop shingles later in his life since the virus can remain dormant in the nervous tissue for years. This condition is described as postherpetic neuralgia where the damaged nerve will send pain signals to the brain.
It cannot be used to treat existing shingles or the pain associated with existing shingles.
For most people, the pain from shingles resolves as the rash heals, but for others, it can last for months or even years.


Up to 10% of people over 65 years of age will be admitted to hospital with an episode of HZ.
However, if you develop shingles despite being vaccinated, ZOSTAVAXA® II can help reduce the intensity and duration of pain. This report provides recommendations for use of zoster vaccine for prevention of zoster and its sequelae.
Zoster also can result in autonomic dysfunction, causing urinary retention and colon pseudo-obstruction.
A prospective cohort study indicated a nonsignificant association (p = 0.078) between zoster risk and negative life events.
In addition, no evidence existed of transmission of vaccine virus from vaccine recipients to contacts.
Approximately 1%--4% of zoster episodes result in hospitalization, with a mean duration of 4.8 days. Many of these cases cause debilitating pain, and when PHN develops, the pain can last for months or even years. This disease is marked by painful rashes on the body that produces blisters on one side of the body. There is no vaccine for preventing shingles but old age people can take a shot of zostavax for reducing the chance of getting shingles. It can cause moderate to severe itching and the pus inside the blisters will break open after some days.
In addition to the above, it can cause headache, fatigue, fever and body ache for some people.
The risk of spreading the disease is more during the period when the fluid from the blisters break open. Some people use lidocaine for numbing the affected area to prevent the nerve from sending pain signals to the brain.



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