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HERPES BLOOD TESTSFACT SHEET AND QUICK REFERENCE GUIDEIf there is a visible symptom present, the standard procedure is to perform a viral culture. Put simply, blood tests can show that you are positive for the antibodies, but they cannot show that you are negative for the virus itself. Antibodies are substances produced by your immune system to fight off infections or antigens (such as herpes). This method of testing has the advantage that it can be done even when a person has no symptoms, so it is a very effective way to detect an established herpes presence. A number of similar tests are produced for research purposes and commercial products are gradually becoming more available. The HSV Western Blot detects HSV-1 and HSV-2 proteins which have been separated by size so that type-specific antibody profiles can be recognized with a specificity of >99% .

Centre of Disease Control guidelines stipulate that only type-specific serologies based on glycoprotein G be used. It is regarded as more precise than the (ELISA) and is sometimes used to check the validity of ELISA tests. If the herpes antibodies are found in the blood, it means that your body was exposed to the herpes simplex virus at some point in your life and created antibodies in response.
Blood tests do not require swabbing a lesion, so they can be done long after symptoms have faded. This method may be used to distinguish maternal from infant antibody profiles and to distinguish serum and cerebrospinal fluid profiles of HSV antibodies. Even commercial, FDA-cleared tests like the HerpeSelect ELISA from Focus Diagnostics-Quest may have false positive results, especially in samples with low positive readings. It is now recommended that clinicians avoid serology tests unless they are type-specific tests.

This test has been exhaustively validated in studies of well-characterized patient populations. It is the current gold standard HSV serology and provides a highly accurate confirmatory test for positive results by ELISA. Conclusive results is currently several fda-approved, gg-based blood test gynocologist appointment weeks.

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