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Herpes infection or Herpes simplex is a disease which is viral caused by herpes simplex virus type 1 or HSV-1 and type 2 or HSV-2.
These are other types of herpes which are all caused by herpes simplex virus: Herpes gladiatorum, herpes whitlow, ocular herpes or keratitis, encephalitis cerebral herpes infection, neonatal herpes, Mollaret’s meningitis.
Herpes simplex virus type 1 causes face, eye, mouth, throat, and central nervous system infections.
Through clinical examinations, orofacial herpes are identified to persons who have no history with such lesions or contact with persons having HSV type-1 infection.
Genital herpes in persons infected with HSV type-2 virus are more difficult to diagnose because there are other conditions that resemble genital herpes such as lichen planus, fungal infection, urethritis and atopic dermatitis. Herpes simplex virus can’t be eradicated in the body and there is still no discovered method for it. Persons with weak and suppressed immune system like in newborns, AIDS, and transplant patients are more prone to acquiring this infection.


The distribution and appearance of sores appear as round, multiple, superficial oral ulcers with acute gingivitis. Laboratory tests are done to diagnose genital herpes which include virus culture, virus detection through direct fluorescent antibody studies, polymerase chain reaction to identify DNA virus, and skin biopsy. However, there are antiviral medications that can lessen the outbreak severity, duration and frequency of infection. Acyclovir is the first discovered drug for herpes simplex virus and is now available in generic forms. After a primary infection, the nerves are entered by the virus at the primary infection site, migrate to the neuron’s cell body and become hidden in the ganglion.
Sometimes, orofacial herpes lesions are mistaken as impetigo, a bacterial infection, if lesions are not seen inside the mouth. These laboratory tests are specific when it comes to diagnosing but because of high cost, it constrains the infected persons from submitting themselves to test.


As a result, antibodies are produced by the body for the particular herpes simplex virus type to prevent further infection to a different site. In HSV type-1 infected persons, additional infection is infected through seroconversion or development of specific antibodies in the blood serum. If a person is infected with HSV type-2, the symptoms are minimal because of the help of seroconversion.



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