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PATHOPHYSIOLOGY OF ORAL CAVITY Roman Benacka, MD, PhD Department of pathophysiology LF UPJS. Anaemias oral mucosa exhibit pallor decreased resistance to infection - glossitis, recurrent aphthae, candidal infections, and angular stomatitis glossitis, tongue is reddened, the papillae are atrophic (first sign of folate or vitamin B-12 deficiency anaemia) angular stomatitis caused by a candidal infection (iron deficiency anaemia) Langerhans histiocytosis (histiocytosis X) abnormal histiocytic and eosinophilic proliferation - most common form is the eosinophilic granuloma in young adults. AIDS and other immunodeficiencies Candidiasis repeated oral candidiasis is the first sign in 90% of patients with HIV. Endocrine diseases Diabetes mellitus may increase the prevalence, incidence, or severity of gingivitis and periodontitis. Minocycline - associated bluish gray hue of the alveolar mucosa pigmentation in a patient who had used the drug for several months to treat severe acne. Ingredients of candies and chewing gums cinnamon compounds, menthol, propolis (a strong sensitizer often used in the oral cavity because of its antiseptic properties) Local use of drugs antibiotics, anesthetics, antiseptics, and steroids, desinfectives e.g. Allergic contact stomatitis on the gingiva in a patient with a positive patch test result to nickel, palladium, and mercury.
Chemical burns result in tissue necrosis produced by a chemical agent used by the practitioner or the patient to relieve pain. Manifestations of contact stomatitis Lichen planus–like lesions May occur at the site of mucosal contact with amalgam restorations - lesions are typically localized. White-colored findings Lichen planus - chronic dermatosis which may affect both skin and mucosa.
As human beings we understand the importance of a healthy smile, however, many of us who have pets, often neglect their teeth.


One of the first signs that your dog may be having a problem with their teeth is their breath. Most common is pseudomembranous type - white plaques on the soft and hard palates, buccal mucosa (most commonly), and tongue that leave a reddened area when scraped.
The lesion takes the aspect of a whitish plaque which can be removed, leaving an erosive, painful surface The bitten mucosa - alteration of normal tissue - whitish multiple erosions, abrasions and slight sloughing of the most superficial layers of the mucosa. Sensitization to gold, palladium chloride, and copper sulfate Leukoplakia-like lesions Contact sensitization from nickel and other metals commonly localized in the medial part of the cheek.
Oral intercrossing white lines that give the appearance of a weave or net (arboriform).In some patients the lesions may disappear spontaneously Leukoplakia - whitish lesion which does not slough off when scraped, histologically presents as a spot, keratosis of wartlike.
Ulcerations are usually covered by a yellow-white exudate and may present with an erythematous halo. It affects the buccal mucosa, lips and tongue wherever they can be reached by the patient?s bite.
Bad teeth can cause Bacterial Endocarditis, which is an infection of the lining of the heart. Heerfordt syndrome - triade: parotid gland swelling, xerostomia, uveitis, and facial nerve palsy. Chemical burns are not frequent because the oral mucosa is resistant to heat and acid or alkaline compounds. Although contact allergy (especially to mercury) has often been implicated, the disorder most likely has a psychogenic basis.


Typically, this form of infection enters through the body in the mouth, while spreading to other portions of the body or bloodstream. If any of these symptoms are constantly present with your beloved pet, please seek you nearest veterinarian to ensure that your pet gets the proper treatment if needed. Prolonged contact with aspirin or vitamin C tablets, or contact with irritants used for dental care.
Amyloidosis is classified as primary, stemming from multiple myeloma or an idiopathic disease, or as secondary, stemming from a chronic or inflammatory disease process Symptoms: affects the skin, heart, tongue, and GI tract, while the secondary form, although more common, has no cutaneous manifestations. Until disproved, all perineal and ulcerations should be considered HSV in patients who are infected with HIV. Endocarditis is more common in middle and large sized dogs between the ages of four and six. Contact urticaria Swelling of the lips, the tongue, the buccal mucosa, and the gingiva develops suddenly with intense itching due to allergy to foods. Since pets do not show pain from their gums, there are a few  symptoms listed below that could possibly indicate your dog needs immediate attention.



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31.08.2015, author: admin


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