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Report for Clinical Trial NCT01487291

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients

At the Thrombophilia Clinic of the Hospital Federal dos Servidores do Estado do Rio de Janeiro there is a high prevalence of acute psychotic episodes, which allows the investigators to raise the suspicion that the thrombotic tendency or hypofibrinolysis play a role in the onset of the disease. It is striking that most of these patients, after some time on anticoagulants, no longer need to take psychiatric medication.

NCT01487291 Insulin Resistance Thrombophilia Psychosis
MeSH:Thrombophilia Insulin Resistance
HPO:Hypercoagulability Insulin resistance


Primary Outcomes

Description: The investigators' hypothesis is that a high prevalence of hypofibrinolysis markers will be probably found in psychotic patients.

Measure: Prevalence of hypofibrinolysis markers in psychotic patients

Time: One year

Secondary Outcomes

Description: The investigators are assessing clinical and laboratory markers of plasminogen activator imbalance in psychiatric patients who require electroconvulsive therapy, specifically patients with major depressive disorders and schizophrenia.

Measure: Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Patients who Need Electroconvulsive Therapy

Time: 2013-2014

Time Perspective: Cross-Sectional

Case Control


There is one SNP

SNPs


1 G20210A

This study intents to investigate the prevalence of hypofibrinolysis markers, such as PAI-1 4G/5G and 4G/4G, protein S deficiency, antiphospholipid antibodies and prothrombin G20210A, in psychotic patients. --- G20210A ---



HPO Nodes


HPO: