SNPMiner Trials by Shray Alag


SNPMiner SNPMiner Trials (Home Page)


Report for Clinical Trial NCT00972751

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

Investigation of Thioredoxin-1 Family Protein Expression in Rectal Cancer

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at protein expression in tumor tissue samples from patients with stage II or stage III rectal cancer enrolled in clinical trial SWOG-9304.

NCT00972751 Colorectal Cancer
MeSH:Rectal Neoplasms
HPO:Neoplasm of the rectum


Primary Outcomes

Measure: Expression of thioredoxin-1, thioredoxin-interacting protein, and hypoxia inducible factor-1 alpha

Time: upon testing of specimens

Measure: Correlation of expression of these proteins with tumor stage, disease-free survival, overall survival, and risk of recurrence

Time: upon provision of expression to Statistical Center

Time Perspective: Retrospective

Cohort


There is one SNP

SNPs


1 S9304A

S9304A Study of Protein Expression in Tumor Tissue Samples From Patients With Stage II or Stage III Rectal Cancer Enrolled in Clinical Trial SWOG-9304 RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. --- S9304A ---



HPO Nodes


HPO: