There is one clinical trial.
Patient-ventilator asynchrony is an important clinical issue in mechanically ventilated patients. For patients with moderate to severe acute respiratory distress syndrome (ARDS), various types of patient ventilator asynchrony may lead to injury of the lung. For example, double cycling may lead to high tidal volume and pendelluft may result in transient overstretch of dependent lung region. In this project, the investigators will record and analyze various types of patient-ventilator asynchrony in ARDS patients and analyze the regional distribution of lung gas and determined their harmful effect via concomitant recording of EIT and transpulmonary pressure. The results may influence our ventilator management of ARDS patients.
Airway pressure and esophageal pressure will be measured using differential pressure transducers (P300D, Validyne Corp., Northridge, CA.). --- P300D ---
Description: Various types of patient ventilator asynchronyMeasure: Patient ventilator asynchrony Time: up to 1 hour following interruption of muscle relaxant
Description: Regional ventilation distribution by EIT in various types of patient ventilator asynchronyMeasure: Regional ventilation distribution by EIT Time: up to 1 hour following interruption of muscle relaxant
Description: duration of hospitalization and hospital mortalityMeasure: hospitalization day and final outcome Time: up to 3 months