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Chronic fatigue syndrome is a condition of prolonged and severe tiredness or fatigue that is not relieved by rest and is NOT directly caused by other conditions. Chronic fatigue syndrome sufferers usually show multiple bilateral perfusion defects, but occasionally large unilateral perfusion abnormalites may be seen on SPECT studies.
In the SPECT study below a person with chronic fatigue syndrome shows extensive perfusion defects in the left cerebral hemisphere and left cerebellum (circles). The earlier a person with chronic fatigue syndrome receives medical treatment the greater the likelihood that the illness will resolve. Because these symptoms are shared with many other illnesses—and because many of these conditions lack a diagnostic test or biomarker—unraveling which illnesses are present can be difficult.
Chronic Fatigue Syndrome (CFS) is characterised clinically by constant, incapacitating fatigue (usually experienced as exhaustion and poor stamina) which is not relieved by bed rest and of at least six months duration. Chronic Fatigue Syndrome was formally defined in 1988 by a consensus panel convened by the Centres For Disease Control (CDC) and a formal and controversial set of diagnostic criteria was established.
Prolonged fatigue states are found in fibromyalgia, irritable bowel syndrome, anxiety and depression, as well as in chronic fatigue syndrome4. Since children and adolescents are in a dynamic developmental state, early diagnosis and intervention is vital when persistent, unexplained fatigue exists for three months or more (rather than six months as is the case with adults).
This "brain misperception" seems to be centered in the prefrontal cortex which regulates sensory gating as well as neurotransmitter secretion by neurons which secrete the excitatory amino acid glutamate resulting in a decrease of the neurotransmitter norepinephirine. Norepinepherine enhances the signal to noise ratio in the processing of sensory input by the brain5. The vertical axis shows the activation of the Autonomic Nervous System (ANS), ranging from arousal (fight-flight) to relaxation. The horizontal axis represents what is called the hypothalamic-pituitary-adrenal or HPA system, which coordinates the release of several of the body’s major hormones, including cortisol which is commonly referred to as the stress hormone. The cause of this type of prefrontal cortex dysfunction is usually an interaction of genetic, developmental and environmental factors. Neural plasticity is the ability of the brain to cope with changing demands by creating and doing away with neural pathways as necessary to meet those demands. Quantitative Electroencephalographic (QEEG) comodulation analysis of CFS sufferers indicates an increase in alpha in parietal regions and an anterior-posterior disconnection is present. An Australian study in 2002 reports that excessive 50Hz magnetic field exposure may contribute to the symptoms of CFS and decreased immune function13.. Chemical contaminants from outdoor sources: Outdoor air that enters a building can also be a source of indoor pollution. Chemical contaminants from indoor sources: Most indoor air pollution comes from sources inside the building. Biological contaminants: Biological contaminants include pollen, bacteria, viruses, and molds.
Inadequate ventilation: In the 1970s building designers were led to make buildings more airtight, with less outdoor air ventilation, in order to improve energy efficiency. It should also be noted that excessive exposure to cool white fluorescent light can cause fatigue as well as decreased immune function14.. In light of the above Nutritional Factors, a full metabolic workup will be necessary in order to formulate an individualised diet and supplementation regime specific to the needs of each individual.
A complete developmental and medical history during the diagnostic interview will need to be undertaken in order to better understand the underlying dynamics of your condition so as to plan the best approach for your individual needs. Since neural plasticity is compromised as noted in the neurological considerations of this article, eeg biofeedback (Neurofeedback) based upon QEEG findings will need to be undertaken. Breathing, posture, moderate levels of exercise and gentle bodywork therapies such as Bowen Therapy and CranioSacral Therapy have profound effects upon the body, generating a whole body response by activating the relaxation response to allow healing to take place. SCENAR Therapy, which is a reflex biofeedback therapy blending the best of Western electro-medicine and Eastern acupuncture, developed in Russia has a good history in relief of chronic pain. As chronic fatigue syndrome involves devitalisation and many bodily systems may be compromised, herbal medicine strategies have been developed41, 42, 43, 44, 45, 46, 47, 48, 49. At Learning Discoveries, our approach looks at guiding and educating the person in their own innate capacities to attain balance and wellbeing in their lives.
After a thorough history and psychometric assessment including a QEEG, an individualised programme will be devised aimed at restoring balance in the autonomic nervous system, and outlook. Chronic fatigue syndrome (CFS) is generally characterized by long-term fatigue that does not get resolved by rest. People suffering from chronic fatigue syndrome should seek medical attention as it may lead to more serious complications and make treatment more difficult. The chances of recovery significantly vary with every sufferer, but it has been found that adolescents have better prognosis than adults, as improvement occurs a year or two after diagnosis.
The syndrome is primarily manifested by extreme exhaustion that does not improve even with ample rest.
Diagnosis is a bit tricky for CFS sufferers because other health conditions also have the same symptoms.
If the symptoms are not caused by other medical, mental or sleeping disorder, the doctor will compare the symptoms to the guidelines for diagnosing CFS.
Some alternative treatment methods for Chronic Fatigue Syndrome are gaining popularity these days due to their effectiveness. Studies showed that people suffering from CFS have low levels of L-carnitine which is thought to be responsible for muscle pain and fatigue which makes the individual tire easily after exercise.
This herb has long been used in fighting fatigue and in increasing a person’s energy level. Essential fatty acid supplements are used in correcting the disorder naturally to recompense the loss 6-desaturated EFAs due to viruses.


This compound is not just an antioxidant but also helps in producing ATP which is the main source of energy in body cells. This website is purely for information purpose and gives information that is general in nature. Chronic pain extends beyond the usual recovery period for an injury or illness that can go on for months or years.
Chronic illness is a persistent medical condition that people have to manage on a daily basis. While working as a medical social worker my interactions with doctors and medical staff helped me to gain a greater understanding into how chronic illness and chronic pain impact everyone in the family. The question how to Recognize Chronic Fatigue Syndrome Symptoms has been asked 772 times by our users.
Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by intense that cannot be cured with sleep.
Oct 18, 2013 · Fibromyalgia and chronic fatigue syndrome come with a host of symptoms that can leave you wondering what in the world is going on your body! Nimodipine is a dihydropyridine calcium channel blocker that was originally developed for the treatment of high blood pressure. Although chronic fatigue syndrome (CFS) was first named in the 1980s, it is not a new disease and has been referred to by other names since 1700s.
Aug 29, 2014 · Get information about chronic fatigue syndrome (CFS) symptoms, Epstein Barr, Treatment, Support, Weakness, Diet, Cure, and more. Aug 25, 2014 · Through my healing process I have experienced the biggest shifts and greatest miracles by redefining what a happy successful life is to me. To be diagnosed with chronic fatigue syndrome, your fatigue must be severe enough to decrease your ability to participate in ordinary activities by 50% or more. Equally important, about 40% of people in the general population who report symptoms of chronic fatigue syndrome have a serious, treatable, previously unrecognized medical or psychiatric condition. PEM occurs following mental or physical exertion and is described as worsening symptoms lasting 24 hours or more. They experience difficulties with attention, concentration and memory that have been linked to problems in how the brain processes information – particularly processing speed and complex information processing. Seek care first from the health care provider who knows you best and will work with you to rule out other possible causes of symptoms and identify other conditions. Acupuncture, hydrotherapy, yoga, tai chi, and massage therapy have been found to help and are often prescribed for symptom management. One of the main complaints laid down against the set of criteria was that it was better suited to research than for clinical purposes2.. CFS by its nature cannot be classified medically as a disease and yet it is characterised by a set of "recognisable symptoms that cannot be attributed to any alternative condition"4. Issues such as autonomy, self-esteem, body image, socialisation, sexuality and academic goals are of central importance and the longer the diagnosis is delayed, the greater the adverse consequences of these issues 4. The ANS is a quick-acting system that affects the heart, digestive system, adrenaline secretion and many other bodily functions. This axis is influenced by the quality of our emotions - it is a slower-acting system than the ANS, but its effects are longer-lasting.
Additionally, due to the inherent reduction in neural plasticity associated with this type of dysfunction, there is usually an increased susceptibility to environmental stressors. This relates to the concept of allostatic loads being exceeded beyond the coping capacity of the person. Pollutants from motor vehicle exhausts, plumbing vents, and building exhausts (bathrooms and kitchens) can enter the building through poorly located air intake vents, windows, and other openings. For example, adhesives, upholstery, carpeting, copy machines, manufactured wood products, cleaning agents and pesticides may emit volatile organic compounds (VOCs) including formaldehyde. These contaminants can breed in stagnant water that has accumulated in humidifiers, drain pans, and ducts, or where water has collected on ceiling tiles, insulation, or carpet. These reduced ventilation rates have been found to be, in many cases, inadequate to maintain the health and comfort of building occupants.
Therefore, cool white fluorescents should be replaced with full spectrum fluorescents which approximate the spectrum of light found in daylight. Provocative testing of CFS sufferers found that in many instances, specific foods are associated with specific symptoms41..
EEG biofeedback normalises sleep patterns and allows the brain to become self-regulating and more adaptive rather than being reactive and "stuck". Ali, M., Ascorbic acid reverses abnormal erythrocyte morphology in chronic fatigue syndrome.
Jessop, C., Super Malate and Chronic Fatigue, Fibromyalgia Network Newsletter, compendium#2, Oct 1990-Jan. Judy, W., South Eastern Institute of Biomedical Research, Bratenden Florida, Presentation to the 37th annual meeting, American College of Nutrition, Oct, 13, 1996. Bone, K., A Clinical Guide To Blending Liquid Herbs, Churchill Livingstone Publishers, 2003.
The feeling of exhaustion tends to get worse when doing any kind of mental or physical activity.
Those suspected to be suffering from the disease will be evaluated thoroughly to rule out other health conditions whose symptoms resemble that of CFS.
There had been various presumptions about its cause, but experts believed that the syndrome develops due to a combination of several contributing factors. However, it has been found to commonly occur between 30 and 50 years of age, affecting 2 in every 1,000 people.


One the other hand half of adult CFS patients get better from the syndrome and live normally within 5 years.
This severe fatigue is experienced for 6 months or longer and greatly affects the social, secular and personal life of the afflicted individual.
It is for this reason that doctors conduct an array of tests to ensure that the symptoms are not caused by other medical problems, such as diabetes, hypothyroidism, anemia, anxiety, depression, bipolar disorder, schizophrenia, insomnia, restless leg syndrome and obstructive sleep apnea. Please contact your health care provider for specialized medical advice, diagnosis and treatment. Relaxation techniques and EMDR are valuable tools to help manage pain and illness, and the stress associated with them.
Chronic fatigue syndrome is a complex condition characterized by extreme, long-lasting exhaustion. Sleep problems, pain, heart rate irregularities, gastrointestinal difficulties, allergies, and depression are some of the symptoms that can be relieved treated.
Symptoms often wax and wane, but are usually severely debilitating and may last many months or even years. Symptoms of CFS are currently believed to be the result of disturbed brain function and the pathophysiology of CFS is currently unknown.
What this means is that information from both inside and outside the body is misperceived by the brain, which results in inappropriate sensations being experienced by the person.
Norepinepherine and Substance P (which is largely involved in the sensation of pain) are reciprocal in relation to one another, in that if one is high, the other is low. Perceptions and emotions activate the ANS and subsequently affect the balance between its sympathetic and parasympathetic branches6..
DHEA promotes the healthy maintenance and regeneration of the body’s systems, including activation of osteoblasts and the inhibition of Interlukin-6 implicated in osteoporosis. Further, some clinical studies have suggested an overlap between CFS and multiple chemical sensitivity (MCS)11 , 12.. Research shows that some VOCs can cause chronic and acute health effects at high concentrations, and some are known carcinogens. Biological contaminants can cause fever, chills, cough, chest tightness, muscle aches, and allergic reactions. Chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities in a community-based sample of persons with chronic fatigue syndrome-like symptoms.
One of the studies revolves around certain viruses, which include the HHV-6 virus (or human herpes virus-6), the Epstein-Barr virus and the virus that causes mouse leukemia. Studies also show that the syndrome is more common among women than men, and this is because females are more likely to report their symptoms than males. The treatment for the condition may involve taking medications like sleeping pills for those with sleeping problems and antidepressants to combat depression. Managing pain, fatigue, medical appointments, special diets and medications can be overwhelming for both patients and family.
Therefore, CFS is probably best regarded as "dis-ease"— a subjective state that can only be defined by reference to the person — rather than a "disease".
Other substances which tend to be reciprocal in balance are the hormones Dehydroepiandrosterone (DHEA) and Cortisol (Cortisol is sometimes known as the stress hormone). Low to moderate levels of multiple VOCs may also produce acute reactions in sensitive individuals. One indoor air bacterium, Legionella, has caused both Pontiac Fever and Legionnaire’s Disease. Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome. Scientists are also still trying to establish the connection between genetics, environmental factors, stress and previous bouts of illnesses in the development of CFS. Certainly, individuals should seek medical advice upon experiencing the symptoms linked to the disorder. Furthermore, people living sedentary lifestyles, those who are overweight and individuals who are under stress, will most likely suffer from CFS than any other group of people. When we experience any pain, it is in both our bodies and minds – we cannot separate the physical and psychological affects they have on us. As yet, no medication has been shown to provide long term remission or "cure" in people with CFS. Environmental tobacco smoke and combustion products from stoves, fireplaces, and unvented space heaters all can put chemical contaminants into the air. The patient may have to go through psychological counseling and graded exercise programs for strength and stamina. Pain can also affect our relationships, finances, and employment, which leads to increased anxiety and depression.
Therefore, conventional medical treatments for CFS are empirical and careful monitoring is required to ensure that the symptomatic benefits outweigh any side effects. Furthermore, many people with CFS report an increased susceptibility to drug side effects4.




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