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We’ve evolved to be able to shrug off the weight of the atmosphere and our ability to hear actually requires it. Now, when you’re in a rapidly climbing aeroplane, air pressure in the cabin will decrease while the pressure in the inner ear remains constant. The Eustachian tube will typically open on its own whenever you swallow hard but when you have a upper respiratory, infection the tubes might not open at all on account of your swollen throat.
Some folks will attempt to simply overpower this swelling by holding their nose, closing their mouth, and blowing; forcing air from the lungs into the tubes and equalizing the pressure.
Instead, drop a couple of decongestants before you take off to reduce the amount of snot running into your throat. I flew to Sydney earlier this week whilst I was recovering from a cold (yes, I was conscious of infecting my fellow passengers with my germs. It's possible that the office building you were in cranked up their negative pressure a bit too much.
In the case of an office building its not the altitude that's the problem its the negative (relative to outside) pressure generated by the HVAC system. The pressure change from the HVAC system inside the building is usually much more than the change due to altitude for 16 floors. Your ears could have hurt more after the decongestants wore off because you simply clogged up again.
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Your congested ears refuse to pop and now you’re stuck on a cross-country flight, cruising at 30,000 feet of ear-splitting agony. Though only a fraction of the density of our oceans, the atmosphere behaves much the same way.
Each inner ear is equipped with a small channel that runs down to the side of your throat known as a Eustachian tube.
No open Eustachian tube means no pressure equalisation means a really uncomfortable flight.
Your ears should have popped and you are now free to enjoy the rest of your flight — at least until the baby in row 15 starts crying again.
Tall buildings do it for various reasons but one of them being that if there is positive pressure outside it becomes a lot harder to break a window.
Still, they make you cry when you cut them, so I think that’s a valid sign that they should stay away from my hamburgers.
Just as water pressure increases the deeper you go, air pressure increases the closer you get to sea level. This thin vibrating membrane acts as a barrier to liquids but allows atmospheric reverberations to pass through, however this requires that the air pressure on both sides of the eardrum be roughly equal. It’s designed specifically to facilitate air to escape from the inner ear into the throat, allowing you to equalise the atmospheric pressure on either side of the eardrum.
Conversely, if you were to go scuba diving, the increased pressure on the outer ear relative to the inner would cause the drum to bulge inward.

Not only is there the very real chance of blowing too hard and tearing the eardrum itself, you can very well also blow all that infected mucus that’s draining down your throat into the Eustachian tubes and give yourself a raging middle ear infection. She handed me earmuffs just before I left to get on the plane, I don't thing they would have protected my ears much at all. These tubes are attached to the tensor veli palatini muscles in your soft palate and are activated automatically whenever you yawn or swallow.
In both cases, your auditory capacity is reduced since the over-taught membrane doesn’t transmit sound as well, resulting in that stuffy, plugged up feeling you get before the pop. That means you finally equalised at the 16th floor and had the opposite effect when you went back down. Yep… in Chinese medicine, onions slices are placed on people’s feet to help purify the body. The rationale is that onions have antibacterial properties, and its phosphoric acid enters into your bloodstream after being absorbed through your feet.

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