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admin 24.02.2016

You’ve most likely heard of medical reports touting the effectiveness of a diet plan, a new drug, a supplement, or medical procedure.
Strikingly, the odds are that the studies that influenced your decision, and possibly the decision of your doctor, were wrong. We are bombarded by medical research studies that don’t stand the test of time and potentially cause serious negative health outcomes. Ioannidis’ research model indicated that up to 80 percent of non-randomized research studies (the most common kind of study) are wrong, along with twenty-five percent of randomized trials (the supposed gold standard of research).
There are serious deficiencies in medical research that have an onerous impact on our well-being. Research Bias – Ioannidis defines bias as “the combination of various design, data, analysis, and presentation factors that tend to produce research findings when they should not be produced.” Many researchers enter their study with a specific finding in mind and, not surprisingly, they find it. Bias can happen in numerous ways, such as how the research is designed, how the samples are selected, and how subjects are pressured, or though errors in data collection and measurement or publication bias. Publication Bias – various industries, governments, and regulatory agencies may severely distort the truth by omission. An example of this occurred with nearly 100,000 people dying from taking “safe” prescription anti-arrhythmic drugs in the 1980s. This leaves us and our doctors in the dark about the efficacy and safety of drugs and medical procedures. Conflicts of Interest – many studies, especially drug studies, “…have the added corruptive force of financial conflict of interest.” The more embedded the financial and other interests in the outcome of a study, the more likely the findings are going to be false. Research findings can be distorted by: small sample size, poor choice of methodology, and erroneous statistical analysis, all of which are widespread in medical research. Given the distorted, corrupt and unreliable state of much of medical research how can we know what to do?
In his book Wrong, David Freedman lists some practical measures we can take to evaluate the reliability of medical research. Vic Bishop – Plastic fishing, started by company Plastic Whale, is an innovative approach to cleaning up the waterways of Amsterdam. Julian Spalding – What the caterpillar calls the end of the world the master calls a butterfly. Christina Sarich – There really is no better way to create a nation of obedient slaves than to lobotomize them from above. The summer Medical Student Research Program is a competitive mentored research program provided to medical students. After a project has been selected, the student should discuss the proposed research with the faculty member. Does the project relate to research on (a) heart, lung or blood, (b) diabetes, metabolism or digestive or kidney dieseases, (c) eye health or disease?
Does the project represent hypothesis-driven science?  Is there a clearly stated hypothesis and is there a test of the hypothesis?


Is there evidence that the student was involved in writing the proposal?  We realize that most of the proposals reflect projects generated by the ongoing studies in the mentors' laboratories, but we wish to see some evidence that the proposal reflects thought and effort on the part of the student and is not simply 'lifted' from a pre-existing grant. Does the project offer a learning experience for the student?  We do not want the student to be considered a 'pair of hands' doing a limited number of repetitive tasks, but want them to be exposed to different techniques and have the opportunity to generate experimental protocols. Is it feasible to accomplish, or at least initiate, a body of work in the allotted time frame?
This NIH-funded program currently funds 38-40 students from the University of Utah and 2-3 students from each of our partnering institutions, the Univeristy of Puerto Rico (URM) and the University of Nevada. People who take high doses of popular cholesterol lowering drugs called statins may be more likely to develop kidney problems. Canadian researchers analyzed health records of more than two million people ages 40 and older. Those who took higher doses of statins were 34 percent more likely to be hospitalized for acute kidney injury during the first 120 days of treatment compared with people who were taking lower doses. Other studies have shown a link between statin treatment and protein in the urine, which is a hallmark of kidney disease. Providence has positioned itself as a regional leader in clinical research through creation and support of Providence Medical Research Center in Spokane, Washington. Eastern Washington and Northern Idaho residents have access to latest advances in medical research, via Providence-affiliated clinicians and physician investigators, in disease specialties including heart and vascular diseases, kidney disease, diabetes, high blood pressure, nutrition, bowel disease, cancer and more.
Our work supports and advances the Mission of Providence by advancing knowledge essential to improving care for all - especially the poor and the vulnerable. Without medical research, there would be no antibiotics to treat infection, no insulin to manage diabetes, and no way to successfully transplant a kidney.
All research protocols conducted at Providence Medical Research Center in Spokane have oversight by the Institutional Review Board (IRB).
The current system of competitive grants to individual researchers is the best way to finance medical research. For nearly seven decades, federal agencies and many private funders have financed medical research through competitive grants to individual scientists who submit proposals for particular projects. But today’s competition for limited grant money encourages overly safe research, aimed more at producing positive results to bolster future proposals than at breaking new ground. Researchers are free to publish their findings, and scores of AMRF-based articles have appeared in journals including Science, Nature, Cell, Neuron and others. You may have even decided on a course of action based on these findings, only to find out later that they have been refuted by new studies. Our doctors use research to inform their medical decisions – decisions like what drug to prescribe, what surgery to elect, and what health strategy to adopt. Or more recently, when none of the negative studies of the anti-depressant reboxitene were published. Unless a study is a randomized control trial (RCT) it can not prove that one thing causes another, such as red meat causing heart disease.


Robert Oliva is a New York State licensed Master Social Worker, a traditional Naturopath, a certified Holistic Health Practitioner and a health and fitness writer.
I always believe that we should take responsibility when following advice or accepting treatment based on medical research. Students have the opportunity to work with basic science, clinical science, or health care research investigators.
The Spokane Medical Research Center coordinates a diverse spectrum of research studies, ranging from basic cellular science to new treatment studies, via federally-funded programs and industry-sponsored drug and device trials. These are just three of the countless examples of medical treatments made possible through research—and the list of new discoveries expands nearly every day. The current system discourages high-risk, high-payoff science and the publishing of crucial but less grant-worthy negative findings, slowing development of medical treatments.
Thomas Carmichael of the University of California, Los Angeles, the system pushes scientists into rivalry.
Streamlined application and approval processes cut the time and paperwork researchers must spend in search of grant money.
In fact, this article will show you how untrustworthy medical research is and what you must do to protect yourself and loved ones.
Ioannidis, currently a professor in disease prevention at Stanford University, published the most widely accessed article in the history of the Public Library of Science (PLoS) entitled Why Most Published Research Findings Are False. They are making crucial treatment decisions for depression, Alzheimer’s, type 2 Diabetes, cancer, obesity, etc. He is a member of the American Naturopathic Medical Association, the American Association of Drugless Practitioners and the National Association of Social Workers. Goals are to enhance students' research horizons and develop scientific presentation and writing skills.
They’re loath to share the creative ideas that no one else has and that could net them the next grant. Adelson Medical Research Foundation (AMRF) believes that collaboration and openness best fuel breakthrough science. Remember Vioxx, Hormone Replacement Therapy, anti-arrhythmia drugs, high carbohydrate diets?
Students are expected to present a poster at an annual symposium at Deer Valley, which their mentors attend and support their trainees. Travel funds may be available for a limited number of students who wish to present their research findings at national meetings. This can help in wading through the biased and damaging studies given the light of day in scientific journals and media.



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