The objective of the study is to assess the impact of genetic variation (especially polymorphisms of the gene coding endothelial nitric oxide synthase (eNOS) and the bradykinin B2 receptor gene) on venous and arterial responsiveness to vasodilators in healthy individuals without cardiovascular risk factors.
Name: sodium nitroprusside, bradykinin, acetylcholine
Type: DrugAllocation: Non-Randomized
Single Group Assignment
There is one SNP
Endothelium-Dependent Vasoreactivity in Nitric Oxide Synthase Gene (Glu298Asp) Polymorphism: Studies in Healthy Volunteers. --- Glu298Asp ---