The purpose of this study is to validate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.
Description: DNA was extracted from venous blood;genomic DNA underwent PCR amplification; finally, PCR products were purified and directly sequenced by Invitrogen Corp or Biosune Corp.Then ALDH2 genotype was distinguished depend on a G-to-A missense mutation on exon 12 of ALDH2 gene.
Measure: Number of patients with different ALDH2 genotype Time: 1-30 days after samples collectedCase-Control
There is one SNP
A Validation Study of The Relationship Between ALDH2 and Aortic Dissection The purpose of this study is to validate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection. --- Glu504Lys ---