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In this article, we discuss the applications of LLLT as well as its efficacy for a number of cosmetic and dermatological conditions, including the treatment of alopecia (hair loss) , cellulite, and undesirable fat deposits. Acyclovir treatment of acute herpes zoster speeds rash healing and decreases pain and ocular complications.
Valacyclovir hydrochloride is rapidly converted to acyclovir which has demonstrated antiviral activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella-zoster virus (VZV) both in vitro and in vivo. My valacyclovir generic to acyclovir conversion boyfriend a velvetlined deluxe very tiny number either 50 rogaine generic form.
Oral valacyclovir, which is converted in the body to acyclovir, has greater oral bioavailability than oral acyclovir and compared with oral acyclovir yields similar acyclovir plasma concentrations with less frequent (twice-daily) dosing. If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. Find patient medical information for acyclovir oral on including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Herpes zoster (shingles) is a painful rash caused by the same virus that causes chickenpox. Find patient medical information for Zovirax oral on including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Acyclovir cream is used to treat cold sores (fever blisters; blisters that are caused by a virus called herpes simplex) on the face or lips. Cold sore FAQs, including cold sore causes, cold sore cures, and cold sore myths – your questions answered at Zovirax. Commonly known as cold sores or fever blisters, RHL typically manifests through reactivation of initial exposure to HSV-1, often triggered by stimuli such as sunlight, stress, menses, or trauma to the affected area. Zovirax Cold Sore Cream can help to prevent a cold sore appearing if used at the tingle stage (this is when you feel a tingling, burning or itching sensation). ACYCLOVIR CREAM – TOPICAL (Zovirax) side effects, medical uses, and drug interactions. Compare prices and print coupons for valacyclovir (Valtrex) and other Shingles, Herpes, and Cold Sores drugs at CVS, Walgreens, and other pharmacies. This discount prescription Valacyclovir Card work just like a coupon at your local pharmacy. For recurrent outbreaks of genital herpes, valacyclovir works best if it is used within 24 hours after the symptoms begin to appear. Zovirax tablets are available in 200, 400 and 800 mg strengths and as a liquid suspension with 200 mg strength per 5 ml. Acyclovir is most commonly used to control and prevent outbreaks of genital herpes, but may also be used to help combat chicken pox or the shingles virus. Shingles requires treatment with higher doses of acyclovir, and the most common side effects at higher doses are tiredness and malaise. Acyclovir is a nucleoside analogue and antiviral agent used in therapy of herpes and varicella-zoster virus infections. Valacyclovir hydrochloride is the hydrochloride salt of L-valyl ester of the antiviral drug acyclovir.
Cold Sores (Herpes Labialis): Valacyclovir is indicated for treatment of cold sores (herpes labialis). Initial Episode: Valacyclovir is indicated for treatment of the initial episode of genital herpes in immunocompetent adults. Recurrent Episodes: Valacyclovir is indicated for treatment of recurrent episodes of genital herpes in immunocompetent adults.
Suppressive Therapy: Valacyclovir is indicated for chronic suppressive therapy of recurrent episodes of genital herpes in immunocompetent and in HIV-infected adults. Reduction of Transmission: Valacyclovir is indicated for the reduction of transmission of genital herpes in immunocompetent adults. Herpes Zoster: Valacyclovir is indicated for the treatment of herpes zoster (shingles) in immunocompetent adults. Cold Sores (Herpes Labialis): Valacyclovir is indicated for the treatment of cold sores (herpes labialis) in pediatric patients a‰?12 years of age. Cold Sores (Herpes Labialis): The recommended dosage of valacyclovir for treatment of cold sores is 2 grams twice daily for 1 day taken 12 hours apart. Initial Episode: The recommended dosage of valacyclovir for treatment of initial genital herpes is 1 gram twice daily for 10 days.
Recurrent Episodes: The recommended dosage of valacyclovir for treatment of recurrent genital herpes is 500 mg twice daily for 3 days.
Suppressive Therapy: The recommended dosage of valacyclovir for chronic suppressive therapy of recurrent genital herpes is 1 gram once daily in patients with normal immune function.
Reduction of Transmission: The recommended dosage of valacyclovir for reduction of transmission of genital herpes in patients with a history of 9 or fewer recurrences per year is 500 mg once daily for the source partner.
Herpes Zoster: The recommended dosage of valacyclovir for treatment of herpes zoster is 1 gram 3 times daily for 7 days.
Cold Sores (Herpes Labialis): The recommended dosage of valacyclovir for the treatment of cold sores in pediatric patients a‰?12 years of age is 2 grams twice daily for 1 day taken 12 hours apart. Valacyclovir caplets 500 mg, cherry flavor, and Suspension Structured Vehicle USP-NF (SSV). Dosage recommendations for adult patients with reduced renal function are provided in Table 1 [see Use in Specific Populations]. Hemodialysis: Patients requiring hemodialysis should receive the recommended dose of valacyclovir after hemodialysis. Peritoneal Dialysis: There is no information specific to administration of valacyclovir in patients receiving peritoneal dialysis. Valacyclovir hydrochloride is rapidly converted to acyclovir which has demonstrated antiviral activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella-zoster virus (VZV) both in vitro and in vivo. The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. Safety and effectiveness of valacyclovir in pre-pubertal pediatric patients have not been established. In a clinical study of herpes zoster, the duration of pain after healing (post-herpetic neuralgia) was longer in patients 65 and older compared with younger adults. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored [see Dosage and Administration, Adverse Reactions].
Central nervous system adverse reactions, including agitation, hallucinations, confusion, delirium, seizures, and encephalopathy, have been reported in elderly patients with or without reduced renal function and in patients with underlying renal disease who received higher than recommended doses of valacyclovir for their level of renal function. Elimination: The pharmacokinetic disposition of acyclovir delivered by valacyclovir is consistent with previous experience from intravenous and oral acyclovir. Renal Impairment: Reduction in dosage is recommended in patients with renal impairment [see Dosage and Administration, Use in Specific Populations]. Following administration of valacyclovir to volunteers with ESRD, the average acyclovir half-life is approximately 14 hours.
Hepatic Impairment: Administration of valacyclovir to patients with moderate (biopsy-proven cirrhosis) or severe (with and without ascites and biopsy-proven cirrhosis) liver disease indicated that the rate but not the extent of conversion of valacyclovir to acyclovir is reduced, and the acyclovir half-life is not affected. The 1 gram tablets are white, film-coated, oval shaped tablets with a partial break line on both sides. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.
Skin cancer can occur anywhere on the body, but it is most common in skin that is often exposed to sunlight, such as the face, neck, hands, and arms. Common signs and symptoms associated with skin aging include skin wrinkling, skin dyspigmentation, telangiectasia, and reduced tissue elasticity.
Nikogosyan DN, Kapituletz SP, Smirnov YA: Effects of ultraviolet laser radiation on Venezuelan equine encephalomyelitis virus.
The antiviral medications available in pill form acyclovir, valacyclovir, famciclovir have been specifically developed for the treatment of genital herpes. Valaciclovir, the l-valyl ester of acyclovir, is rapidly and almost completely converted to acyclovir in vivo and gives three- to fivefold increases in acyclovir bioavailability. It treats cold sores around the mouth (caused by herpes simplex) , shingles (caused by herpes zoster) , and chickenpox. It slows the growth and spread of the herpes virus so that the body can fight off the infection.
Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.
Three antiviral drugs are used to treat shingles: acyclovir (Zovirax) , famciclovir (Famvir) , and valacyclovir (Valtrex).
ZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses.
Pictures of Zovirax Ointment (Acyclovir Ointment) , drug imprint information, side effects for the patient.
It is used to treat skin infections with the herpes simplex virus, for example cold sores and genital herpes (caused by herpes simplex virus types 1 and 2). Acyclovir ointment is used to treat first outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time) and to treat certain types of sores caused by the herpes simplex virus in people with weak immune systems. Cold Sores (Nongenital Herpes Simplex Infections) Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as cold sores and fever blisters. Cold sores, also known as herpes labialis or fever blisters, are highly infectious sores on the lip and outer edge of the mouth.
An FDA-approved antiviral, acyclovir cream has demonstrated reduced lesion healing time and duration of pain. Compare valacyclovir prices, print discount coupons, find manufacturer promotions and details on available patient assistance programs. It is only of limited efficacy against EBV and CMV; however, valacyclovir has recently been shown to lower or eliminate the presence of the EpsteinBarr virus in subjects afflicted with acute mononucleosis, leading to a significant decrease in the severity of symptoms. Usual doses are 800 mg every 4 hours, 5 times a day for 10 days for shingles; doses for genital herpes infection are the same interval but start with 200 mg.

The typical recommended oral dose in adults for genital or oral herpes simplex is 200 to 800 mg three to five times daily for 5 to 10 days; the usual prophylactic dose is 400 mg twice daily. Each caplet contains valacyclovir hydrochloride equivalent to 500 mg or 1 gram valacyclovir and the inactive ingredients carnauba wax, colloidal silicon dioxide, crospovidone, FD&C Blue No. The efficacy of treatment with valacyclovir when initiated more than 72 hours after the onset of signs and symptoms has not been established.
The efficacy of treatment with valacyclovir when initiated more than 24 hours after the onset of signs and symptoms has not been established. The efficacy and safety of valacyclovir for the suppression of genital herpes beyond 1 year in immunocompetent patients and beyond 6 months in HIV-infected patients have not been established. The efficacy of valacyclovir for the reduction of transmission of genital herpes beyond 8 months in discordant couples has not been established. The efficacy of valacyclovir when initiated more than 72 hours after the onset of rash and the efficacy and safety of valacyclovir for treatment of disseminated herpes zoster have not been established. Based on efficacy data from clinical studies with oral acyclovir, treatment with valacyclovir should be initiated within 24 hours after the onset of rash. Therapy was most effective when administered within 48 hours of the onset of signs and symptoms. In patients with a history of 9 or fewer recurrences per year, an alternative dose is 500 mg once daily. Therapy should be initiated at the earliest sign or symptom of herpes zoster and is most effective when started within 48 hours of the onset of rash. During hemodialysis, the half-life of acyclovir after administration of valacyclovir is approximately 4 hours.
This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Elderly patients are more likely to have reduced renal function and require dose reduction. Caution should be exercised when administering valacyclovir to geriatric patients, and dosage reduction is recommended for those with impaired renal function [see Dosage and Administration, Use in Specific Populations].
Dosage reduction is recommended when administering valacyclovir to patients with renal impairment [see Dosage and Administration, Use in Specific Populations]. Caution should be exercised when administering valacyclovir to patients receiving potentially nephrotoxic drugs. Valacyclovir should be discontinued if central nervous system adverse reactions occur [see Adverse Reactions, Use in Specific Populations]. Acyclovir bioavailability from the administration of valacyclovir is not altered by administration with food (30 minutes after an 873 Kcal breakfast, which included 51 grams of fat). Acyclovir is converted to a small extent to inactive metabolites by aldehyde oxidase and by alcohol and aldehyde dehydrogenase. Following the oral administration of a single 1 gram dose of radiolabeled valacyclovir to 4 healthy subjects, 46% and 47% of administered radioactivity was recovered in urine and feces, respectively, over 96 hours. The pharmacokinetics of acyclovir following single- and multiple-dose oral administration of valacyclovir in geriatric volunteers varied with renal function. After nonmelanoma skin cancer has been diagnosed, tests are done to find out if cancer cells have spread within the skin or to other parts of the body. Honestly I would say its your boyfriends since it take a couple of days for the egg to implant and sperm can survive up to 5 days. Any input anyone may have as to what else this may be, I am losing sleep over the thought of skin cancer.
Beeson WH, Rachel JD: Valacyclovir prophylaxis for herpes simplex virus infection or infection recurrence following laser skin resurfacing. Valacyclovir is rapidly converted to acyclovir, which has in vitro and in vivo inhibitory activity against human herpes viruses including herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) , and varicella-zoster virus (VZV). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.
Orally administered, valacyclovir is rapidly converted to acyclovir which inhibits viral DNA replication after further conversion to the nucleotide analog acyclovir triphosphate by viral thymidine kinase, cellular guanyl cyclase, and a number of other cellular enzymes. Famciclovir and valacyclovir offer improved oral bioavailability and convenient oral dosing schedules but are more expensive than acyclovir. Care should be taken if you are taking high doses of Aciclovir, as blood levels of both drugs may increase. Advice for patients on this medication (brand name Zovirax) used to treat herpes infections. Aciclovir is an antiviral medicine, which acts on infected cells by stopping the virus growing. Treat Genital Herpes in complete confidence with Aciclovir and Valaciclovir Treatments from Co-operative Online Doctor. ZOVIRAX (acyclovir) Capsules, Tablets, and Suspension are formulations for oral administration. Acyclovir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses.
Learn about Zovirax (Acyclovir) , dosing, proper use and what to know before beginning treatment.
Zovirax (Acyclovir 5 cream) is also FDA approved for the treatment of recurrent cold sores. Despite their name, cold sores (also known as fever blisters) are not caused by the common cold.
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High-Dose, Short-Duration, Early Valacyclovir Therapy for Episodic Treatment of Cold Sores: Results of Two Randomized, Placebo-Controlled, Multicenter Studies.
10 Famciclovir, despite its favorable intracellular pharmacokinetics, must be given twice daily to be effective. Median Number of Reported AEs Describing Safety and Tolerance of Valacyclovir (VACV) , Evaluated by the Number Adverse Events, Administered at a Dose of 2. Patients are instructed to consult with their physician if they experience severe or troublesome adverse reactions, they become pregnant or intend to become pregnant, they intend to breastfeed while taking orally administered acyclovir, or they have any other questions. Zovirax may be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Acyclovir is in pregnancy category B which means that it is generally safe to use while pregnant, though there have not been satisfactory studies to confirm this. Oral aciclovir 800mg five times a day for 7 days accelerates the rate of healing of blisters.
The oral acyclovir dosage for treatment of primary or initial nonprimary genital herpes is 200 mg five times daily for 10 days. The dose currently approved by the Food and Drug Administration for use in this population for this indication is 10 mgkg per dose, dosed ever 8 hours, but there have been studies that have indicated that a dose of 20 mgkg per dose every 8 hours is more effective, said Dr. 2 Lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide. The efficacy of valacyclovir for the reduction of transmission of genital herpes in individuals with multiple partners and non-heterosexual couples has not been established. Therapy should be initiated at the earliest sign or symptom [see Use in Specific Populations]. About one third of acyclovir in the body is removed by dialysis during a 4-hour hemodialysis session. The removal of acyclovir after CAPD and CAVHD is less pronounced than with hemodialysis, and the pharmacokinetic parameters closely resemble those observed in patients with end-stage renal disease (ESRD) not receiving hemodialysis. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes.
In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored.
Approximately one third of acyclovir in the body is removed by dialysis during a 4-hour hemodialysis session. Dose reduction may be required in geriatric patients, depending on the underlying renal status of the patient [see Dosage and Administration, Use in Specific Populations].
Take time to learn about your treatment options and be sure to ask questions about things that are unclear. If the wearer required face protection, some helmets provided the ability to attach a buffe, which covered the throat and face.
Acyclovir is converted to its triphosphate form, acyclovir triphosphate (ACV-TP) , which competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates the viral DNA polymerase. Before the 1970s, when acyclovir (Zovirax) was introduced as an antiviral drug, cutaneous HSV infection was managed with drying agents and other local care. Aciclovir 200mg and 400mg tablets are used to: treat or prevent herpes simplex infections of the skin and mucous membranes e.
Compare herpes antiviral drugs: differences and similarities of Acyclovir (Zovirax) , Valacyclovir (Valtrex) and Famciclovir (Famvir). Herpes labialis, or cold sores, are caused by herpes simplex virus type 1 (HSV-1) and can result in significant irritation, pain, discomfort, and worry (18, 25). 3 days as the reference and compared it with a loading dose of 1000 mg of valacyclovir given twice a day for 1 day only. Researchers have not studied acyclovir use by pregnant women, so there’s not enough evidence to say that it is safe to take during pregnancy. Our Zovirax Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. A pregnancy registry of more than 1000 women who received aciclovir before or during early pregnancy showed no increased rates of miscarriage or birth defects in offspring. Burning pain typically precedes the rash by several days and can persist for several months after the rash resolves.

Ericson explained that there was no control group cohort because as high-dose acyclovir is used for at least 14 days, typically only with evidence of HSV disease, there is no obvious control group to use for comparison. Safer sex practices should be used with suppressive therapy (see current Centers for Disease Control and Prevention [CDC] Sexually Transmitted Diseases Treatment Guidelines). Therefore, supplemental doses of valacyclovir should not be required following CAPD or CAVHD.
With respect to CNS adverse events observed during clinical practice, agitation, hallucinations, confusion, delirium, and encephalopathy were reported more frequently in elderly patients.
Plasma concentrations of unconverted valacyclovir are low and transient, generally becoming non-quantifiable by 3 hours after administration.
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Acyclovir is slowly and poorly absorbed from the gastrointestinal tract and bioavailability decreases with increasing dose.
Aciclovir is used to treat two common viral infections – varicella-zoster and herpes simplex. What is zovirax, Purchase What is zovirax online from an approved certified pharmacy, fast Shipping, discount prices, fast shipping pharmacy.
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The recommended dosages for acyclovir, famciclovir and valacyclovir are provided in Table 1. This is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase.
Talking with your doctor is often the best way to learn about the medications prescribed for you, their purpose, and their potential side effects or interactions with other medications. I used to really dislike the word contentment, Taupin says, because I always thought it meant you had nothing more to do.
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To evaluate the prophylactic role of long-term ultra-low-dose acyclovir for varicella zoster virus (VZV) disease after allogeneic hematopoietic stem cell transp.
However, it does not clear the virus from your body completely, and does not have any effect once you stop taking it.
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For treating chicken pox in adults and children who weigh more than 40 pounds: 800 mg four times daily for 5 days.
Side effects, that may go away during treatment, include nausea, vomiting, diarrhea, or headache. 400 mg acyclovir take one tablet by mouth three times daily for 5 days, then as needed for outbreaks.
For acute episodes the recommended dosage of acyclovir is 200 mg taken five times per day for approximately ten days, possibly longer. The greater antiviral activity of acyclovir against HSV compared to VZV is due to its more efficient phosphorylation by the viral TK.
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Two-Day Regimen of Acyclovir for Treatment of Recurrent Genital Herpes Simplex Virus Type 2 Infection. Fever blisters and cold sores are manifested by a sudden appearance of clusters of small water blisters on the skin, lips, genitals, or other areas. For fear that b if of acquaintance with acyclovir in subcutaneous fat a provincial reaction.
Checkout the coupon savings our Card Holders have realized below (these are actual filled prescriptions over the past 90 days) : Drug Name Generic? While acyclovir has been a mainstay herpetic treatment for years, we tend to prefer the newer prodrug valacyclovir. Q: Can you please tell me if there are any long-term side effects to taking 800mg of acyclovir each day? If used within 24 hours after appearance of typical chickenpox rash, acyclovir is indicated for treatment of the Varicella Zoster or chickenpox virus. Acyclovir is a purine nucleoside analogue with viral static effects against human herpes infections. When radiation therapy is used to treat skin cancers, it is often done with a type of radiation called electron beam radiation. Orgabout loans u can pay on every month A combination treatment from the drugmaker for melanoma, thedeadliest form of skin cancer, has won priority review from U.
The oral dose used to treat shingles is 800 mg taken five times a day for seven to ten days (until the rash has crusted over). Acyclovir (Zovirax) : Acyclovir has been studied and used for many years as a treatment for shingles. The standard course of antiviral therapy for recurrent genital herpes requires administration of multiple doses of medication for 5 days.
Keep the fever blister lubricated as it heals, with ointment such as petroleum jelly or lip balm containing SPF 15 or higher. Most of the time, cold sores, also called fever blisters, are caused by HSV-1, while genital herpes, a sexually transmitted disease, is caused by HSV-2. In children, it is used to treat cold sores around the mouth (caused by herpes simplex) and chickenpox (caused by varicella zoster).
Radiation therapy can also be useful for some patients who, because of poor general health, can’t have surgery. While there is no cure for herpes simplex virus (HSV) infections, there are various treatment options available.
It is an antiviral medication that helps to reduce the pain and severity of herpes lesions or sores. Some cases require more aggressive treatment, and your doctor could prescribe Zovirax, Denavir or other antiviral creams and medications to reduce this painful condition. Women with active herpetic lesions during delivery are at the highest risk of transmitting the infection to the baby, so those women will be encouraged to have a cesarean delivery. Radiation may also be used to help treat skin cancer that has spread to lymph nodes or other organs.
Resumption of acyclovir upon restarting immunosuppressive therapy might be important for the further prevention of VZV reactivation. A dose of 200 mg aciclovir should be taken four times daily at approximately six-hourly intervals. Cutaneous herpes zoster infection is a problem frequently encountered in clinical practice. For women with recurrent genital herpes, the suggested dose of acyclovir is 400 mg, three times daily, starting around the 36th week of pregnancy. Therapy with a high dose of oral acyclovir (800 mg five times per day for 10 days) has been reported to shorten the duration of viral shedding, decrease the formation of new vesicles, and reduce the incidence of postherpetic neuralgia, without serious adverse effects. Herpes is a virus that infects the nervous system, modifying the DNA of the nerve cells supplying the skin through which the virus entered.
An extensive clinical trial program combined with 5 years’ postmarketing experience with valacyclovir provides evidence of favorable safety and efficacy in herpes simplex virus (HSV) management. Acyclovir is much less toxic for normal cells because less is drug is taken up, less is converted to active form, and normal cell enzymes are less sensitive to the chemical (to paraphrase the PDR online). As for all drugs considered for administration during pregnancy, the physician should assess the risk versus benefit for mother and fetus in each individual clinical situation.
Antiviral medication is most effective if it is taken when you first notice the prodromal symptoms (tingling and pain) of a recurrent genital herpes outbreak and if they are taken for the next 5 to 7 days or until symptoms go away. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. This medication delivers acyclovir more efficiently so that the body absorbs much of the drug, which has the advantage of taking the medication fewer times during the day. Zovirax is a prescription drug that is used to treat different herpes infections and also to treat herpes zoster (shingles) and chickenpox. It treats but not cures herpes infections by alleviating the symptoms of the condition, such as pain and itching.

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