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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S.
Use of images for any purpose including but not limited to research, commercial, personal, or non-commercial use is prohibited without prior written consent. Vesicular stomatitis in a wild-caught juvenile Grauer’s gorilla (Gorilla beringei graueri).
Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions.

Gross lesions, histopathologic examination, transmission electron microscopy, and molecular screening confirmed human herpesvirus type 1 (HSV-1) as the etiologic agent. Use of trade names is for identification only and does not imply endorsement by any of the groups named above. B) Section of oral mucosa adjacent to a vesiculo-ulcerative lesion exhibits epithelial cell necrosis, cytoplasmic swelling, nuclear chromatin margination (sometimes with discrete Cowdry type A inclusions), and multinucleated syncytia typical of herpesviral cytopathic effects (hematoxylin and eosin stain). C) Electron micrograph of the same lesion demonstrates intranuclear, unenveloped virions ?100 nm in diameter that are budding through the nuclear membrane to form enveloped virions ?140 nm in diameter; morphologic features of both are compatible with a herpesvirus.

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