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Pemphigoid gestationis is a rare pregnancy-associated autoimmune skin disease that is characterised by an itchy rash that develops into blisters.
Pemphigoid gestationis is an autoimmune blistering disease, which basically means that an individual's immune system starts reacting against his or her own tissue.
In pemphigoid gestationis the target is a protein known as BPAG2 (also called BP180), found within the basement membrane, which is the zone between the epidermis and the dermis (the top and middle layers of skin). The antibody attack results in inflammation and separation of the epidermis from the dermis allowing fluid to build up and create a blister. Most patients present with an intensely itchy hive-like rash during mid to late pregnancy (13 to 40 weeks gestation). Within days to weeks, the rash spreads to other parts of the body including the trunk, back, buttock, and arms. Diagnosis generally requires a skin biopsy, which shows typical features of subepidermal blistering, similar in microscopic appearance to bullous pemphigoid (BP) or epidermolysis bullosa acquisita (EBA). The primary aim of treatment is to relieve itching, prevent blister formation and treat secondary infections. In most cases, pemphigoid gestationis resolves spontaneously within days after delivery so treatment can be tapered off and stopped.
Low-carb snacks will ensure that you do not consume too many calories as that will lead to weight gain. Healthy Low Carb Snack Ideas Delicious and Crunchy Veggie Sticks with Exotic Spreads One of the most nutritious snacks that you could munch on are veggie sticks. These veggie sticks are loaded with vitamins, anti-oxidants and other vital nutrients that will keep your body healthy.


A blend of yoghurt with fresh mint leaves or cilantro leaves seasoned with salt and cumin powder makes for a delicious and healthy dip which goes well with most veggie sticks. Boiled Eggs Eggs are rich in many nutrients such as Vitamin A and omega-3 fatty acids which makes it a healthy snack which is also low-carb.
Low-Fat Yoghurt Topped with Fruits and Nuts For those looking to eat low-carb snacks, low fat yoghurt is a great option. There is a big debate about this term Superfoods between Doctors, Scientists and Dieticians.
BPAG2 is within the hemidesmosome, the cell component that sticks the epidermal keratinocyte cells to the dermis. Symptoms may lessen or spontaneously resolve towards the end of the pregnancy but this is short-lived, as 75-80% of women will experience a flare-up around delivery. Pemphigoid gestationis is confirmed by direct immunofluorescence staining of the biopsy to reveal antibodies. Topical corticosteroids are used in mild disease whilst oral corticosteroids are necessary in more extensive cases. Immunosuppressive medications such as azathioprine or ciclosporin may also be used successfully but their safety in pregnancy or during breast feeding must be carefully considered. Though eating small-sized frequent meals is recommended by dieticians for increased metabolism, munching on un-healthy snacks will certainly do you no good. Veggie sticks serve as ideal low-carb snacks since they are low in calories and contain no fats. Since we are looking to make low-carb and healthy snacks, it is recommended that you avoid high-calorie dips such as mayonnaise, ranch or blue-cheese dressing.


Low-fat yoghurt contains proteins, calcium, and vitamin A and is great for your digestive system.
It was previously known as herpes gestationis although it has no association with the herpes virus whatsoever. In most cases, symptoms resolve days later after giving birth, however in some, the disease remains active for months or years.
Minimum effective doses should be used to reduce the risk of side effects to both mother and fetus.
So the next-time you want to reach out to a bag of chips, think of these healthier yet delicious low-carb snacks to keep youself fit and healthy.
You can also get innovative and make varied egg-based snacks such as flavorful deviled eggs. You can easily turn yoghurt into a delicious snack by topping it with your favorite fruits.Nuts such as walnuts and almonds too can be added to make your snack rich in good fats such as omega-3 fatty acids. Commencement of menstrual periods, use of oral contraceptives or further pregnancies may cause flare-ups.
In some cases, circulating antibodies can be detected by a blood test (indirect immunofluorescence test).



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