Diabetes Mellitus is a group of metabolic diseases characterized by high blood glucose levels, disturbances of carbohydrate, fat and protein metabolism resulting from either insulin secretion and or insulin action. The International Diabetes Federation predicts that there will be 334 million diabetics by 2025. The classical symptoms of diabetes mellitus are Polydypsia, Polyphagia, Polyuria and unexplained weight loss.
By increased frequency of urination (Polyuria) the body tries to remove the dangerously elevated levels of glucose in the blood and excretes it through urine, hence diabetes mellitus commonly was referred to as sweet urine disease in the earlier times.
Increased appetite (Polyphagia) in a diabetic is a result of the body cells inability to take up nutrients and glucose (due to inefficient insulin secretion and or insulin action) and also because the unused glucose comes out of body through urine.
As the body needs energy and is unable to use glucose (due to inefficient insulin secretion and or insulin action), it converts fat into free fatty acids for energy leading to weight loss despite a normal appetite. Due to the high blood glucose levels, some of it is taken up by lens leading to a distorted blurred vision.
Recurrent skin infections is often seen in diabetics as the glucose provide a rich environment for the micro organisms to grow.
The feeling of fatigue is a common symptom as the cells are unable to use glucose to produce energy. Breath that smells sweet and like nail polish remover needs immediate medical attention as it is probably due to diabetes ketoacidosis which is a deadly complication. This may be accompanied by feelings of nausea, weakness, rapid heartbeats, abdominal pain and deep and rapid breaths. In hypoglycaemia (low blood sugar) the diabetic experiences weakness, fainting spells, rapid heartbeat, excessive sweating, trembling, irritability, hunger or suddenly drowsiness.
People with Type – I diabetes mellitus develop symptoms over a short period of time whereas type – II diabetes mellitus symptoms are often not as noticeable as in Type – I. Another form is the Gestational diabetes mellitus which occurs only in pregnancy and disappears after the birth of the child.

Fever can simply be viral but persistent fever may be an early sign of blood cancers like lymphoma or leukemia.
If you have lumps in your body then you might not want to lose any more time in visiting the doctor.
If you have a persistant sore or sores that don't seem to heal, you should get them checked out by a doctor right away. If you notice any kind of persisting change in your skin, you should immediately rush to doctor. Apart from all this points, if you notice any other significant changes in your body, visit a doctor as soon as possible, especially if the changes persist or get worse.
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In Type-I either the body have stopped making insulin or the amount of insulin produced is less whereas in Type –II there may be decreased or nil insulin levels and or the insulin levels may be normal but it is not being utilized by the body (Insulin resistance).
Symptoms of diabetes vary from person to person and are related to elevated blood glucose levels. Excessive thirst(Polydypsia)is due to dehydration resulting from excessive urination and sweating. This is a temporary change and the vision improves as the blood sugar level returns to normal. Slowly healing ulcers, sores, wounds cuts are due to decreased immunity and blood circulation to the wound. Diabetics are usually irritable and or depressed due to decreased glucose supply and nutrition to the brain.

One should be given a carbohydrate snack or a glucose drink quickly to avoid more serious complications. If you experience persistent fever, you should see a doctor, even if it's not cancer, it's still an alarming sign.
This is a tricky one because a lot of people feel fatigue for completely different reasons. But if you find yourself losing weight with no change in your habits, this is an unexplained weight loss and it can be associated with several cancers including cancers of the pancreas and stomach.
Sores inside the mouth can be signs of an oral cancer, and sores on the skin can be a sign of skin cancer. But persistent headaches can be an early sign of brain cancer and back pain can be a sign of rectal or ovarian cancer.
But if you start suddenly feeling tired all the time you should check with your doctor to make sure it isn't something serious. Coughing up blood can mean lung cancer, blood in the stool can mean colon or rectal cancer, blood in urine can mean bladder cancer, persistant vaginal bleeding can mean cervical cancer, and blood discharge from the nipple can mean breast cancer.
Don't freak out if you find lumps on your arms, legs, or other parts of the body though, they might just be harmless sebaceous cysts.

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