SNPMiner Trials by Shray Alag


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Report for Mutation P125A

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 The Efficacy and Safety of Endostar Combined With Taxane-based Regimens for HER-2-negative Metastatic Breast Cancer Patients

The purpose of the present study was to prospectively evaluate the efficacy and safety of endostar, a recombinant product of endostatin, combined with taxane-based regimens for HER-2 negative metastatic breast cancer (MBC) patients.

NCT02865304 Angiogenesis Breast Cancer Drug: endostar
MeSH:Breast Neoplasms
HPO:Breast carcinoma Neoplasm of the breast

Regarding breast cancer, in vivo studies showed that the combination of paclitaxel and P125A-endostatin inhibited mammary cancer growth, delayed the onset of multifocal mammary adenocarcinomas, decreased tumor angiogenesis, increased the survival of treated mice in the prevention model, and inhibited lung and lymph node metastasis in the intervention model. --- P125A ---

Primary Outcomes

Measure: overall response rate

Time: one year


HPO Nodes