SNPMiner Trials by Shray Alag

NCT00511368 (37) NCT00460382 (36) NCT04504071 (35) NCT03783286 (33) NCT04172597 (32) NCT02404233 (29) NCT00959894 (28) NCT00706147 (28) NCT00121017 (28) NCT01685801 (27) NCT04513626 (26) NCT01736761 (26) NCT04495348 (24) NCT02673398 (23) NCT02499978 (22) NCT01605084 (21) NCT04254705 (21) NCT02069834 (21) NCT00939770 (18) NCT01792570 (18) NCT01199939 (18) NCT00356616 (18) NCT02728258 (17) NCT02707601 (17) NCT02770508 (16) NCT00711009 (16) NCT00630864 (16) NCT00491556 (15) NCT04085315 (15) NCT02616029 (15) NCT00830804 (15) NCT01170962 (14) NCT00984152 (14) NCT03953898 (14) NCT00727597 (14) NCT03212274 (14) NCT00337467 (13) NCT00098293 (13) NCT02159599 (13) NCT00424814 (12) NCT04432454 (12) NCT02527096 (12) NCT01849003 (12) NCT03781063 (12) NCT03683524 (11) NCT01614457 (11) NCT00460746 (11) NCT00993148 (11) NCT03061331 (11) NCT02494882 (11) NCT03068312 (11) NCT04453436 (11) NCT01521338 (10) NCT01614470 (10) NCT01423812 (10) NCT00358917 (10) NCT04415268 (10) NCT00511381 (10) NCT03911713 (9) NCT02742519 (9) NCT02725567 (9) NCT03045523 (9) NCT00438152 (9) NCT01102972 (9) NCT02971839 (9) NCT00740064 (9) NCT02605954 (9) NCT00379405 (9) NCT01562847 (9) NCT02616783 (9) NCT04272242 (9) NCT02445053 (9) NCT00242840 (9) NCT02724527 (9) NCT04209465 (9) NCT04585737 (8) NCT02082977 (8) NCT00112775 (8) NCT00383318 (8) NCT03659214 (8) NCT03631732 (8) NCT00118898 (8) NCT01888562 (8) NCT02633189 (8) NCT03565692 (8) NCT03843775 (8) NCT01161576 (8) NCT02167165 (8) NCT00344461 (8) NCT04519398 (7) NCT02154490 (7) NCT03232892 (7) NCT00650832 (7) NCT04549025 (7) NCT00440947 (7) NCT02784639 (7) NCT03572140 (6) NCT01237444 (6) NCT00532168 (6) NCT01102569 (6) NCT04424368 (6) NCT01414985 (6) NCT00525733 (6) NCT02308332 (6) NCT01487265 (6) NCT00049933 (5) NCT02389920 (5) NCT03351699 (5) NCT04197934 (5) NCT02272998 (5) NCT00122590 (5) NCT04204330 (5) NCT02450591 (5) NCT01173029 (5) NCT02675829 (5) NCT02858921 (5) NCT01914484 (5) NCT00187733 (5) NCT02554591 (5) NCT01501604 (5) NCT02716116 (5) NCT01136460 (5) NCT00187655 (5) NCT00350272 (5) NCT00837135 (5) NCT03202862 (5) NCT01707199 (5) NCT03839342 (5) NCT01323010 (4) NCT02248324 (4) NCT01698905 (4) NCT01737359 (4) NCT01306045 (4) NCT02804100 (4) NCT01456676 (4) NCT00588172 (4) NCT03434418 (4) NCT03593993 (4) NCT01804140 (4) NCT02882308 (4) NCT03497767 (4) NCT04106024 (4) NCT02716311 (4) NCT04405674 (4) NCT03599518 (4) NCT01675778 (4) NCT01604122 (4) NCT01297777 (4) NCT04519970 (4) NCT00705679 (4) NCT04147351 (4) NCT04129502 (4) NCT03976856 (4) NCT02335944 (4) NCT03948763 (4) NCT03255083 (4) NCT04002830 (4) NCT02635815 (4) NCT03066206 (4) NCT01331642 (4) NCT00557245 (4) NCT01922583 (4) NCT02893332 (4) NCT03592888 (4) NCT02257424 (4) NCT03874858 (4) NCT00017732 (4) NCT00187720 (4) NCT02593539 (4) NCT01185587 (4) NCT04439292 (4) NCT03884348 (4) NCT01309243 (4) NCT03209063 (4) NCT04160546 (4) NCT03292302 (4) NCT02418234 (4) NCT02535338 (3) NCT02192697 (3) NCT03410043 (3) NCT03845296 (3) NCT02914990 (3) NCT02113813 (3) NCT01532011 (3) NCT04340388 (3) NCT00962533 (3) NCT03856411 (3) NCT04049266 (3) NCT02973763 (3) NCT02926092 (3) NCT00271973 (3) NCT04256941 (3) NCT03812809 (3) NCT02954523 (3) NCT01784068 (3) NCT03446417 (3) NCT02841579 (3) NCT02025114 (3) NCT01288521 (3) NCT01385683 (3) NCT02279004 (3) NCT00998582 (3) NCT03111901 (3) NCT01352715 (3) NCT01619774 (3) NCT01045369 (3) NCT02246998 (3) NCT03969823 (3) NCT00895596 (3) NCT02398929 (3) NCT00724711 (3) NCT04029350 (3) NCT03737994 (3) NCT01443806 (3) NCT02629822 (3) NCT03463525 (3) NCT00710112 (3) NCT03623750 (3) NCT04283955 (3) NCT02743923 (3) NCT01016106 (3) NCT01259089 (3) NCT03971474 (3) NCT02917993 (3) NCT02368990 (3) NCT00279110 (3) NCT02485652 (3) NCT00312169 (3) NCT04541407 (3) NCT02769286 (3) NCT00747487 (3) NCT04267913 (3) NCT01429597 (3) NCT04023617 (3) NCT03790228 (3) NCT01759888 (3) NCT04429152 (3) NCT01810718 (3) NCT02725632 (3) NCT01090011 (3) NCT04544111 (3) NCT02926768 (3) NCT02981108 (3) NCT02459743 (3) NCT00654823 (3) NCT01037127 (3) NCT04439305 (3) NCT01028222 (3) NCT01542411 (3) NCT01031446 (3) NCT02726269 (3) NCT01892644 (3) NCT03260491 (3) NCT01802632 (3) NCT02720094 (3) NCT02630186 (3) NCT01627132 (3) NCT02690675 (3) NCT01013506 (3) NCT04252339 (3) NCT02496663 (3) NCT03386955 (3) NCT03394118 (3) NCT04212702 (3) NCT01754025 (3) NCT01160276 (3) NCT00121979 (3) NCT03228277 (3) NCT04351555 (3) NCT01243346 (3) NCT04510415 (3) NCT02796274 (3) NCT02774005 (3) NCT02064491 (3) NCT04233021 (3) NCT03799601 (3) NCT00260260 (3) NCT02094261 (3) NCT04245085 (3) NCT01282151 (3) NCT03058094 (3) NCT02520778 (3) NCT03161808 (3) NCT04181060 (3) NCT01342679 (3) NCT01443273 (3) NCT01593254 (3) NCT04433481 (3) NCT02529995 (3) NCT03502850 (3) NCT02771314 (3) NCT03823807 (3) NCT03270527 (3) NCT02688881 (3) NCT01005602 (3) NCT02442349 (3) NCT02282267 (2) NCT02684591 (2) NCT03381430 (2) NCT02178397 (2) NCT03608215 (2) NCT02603107 (2) NCT03370770 (2) NCT03322696 (2) NCT00525473 (2) NCT03333343 (2) NCT03127449 (2) NCT01781026 (2) NCT02503722 (2) NCT00975871 (2) NCT03964233 (2) NCT03388099 (2) NCT02317016 (2) NCT03845270 (2) NCT03519958 (2) NCT03918304 (2) NCT02151721 (2) NCT02777658 (2) NCT01016444 (2) NCT02971501 (2) NCT03101254 (2) NCT03178617 (2) NCT01774721 (2) NCT03574753 (2) NCT01357655 (2) NCT01766713 (2) NCT02097225 (2) NCT00658164 (2) NCT03622593 (2) NCT02571036 (2) NCT00834665 (2) NCT00969137 (2) NCT02026011 (2) NCT03622580 (2) NCT03543683 (2) NCT01143493 (2) NCT03671538 (2) NCT04028778 (2) NCT00324961 (2) NCT01915576 (2) NCT02157883 (2) NCT01387022 (2) NCT03864042 (2) NCT03235245 (2) NCT03469960 (2) NCT02795884 (2) NCT00005541 (2) NCT01242813 (2) NCT02906020 (2) NCT03960645 (2) NCT00643058 (2) NCT03443336 (2) NCT02992860 (2) NCT02281760 (2) NCT02201602 (2) NCT04310007 (2) NCT03720665 (2) NCT04309019 (2) NCT00909532 (2) NCT00411944 (2) NCT01604681 (2) NCT01245062 (2) NCT00270231 (2) NCT03256136 (2) NCT03973918 (2) NCT00302692 (2) NCT00125281 (2) NCT02163733 (2) NCT02110407 (2) NCT00475176 (2) NCT03196882 (2) NCT01572818 (2) NCT02556333 (2) NCT04268550 (2) NCT02433717 (2) NCT03428126 (2) NCT01153763 (2) NCT02609776 (2) NCT01420211 (2) NCT03556176 (2) NCT03872440 (2) NCT01405079 (2) NCT03382795 (2) NCT02991950 (2) NCT00013598 (2) NCT03455764 (2) NCT02422628 (2) NCT03831932 (2) NCT03766490 (2) NCT02580474 (2) NCT00499577 (2) NCT02444884 (2) NCT01775943 (2) NCT03544814 (2) NCT01310036 (2) NCT01027663 (2) NCT01928160 (2) NCT01244438 (2) NCT00007150 (2) NCT04462081 (2) NCT02297425 (2) NCT02086071 (2) NCT01050400 (2) NCT03060590 (2) NCT01819428 (2) NCT02709668 (2) NCT02411448 (2) NCT03878719 (2) NCT04479306 (2) NCT03377023 (2) NCT01378026 (2) NCT00226551 (2) NCT03239145 (2) NCT04511533 (2) NCT02191891 (2) NCT04586270 (2) NCT04545710 (2) NCT02120222 (2) NCT02738593 (2) NCT00831272 (2) NCT04469543 (2) NCT00573495 (2) NCT04158544 (2) NCT00904150 (2) NCT02110056 (2) NCT02856893 (2) NCT02110043 (2) NCT02182986 (2) NCT04179890 (2) NCT00063232 (2) NCT02197234 (2) NCT03121235 (2) NCT01532089 (2) NCT03887169 (2) NCT02268864 (2) NCT01963845 (2) NCT00866736 (2) NCT03977194 (2) NCT03991013 (2) NCT02500927 (2) NCT02228382 (2) NCT02689570 (2) NCT01513785 (2) NCT02463435 (2) NCT03351361 (2) NCT04527549 (2) NCT03424759 (2) NCT02197247 (2) NCT02321046 (2) NCT04272034 (2) NCT04027647 (2) NCT02364609 (2) NCT02759835 (2) NCT04349865 (2) NCT00068159 (2) NCT00418015 (2) NCT04310397 (2) NCT03088176 (2) NCT03867175 (2) NCT00339209 (2) NCT00011258 (2) NCT01288430 (2) NCT01616199 (2) NCT03603262 (2) NCT03071705 (2) NCT00969930 (2) NCT00772408 (2) NCT02743468 (2) NCT00277342 (2) NCT04248829 (2) NCT01767454 (2) NCT00933127 (2) NCT03317873 (2) NCT03392246 (2) NCT01909453 (2) NCT03523104 (2) NCT00085917 (2) NCT02507921 (2) NCT03781752 (2) NCT03828422 (2) NCT02193282 (2) NCT03195452 (2) NCT02294487 (2) NCT01325441 (2) NCT02511106 (2) NCT02997501 (2) NCT04184921 (2) NCT00625092 (2) NCT01657786 (2) NCT01415011 (2) NCT02629523 (2) NCT01718847 (2) NCT02818023 (2) NCT00577707 (2) NCT01943422 (2) NCT00116636 (2) NCT01841463 (2) NCT04429542 (2) NCT03865511 (2) NCT01218477 (2) NCT03205267 (2) NCT02881320 (2) NCT01897480 (2) NCT02810990 (2) NCT04189757 (2) NCT01951001 (2) NCT04254939 (2) NCT03207867 (2) NCT00780949 (2) NCT03355768 (2) NCT00817089 (2) NCT02143466 (2) NCT04499053 (2) NCT01907776 (2) NCT00909727 (2) NCT01562028 (2) NCT03737253 (2) NCT00441974 (2) NCT02155465 (2) NCT04586335 (2) NCT00661999 (2) NCT02705339 (2) NCT04006340 (2) NCT04553887 (2) NCT03852290 (2) NCT02183922 (2) NCT03970239 (2) NCT00294372 (2) NCT03250676 (2) NCT03792074 (2) NCT00671892 (2) NCT00689182 (2) NCT00106379 (2) NCT01947023 (2) NCT00509652 (2) NCT03683251 (2) NCT02039986 (2) NCT03515837 (2) NCT04081688 (2) NCT03190005 (2) NCT01584648 (2) NCT02292654 (2) NCT03992456 (2) NCT03133546 (2) NCT01485809 (2) NCT01266967 (2) NCT02909712 (2) NCT00062764 (2) NCT01776684 (2) NCT03042221 (2) NCT01940809 (2) NCT01161537 (2) NCT01154816 (2) NCT01175759 (2) NCT01199731 (2) NCT02788058 (2) NCT03130452 (2) NCT01772732 (2) NCT02631447 (2) NCT02525692 (2) NCT02526537 (2) NCT03513666 (2) NCT02027961 (2) NCT03106779 (2) NCT04106544 (2) NCT04258943 (2) NCT00165984 (2) NCT00977470 (2) NCT02092974 (2) NCT03975231 (2) NCT01998295 (2) NCT03586453 (2) NCT02021305 (2) NCT03135197 (2) NCT00432016 (2) NCT03004625 (2) NCT03851445 (2) NCT04031898 (2) NCT04201418 (2) NCT01911507 (2) NCT03539224 (2) NCT01978236 (2) NCT00866177 (2) NCT00320879 (2) NCT00044304 (2) NCT01999179 (2) NCT00977730 (2) NCT02491775 (2) NCT00212147 (2) NCT02040064 (2) NCT00489385 (2) NCT01713023 (2) NCT04122729 (2) NCT03994393 (2) NCT02438722 (2) NCT02762448 (2) NCT00071903 (2) NCT00626223 (2) NCT01193829 (2) NCT03239340 (2) NCT02991274 (2) NCT02811354 (2) NCT03416530 (2) NCT02522988 (2) NCT00953706 (2) NCT02346955 (2) NCT03795688 (2) NCT02011945 (2) NCT00857675 (2) NCT00028262 (2) NCT02355431 (2) NCT02495233 (2) NCT04575415 (2) NCT03468985 (2) NCT00230087 (2) NCT02017600 (2) NCT04146298 (2) 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NCT01647711 (1) NCT03231722 (1) NCT03576937 (1) NCT04412070 (1) NCT00554866 (1) NCT03151161 (1) NCT01817166 (1) NCT02220855 (1) NCT02512627 (1) NCT04591197 (1) NCT03402048 (1) NCT04500704 (1) NCT02323724 (1) NCT01166126 (1) NCT03029858 (1) NCT04317599 (1) NCT00300573 (1) NCT00809211 (1) NCT01393730 (1) NCT02318368 (1) NCT02228369 (1) NCT01074398 (1) NCT04500717 (1) NCT03134131 (1) NCT01004497 (1) NCT02455167 (1) NCT02073279 (1) NCT02117817 (1) NCT00323687 (1) NCT01605981 (1) NCT01371955 (1) NCT04147767 (1) NCT04144257 (1) NCT03490123 (1) NCT04423185 (1) NCT02625337 (1) NCT03567629 (1) NCT03360929 (1) NCT00109278 (1) NCT04108156 (1) NCT02132598 (1) NCT00542451 (1) NCT01587573 (1) NCT00868465 (1) NCT01494402 (1) NCT00867139 (1) NCT03363139 (1) NCT01936051 (1) NCT02341131 (1) NCT00037076 (1) NCT00582907 (1) NCT02169869 (1) NCT03284684 (1) NCT04204473 (1) NCT01074359 (1) NCT01400191 (1) NCT04530565 (1) NCT03530319 (1) NCT04146402 (1) NCT02658682 (1) NCT04241835 (1) NCT03133234 (1) 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SNPMiner SNPMiner Trials (Home Page)


Report for Clinical Trial NCT04238624

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

A Pilot Study of the Addition of Cemiplimab, an Antibody to PD-1, to the Treatment of Subjects With BRAF-Mutant Anaplastic Thyroid Cancer Who Are No Longer Responding to Dabrafenib and Trametinib

This study is being done to see if adding the study drug, cemiplimab, to the standard therapy with dabrafenib and trametinib is an effective treatment against anaplastic thyroid cancer.

NCT04238624 Anaplastic Thyroid Cancer Thyroid Cancer BRAF Gene Mutation BRAF Mutation-Related Tumors
MeSH:Thyroid Neoplasms Thyroid Carcinoma, Anaplastic Thyroid Diseases
HPO:Abnormality of the thyroid gland Anaplastic thyroid carcinoma Neoplasm of the thyroid gland Thyroid adenoma Thyroid carcinoma Thyroid follicular adenoma

2 Interventions

Name: Dabrafenib

Description: Participants will receive dabrafenib 150 mg orally twice a day
Type: Drug
Group Labels: 1

BRAF-mutant ATC

Name: Trametinib

Description: Participants will receive trametinib 2 mg orally once a day
Type: Drug
Group Labels: 1

BRAF-mutant ATC


Primary Outcomes

Description: Response and progression will be evaluated by using criteria proposed in RECIST 1.1.

Measure: Overall Response Rate per RECIST 1.1 Criteria

Time: 2 years

Purpose: Treatment

Allocation: N/A

Single Group Assignment


There is one SNP

SNPs


1 V600E

Response and progression will be evaluated by using criteria proposed in RECIST 1.1.. Inclusion Criteria: - Pathological (histologically or cytologically) proven diagnosis of BRAF-V600E mutant ATC (a diagnosis that is noted to be consistent with ATC is acceptable) - Either Metastatic disease or locoregional disease that is considered not resectable for cure - Ideally a surgeon should determine that the disease is not resectable for cure, but this can also be done by any investigator - Patients must have measurable disease according to RECIST 1.1 criteria, defined as at least 1 lesion that can be accurately measured in at least 1 dimension (longest diameter to be recorded for nonnodal lesions and short axis for nodal lesions) as >/= 20 mm with conventional techniques or as >/= 10 mm with spiral CT scan, MRI, or calipers by clinical exam - Age >/= 18 years - Eastern Cooperative Oncology Group (ECOG) performance status /= 60) - Able to swallow and retain orally administered medication - Patient must have normal organ and marrow function as defined below: - Absolute neutrophil count >/=1.5 x 10^9/L - Hemoglobin >/=8 g/dL - Platelets >/=100 x 10^9/L - Serum bilirubin V600E ---

Sherman) - Active inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis) - History of primary immunodeficiency - History of allogeneic organ transplant - Known history of previous clinical diagnosis of active tuberculosis (this does not include a history of being PPD positive) Inclusion Criteria: - Pathological (histologically or cytologically) proven diagnosis of BRAF-V600E mutant ATC (a diagnosis that is noted to be consistent with ATC is acceptable) - Either Metastatic disease or locoregional disease that is considered not resectable for cure - Ideally a surgeon should determine that the disease is not resectable for cure, but this can also be done by any investigator - Patients must have measurable disease according to RECIST 1.1 criteria, defined as at least 1 lesion that can be accurately measured in at least 1 dimension (longest diameter to be recorded for nonnodal lesions and short axis for nodal lesions) as >/= 20 mm with conventional techniques or as >/= 10 mm with spiral CT scan, MRI, or calipers by clinical exam - Age >/= 18 years - Eastern Cooperative Oncology Group (ECOG) performance status /= 60) - Able to swallow and retain orally administered medication - Patient must have normal organ and marrow function as defined below: - Absolute neutrophil count >/=1.5 x 10^9/L - Hemoglobin >/=8 g/dL - Platelets >/=100 x 10^9/L - Serum bilirubin V600E ---



HPO Nodes


HPO:
HP:0000820: Abnormality of the thyroid gland
Genes 573
ZIC2 GLIS3 PTEN FOXH1 TRNL1 NODAL HESX1 PRKAR1A ALX4 LIMK1 IRS4 CTNNB1 HBB SIX3 TSHR LIG4 GP1BB MDM2 MLXIPL CDON SALL1 PAX8 PRKAR1A SEC24C TF POMC TG PRKAR1A BMP4 MMP14 TNFSF15 APOE CACNA1C ZBTB20 WFS1 THRA NKX2-5 TSHR GPC1 FGF8 TRIP13 DISP1 GAS1 IYD XRCC4 CDC73 CACNA1S FOXH1 BIRC3 ELN KMT2D MDM4 SCN4A GPR35 JMJD1C UFD1 CHEK2 TSHR MSH3 BAP1 COX2 TSC1 DLL1 TXNRD2 SIX3 EIF2AK3 NKX2-5 GTF2I MLH3 NSD1 FAN1 MCM8 SLC26A4 MSH2 TG FOXH1 TCF4 MSTO1 SDHC CDON IL12RB1 AIP TBX1 LHX3 SLC26A4 RCBTB1 LIFR GAS1 ACP5 TRNH MRAP SEMA3E SLC5A5 RASGRP1 CDC73 RET SEC23B APC CDH23 APC SPOP POLR1C IGH SIX3 NODAL GATA1 RET LHX4 HPD SHH DISP1 POU1F1 NKX2-1 GLI3 GLI2 ALMS1 FANCI ITCH RERE FMR1 DISP1 KLLN FASLG TWNK DLL1 PTEN SAA1 FOXP3 FGF8 MSTO1 TDGF1 TGFBR2 WRN UBR1 ABCC6 POLG SVBP LHX3 TRNS2 GLI2 FGF8 TRNS1 POU1F1 YY1 RAG2 POU3F4 CASR IFIH1 DUOXA2 IFNG FGFR1 PLAGL1 STAR JAG1 GNAS ZFP57 GNE OPA1 HABP2 DMXL2 NODAL GABRA3 CTLA4 PHF21A HBB USP9X ANAPC1 GNAS GATA6 ND4 PAX8 ND5 SUFU FAS TBCK IDH2 SLC6A17 CDON IL7R STAG2 ARL6IP6 APC BAP1 FLCN SIX3 COX1 MINPP1 RAI1 TRHR MST1 SMARCB1 PIK3CA WDR11 DDOST CHD7 CTNS RAG1 RNASEH2C PLAA ALMS1 ZIC2 FOXE1 FOXP1 PROP1 TTC37 DICER1 KRAS FGF8 POLR1D CCBE1 SHH POU1F1 PIK3CA SKIV2L IGSF1 TRNW STAG2 LEPR MMEL1 LIG4 NODAL POLR3A IRF5 BUB1B SLC26A4 PTCH1 SEC23B ADAMTSL1 ZIC2 PTEN HYMAI TRHR ZIC2 GAS1 GAS1 ECE1 SLC5A5 TRAF7 ROBO1 PTEN RNASEH2B TRNF DCLRE1C TDGF1 BTNL2 DUOXA2 FOXP3 HNF1B ABCC8 DYRK1A SPIB BCOR TGIF1 FLCN CDON DNM1L MARS1 KCNJ10 KCNJ18 NKX2-1 AKT1 KEAP1 TSHR NNT CDKN1A KATNIP KISS1R SAMHD1 DISP1 PTCH1 SASH1 SRGAP1 GLI2 ADA LRP4 TSHB EXOSC2 NKX2-1 GLI2 RET SLC25A4 C1S C1QBP APC DICER1 NRTN CLPB GLI3 GREM1 KCNJ10 BUB3 SMC1A GNAS DCLRE1C IDH1 MLH1 MC2R SUFU NPHS1 SOX3 FOXA2 USP9X SMO NRAS CDKN1B MEN1 KAT6B TONSL STAT1 JAK1 WDR4 PROP1 STAT5B PPP1R15B CHD7 SETD2 LMNA RREB1 MMP2 PROP1 CEP57 MEN1 BMPR1A PDGFB ARVCF GCH1 ATRX PMS1 EDNRB CLIP2 TBX1 LRBA NIN SIM1 PTRH2 KCNJ18 TRMT10A BAZ1B FUCA1 TP53 BRAF ADAR LHX4 RAI1 SOX3 TRNQ RRM2B HSD17B3 AFF4 TRH SMARCE1 APC RFC2 CDKN2A RET SIX3 TDGF1 THRB SEMA3C TSHR PDE4D CDKN2C TANGO2 SIX1 HESX1 IL18BP PTRH2 NSDHL FGFR1 PLCG2 TG CDON LEP GDNF FOXD3 KDM6A PRKCD MAGEL2 TBC1D24 INSR EDN3 TRNL2 RAI1 ZIC2 DCAF17 HESX1 GLI2 EPCAM MSH3 FOXE1 COX3 HRAS FOXH1 EXT2 MEN1 BCL10 STEAP3 ND1 GPR161 PIK3C2A PTEN ZFAT BMPR1A FGF8 HBB DMXL2 GABRD DNAJC19 POLG2 MTTP TRAPPC9 APC SLC12A3 KCNAB2 TGIF1 AIRE TPO USF3 PLVAP WFS1 PTCH1 TNPO3 PTCH1 GRM7 CDH23 TDGF1 LEPR SDHD IL2RA CLCNKB IL2RG HABP2 STAT3 SHH TERT TTC7A TWNK PIK3CA GLI2 SKI RPS20 GAS1 NF2 PROP1 HNF4A LHX4 FUT8 FAS RNASEH2A COMT TBX1 TGIF1 CDC73 RBM28 ENPP1 SUGCT GTF2IRD1 SHH PAX8 CDON AKT1 NNT PCSK1 IYD DEAF1 PTCH1 POU2AF1 ADAT3 FOXH1 TRNS1 THRB FOXE1 PROKR2 FLII MALT1 TCOF1 TSHR TGIF1 SEMA4A SALL1 TBX2 SLC26A4 EYA1 APC2 XRCC4 CTNS PIEZO1 PMM2 STUB1 NLRP1 LHX4 FDX2 ACP5 IL12A TDGF1 KCNJ11 TRNN SRD5A3 TRNW DLL1 TRNL1 SHH TPO AKT1 SGPL1 DICER1 TGIF1 FOXI1 TREX1 ITCH MSH6 SLC16A2 DUOX2 FOXE1 FOXP1 ND6 FGFR1 HSD17B3 TMEM67 BUB1 INSR POLG THRB ALG8 FMR1 ELN TSC2 SETBP1 RMRP SRY PAX8 DUOX2 TANGO2 NKX2-1 NKX2-5 SDHB NODAL TSHB PIK3CA TSHR TBL2 B3GLCT DLL1 ARNT2 CACNA1S TSHR DUOX2 KAT6B FOXE1 CDKN2B HIRA IQSEC2 DMPK LIG4 OTX2 GNAS PMS2 FOXI1 DLL1 CDKN1B PRDM16 CEP57 DNAH1 PDE4D DACT1 SEMA3D HLA-DRB1 TBL1X PPP1R15B MINPP1 STAT1 CASP10 DISP1
Protein Mutations 4
F11N K601E V600E V600K
SNP 0