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Vitamin B12 is needed by human body for performing important functions like myelin formation, energy production, DNA synthesis and blood formation. However, if the levels of B12 remain low for a long time, B12 deficiency can lead to irreversible damage to nerve cells in brain.
Vitamin B12 helps the central nervous system in the manufacture of compounds called monoamines. In elderly people, B12 deficiency can cause reversible dementia and many cognitive problems. Mood disturbances, hyperactivity and psychosis are some of the neuropsychiatric disorders that are associated with B12 deficiency. Deficiency of vitamin B12 increases the homocysteine levels in your blood which makes you more vulnerable to cardiovascular and cerebrovascular diseases like stroke and heart diseases. As B12 plays an important role in DNA synthesis, B12 deficiency can lead to damage to DNA which is a risk factor for cancer.
Pregnant women deficient in B12 have a higher risk of having babies who have neural tube defects like spina bifida, which affects the spinal cord and brain. Cobalamin is the scientific name of vitamin B12, which is a water-soluble vitamin that resides in the kidneys, liver and other body tissues. The main goal of B12 deficiency treatment is to increase the level of vitamin B12 in your body.
AYTaking a supplement or changing your diet will be best if dietary factors are responsible for your B12 deficiency.
AYB12 injections will be prescribed to you by your doctor if the deficiency is caused by pernicious anemia or an absorption issue. AYB12 deficiency caused by Crohna€™s disease, alcoholism or celiac disease can be treated simply by treating these conditions. Deficiency of vitamin B12 can be avoided simply by increasing your intake of eggs, seafood, meat, dairy products and poultry. Raise awareness of this condition amongst doctors and the general public, so that people can be diagnosed appropriately. Explain the signs and symptoms that a doctor or person who is diagnosing themselves should look out for, and how to make sure that you reach the right diagnosis and don't confuse B12 deficiency with something else.
Ensure treatment is tailored to the needs of the patient, and where possible, make treatment available free at the point of need.
Look at some patient testimonials and television documentaries on the subject - you may recognise your own symptoms. Take the B12 deficiency protocol test (appendix 1) or the on-line calculator (which is no longer the best way to diagnose I'm afraid), then take the protocol to your GP to discuss. If you want to understand how cost-effective B12 replacement therapy is, then this might be a good place. Dr Chandy has been an NHS GP in Horden, County Durham, United Kingdom for 40years and during that time has amassed a wealth of experience. When people came with tiredness and unexplained neurological symptoms, Dr Chandy began to suspect something more and tested these people for the amount of vitamin B12 they had in their bloodstream.
Many many people have now benefited from vitamin B12 replacement therapy for a variety of conditions which you can find out about by exploring this site. She has bravely agreed to be filmed without her usual wig, but her memory is playing up because it is so long since her last injection. Frankie tells of how she suffered, the tests she had to endure until doctors worked out what was wrong, and what a difference it has made. The local MP (Grahame Morris MP for Easington - who was a BMS (BioMedical Scientist) in the labs at Sunderland Royal Infirmary) interviews people with B12 deficiency to hear their story (August 27 2010). The definitive and original guide to B12 deficiency, Dr Chandy interviewed by Chris Jackson of UK BBC Inside Out Team broadcast 31 Oct 2008.

Julia found her eyesight going as her eyes refused to focus on the same things as each other.
B12, or cobalamin, is an essential vitamin for the proper functioning and development of the brain the nerve cells ,body defense mechanisms, or red blood cell formation..
It is needed to convert carbohydrates into glucose in the body, thus leading to energy production and a decrease in fatigue and lethargy in the body. It helps in healthy regulation of the nervous system, reducing depression, stress, and brain shrinkage.
Vitamin B 12 helps protect against cancers including breast, colon, lung, and prostrate cancer. Vitamin B12 may support energy production by helping the body convert food into energy.* More energy will hopefully result in more exercise and greater motivation which will lead to safe and healthy weight control. Causes of vitamin B12 deficiency include not eating animal products, not making enough stomach acid , an autoimmune disorder called pernicious anemia, and certain medications, especially acid-blocking medications (proton pump inhibitors and H2 blockers) for gastro esophageal reflux and acid reflux, and Metformin for diabetes. Abnormal sensation, typically numbness, tingling or pricking (“pins and needles”) of the lower legs and feet (both sides) Weakness in the legs Increased risk of falling Dizziness Memory loss Attention deficits Irritability Depression Psychosis (suspiciousness, persecutory or religious delusions, auditory and visual hallucinations, and disorganized thought-processes) Sore, swollen, beefy red tongue Sores at the corners of the mouth Recurrent canker sores Burning sensation of the mouth ,Fatigue, Shortness of breath on exertion.
Unlike many other vitamins and minerals, cobalamin supplements do not cause a vitamin toxicity and even injecting large amounts of vitamin B12 does not cause health issues. If left untreated, the symptoms can worsen and low levels of B12 can lead to anemiaa€”your body does not have enough red blood cells. Peripheral neuropathy, Parkinson's disease, and migraine are neurological conditions caused by B12 deficiency. Females who have low levels of vitamin B12 may be at a higher risk of developing cervical and breast cancer.
Deficiency of vitamin B12 can also cause repeated miscarriages and are considered to be the main cause of infertility as well.
For instance, malnutrition and consuming a vegetarian diet that does not include any dairy products, fish, meat or eggs are common causes of B12 deficiency. For people who either do not eat meat or suffer from a disease which stops their body from absorbing this vitamin, eating cereals fortified with vitamin B12 at breakfast and taking B12-containing multivitamins is a good way to prevent B12 deficiency.
Although B12 supplements are funded on NHS, they are only funded for a very narrow group of conditions.
Since then the NHS has forced her doctor to withdraw B12 replacement therapy on a number of occasions, and she tells of her struggles with having B12 and then having it taken away.
My old cat Smudge chases the young cat again, climbs ladders (and climbs down herself), and is generally as fit as she was many years ago. The interviewer was at first surprised - people don't get awards for doing what they are paid to do - but she persisted. Here Jane describes the symptoms, and how she can't wait for her next B12 injection (in fact, she knows that she needs injections every 2 weeks because she's keeping a diary of the symptoms). She's been for all sorts of tests and treatment, but now that she's on B12 replacement therapy she's starting to see an improvement.
It plays an important role in the maintenance of the sheaths that cover and protect the nerves of the central and the peripheral nervous system, ensuring proper and faster nerve-impulse transmission. Vitamin B12 also protects against heart disease by curbing and improving unhealthy cholesterol levels, protecting against stroke, and high blood pressure.
Decreased bone health and increased risk of fracture Mild diarrhea or constipation Impaired vision Possible increased risk of cardiovascular disease. Animal products and fortified cereals help you reach this intake goal, and oral or injected vitamin B12 supplements also help boost your B12 levels. However, it is important to notify your doctor about the intake of B12 supplements, so they can prescribe some medicines that are not affected by these supplements. We show here and in our audits that a much wider range of conditions can beneficially be treated with Vitamin B12 replacement therapy.

We're restricted how often the GP can give injections, which is why we want to raise awareness.
According to Framingham Heart Study, around 25% of adults in the United States do not have sufficient quantities of this important nutrient and almost half of the US population does not have optimal levels of blood in their bodies. Getting enough B12 allows your body to make heme, a chemical component of hemoglobin, the protein that transports oxygen in your blood.
If you already have pernicious anemia, for example, you cannot efficiently absorb vitamin B12 through your digestive tract, so vitamin B12 injections offer an advantage over oral supplements. If you can properly absorb cobalamin, vitamin tablets are convenient and easy to take each day.
Vitamin B12 & Folic Acid Vitamin B Complex Rich Foods Does Niacin Help With Weight Loss? These vitamins exit your body through your urine on a daily basis, after your system uses what it needs. While B vitamins are generally safe, let your doctor know if you decide to take a supplement, as a precautionary measure.
Riboflavin is known as B-2, while niacin may be referred to as B-3 and pantothenic acid is commonly called B-5. Vitamin B-6 is a series of collective vitamin compounds, including pyridoxine, pyridoxal and pyridoxamine. Folic acid, or B-9, is the same as folate, but folic acid is synthetic, whereas folate is the natural form of the vitamin found in foods.
In its combined state, B-12 may be listed as a cobalamin in your vitamin B complex supplement. These vitamins work hand-in-hand to pull energy from carbohydrates, protein and fat from the foods you consume. You also need vitamin B complex in order to form new red blood cells, support nervous system functions and keep your skin and eyes healthy.
Folic acid is especially important for women of childbearing age, because it helps prevent neural tube defects, explains the Office of Dietary Supplements. Getting adequate folic acid in your diet each day is essential, because these defects occur during the first few weeks of pregnancy -- often before you are aware of a growing fetus. Your hydration status also has an influence on how long vitamin B complex sits in your system.
For example, drinking lots of water throughout the day and urinating frequently flushes out the B vitamins quickly.
Because your body excretes any excess of B vitamins throughout the day, getting too much is unlikely. In some cases, however, an excess of one vitamin may cause a deficiency or other problems with another vitamin or mineral. For example, excessive folic acid can mask the warning signs of a B-12 deficiency, says the Office of Dietary Supplements.
Even though B-12 is the one B vitamin your body stores, large doses are considered non-toxic.
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