Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry.
Name: This is a non-interventional study
Case-Control
There is one SNP
Identifying Leucocyte and Urine Biomarkers in Parkinson's Patients With LRRK2 G2385R Gene Variant. --- G2385R ---
LRRK2 G2385R Leucocyte and Urine Biomarker Study Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry. --- G2385R ---
LRRK2 G2385R Leucocyte and Urine Biomarker Study Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry. --- G2385R --- --- G2385R ---
Identification of monocyte-based biomarkers for LRRK2 G2385R variant. --- G2385R ---
Identification of urine-based biomarkers for LRRK2 G2385R variant. --- G2385R ---