SNPMiner Trials by Shray Alag

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SNPMiner SNPMiner Trials (Home Page)


Report for Mutation M11T

Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Consecutive, Case Control Study of Association Between Single Nucleotide Polymorphism of SP-D and Susceptibility and Prognosis of Infectious Keratitis

This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing

NCT04213313
Conditions
  1. Infectious Keratitis
Interventions
  1. Drug: Treatment of bacterial keratitis
  2. Drug: Treatment of fungal keratitis
  3. Drug: Treatment of viral keratitis
  4. Diagnostic Test: corneal scraping
  5. Other: Sequencing
MeSH:Communicable Diseases Infection Keratitis
HPO:Keratitis

Association Between SNP of SP-D and Susceptibility and Prognosis of Infectious Keratitis This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing Base type. --- Met11Thr ---

Primary Outcomes

Description: Base type of SNP(rs721917):(Met and Thr)

Measure: Base type

Time: before the treatment

Description: Genotype of SNP(rs721917):( Met /Met , Thr/Thr and Met/Thr)

Measure: Genotype

Time: before the treatment

Secondary Outcomes

Description: Grading of Keratitis: cornea:transparency ,edema,turbidity,perforation conjunctiva: hyperaemia blephar:inflammation

Measure: Grading of Keratitis

Time: before the treatment


HPO Nodes