evaluate the combination therapy with Miglustat and enzyme replacement therapy (ERT) on Gaucher disease
Name: Miglustat
Name: ERT
Allocation: Non-Randomized
Parallel Assignment
There is one SNP
Case_Miglustat Inclusion Criteria: 1. Confirmed diagnosis of Gaucher Disease: blood test shown lack of beta- glucocerebrosidase, and found L444P homozygous on GBA gene. --- L444P ---
Control_normal Inclusion Criteria 1. Age 6-18 years 2. No significant physical, mental, or psychiatric problems Exclusion criteria 1. Children with eye disease (not include myopia, hyperopia, Astigmatism) Case_Miglustat Inclusion Criteria: 1. Confirmed diagnosis of Gaucher Disease: blood test shown lack of beta- glucocerebrosidase, and found L444P homozygous on GBA gene. --- L444P ---