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Report for Clinical Trial NCT00533754

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals. Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.

NCT00533754 Age-Related Macular Degeneration
MeSH: Macular Degeneration

1 Interventions

Name: drawing blood

Type: Procedure


Primary Outcomes

Measure: higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals

Secondary Outcomes

Measure: a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD

Purpose: Basic Science

Single Group Assignment


There is one SNP

SNPs


1 Y402H

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population. --- Y402H ---

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals. --- Y402H ---

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals. --- Y402H --- --- Y402H ---

An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD. higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals. --- Y402H ---



HPO Nodes