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Over-the-counter allergy relief medications Claritin (Loratadine) and Zyrtec (Cetirizine) have similar effects, but their different ingredients mean that different groups of people have rare but adverse reactions to them.
Claritin and Zyrtec can also be used in dogs that suffer from a variety of allergic reactions or symptoms.
Treatment for Allergy symptoms caused by hay fever, hives, angioedema, and skin allergies.
Administration method Liquid syrup, tablets, and tablets designed to dissolve in the mouth. Inform the doctor If you have severe hepatic (liver) disorders or PKU (a rare genetic syndrome called phenylketonuria) or take other allergy medications. Side effects Claritin's most possible common side effects, which are typically not serious, include headache, feeling tired or drowsy, dry mouth, nervousness, stomach pain, diarrhea, eye redness, nosebleed, skin rash, and sore throat.
Zyrtec's common, less serious side effects can include drowsiness, dry mouth, sore throat, dizziness, headache, cough, nausea, or constipation. Excretion Claritin's is excreted about equally through the kidneys via urination and through the digestive system via feces (around 40% both ways); trace amounts of the drug, unmetabolized, may remain in the urine.
About 70% of Zyrtec is excreted via urination, with half of the drug remaining unmetabolized; another 10% is expelled through feces. Systematic (IUPAC) name Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate. Both Claritin and Zyrtec are used to treat allergy symptoms caused by hay fever, hives, angioedema, and skin allergies.
In studies, Claritin and Zyrtec have provided much greater allergy relief than placebo, usually with few side effects.
Zyrtec has been found to have positive, long-lasting effects compared to Allegra, with allergy symptoms still suppressed to varying degrees for up to 24 hours after initial dose. In a large study of over 800 adolescents between the ages of 12 and 15, a 30-day treatment with Zyrtec was found to severely reduce allergy symptoms. In one study, Zyrtec was found to be equally as effective as competing allergy relief drugs and superior to Claritin when it came to seasonal allergy relief. The cost of Claritin and Zyrtec varies depending on form; generic versions of both drugs are cheaper than the branded forms.
While both Claritin and Zyrtec have relatively few side effects, some individuals may have a reaction to the drugs—usually a mild side effect that will not require contacting a doctor.
A new side effect to these drugs may also be reported to US FDA at 1-800-FDA-1088 and Health Canada at 1-866-234-2345. For Claritin, serious side effects can include fast or irregular heartbeats, feeling faint, yellowing of skin or eyes (signs of jaundice), urinary retention, and seizures. Zyrtec's serious side effects may include a fast and heavy or irregular heart rate, extreme restlessness, uncontrollable shaking, sleep problems like insomnia, urinary retention, vision problems, and confusion. Allergic reactions to Claritin or Zyrtec are very rare, thus their over-the-counter status. At least one correlative study has found a potential link between antihistamine drugs, like Claritin and Zyrtec, and obesity.
Though Claritin and Zyrtec last for around 16 hours (8-hour half-life) in the body, the two drugs are metabolized differently.
Loratadine is the active ingredient in Claritin, while Cetirizine is the active ingredient of Zyrtec.

Cetirizine is an antihistamine that reduces the effects of natural chemical histamine in the body.
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More serious side effects are heart palpitations, insomnia, tremors, confusion and decreases in urine production. Those using muscle relaxants, sleeping pills, or other allergy medications should speak to a doctor before also using Zyrtec, while those suffering from liver disorders or phenylketonuria (PKU) should be careful with Claritin. They should reduce general allergy symptoms, such as sneezing, a runny nose, and eye irritation, that are common with allergic reactions to environmental factors or foods.
The two drugs have also, at times, outperformed similar allergy relief drugs or worked well alongside other drugs. Likewise, Zyrtec is available in both non-chewable and chewable forms, as well as in liquid syrup. For those taking other medication, including other allergy relief drugs, speaking to a doctor before taking Claritin or Zyrtec, too, is advisable. In the event of experiencing one of the side effects below, patients are advised to contact their doctor immediately. An allergic reaction to either of these drugs may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.
In contrast, about 70% of Zyrtec is excreted via urination, with half of the drug remaining unmetabolized; another 10% is expelled through feces. As Claritin is often used as a preventative medication, it may take several days for it to affect some patients.
Be careful if you drive or do anything that requires you to be alert.Drinking alcohol can increase certain side effects of cetirizine.
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I also have PCOS (polycystic ovarian syndrome), which I was diagnosed with at about 25 (I'm 37 now). Those experiencing allergic reactions to Claritin, Zyrtec, or any other drugs should contact emergency care immediately.
Further study is needed, but those concerned about their weight or who have noticed differences in their eating habits while on these drugs should consult a doctor. Zyrtec usually has faster results, but it, too, may take time, depending on severity of symptoms.
Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). AnswersAre there any corporate looking to buy quality emission offsets carbon credits to help reduce global warming and aid developing countries?
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Both should work very well within 5-7 days of use, and many will experience allergy relief on the first couple of days.
They can add to sleepiness caused by cetirizine.Call your doctor if your symptoms do not improve, if they get worse, or if you also have a fever.
Severe allergic reaction is the most dangerous of the Zyrtec side effects, and this usually presents with difficulty breathing, hives and facial swelling. Also, talk to your doctor about your complete medical history, especially if you have kidney. Wellbutrin xl, spironolactone, divigel, prometrium, xanax, nexium, metformin hydrochloride, zyrtec, depression withdrawal. Zyrtec is often used as an alternative to other over-the-counter cold medications because the risks of side effects are much lower than those of ingredients found in other medications.Over-the-counter Zyrtec is approved for use in children ages two and up, but pediatricians may choose to prescribe Zyrtec to infants and toddlers in certain situations. Always follow the dosage instructions exactly in these cases in order to reduce the incidence of serious side effects in children.Zyrtec for Chronic HivesChronic hives—also known as urticaria—is a condition that results in very itchy and sometimes painful whelps on one or more areas of the body.
The cause of chronic urticaria is often unknown, but clinical studies have shown that these hives are a response to increased levels of histamine in certain tissues. Since Zyrtec and cetirizine have been shown to decrease the effects histamine has on the body, these medications are often recommended as a long-term course of treatment to prevent and reduce the severity of chronic hives. Patients and their doctors should still monitor for the same side effects that occur in other treatments with the medication.Zyrtec is a wonderful alternative to other allergy medications that are known to cause significant drowsiness in both children and adults.

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