The purpose of this study is to determine whether BRAF V600E mutation in our patients with papillary thyroid cancer has an association with poor prognosis.
Name: BRAF V600E POSITIVITY
Description: BRAF V600E mutation analysis will be made using the tumor tissues of the patients with papillary thyroid cancer (3 sections of 7 mm from he paraffin blocks). And mutation positives and negatives will be identified.Type: GeneticBRAF V600E POSITIVITY
Allocation: Non-Randomized
Single Group Assignment
There is one SNP
Association Of Prognosis And BRAF V600E Mutations In Papillary Thyroid Carcinoma. --- V600E ---
BRAF V600E Mutations In Papillary Thyroid Carcinoma The purpose of this study is to determine whether BRAF V600E mutation in our patients with papillary thyroid cancer has an association with poor prognosis. --- V600E ---
BRAF V600E Mutations In Papillary Thyroid Carcinoma The purpose of this study is to determine whether BRAF V600E mutation in our patients with papillary thyroid cancer has an association with poor prognosis. --- V600E --- --- V600E ---
BRAF V600E MUTATION. --- V600E ---
Inclusion Criteria: - Patients with papillary thyroid cancer Exclusion Criteria: - Patients who do not want to be a part of this study Inclusion Criteria: - Patients with papillary thyroid cancer Exclusion Criteria: - Patients who do not want to be a part of this study Papillary Thyroid Carcinoma Carcinoma Thyroid Neoplasms Thyroid Cancer, Papillary Thyroid Diseases Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and BRAF V600E mutation is the most common genetic alteration identified in PTC, ranging from 25 to 80%, with the average rate about 45%. --- V600E ---
Various studies demonstrated a relationship between BRAF V600E mutation and aggressive characteristics of the cancer, including the worse patient prognosis. --- V600E ---
So the investigators will examine BRAF V600E mutation in our patients with PTC and try to assess the role of this mutation in prognosis and further management of the patients. --- V600E ---