- Noncirrhotic Portal Hypertension (NCPH) is caused by liver diseases that increase pressure
in the blood vessels of the liver. It seems to start slowly and not have many warning signs.
Many people may not even know that they have a liver disease. There are no specific
treatments for NCPH.
- To learn more about how NCPH develops over time.
- People age 12 and older who have NCPH or are at risk for getting it. In the past year, they
cannot have had other types of liver disease that typically result in cirrhosis, liver
cancer, or active substance abuse.
- Participants will have 2 screening visits.
- Visit 1: to see if they have or may develop NCPH.
- Medical history
- Physical exam
- Urine and stool studies
- Abdominal ultrasound
- Fibroscan. Sound waves measure liver stiffness.
Description: natural history studyMeasure: To study the natural history of non cirrhotic portal hypertension. It is an ongoing study Time: Ongoing
There is one SNP
- Hemochromatosis as defined by presence of 3+ or 4+ stainable iron on liver biopsy or homozygosity for C282Y. --- C282Y ---