SNPMiner Trials by Shray Alag

NCT00511368 (37) NCT00460382 (36) NCT04504071 (35) NCT03783286 (33) NCT04172597 (32) NCT02404233 (29) NCT00959894 (28) NCT00706147 (28) NCT00121017 (28) NCT01685801 (27) NCT04513626 (26) NCT01736761 (26) NCT04495348 (24) NCT02673398 (23) NCT02499978 (22) NCT01605084 (21) NCT04254705 (21) NCT02069834 (21) NCT00939770 (18) NCT01792570 (18) NCT01199939 (18) NCT00356616 (18) NCT02728258 (17) NCT02707601 (17) NCT02770508 (16) NCT00711009 (16) NCT00630864 (16) NCT00491556 (15) NCT04085315 (15) NCT02616029 (15) NCT00830804 (15) NCT04681820 (15) NCT01170962 (14) NCT00984152 (14) NCT03953898 (14) NCT00727597 (14) NCT03212274 (14) NCT01369199 (13) NCT00337467 (13) NCT00098293 (13) NCT01368497 (13) NCT02159599 (13) NCT00424814 (12) NCT04432454 (12) NCT02527096 (12) NCT01849003 (12) NCT03781063 (12) NCT03683524 (11) NCT01614457 (11) NCT00460746 (11) NCT00993148 (11) NCT03061331 (11) NCT02494882 (11) NCT03068312 (11) NCT04453436 (11) NCT01521338 (10) NCT02725567 (10) NCT01614470 (10) NCT01423812 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NCT02554591 (5) NCT01501604 (5) NCT02716116 (5) NCT01136460 (5) NCT00187655 (5) NCT00350272 (5) NCT00837135 (5) NCT03202862 (5) NCT01707199 (5) NCT03839342 (5) NCT01323010 (4) NCT02248324 (4) NCT01698905 (4) NCT01737359 (4) NCT01306045 (4) NCT02804100 (4) NCT01456676 (4) NCT00588172 (4) NCT03434418 (4) NCT03593993 (4) NCT01804140 (4) NCT02882308 (4) NCT03497767 (4) NCT04106024 (4) NCT02716311 (4) NCT04405674 (4) NCT03599518 (4) NCT01675778 (4) NCT01604122 (4) NCT01297777 (4) NCT04519970 (4) NCT00705679 (4) NCT04147351 (4) NCT04129502 (4) NCT03976856 (4) NCT02335944 (4) NCT04625647 (4) NCT03948763 (4) NCT03255083 (4) NCT04002830 (4) NCT02635815 (4) NCT03066206 (4) NCT01331642 (4) NCT00557245 (4) NCT01922583 (4) NCT02893332 (4) NCT03592888 (4) NCT02257424 (4) NCT03874858 (4) NCT00017732 (4) NCT00187720 (4) NCT02593539 (4) NCT01185587 (4) NCT04439292 (4) NCT03884348 (4) NCT01309243 (4) NCT03209063 (4) NCT04160546 (4) NCT03292302 (4) NCT02418234 (4) NCT02535338 (3) NCT02192697 (3) NCT03410043 (3) NCT03845296 (3) NCT02914990 (3) NCT02113813 (3) NCT01532011 (3) NCT04340388 (3) NCT00962533 (3) NCT03856411 (3) NCT04049266 (3) NCT02973763 (3) NCT02926092 (3) NCT00271973 (3) NCT04256941 (3) NCT03812809 (3) NCT02954523 (3) NCT01784068 (3) NCT03446417 (3) NCT02841579 (3) NCT02025114 (3) NCT01288521 (3) NCT01385683 (3) NCT02279004 (3) NCT00998582 (3) NCT03111901 (3) NCT01352715 (3) NCT01619774 (3) NCT01045369 (3) NCT02246998 (3) NCT03969823 (3) NCT00895596 (3) NCT02398929 (3) NCT00724711 (3) NCT04029350 (3) NCT03737994 (3) NCT01443806 (3) NCT02629822 (3) NCT03463525 (3) NCT00710112 (3) NCT03623750 (3) NCT04283955 (3) NCT02743923 (3) NCT01016106 (3) NCT01259089 (3) NCT03971474 (3) NCT02917993 (3) NCT02368990 (3) NCT00279110 (3) NCT02485652 (3) NCT00312169 (3) NCT04541407 (3) NCT02769286 (3) NCT00747487 (3) NCT04267913 (3) NCT01429597 (3) NCT04023617 (3) NCT03790228 (3) NCT01759888 (3) NCT04429152 (3) NCT01810718 (3) NCT02725632 (3) NCT01090011 (3) NCT04544111 (3) NCT02926768 (3) NCT02981108 (3) NCT02459743 (3) NCT00654823 (3) NCT01037127 (3) NCT04439305 (3) NCT01028222 (3) NCT01542411 (3) NCT01031446 (3) NCT02726269 (3) NCT01892644 (3) NCT03260491 (3) NCT01802632 (3) NCT02720094 (3) NCT02630186 (3) NCT01627132 (3) NCT02690675 (3) NCT01013506 (3) NCT04252339 (3) NCT02496663 (3) NCT03386955 (3) NCT03394118 (3) NCT04212702 (3) NCT01754025 (3) NCT01160276 (3) NCT00121979 (3) NCT03228277 (3) NCT04351555 (3) NCT01243346 (3) NCT04510415 (3) NCT02796274 (3) NCT02774005 (3) NCT02064491 (3) NCT04233021 (3) NCT03799601 (3) NCT00260260 (3) NCT02094261 (3) NCT04245085 (3) NCT03058094 (3) NCT01282151 (3) NCT02520778 (3) NCT03161808 (3) NCT04181060 (3) NCT01342679 (3) NCT01443273 (3) NCT01593254 (3) NCT04433481 (3) NCT02529995 (3) NCT03502850 (3) NCT02771314 (3) NCT03823807 (3) NCT03270527 (3) NCT02688881 (3) NCT01005602 (3) NCT02442349 (3) NCT02684591 (2) NCT02282267 (2) NCT03381430 (2) NCT02178397 (2) NCT03608215 (2) NCT02603107 (2) NCT03370770 (2) NCT03322696 (2) NCT03333343 (2) NCT00525473 (2) NCT03127449 (2) NCT01781026 (2) NCT02503722 (2) NCT00975871 (2) NCT03964233 (2) NCT03388099 (2) NCT02317016 (2) NCT03845270 (2) NCT03519958 (2) NCT03918304 (2) NCT02151721 (2) NCT02777658 (2) NCT01016444 (2) NCT02971501 (2) NCT03101254 (2) NCT03178617 (2) NCT01774721 (2) NCT03574753 (2) NCT01357655 (2) NCT01766713 (2) NCT02097225 (2) NCT00658164 (2) NCT03622593 (2) NCT02571036 (2) NCT00969137 (2) NCT00834665 (2) NCT02026011 (2) NCT03622580 (2) NCT03543683 (2) NCT01143493 (2) NCT03671538 (2) NCT04028778 (2) NCT00324961 (2) NCT01915576 (2) NCT02157883 (2) NCT01387022 (2) NCT03864042 (2) NCT03235245 (2) NCT03469960 (2) NCT02795884 (2) NCT04687241 (2) NCT00005541 (2) NCT01242813 (2) NCT03960645 (2) NCT00643058 (2) NCT03443336 (2) NCT02992860 (2) NCT02281760 (2) NCT02201602 (2) NCT04310007 (2) NCT04309019 (2) NCT03720665 (2) NCT00909532 (2) NCT00411944 (2) NCT01604681 (2) NCT01245062 (2) NCT00270231 (2) NCT03256136 (2) NCT03973918 (2) NCT00302692 (2) NCT00125281 (2) NCT02163733 (2) NCT02110407 (2) NCT00475176 (2) NCT03196882 (2) NCT01572818 (2) NCT02556333 (2) NCT04268550 (2) NCT02433717 (2) NCT03428126 (2) NCT01153763 (2) NCT02609776 (2) NCT01420211 (2) NCT03556176 (2) NCT03872440 (2) NCT01405079 (2) NCT03382795 (2) NCT02991950 (2) NCT00013598 (2) NCT03455764 (2) NCT02422628 (2) NCT03831932 (2) NCT03766490 (2) NCT02580474 (2) NCT00499577 (2) NCT02444884 (2) NCT01775943 (2) NCT03544814 (2) NCT01310036 (2) NCT01027663 (2) NCT01928160 (2) NCT01244438 (2) NCT00007150 (2) NCT04462081 (2) NCT02297425 (2) NCT02086071 (2) NCT01050400 (2) NCT03060590 (2) NCT01819428 (2) NCT02709668 (2) NCT02411448 (2) NCT03878719 (2) NCT04622072 (2) NCT04479306 (2) NCT03377023 (2) NCT01378026 (2) NCT03239145 (2) NCT04511533 (2) NCT00226551 (2) NCT02191891 (2) NCT04586270 (2) NCT04669535 (2) NCT04545710 (2) NCT02120222 (2) NCT02738593 (2) NCT00831272 (2) NCT04469543 (2) NCT00573495 (2) NCT04158544 (2) NCT00904150 (2) NCT02110056 (2) NCT02856893 (2) NCT02110043 (2) NCT02182986 (2) NCT04179890 (2) NCT00063232 (2) NCT02197234 (2) NCT03121235 (2) NCT01532089 (2) NCT03887169 (2) NCT02268864 (2) NCT01963845 (2) NCT00866736 (2) NCT03991013 (2) NCT02500927 (2) NCT04657991 (2) NCT02228382 (2) NCT02689570 (2) NCT01513785 (2) NCT02463435 (2) NCT03351361 (2) NCT04527549 (2) NCT03424759 (2) NCT02197247 (2) NCT02321046 (2) NCT04272034 (2) NCT04646824 (2) NCT04027647 (2) NCT02364609 (2) NCT02759835 (2) NCT04349865 (2) NCT00068159 (2) NCT00418015 (2) NCT04310397 (2) NCT03088176 (2) NCT03867175 (2) NCT00339209 (2) NCT00011258 (2) NCT01288430 (2) NCT01616199 (2) NCT03603262 (2) NCT03071705 (2) NCT00969930 (2) NCT00772408 (2) NCT02743468 (2) NCT00277342 (2) NCT04248829 (2) NCT01767454 (2) NCT00933127 (2) NCT03317873 (2) NCT03392246 (2) NCT01909453 (2) NCT03523104 (2) NCT00085917 (2) NCT02507921 (2) NCT03781752 (2) NCT03828422 (2) NCT02193282 (2) NCT03195452 (2) NCT04657289 (2) NCT02294487 (2) NCT01325441 (2) NCT02511106 (2) NCT02997501 (2) NCT04184921 (2) NCT00625092 (2) NCT01657786 (2) NCT01415011 (2) NCT02629523 (2) NCT01718847 (2) NCT02818023 (2) NCT00577707 (2) NCT01943422 (2) NCT00116636 (2) NCT04429542 (2) NCT01841463 (2) NCT03865511 (2) NCT03205267 (2) NCT01218477 (2) NCT02881320 (2) NCT01897480 (2) NCT02810990 (2) NCT04189757 (2) NCT01951001 (2) NCT04254939 (2) NCT03207867 (2) NCT00780949 (2) NCT03355768 (2) NCT00817089 (2) NCT02143466 (2) NCT04499053 (2) NCT01907776 (2) NCT00909727 (2) NCT01562028 (2) NCT03737253 (2) NCT00441974 (2) NCT02155465 (2) NCT04586335 (2) NCT00661999 (2) NCT02705339 (2) NCT04006340 (2) NCT04553887 (2) NCT04645225 (2) NCT03852290 (2) NCT02183922 (2) NCT03970239 (2) NCT00294372 (2) NCT03250676 (2) NCT03792074 (2) NCT00671892 (2) NCT00689182 (2) NCT00106379 (2) NCT01947023 (2) NCT00509652 (2) NCT03683251 (2) NCT02039986 (2) NCT03515837 (2) NCT04081688 (2) NCT03190005 (2) NCT01584648 (2) NCT02292654 (2) NCT03992456 (2) NCT03133546 (2) NCT01485809 (2) NCT01266967 (2) NCT04644315 (2) NCT02909712 (2) NCT00062764 (2) NCT01776684 (2) NCT03042221 (2) NCT01940809 (2) NCT04675008 (2) NCT01161537 (2) NCT01154816 (2) NCT01175759 (2) NCT01199731 (2) NCT02788058 (2) NCT03130452 (2) NCT04687423 (2) NCT01772732 (2) NCT02631447 (2) NCT02525692 (2) NCT02526537 (2) NCT03513666 (2) NCT02027961 (2) NCT03106779 (2) NCT04106544 (2) NCT04258943 (2) NCT00165984 (2) NCT00977470 (2) NCT02092974 (2) NCT03975231 (2) NCT03586453 (2) NCT01998295 (2) NCT02021305 (2) NCT03135197 (2) NCT00432016 (2) NCT04636437 (2) NCT03004625 (2) NCT03851445 (2) NCT04031898 (2) NCT04201418 (2) NCT01911507 (2) NCT03539224 (2) NCT01978236 (2) NCT00866177 (2) NCT00320879 (2) NCT00044304 (2) NCT01999179 (2) NCT00977730 (2) NCT02491775 (2) NCT00212147 (2) NCT02040064 (2) NCT00489385 (2) NCT01713023 (2) NCT04122729 (2) NCT03994393 (2) NCT02438722 (2) NCT02762448 (2) NCT00071903 (2) NCT00626223 (2) NCT01193829 (2) NCT03239340 (2) NCT02991274 (2) NCT02811354 (2) NCT03416530 (2) NCT02522988 (2) 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NCT03678506 (1) NCT02146365 (1) NCT04310943 (1) NCT02619955 (1) NCT02934139 (1) NCT00400387 (1) NCT00375219 (1) NCT00149305 (1) NCT03520946 (1) NCT02787447 (1) NCT04501614 (1) NCT03166631 (1) NCT04213313 (1) NCT02078531 (1) NCT02349048 (1) NCT02981784 (1) NCT04636593 (1) NCT01647711 (1) NCT03231722 (1) NCT03576937 (1) NCT04412070 (1) NCT00554866 (1) NCT03151161 (1) NCT01817166 (1) NCT02220855 (1) NCT02512627 (1) NCT04591197 (1) NCT03402048 (1) NCT04500704 (1) NCT02323724 (1) NCT01166126 (1) NCT03029858 (1) NCT04317599 (1) NCT00300573 (1) NCT00809211 (1) NCT01393730 (1) NCT02318368 (1) NCT02228369 (1) NCT04500717 (1) NCT01074398 (1) NCT03134131 (1) NCT02455167 (1) NCT01004497 (1) NCT02073279 (1) NCT02117817 (1) NCT00323687 (1) NCT01605981 (1) NCT01371955 (1) NCT04147767 (1) NCT04144257 (1) NCT03490123 (1) NCT04423185 (1) NCT02625337 (1) NCT03567629 (1) NCT03360929 (1) NCT00109278 (1) NCT04108156 (1) NCT02132598 (1) NCT00542451 (1) NCT01587573 (1) NCT00868465 (1) NCT01494402 (1) 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SNPMiner SNPMiner Trials (Home Page)


Report for Clinical Trial NCT04108156

Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene

A Phase III, Multicenter, Randomized, Visual Assessor-Masked, Active-comparator Study of the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Patients With Diabetic Macular Edema (Pagoda)

This study will evaluate the efficacy, safety, and pharmacokinetics of the Port Delivery System with Ranibizumab (PDS) in Participants with Diabetic Macular Edema (DME) when treated every 24 weeks (Q24W) compared with intravitreal ranibizumab 0.5 mg every 4 weeks (Q4W).

NCT04108156 Diabetic Macular Edema
MeSH:Macular Edema Edema
HPO:Anasarca Cystoid macular edema Edema Macular edema

2 Interventions

Name: PDS Implant Pre-Filled with 100 mg/mL Ranibizumab

Description: Will be administered as per the schedule described in individual arm.
Type: Drug
Group Labels: 1

PDS Arm

Name: Intravitreal Ranibizumab 0.5 mg Injection

Description: Will be administered as per the schedule described in individual arm.
Type: Drug
Group Labels: 1

Intravitreal Arm


Primary Outcomes

Description: BCVA = Best-Corrected Visual Acuity ETDRS = Early Treatment Diabetic Retinopathy Study A vision score of 20/20 vision is considered normal. A score of 20/200 is considered being legally blind.

Measure: Change in BCVA score from baseline averaged over Weeks 60 and 64 as measured using the ETDRS chart in the efficacy population

Time: Baseline to Week 64

Secondary Outcomes

Description: ETDRS-DRSS = ETDRS Diabetic Retinopathy Severity Scale

Measure: Change in BCVA score from baseline averaged over Weeks 60 and 64 as measured with use of the ETDRS chart in the per protocol population

Time: Baseline to Week 64

Measure: Percentage of participants with a ≥2-step improvement from baseline on the ETDRS-DRSS at Week 64 in the efficacy population

Time: Baseline to Week 64

Measure: Percentage of participants with a ≥2-step improvement from baseline on the ETDRS-DRSS at Week 64 in the per protocol population

Time: Baseline to Week 64

Measure: Change from baseline in BCVA as measured on the ETDRS chart over time

Time: Baseline up to Week 120

Measure: Percentage of participants who lose <10, and <5 letters in BCVA from baseline over time

Time: Baseline up to Week 120

Measure: Percentage of participants who gain ≥15, ≥10, ≥5, ≥0 letters in BCVA from baseline over time

Time: Baseline up to Week 120

Measure: Percentage of participants with a BCVA Snellen equivalent of 20/40 or better over time

Time: Baseline up to Week 120

Measure: Percentage of participants with a BCVA Snellen equivalent of 20/200 or worse over time

Time: Baseline up to Week 120

Measure: Percentage of participants with a ≥3-step improvement from baseline on the ETDRS-DRSS at Week 64

Time: Baseline to Week 64

Measure: Percentage of participants with a ≥2-step improvement from baseline on the ETDRS-DRSS over time

Time: Baseline up to Week 120

Measure: Percentage of participants with a ≥3-step improvement from baseline on the ETDRS-DRSS over time

Time: Baseline up to Week 120

Measure: Time to ≥2-step worsening from baseline on the ETDRS-DRSS

Time: Baseline up to Week 120

Measure: Time to ≥3-step worsening from baseline on the ETDRS-DRSS

Time: Baseline up to Week 120

Measure: Change from baseline in ETDRS-DRSS score over time

Time: Baseline up to Week 120

Description: CST = central subfield thickness SD-OCT = spectral domain optical coherence tomography

Measure: Change from baseline in CST as measured on SD-OCT at Week 64

Time: Baseline to Week 64

Measure: Change from baseline in CST as measured on SD-OCT over time

Time: Baseline up to Week 120

Measure: Change from baseline in total macular volume as measured on SD-OCT over time

Time: Baseline up to Week 120

Description: DME = diabetic macular edema

Measure: Percentage of participants with DME (defined as CST ≥325 μm on SD-OCT) over time

Time: Baseline up to Week 120

Description: PDR = proliferative diabetic retinopathy

Measure: Time to PDR (defined as a score ≥60 on the ETDRS-DRSS)

Time: Baseline up to Week 120

Measure: Percentage of participants who do not undergo supplemental treatment with intravitreal ranibizumab within each refill-exchange interval

Time: Baseline up to Week 120

Measure: Percentage of participants who report preferring PDS treatment compared with intravitreal ranibizumab treatment, as measured by the PDS Patient Preference Questionnaire (PPPQ) at Week 64 among participants in the PDS arm efficacy population

Time: Baseline to Week 64

Measure: Percentage of participants who report preferring PDS treatment compared with intravitreal ranibizumab treatment, as measured by the PDS Patient Preference Questionnaire (PPPQ) at Week 64 among participants in per protocol population

Time: Baseline to Week 64

Description: Participants in in a subset of patients with bilateral disease who are simultaneously receiving ranibizumab via study eye PDS implant and fellow eye intravitreal injection

Measure: Percentage of participants who report preferring PDS treatment compared with intravitreal ranibizumab treatment, as measured by the PDS Patient Preference Questionnaire (PPPQ) at Week 64

Time: Baseline to Week 64

Measure: Incidence and severity of ocular adverse events

Time: Baseline to Week 120

Measure: Incidence and severity of non-ocular adverse events

Time: Baseline up to Week 120

Measure: Incidence, severity, and duration of adverse events of special interest

Time: Baseline up to Week 120

Measure: Incidence, severity, and duration of PDS-associated adverse events of special interest during the postoperative period (up to 37 days after initial implantation) and follow-up period (>37 days after implantation surgery)

Time: Baseline up to Week 120

Measure: Serum concentration of ranibizumab observed over time

Time: Baseline up to Week 120

Measure: PK parameter value area under the concentration- time curve over 24 weeks (AUC24W)

Time: Baseline to Week 24

Measure: Pharmacokinetic (PK) parameter maximum serum concentration (Cmax)

Time: Baseline up to Week 120

Measure: PK Parameter minimum serum concentration (Cmin)

Time: Baseline up to Week 120

Measure: PK parameter half-life (t1/2) after PDS implant insertion

Time: Baseline up to Week 120

Measure: Prevalence of anti-drug antibodies (ADAs) at baseline and incidence of ADAs during the study

Time: Baseline up to Week 120

Purpose: Treatment

Allocation: Randomized

Parallel Assignment


There is one SNP

SNPs


1 Q24W

This Study Will Evaluate the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Participants With Diabetic Macular Edema Compared With Intravitreal Ranibizumab This study will evaluate the efficacy, safety, and pharmacokinetics of the Port Delivery System with Ranibizumab (PDS) in Participants with Diabetic Macular Edema (DME) when treated every 24 weeks (Q24W) compared with intravitreal ranibizumab 0.5 mg every 4 weeks (Q4W). --- Q24W ---



HPO Nodes


HPO:
HP:0000969: Edema
Genes 607
TLL1 PSMB4 SOX18 PIGN RPS7 SAMHD1 UBR1 MAGEL2 UBR1 HGD FN1 IGH PIEZO1 FAT4 MAGEL2 COL1A1 KRT13 INPPL1 MPI GTF2IRD1 CALCRL EPB41 CTRC BMPR1A WNT7A RASA2 KIF11 NAGA EGFR OSGEP PTPN22 LAMA3 RPS15A BMP2 AKT1 GJC2 NLRP3 CFTR CDK5 HPGD OCA2 PDSS2 VSX1 PRPF8 PAX2 BTNL2 PIK3CD FSHR ASS1 HADHA TCF4 ANTXR1 WDR35 SNX14 PRSS1 HLA-DPA1 GATA6 KRT2 CPT2 DYNC2I1 RIT1 NDN BUB1B IL2RA ARHGDIA GNPTAB CLIP2 CHEK2 IL6 CYBC1 SCN4A IDH3A COL1A2 ZEB1 NEB PKLR CAMTA1 KCTD1 KLHL41 LBR DIS3L2 GPC6 TREX1 ABCC6 PMM2 NRAS RB1 FIG4 COL11A1 ELN TRAF3 PTEN RLBP1 SMCHD1 MYD88 MYH6 AGGF1 CLCNKB ABCA3 PIGA TSC1 HLA-DPB1 KCNN4 RP9 ACTB HFE PEX2 HPGD PTPN2 RPL27 PTPN22 SLC22A4 MAPRE2 CD28 RRAS2 COQ8B CCN6 EPHB4 ACTN4 RPL11 NOD2 FLNB RANBP2 FOXC2 KRAS CTLA4 CLCNKA SPTB ADAMTS3 SLC40A1 NRL PRKCD FGB COL5A1 MRPS22 CD46 SMAD4 BCL2 KNSTRN GLA GJC2 RPL15 ADA2 DYNC2I2 TNFRSF1B CBL VPS51 FAT4 IL7R MAP2K2 FECH NLRP3 PTPN2 GBA STX11 F12 NEK1 ZNHIT3 PTH1R RNF13 TPRKB RPL35 SLC26A2 FAS SLC25A4 PRPH2 GSN CD247 SLC35C1 PRTN3 TAPT1 NAGA NOD2 SLC4A1 KLHL40 RAG1 F8 ATP1A2 RRAS IL2RA SNRPN PTPN11 DOK7 DDR2 GATA2 ANKRD55 TMEM260 CCBE1 USP8 KMT2A APOE SOS2 ADAMTS3 LACC1 KAT6A ACAT1 CASP10 DCHS1 KIF20A RMRP KRAS OTC GPR101 C4A RPL18 MECOM KPTN LBR SNRPN FRMD4A STAT4 ABCC9 KIF1A MRAS COL2A1 MEFV FGFR3 DNMT1 CCBE1 KCNQ2 TP53 ADA MFRP TBX20 FIG4 PSMB9 SERPING1 KCTD1 CDC42 PRF1 TICAM1 AHCY ACAD9 BCL6 LAMA2 PADI4 GATA4 SUMF1 GUSB GLA CAMTA1 DHCR7 MMACHC MIF GUSB HADHB GRIP1 RYR1 SCARB2 CHRNG GBA SPP1 CITED2 PTPRO OCA2 MYBPC3 MKKS HLA-DRB1 CEP57 CTLA4 RAD21 IL2RB FRMD4A BCKDHB HMGCL FGG ALPK3 PTPN22 DHDDS SFTPC UROS LEMD3 ODC1 DNASE1L3 RASGRP1 PLAA IL10 FLT4 SOS1 RPS19 IL12A-AS1 RPL26 PHGDH TGM1 ACTG1 PIEZO1 PIK3CA RDH5 ZNHIT3 LPIN2 DBT FRG1 NDUFS4 TSC2 RANBP2 ANAPC1 GATA2 CBL ARL3 COL8A2 IL12A TEK NKX2-5 CD244 POLG2 FLT4 NIPBL POMP KIAA1109 RPS28 NDN SLCO2A1 LYZ SMCHD1 MRPS16 DYNC2H1 CHD7 ACP5 PTPN22 KIF7 CFI OCA2 B2M SFTPB GRHL2 CPN1 TNNT2 PLVAP NLRP3 BRAF SOX18 ACTC1 IFT80 FGFR3 ALG14 ZEB1 FGA HBA2 RPS26 GATA1 EBP CSGALNACT1 PMM2 RPS17 APC2 TRIP11 LMX1B GBA ENG PLCG2 SLC29A3 VEGFC NDN TNFRSF1A PSPH IL2RB POMGNT1 RAG2 TP53 NSD1 XPNPEP2 KIT SHANK3 BUB1 STAT4 IGSF3 PDE6G TNFRSF11B PRSS2 TBL2 IL10 FLNC TNFRSF1B SPTA1 KIAA0586 CDH11 RFC2 SLC40A1 LAMC2 NPHS2 FECH PLAA SGPL1 RRM2B LIMK1 DSP PEX5 SLC26A2 IL6 TWNK COQ2 UNC93B1 RIT1 PTH1R MYO1E CDC42 RPS10 GATC CCND1 ALG8 STAT4 LTBP4 ASL VAC14 KLF1 MST1 ERCC5 NUP107 BRAF HNRNPK FASLG TUBB NOS3 GATB RIN2 RAF1 COG6 MAP2K1 CTSA ASAH1 PRKAG2 HAVCR2 HLA-DRB1 CFH LAMB2 ANKRD55 OVOL2 COL1A1 TALDO1 NEU1 VEGFC TRIP11 NPHS1 IL23R SPINK1 CHRNA1 CPS1 TNNI3 DNMT3B NEK9 SPINK5 PTPN11 GLE1 ACAD9 GBE1 POLG SERPING1 LPIN2 NEU1 ACTA1 PLD1 ADARB1 SLC25A13 DYSF SLC35D1 DCLRE1C IBA57 KRAS TLR4 RPL31 A2ML1 CDAN1 FGA RP1L1 MEFV NAXE IKBKG OTULIN F8 PTPN14 BSND NRAS RPL5 RPS27 ABCC9 RPS24 RPL35A FAS COL2A1 WDR35 PTEN TREX1 ASAH1 INPPL1 GTF2I TNFRSF1A MAGEL2 GBA MEFV SHANK3 STAT4 CACNA1A CCDC88A LAMB3 SMS APOA1 IL1RN IRAK1 REEP6 RYR1 FAT4 NDUFB10 RECQL4 ALG1 TBX20 SETD5 CCR1 RELN KIF11 UBAC2 RIN2 HFE MED12L CD247 HNRNPK AIP BCKDHA WDR35 CARS2 IFT172 RBM8A FAS SMC1A MAP2K1 SETD2 CTLA4 SOX18 ERBB3 OCRL ANTXR2 QRSL1 ANKH HBA1 CHRND SMC3 DUX4 ITK ERAP1 PKLR GATA1 ALB CD28 TLR3 TSR2 SNRPN TET2 BMPER LYST MYPN ATN1 SLC25A13 GYPC HDAC8 TBK1 PRRT2 NR2E3 GNAQ KIAA1549 KLRC4 BUB3 FOXC2 ACADM PLCE1 TRIP13 LZTR1 SCN1A HLA-DRB1 FOXG1 COL2A1 COL8A2 LIG4 ADAMTS2 ALG12 ATP7B CD55 HLA-DRB1 PRPF31 RPS29 TLL1 NAXD HELLPAR LMOD3 TMPRSS15 ARHGEF18 TCF4 ALG9 GPR35 BAZ1B VHL CIITA NAGA RHO IL2RG SLC17A5 AIP COL5A2 ABCC9 HLA-A PDSS2 NR1H4 CYTB SERPING1 NFKBIL1 BTNL2 HLA-B PRKAR1A MVK
Protein Mutations 0
SNP 0