There is one clinical trial.
In this multicentric controlled study, we aims to evaluate effect of caffeine on mental performances during a sleep deprivation protocol. Genetic polymorphisms are considered as a covariable.
This study, under conditions of total sleep deprivation in the laboratory (40 hours of continuous awakening), examine the cross-influence of two polymorphisms (ADORA2A: rs5751876 and TNF-alpha: rs1800629) on the sensitivity to caffeine and on the degradation of attentional performances.
Description: Speed at the Psychomotor vigilance test testMeasure: Psychomotor vigilance test Speed Time: Change from Baseline Psychomotor vigilance test Speed at day 2 after 24 hours awaking
Description: Number of errors at executive performance testMeasure: Cognitive performance Time: Change from Baseline at day 2 after 25 hours awaking
Description: Power at the force-velocity testMeasure: Force -velocity Time: Change from Baseline at day 2 after 32 hours awaking