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Report for Clinical Trial NCT03443336

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

Prospective Multi-center Surveillance Study on the Prevalence of Azole-resistant Aspergillus Spp. in Clinical Isolates ot Patients With Pulmonary Colonization or Invasive Infections in Switzerland

Prospective multi-center surveillance study on the prevalence of azole-resistant Aspergillus spp. in clinical isolates of patients with pulmonary colonization or invasive infections in Switzerland

NCT03443336 Pulmonary Aspergillosis
MeSH:Aspergillosis Pulmonary Aspergillosis


Primary Outcomes

Description: Distribution of antifungal susceptibility profile of all tracheal and urinary samples in clinical Aspergillus isolates

Measure: Azole-resistance in Aspergillus (A.) fumigatus

Time: start of study until end of study (July 2017 until December 2018)

Time Perspective: Prospective

Other


There are 2 SNPs

SNPs


1 L98H

These mutations, including TR34/L98H and TR46/Y121F/T289A have been identified in the environment and have been demonstrated to cause resistance to azole fungicides used in agriculture. --- L98H ---


2 Y121F

These mutations, including TR34/L98H and TR46/Y121F/T289A have been identified in the environment and have been demonstrated to cause resistance to azole fungicides used in agriculture. --- L98H --- --- Y121F ---



HPO Nodes