SNPMiner Trials (Home Page)
Report for Clinical Trial NCT03237494
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
Estimation of the prevalence of Heretary Transthyretin-related Amyloidosis in a cohort of
patients with polyneuropathy or cardiomyopathy of undetermined etiology.
NCT03237494 Transthyretin Amyloidosis Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy Polyneuropathies Cardiomyopathies
Primary Outcomes Measure: Number of participants with hATTR among a cohort of participants with polyneuropathy and cardiomyopathy of no obvious etiology. Time: 1 day
Secondary Outcomes Measure: To establish biomarker/s in TTR positive cohort. Time: 1 day
Time Perspective: Prospective
There are 2 SNPs
Most common TTR variant involved
in the cardiac form of hATTR is Val122Ile. --- Val122Ile ---
Most common TTR variant involved in the neuropathic
form of hATTR is Val30Met. --- Val30Met ---