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admin 09.11.2013

Put simply, blood tests can show that you are positive for the antibodies, but they cannot show that you are negative for the virus itself. Antibodies are substances produced by your immune system to fight off infections or antigens (such as herpes). This method of testing has the advantage that it can be done even when a person has no symptoms, so it is a very effective way to detect an established herpes presence.
A number of similar tests are produced for research purposes and commercial products are gradually becoming more available.
The HSV Western Blot detects HSV-1 and HSV-2 proteins which have been separated by size so that type-specific antibody profiles can be recognized with a specificity of >99% .
Centre of Disease Control guidelines stipulate that only type-specific serologies based on glycoprotein G be used. Based on the test results an active disease, immune status or even re-infection can be identified and a differential diagnosis can be created.
It is regarded as more precise than the (ELISA) and is sometimes used to check the validity of ELISA tests. If the herpes antibodies are found in the blood, it means that your body was exposed to the herpes simplex virus at some point in your life and created antibodies in response. Blood tests do not require swabbing a lesion, so they can be done long after symptoms have faded. This method may be used to distinguish maternal from infant antibody profiles and to distinguish serum and cerebrospinal fluid profiles of HSV antibodies. Even commercial, FDA-cleared tests like the HerpeSelect ELISA from Focus Diagnostics-Quest may have false positive results, especially in samples with low positive readings. HerpeSelect is able to deliver accurate type-specific results for HSV-1 or HSV-2 IgG antibody testing. Since herpes infections tend to be recurrent, the antibody response will be maintained, but there is no specific number that would indicate whether it is a more recent or distant infection.


It is now recommended that clinicians avoid serology tests unless they are type-specific tests.
This test has been exhaustively validated in studies of well-characterized patient populations. If the equivocal result becomes positive, you can say that there has been a recent HSV1 infection. I asked for the actual scorings and they said they didn’t have those (just Negative and Equivocal) but that they would like me to do another blood test in a couple weeks which I plan to do.
It is the current gold standard HSV serology and provides a highly accurate confirmatory test for positive results by ELISA.
I just wanted to mention that the equivocal results taken in February and March both were positive HSV III IGM. You should have had an actual result listed on the test which would then be measured against this scale.
According to this, wouldn’t that mean that, were the test equivocal because I DO have it and the antibodies aren’t strong enough, it came from the most recent ex, who I last saw about 2 and a half months ago? 10, then you would be in the equivocal range which is sort of a no mans land that doesn’t really tell you if you are truely positive or not and you would go back and get tested again. It seems as though, were I to have the virus, it would have shown up as positive if it were from anyone in my past.
4) A positive IgG to herpes does not tell you when you acquired the infection, just that at some point you did. According to this doctor, there’s a 50 chance that an equivocal HSV2 result is actually a negative. When the results come back equivocal (four months out from last contact) , what is the ideal amount of time to wait before retesting? Infections with HSV types 1 and 2 can differ significantly in their clinical manifestations and severity.


Your doctor may also use words like equivocal or inconclusive to describe this result (see below). In addition, the results of HSV type-specific IgG testing is sometimes used during pregnancy to identify risks of congenital HSV disease and allow for focused counseling prior to delivery.
So now i am left with a real dilema, I actually do love this girl, she is the most amazing lady i have ever met, and i was planning on spending the rest of my life with her, however now with this bomb shell, I dont know what to do?
1 or 2 indicates previous exposure, and does not necessarily indicate that HSV is the causative agent of an acute illness. If you get a positive result from a viral culture then you can be very confident (95) that you have genital herpes.
Remember that direct testing means testing for the presence of the herpes virus whereas indirect testing checks for the presence of blood antibodies. It might mean your friend is screwed but that doesn’t make it wrong, sometimes people just get dealt a bad hand.
In fact, the vast majority of occurrences of neonatal herpes result from a baby being kissed by someone who has just contracted coldsores. Personally, I don’t think her test results will mean much, or allow me to resolve this, even if they do come back positive. I am concern about my HSV-1 IgM result, is it mean that i got oral herpes or is it only a false positive? These are very technical questions and you can google all about the process as there is no time to explain it here. 10 IV or greater Positive-IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection.



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  • IP, 09.11.2013 at 11:49:19
    The place HSV typically hides.
  • Joker, 09.11.2013 at 13:50:23
    Way of oral genital contact shut contact with anyone.
  • Alla, 09.11.2013 at 23:12:53
    Commercially accessible vaccine that is protective towards genital now, if you happen.
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    Factor you can do after train ganglia alongside the.