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April 14, 2012 by Doc 1 Comment I had a patient the other day, I'll call her Sally, who was a new patient and had been recommended by a friend. She told me she had been to several different physicians, tried different medications, ate different foods, exercised, and tried numerous other interventions that didn't change they way she felt.
She was told that her thyroid lab (TSH) was normal, that there wasn't anything wrong with her thyroid, and they couldn't find anything wrong. I can't imagine knowing that something is wrong but the people who are supposed to be able to help can't find the problem and can't help. In order to understand how your labs can be 'normal' and you still feel bad AND why your doctor doesn't check any further, you have to understand your thyroid and how it works.
The thyroid gland is located in the front of the neck and is responsible for secreting appropriate amounts of thyroid hormones.
The thyroid gland releases primarily Thyroxine (T4) but does release a small amount of Triiodothyronine (T3). When T4 levels are detected as low, the pituitary sends more TSH to the thyroid to try to increase the amount of T4 release.
There are several 'patterns' of thyroid dysfunction and they are treated based on fixing the cause the dysfunction. The pituitary isn't working right for any number of reasons and isn't sending TSH to stimulate the thyroid gland. T4 has to be converted to T3 but the process is disrupted for any number of reasons (see below).
Thyroid resistance occurs when the all of the appropriate labs have been obtained but the levels are normal. Since the problem here is that we are making too much RT3 from T4, giving more T4 can actually make the problem worse! Remember, the key to addressing the problem is to identify the problem and customize the treatment for each patient based on what is wrong. I hope this information helps you to understand the issues with the thyroid gland and HOW it can malfunction as well as appropriate treatment to improve your overall health.
What Your Hands Can Tell You About Your FoodIf you’ve read any of my stuff or hear me talk at all then you know I recommend eliminating (or dramatically reducing) gluten from your diet. He asked another Pfizer chemist, Willard Welch, to synthesize some previously unexplored tametraline derivatives.
Welch then prepared stereoisomers of this compound, which were tested in vivo by animal behavioral scientist Albert Weissman. The key to fixing the problem with thyroid dysfunction is to identify the specific problem in the first place.
The thyroid hormones have an effect on every cell in the human body and function as a gas pedal, so to speak, to increase or decrease the metabolic activity of the cells. T4 has minimal physiologic effect and is converted to the much more metabolically active T3.
Conversely, when T4 is elevated, the pituitary decreases TSH release so that T4 release will decrease. First, it consumes too much of the T4 and makes a substance that has no thyroid effect (RT3).
I usually recommend stopping all T4 supplementation (including Armour thyroid) and then start working on why RT3 is being over produced. You have have symptoms of thyroid problems and go to your doctor to have a 'thyroid' test performed. My experience has been that thyroid problems have been inadequately worked up and so the appropriate diagnosis cannot be made.
I have a lot of patients who ask me if I’ll test them for Celiac disease or gluten intolerance. Occasionally I’ll have someone come in with a vague abdominal pain or some other abdominal symptoms. O'Keefe uses a variey of techniques including Instrument Adjusting, Myofascial Release, Flexion-Distraction, Thompson Drop, and Activator techniques. As a choreographer and dance instructor for many years, her understanding of a dancer and athlete's training, psyche, typical injuries, and kinetic chain dysfunctions position her to successfully treat both individuals with an active lifestyle and those who would like to become more active. The hypothalamus detects the amount of T4 circulating in the body and increases or decreases the amount of Thyroid Releasing Hormone (TRH) that is sent to the pituitary gland.
Hormones attached to proteins in the blood are in a constant state of flux meaning that they are constantly attaching and detaching. This is an autoimmune condition where the body attacks itself causing decreased T4 release. However, it is still fairly common that, when I mention and describe the Paleo Diet, patients change their expression. The Functional Medicine approach to nutrition means that each person has an adequate & functional nutritional status. Her grandfather was an MD surgeon, her uncle was an MD in family practice and her first cousin is an MD endocrinologist.
She is a member of the Florida Chiropractic Association and has additional training and certifications in Graston, Kinesiology sports taping and Postural assessment and rehabilitation. Arch Gen Psychiatry -- Early Coadministration of Clonazepam With Sertraline for Panic Disorder, July 2001, Goddard et al. The pituitary gland responds to the amount of TRH by releasing more or less Thyroid Stimulating Hormone (TSH).

This is a good thing since only free hormone (unattached) is available for biologic activity.
The process of this conversion is imperfect and T4 can be converted to either T3 or Reverse T3 (RT3).
Over time, this results in a resistance to T3 and hypothyroid symptoms due to this resistance. Physicians might consider that Morgellons and Bartonella are in some way intertwined.??Morgellons sufferers report an array of symptoms happening just under the skin, such as the emergence of fibers and filament clusters, specks, particles and sand shaped granules, yet physicians are unaware of this phenomena because they are not using enlargement devices.
Dr Colbert is a New York Times best selling author and has helped tens of thousands of patients to regain their health. She graduated Cum Laude from Palmer College of Chiropractic Florida Campus with her degree as a Chiropractic Physician. The problem here is that RT3 is not only ineffective but also blocks the T3 receptor and prevents T3 from having its effect. In the event that your anti-thyroid antibody levels are normal then you may simply need synthetic T4 supplementation (synthroid). I can now stand on my feet for an extended period of time and not have to sit down to get some relief.
An unaided visual exam using the naked eye is no longer appropriate to an emerging illness involving so many artifacts.
In her time there she worked with an enormous variety of patients, from healthy to very ill.
She believes that medical specialists can and should work together to create comprehensive health care for every patient.
This means that increased levels of TBG can result in hypothyroid symptoms since less free hormone is able to interact with the thyroid receptors. No one trusts the judgment of a mechanic who refuses to look under the hood of a car. A more thorough approach needs to be taken using equipment such as dermascopes and microscopes, as this is the only way to identify the microscopic fibers that are the defining symptom of Morgellons, and which separates it from all other diseases. It is her goal to help each patient create their own unique flowchart of health and to give them the tools they need to heal. Using a dermascope can also prevent misdiagnosing diseases that have some similar symptoms, such as Lyme (although some patients may have both). Colbert for his tutelage and his continued ministry using integrative medicine to heal patients. Microscopic enlargement needs to be at minimum 60x-200x in order to see the fibers clearly. As evidenced in the photos in our galleries, there is something clearly wrong with the skin of Morgellons sufferers. Most doctors currently believe that the fibers patients come to see them about are 'textile' in nature.
If you take a look at the galleries of fibers in urine, stool, blood, skin, and hair, you will see that these filaments are invading the body systemically and cannot possibly be textile. Click here to view other particles in the skin as well as other unidentified artifacts.?• ?Randy Wymore, Director of OSU-CHS Center for the Investigation of Morgellons Disease and Associate Professor of Pharmacology and Physiology had the fibers analyzed at the Tulsa police department's forensic laboratory. The Morgellons particles didn't match any of the 800 fibers on their database, nor the 85,000 known organic compounds. For those insisting the CDC study of Morgellons laid down the law for definitive answers about Morgellons, I'd suggest you listen to Doctor Randy Wymore speak more in depth about the study and its inherent flaws and bias. Many clinicians refer to this condition as delusional parasitosis or delusional infestation and consider the filaments to be introduced textile fibers.
In contrast, recent studies indicate that MD is a true somatic illness associated with tickborne infection, that the filaments are keratin and collagen in composition and that they result from proliferation and activation of keratinocytes and fibroblasts in the skin. Previously, spirochetes have been detected in the dermatological specimens from four MD patients, thus providing evidence of an infectious process. (2013) has revealed the presence of Borrelia in Morgellons lesions in everyone tested.
It is the subject of considerable debate within the medical profession and is often labeled as delusions of parasitosis or dermatitis artefacta.
This view is challenged by recent published scientific data put forward between 2011-2013 identifying the filaments found in MD as keratin and collagen based and furthermore associated with spirochetal infection.
The novel model of the dermopathy put forward by those authors is further described and, in particular, presented as a dermal manifestation of the multi-system disease complex borreliosis otherwise called Lyme disease. The requirements for a diagnosis of delusional disorder from a psychiatric perspective are clarified and the psychological or psychiatric co-morbidity that can be found with MD cases is presented. Management of the multisytem disease complex is discussed both in general and from a dermatological perspective. Despite evidence demonstrating that an infectious process is involved and that lesions are not self-inflicted, many medical practitioners continue to claim that this illness is delusional. We present relevant clinical observations combined with chemical and light microscopic studies of material collected from three patients with Morgellons disease. Our study demonstrates that Morgellons disease is not delusional and that skin lesions with unusual fibers are not self-inflicted or psychogenic.
Proliferative stages of bovine digital dermatitis demonstrate keratin filament formation in skin above the hooves in affected animals. The multifactorial etiology of digital dermatitis is not well understood, but spirochetes and other coinfecting microorganisms have been implicated in the pathogenesis of this veterinary illness. Morgellons disease is an emerging human dermopathy characterized by the presence of filamentous fibers of undetermined composition, both in lesions and subdermally. While the etiology of Morgellons disease is unknown, there is serological and clinical evidence linking this phenomenon to Lyme borreliosis and coinfecting tick-borne agents.
Although the microscopy of Morgellons filaments has been described in the medical literature, the structure and pathogenesis of these fibers is poorly understood.

In contrast, most microscopy of digital dermatitis has focused on associated pathogens and histology rather than the morphology of late-stage filamentous fibers. The most effective antibiotics have included tetracyclines (doxycycline, minocycline), macrolides (Zithromax, Biaxin), Septra DS, and quinolone drugs (Cipro, Levaquin, Avelox, and Factive). Often the skin lesions and associated symptoms resolve once the above antibiotics are used in a comprehensive treatment plan" ??Horowitz, Richard (2013-11-12). Why Can't I Get Better?: Solving the Mystery of Lyme and Chronic Disease (Kindle Locations 2662-2666). Still, 100% of the patients, that were felt to genuinely haveMorgellons Disease, have large microscopic-to small macroscopic fibersvisible under their outer layer of skin. These fibers are not associated withscabs or open lesions, nor are they under scarred tissue.
The idea thatMorgellons fibers are mere fuzz and lint, simply sticking to the lesions andscabs, is not possible based on the observations that were just described.These fibers are under "normal-appearing" areas of skin.
The photographs indicate that the particles are very active, and are growing "tendrils," fibers," "ruffles," protrusions," and are creating connections between themselves. These connecting "fibers" appear to be creating translucent "crystal clear" objects that give the appearance of "crystal fibers."                                                                              —Fungihomeworld.
5mar2010                 ?                   ?        Although Morgellons has no known "cure" at this time, we believe recognizing and identifying the disease gives a patient something to go on so they can start becoming proactive with their health.
Often these visits are out-of-pocket expenditures as patients escalate up the food chain to specialists not within their health plans, bankrupting themselves unnecessarily. Having a diagnosis will allow sufferers to make informed decisions about their next healthcare choices. There is no silver bullet when it comes to Morgellons.
A holistic approach working with diet and pH, plus supplements to rebuild the body's systems is one avenue towards proactive change and symptom reduction. Fibers and particles in various states of emergence from the skin. This mass exodus happens after coconut oil has been applied to my skin and usually takes 3-4 hours after application to see these kind of results.
Fibers under the skin can clearly be seen in these photos as well as in urine and stool, plus the lab doing DNA testing has noted that they are seeing fibers in stool samples. I truly do not understand how this could be misconstrued as a mental illness—and anti-depressants and anti-psychotics are not a fix.
This community is looking for a way to repair the health of the body.  A quick Google search revealed that only a quarter of the dermatologists in the United States even own a dermascope. Plus, a scope that only enlarges 10 or 15 times, is not going to be appropriate for diagnosis of Morgellons.
The fact that our doctors are supposedly experts and authorities, and considered the last word in the eyes of most of the public, yet are clearly not equipped to diagnose a new disease such as Morgellons, reflects poorly on the medical profession.?You have power to move the Morgellons cause along, if only you will participate. We need your support and input as health "authorities" to bring credibility to the phenomenon? happening.
If you think there are not enough people sick with this disease to warrant your time, think again and heed a call from those of us who are looking at the skin of our friends and families and are finding fibers in them. As of yet, this "healthy" population is asymptomatic, but we believe they are carrying the seeds of this disease in their systems. Imagine a world in which every patient going for a physical with their GP or dermatologist had 3 minutes devoted to examination of the skin with a scope—and what kind of data could be gathered from this!
That's the kind of world I would like to live in. One final note before I step off my soapbox is to reinforce the oath you took on becoming a doctor. DOP in patients records have led to loss of their legal rights, hospitalization against their will and in some cases children being removed from their parents.
Also, be cautious as to how you phase things as in "I'm having crawling sensations on my skin." instead of "I'm infested with bugs!" I'd refrain from using the term "Morgellons" until you sense you can trust your practitioner. Click the links to see extensive documentation of Morgellons fibers in Urine, Stool, Blood, Skin, Hair Above: Fiber is magnified 200x. At the time this was taken, my urine pH was very low (acidic) and I was having a hard time bringing it up to alkaline for two days. When I checked my skin I saw many more fibers then usual and many were still under the skin. I asked myself what would cause such fiber growth, and made the connection to an acidic system.
It it my personal wish to see physicians actually begin to use magnification so that they may understand the phenomena their patients are experiencing. Photo submitted courtesy of oddiyfuqoro NA will? Above: This particle is one of the classic forms I find being expelled from the body.
The Morgellons particles didn't match any of the 800 fibers on their database, nor the 85,000 known organic compounds.
For those insisting the CDC study of Morgellons laid down the law for definitive answers about Morgellons, I'd suggest you listen to Doctor Randy Wymore speak more in depth about the study and its inherent flaws and bias. Often the skin lesions and associated symptoms resolve once the above antibiotics are used in a comprehensive treatment plan" ??Horowitz, Richard (2013-11-12).

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